Canlyniadau Chwilio - Jonathan Hasselmann

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  1. 1
    Human iPSC‐derived microglia: A growing toolset to study the brain's innate immune cells

    Human iPSC‐derived microglia: A growing toolset to study the brain's innate immune cells gan Jonathan Hasselmann, Mathew Blurton‐Jones

    Cyhoeddwyd 2020
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    Revisão
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  2. 2
    Consistent induction of chronic experimental autoimmune encephalomyelitis in C57BL/6 mice for the longitudinal study of pathology and repair

    Consistent induction of chronic experimental autoimmune encephalomyelitis in C57BL/6 mice for the longitudinal study of pathology and repair gan Jonathan Hasselmann, Hawra Karim, Anna J. Khalaj, Subir Ghosh, Seema K. Tiwari‐Woodruff

    Cyhoeddwyd 2017
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    Artigo
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  3. 3
    Development and validation of a simplified method to generate human microglia from pluripotent stem cells

    Development and validation of a simplified method to generate human microglia from pluripotent stem cells gan Amanda McQuade, Morgan Coburn, Christina Tu, Jonathan Hasselmann, Hayk Davtyan, Mathew Blurton‐Jones

    Cyhoeddwyd 2018
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  4. 4
    Chronic demyelination-induced seizures

    Chronic demyelination-induced seizures gan Andrew Lapato, Jenny I. Szu, Jonathan Hasselmann, Anna J. Khalaj, Devin K. Binder, Seema K. Tiwari‐Woodruff

    Cyhoeddwyd 2017
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  5. 5
    Repeated Mild Closed Head Injuries Induce Long-Term White Matter Pathology and Neuronal Loss That Are Correlated With Behavioral Deficits

    Repeated Mild Closed Head Injuries Induce Long-Term White Matter Pathology and Neuronal Loss That Are Correlated With Behavioral Deficits gan Eric Gold, Vitaly Vasilevko, Jonathan Hasselmann, Casey Tiefenthaler, Danny Hoa, Kasuni H. Ranawaka, David H. Cribbs, B. Cummings

    Cyhoeddwyd 2018
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  6. 6
    Impact of MMP-2 and MMP-9 enzyme activity on wound healing, tumor growth and RACPP cleavage

    Impact of MMP-2 and MMP-9 enzyme activity on wound healing, tumor growth and RACPP cleavage gan Dina V. Hingorani, Csilla N. Lippert, Jessica L. Crisp, Elamprakash N. Savariar, Jonathan Hasselmann, Christopher Kuo, Quyen T. Nguyen, Roger Y. Tsien, Michael Whitney, Lesley G. Ellies

    Cyhoeddwyd 2018
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  7. 7
    Plaque-associated human microglia accumulate lipid droplets in a chimeric model of Alzheimer’s disease

    Plaque-associated human microglia accumulate lipid droplets in a chimeric model of Alzheimer’s disease gan Christel Claes, Emma Danhash, Jonathan Hasselmann, Jean Paul Chadarevian, Sepideh Kiani Shabestari, Whitney England, Tau En Lim, Jorge Luis Silva Hidalgo, Robert C. Spitale, Hayk Davtyan, Mathew Blurton‐Jones

    Cyhoeddwyd 2021
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  8. 8
    Harnessing human iPSC-microglia for CNS-wide delivery of disease-modifying proteins

    Harnessing human iPSC-microglia for CNS-wide delivery of disease-modifying proteins gan Jean Paul Chadarevian, Hayk Davtyan, Alina L Chadarevian, Jasmine Nguyen, Joia K. Capocchi, Lauren Le, Adrian Escobar, Talar Chadarevian, Malek Mansour, Ekaterina Deynega, Michael Mgerian, Christina Tu, Sepideh Kiani Shabestari, William Carlen-Jones, Ghazaleh Eskandari‐Sedighi, Jonathan Hasselmann, Robert C. Spitale, Mathew Blurton‐Jones

    Cyhoeddwyd 2025
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    Artigo
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  9. 9
    Therapeutic potential of human microglia transplantation in a chimeric model of CSF1R-related leukoencephalopathy

