Canlyniadau Chwilio - Jonathan Maybaum
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Guanine nucleotide depletion and toxicity in mouse T lymphoma (S-49) cells. gan M. Cohen, Jonathan Maybaum, Wolfgang Sadée
Cyhoeddwyd 1981Artigo -
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Variations in patterns of DNA damage induced in human colorectal tumor cells by 5-fluorodeoxyuridine: implications for mechanisms of resistance and cytotoxicity. gan Christine E. Canman, Hsin‐Yao Tang, Daniel P. Normolle, Theodore S. Lawrence, Jonathan Maybaum
Cyhoeddwyd 1992Artigo -
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Selective radiosensitization of p53 mutant pancreatic cancer cells by combined inhibition of Chk1 and PARP1 gan Sean Vance, Erqi Liu, Lili Zhao, Joshua D. Parsels, Leslie A. Parsels, Jeffery L. Brown, Jonathan Maybaum, Theodore S. Lawrence, Meredith A. Morgan
Cyhoeddwyd 2011Artigo -
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Sensitization of Pancreatic Cancer Stem Cells to Gemcitabine by Chk1 Inhibition gan Venkatasubbaiah A. Venkatesha, Leslie A. Parsels, Joshua D. Parsels, Lili Zhao, Sonya Zabludoff, Diane M. Simeone, Jonathan Maybaum, Theodore S. Lawrence, Meredith A. Morgan
Cyhoeddwyd 2012Artigo -
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Sensitization of Pancreatic Cancers to Gemcitabine Chemoradiation by WEE1 Kinase Inhibition Depends on Homologous Recombination Repair gan Tasneem Kausar, Jason S. Schreiber, David Karnak, Leslie A. Parsels, Joshua D. Parsels, Mary A. Davis, Lili Zhao, Jonathan Maybaum, Theodore S. Lawrence, Meredith A. Morgan
Cyhoeddwyd 2015Artigo -
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Wee1 Kinase Inhibitor AZD1775 Radiosensitizes Hepatocellular Carcinoma Regardless of TP53 Mutational Status Through Induction of Replication Stress gan Kyle C. Cuneo, Meredith A. Morgan, Mary A. Davis, Leslie A. Parcels, Joshua Parcels, David Karnak, Caila Ryan, Na Liu, Jonathan Maybaum, Theodore S. Lawrence
Cyhoeddwyd 2016Artigo -
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Inhibition of Protein Phosphatase 2A Radiosensitizes Pancreatic Cancers by Modulating CDC25C/CDK1 and Homologous Recombination Repair gan Dongping Wei, Leslie A. Parsels, David Karnak, Mary A. Davis, Joshua D. Parsels, Amanda C. Marsh, Lili Zhao, Jonathan Maybaum, Theodore S. Lawrence, Yi Sun, Meredith A. Morgan
Cyhoeddwyd 2013Artigo -
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PARP1 Trapping and DNA Replication Stress Enhance Radiosensitization with Combined WEE1 and PARP Inhibitors gan Leslie A. Parsels, David Karnak, Joshua D. Parsels, Qiang Zhang, Jonathan Vélez-Padilla, Zachery R. Reichert, Daniel Wahl, Jonathan Maybaum, Mark J. O’Connor, Theodore S. Lawrence, Meredith A. Morgan
Cyhoeddwyd 2017Artigo -
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Combined Inhibition of Wee1 and PARP1/2 for Radiosensitization in Pancreatic Cancer gan David Karnak, Carl G. Engelke, Leslie A. Parsels, Tasneem Kausar, Dongping Wei, Jordan R. Robertson, Katherine B. Marsh, Mary A. Davis, Lili Zhao, Jonathan Maybaum, Theodore S. Lawrence, Meredith A. Morgan
Cyhoeddwyd 2014Artigo -
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Gemcitabine sensitization by checkpoint kinase 1 inhibition correlates with inhibition of a Rad51 DNA damage response in pancreatic cancer cells gan Leslie A. Parsels, Meredith A. Morgan, Daria M. Tanska, Joshua D. Parsels, Brian D. Palmer, R J Booth, William A. Denny, Christine E. Canman, Alan J. Kraker, Theodore S. Lawrence, Jonathan Maybaum
Cyhoeddwyd 2009Artigo -
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Dose Escalation Trial of the Wee1 Inhibitor Adavosertib (AZD1775) in Combination With Gemcitabine and Radiation for Patients With Locally Advanced Pancreatic Cancer gan Kyle C. Cuneo, Meredith A. Morgan, Vaibhav Sahai, Matthew J. Schipper, Leslie A. Parsels, Joshua D. Parsels, Theresa P. Devasia, Mahmoud Al-Hawaray, Clifford S. Cho, Hari Nathan, Jonathan Maybaum, Mark M. Zalupski, Theodore S. Lawrence
Cyhoeddwyd 2019Artigo -
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Mechanism of Radiosensitization by the Chk1/2 Inhibitor AZD7762 Involves Abrogation of the G2 Checkpoint and Inhibition of Homologous Recombinational DNA Repair gan Meredith A. Morgan, Leslie A. Parsels, Lili Zhao, Joshua D. Parsels, Mary A. Davis, Maria Hassan, Sankari Arumugarajah, Linda Hylander-Gans, Deborah Morosini, Diane M. Simeone, Christine E. Canman, Daniel P. Normolle, Sonya Zabludoff, Jonathan Maybaum, Theodore S. Lawrence
Cyhoeddwyd 2010Artigo -
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Sensitization of Pancreatic Cancer to Chemoradiation by the Chk1 Inhibitor MK8776 gan Carl G. Engelke, Leslie A. Parsels, Yushen Qian, Qiang Zhang, David Karnak, Jordan R. Robertson, Daria M. Tanska, Dongping Wei, Mary A. Davis, Joshua D. Parsels, Lili Zhao, Joel K. Greenson, Theodore S. Lawrence, Jonathan Maybaum, Meredith A. Morgan
Cyhoeddwyd 2013Artigo -
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Assessment of Chk1 Phosphorylation as a Pharmacodynamic Biomarker of Chk1 Inhibition gan Leslie A. Parsels, Yushen Qian, Daria M. Tanska, Marisa Gross, Lili Zhao, Maria Hassan, Sankari Arumugarajah, Joshua D. Parsels, Linda Hylander-Gans, Diane M. Simeone, Deborah Morosini, Jeffrey L. Brown, Sonya Zabludoff, Jonathan Maybaum, Theodore S. Lawrence, Meredith A. Morgan
Cyhoeddwyd 2011Artigo
Offerynnau Chwilio:
Pynciau Perthynol
Biology
Medicine
Cancer
Cancer research
Cell cycle
Internal medicine
Pancreatic cancer
Genetics
Biochemistry
DNA
Chemistry
Gemcitabine
Oncology
CHEK1
Cell cycle checkpoint
Cyclin-dependent kinase 1
DNA damage
Wee1
Gene
Homologous recombination
Immunology
Molecular biology
Pharmacology
Radiation therapy
Cell
Cell biology
Cell culture
DNA repair
Olaparib
PARP inhibitor