检索结果 - Jonathan Whittaker
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Structural resolution of a tandem hormone-binding element in the insulin receptor and its implications for design of peptide agonists 由 Brian J. Smith, Kun Huang, G.K.-W. Kong, Shu Jin Chan, Satoe H. Nakagawa, John G. Menting, Shi-Quan Hu, Jonathan Whittaker, Donald F. Steiner, Panayotis G. Katsoyannis, Colin W. Ward, Michael A. Weiss, Michael C. Lawrence
出版 2010Artigo -
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An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein 由 Michael D. Glidden, Khadijah Aldabbagh, Nelson B. Phillips, Kelley Carr, Yen-Shan Chen, Jonathan Whittaker, Manijeh Phillips, Nalinda P. Wickramasinghe, Nischay Rege, Mamuni Swain, Yi Peng, Yanwu Yang, Michael C. Lawrence, Vivien C. Yee, Faramarz Ismail‐Beigi, Michael A. Weiss
出版 2017Artigo -
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How insulin engages its primary binding site on the insulin receptor 由 John G. Menting, Jonathan Whittaker, Mai B. Margetts, Linda Whittaker, G.K.-W. Kong, Brian J. Smith, Christopher J.E. Watson, Lenka Žáková, Emília Kletvíková, Jiřı́ Jiráček, Shu Jin Chan, Donald F. Steiner, Guy Dodson, A.M. Brzozowski, Michael A. Weiss, Colin W. Ward, Michael C. Lawrence
出版 2013Artigo -
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Protective hinge in insulin opens to enable its receptor engagement 由 John G. Menting, Yanwu Yang, Shu Jin Chan, Nelson B. Phillips, Brian J. Smith, Jonathan Whittaker, Nalinda P. Wickramasinghe, Linda Whittaker, Vijay Pandyarajan, Zhu‐li Wan, Satya P. Yadav, Julie M. Carroll, Natalie Strokes, Charles T. Roberts, Faramarz Ismail‐Beigi, Wieslawa Milewski, Donald F. Steiner, Virander S. Chauhan, Colin W. Ward, Michael A. Weiss, Michael C. Lawrence
出版 2014Artigo
相关主题
Biology
Insulin
Biochemistry
Endocrinology
Insulin receptor
Insulin resistance
Receptor
Chemistry
Gene
Binding site
Mutagenesis
Cell biology
Ligand (biochemistry)
Molecular biology
Alanine
Alanine scanning
Amino acid
Biophysics
Computational biology
Genetics
Human insulin
Insulin receptor substrate
Internal medicine
Materials science
Medicine
Mutant
Ectodomain
GRB10
Mutation
Protein subunit