Resultats de la cerca - Jonathan Whittaker

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  1. 1
    High-Affinity Insulin Binding: Insulin Interacts with Two Receptor Ligand Binding Sites

    High-Affinity Insulin Binding: Insulin Interacts with Two Receptor Ligand Binding Sites per Linda Whittaker, Caili Hao, Wenbin Fu, Jonathan Whittaker

    Publicat 2008
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  2. 2
    Alanine-scanning Mutagenesis of a C-terminal Ligand Binding Domain of the Insulin Receptor α Subunit

    Alanine-scanning Mutagenesis of a C-terminal Ligand Binding Domain of the Insulin Receptor α Subunit per Dennis C. Mynarcik, Gui Qin Yu, Jonathan Whittaker

    Publicat 1996
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  3. 3
    Mapping of an NH--terminal Ligand Binding Site of the Insulin Receptor by Alanine Scanning Mutagenesis

    Mapping of an NH--terminal Ligand Binding Site of the Insulin Receptor by Alanine Scanning Mutagenesis per Paul F. Williams, Dennis C. Mynarcik, Gui Qin Yu, Jonathan Whittaker

    Publicat 1995
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  4. 4
    Identification of Common Ligand Binding Determinants of the Insulin and Insulin-like Growth Factor 1 Receptors

    Identification of Common Ligand Binding Determinants of the Insulin and Insulin-like Growth Factor 1 Receptors per Dennis C. Mynarcik, Paul F. Williams, Lauge Schäffer, Gui Qin Yu, Jonathan Whittaker

    Publicat 1997
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  5. 5
    Design and Folding of [Glu<sup>A4</sup>(O<sup>β</sup>Thr<sup>B30</sup>)]Insulin (“Ester Insulin”): A Minimal Proinsulin Surrogate that Can Be Chemically Converted into Human Insulin

    Design and Folding of [Glu<sup>A4</sup>(O<sup>β</sup>Thr<sup>B30</sup>)]Insulin (“Ester Insulin”): A Minimal Proinsulin Surrogate that Can Be Chemically Converted into Human Insuli... per Youhei Sohma, Qing‐Xin Hua, Jonathan Whittaker, Michael A. Weiss, Stephen B. H. Kent

    Publicat 2010
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  6. 6
    Identification of a Ligand-Binding Region of the Human Insulin Receptor Encoded by the Second Exon of the Gene

    Identification of a Ligand-Binding Region of the Human Insulin Receptor Encoded by the Second Exon of the Gene per Pierre De Meyts, Jiali Gu, Ronald M. Shymko, Bruce Kaplan, Graeme I. Bell, Jonathan Whittaker

    Publicat 1990
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  7. 7
    Overexpression of Insulin Receptors in Fibroblast and Ovary Cells Induces a Ligand-Mediated Transformed Phenotype

    Overexpression of Insulin Receptors in Fibroblast and Ovary Cells Induces a Ligand-Mediated Transformed Phenotype per Francesco Giorgino, Antonino Belfiore, Giovanni Milazzo, Angela Costantino, Betty A. Maddux, Jonathan Whittaker, Ira D. Goldfine, Riccardo Vigneri

    Publicat 1991
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  8. 8
    Higher-Resolution Structure of the Human Insulin Receptor Ectodomain: Multi-Modal Inclusion of the Insert Domain

    Higher-Resolution Structure of the Human Insulin Receptor Ectodomain: Multi-Modal Inclusion of the Insert Domain per Tristan I. Croll, Brian J. Smith, Mai B. Margetts, Jonathan Whittaker, Michael A. Weiss, Colin W. Ward, Michael C. Lawrence

    Publicat 2016
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  9. 9
    Structural resolution of a tandem hormone-binding element in the insulin receptor and its implications for design of peptide agonists

    Structural resolution of a tandem hormone-binding element in the insulin receptor and its implications for design of peptide agonists per Brian J. Smith, Kun Huang, G.K.-W. Kong, Shu Jin Chan, Satoe H. Nakagawa, John G. Menting, Shi-Quan Hu, Jonathan Whittaker, Donald F. Steiner, Panayotis G. Katsoyannis, Colin W. Ward, Michael A. Weiss, Michael C. Lawrence

    Publicat 2010
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  10. 10
    An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein

    An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein per Michael D. Glidden, Khadijah Aldabbagh, Nelson B. Phillips, Kelley Carr, Yen-Shan Chen, Jonathan Whittaker, Manijeh Phillips, Nalinda P. Wickramasinghe, Nischay Rege, Mamuni Swain, Yi Peng, Yanwu Yang, Michael C. Lawrence, Vivien C. Yee, Faramarz Ismail‐Beigi, Michael A. Weiss

    Publicat 2017
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  11. 11
    How insulin engages its primary binding site on the insulin receptor

    How insulin engages its primary binding site on the insulin receptor per John G. Menting, Jonathan Whittaker, Mai B. Margetts, Linda Whittaker, G.K.-W. Kong, Brian J. Smith, Christopher J.E. Watson, Lenka Žáková, Emília Kletvíková, Jiřı́ Jiráček, Shu Jin Chan, Donald F. Steiner, Guy Dodson, A.M. Brzozowski, Michael A. Weiss, Colin W. Ward, Michael C. Lawrence

    Publicat 2013
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  12. 12
    Protective hinge in insulin opens to enable its receptor engagement

    Protective hinge in insulin opens to enable its receptor engagement per John G. Menting, Yanwu Yang, Shu Jin Chan, Nelson B. Phillips, Brian J. Smith, Jonathan Whittaker, Nalinda P. Wickramasinghe, Linda Whittaker, Vijay Pandyarajan, Zhu‐li Wan, Satya P. Yadav, Julie M. Carroll, Natalie Strokes, Charles T. Roberts, Faramarz Ismail‐Beigi, Wieslawa Milewski, Donald F. Steiner, Virander S. Chauhan, Colin W. Ward, Michael A. Weiss, Michael C. Lawrence

    Publicat 2014
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