Søgeresultater - Jonathan P. DiNitto
- Showing 1 - 5 results of 5
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Structural Basis and Mechanism of Autoregulation in 3-Phosphoinositide-Dependent Grp1 Family Arf GTPase Exchange Factors af Jonathan P. DiNitto, Anna Delprato, Meng‐Tse Gabe Lee, Thomas C. Cronin, Shao Hui Huang, Adı́lson Guilherme, Michael Czech, David G. Lambright
Udgivet 2007Artigo -
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KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients af K.S. Gajiwala, Joe C. Wu, James G. Christensen, Gayatri D. Deshmukh, Wade Diehl, Jonathan P. DiNitto, Jessie M. English, Michael J. Greig, You-Ai He, Suzanne L. Jacques, Elizabeth A. Lunney, Michele McTigue, David A. Castillo Molina, Terri Quenzer, Peter A. Wells, Xiu Yu, Yan Zhang, Aihua Zou, Mark R. Emmett, Alan G. Marshall, Hui‐Min Zhang, George D. Demetri
Udgivet 2009Artigo -
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Discovery of a Selective Phosphoinositide-3-Kinase (PI3K)-γ Inhibitor (IPI-549) as an Immuno-Oncology Clinical Candidate af Catherine A. Evans, Tao Liu, André Lescarbeau, Somarajan Nair, Louis Grenier, Johan A. Pradeilles, Quentin Glenadel, Thomas T. Tibbitts, Ann Rowley, Jonathan P. DiNitto, Erin Brophy, Erin O’Hearn, Janid A. Ali, David G. Winkler, Stanley I. Goldstein, Patrick J. O’Hearn, Christian M. Martin, Jennifer Hoyt, John R. Soglia, Culver Cheung, Melissa Pink, Jennifer Proctor, Vito J. Palombella, Martin Tremblay, Alfredo Castro
Udgivet 2016Artigo -
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PI3K-δ and PI3K-γ Inhibition by IPI-145 Abrogates Immune Responses and Suppresses Activity in Autoimmune and Inflammatory Disease Models af David G. Winkler, L. Kerrie, Jonathan P. DiNitto, Janid A. Ali, Kerry White, Erin Brophy, Melissa Pink, Jennifer Proctor, Jennifer Lussier, Christian M. Martin, Jennifer Hoyt, Bonnie Tillotson, Erin L. Murphy, Alice R. Lim, Brian D. Thomas, John R. MacDougall, Pingda Ren, Yi Liu, Lian‐Sheng Li, Katti Jessen, Christian Fritz, Joi Dunbar, James R. Porter, Christian Rommel, Vito J. Palombella, Paul S. Changelian, Jeffery L. Kutok
Udgivet 2013Artigo
Søgeredskaber:
Relaterede emner
Biology
Cell biology
Signal transduction
Biochemistry
Cancer research
Biotechnology
Chemistry
Gene
In vivo
Medicine
PI3K/AKT/mTOR pathway
Pharmacology
Pleckstrin homology domain
Receptor
ADP ribosylation factor
Acquired immune system
Binding site
Biophysics
Cancer
Drug resistance
Endoplasmic reticulum
GTPase
Genetics
GiST
Golgi apparatus
Guanine nucleotide exchange factor
Haematopoiesis
Imatinib
Imatinib mesylate
Immune system