    Therapeutic potential of human microglia transplantation in a chimeric model of CSF1R-related leukoencephalopathy gan Jean Paul Chadarevian, Jonathan Hasselmann, Alina Lahian, Joia K. Capocchi, Adrian Escobar, Tau En Lim, Lauren Le, Christina Tu, Jasmine Nguyen, Sepideh Kiani Shabestari, William Carlen-Jones, Sunil Gandhi, Guojun Bu, David Hume, Clare Pridans, Zbigniew K. Wszołek, Robert C. Spitale, Hayk Davtyan, Mathew Blurton‐Jones

    Cyhoeddwyd 2024
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  10. 10
    The P522R protective variant of PLCG2 promotes the expression of antigen presentation genes by human microglia in an Alzheimer's disease mouse model

    The P522R protective variant of PLCG2 promotes the expression of antigen presentation genes by human microglia in an Alzheimer's disease mouse model gan Christel Claes, Whitney England, Emma Danhash, Sepideh Kiani Shabestari, Amit Jairaman, Jean Paul Chadarevian, Jonathan Hasselmann, Andy P. Tsai, Morgan Coburn, Jessica Sanchez, Tau En Lim, Jorge Luis Silva Hidalgo, Christina Tu, Michael D. Cahalan, Bruce T. Lamb, Gary E. Landreth, Robert C. Spitale, Mathew Blurton‐Jones, Hayk Davtyan

    Cyhoeddwyd 2022
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  11. 11
    Development of a Chimeric Model to Study and Manipulate Human Microglia In Vivo

    Development of a Chimeric Model to Study and Manipulate Human Microglia In Vivo gan Jonathan Hasselmann, Morgan Coburn, Whitney England, Dario X. Figueroa Velez, Sepideh Kiani Shabestari, Christina Tu, Amanda McQuade, Mahshad Kolahdouzan, Karla Echeverria, Christel Claes, Taylor Nakayama, Ricardo Azevedo, Nicole G. Coufal, Claudia Z. Han, B. Cummings, Hayk Davtyan, Christopher K. Glass, Luke M. Healy, Sunil Gandhi, Robert C. Spitale, Mathew Blurton‐Jones

    Cyhoeddwyd 2019
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    Artigo
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  12. 12
    Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice

    Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice gan Sepideh Kiani Shabestari, Samuel Morabito, Emma Danhash, Amanda McQuade, Jessica Sanchez, Emily Miyoshi, Jean Paul Chadarevian, Christel Claes, Morgan Coburn, Jonathan Hasselmann, Jorge Luis Silva Hidalgo, Kayla Nhi Tran, Alessandra Cadete Martini, Winston Chang Rothermich, Jesse R. Pascual, Elizabeth Head, David Hume, Clare Pridans, Hayk Davtyan, Vivek Swarup, Mathew Blurton‐Jones

    Cyhoeddwyd 2022
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  13. 13
    Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer’s disease

    Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer’s disease gan Amanda McQuade, You Jung Kang, Jonathan Hasselmann, Amit Jairaman, Alexandra Sotelo, Morgan Coburn, Sepideh Kiani Shabestari, Jean Paul Chadarevian, Gianna Fote, Christina Tu, Emma Danhash, Jorge Sá Silva, Eric Martínez, Carl W. Cotman, G. Aleph Prieto, Leslie M. Thompson, Joan S. Steffan, Ian F. Smith, Hayk Davtyan, Michael D. Cahalan, Hansang Cho, Mathew Blurton‐Jones

    Cyhoeddwyd 2020
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  14. 14
    Engineering an inhibitor-resistant human CSF1R variant for microglia replacement

    Engineering an inhibitor-resistant human CSF1R variant for microglia replacement gan Jean Paul Chadarevian, Sonia I. Lombroso, Graham C. Peet, Jonathan Hasselmann, Christina Tu, Dave E. Marzan, Joia K. Capocchi, Freddy S Purnell, Kelsey M Nemec, Alina Lahian, Adrian Escobar, Whitney England, V Sai Chaluvadi, Carleigh A. O’Brien, Fazeela Yaqoob, William H. Aisenberg, Matias Porras-Paniagua, Mariko L. Bennett, Hayk Davtyan, Robert C. Spitale, Mathew Blurton‐Jones, F. Chris Bennett

    Cyhoeddwyd 2022
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    Artigo
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