Resultats de la cerca - Jonathan Clayden

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  1. 1
    Fluorinated compounds present opportunities for drug discovery

    Fluorinated compounds present opportunities for drug discovery per Jonathan Clayden

    Publicat 2019
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  2. 2
    Screw sense and screw sensibility: communicating information by conformational switching in helical oligomers

    Screw sense and screw sensibility: communicating information by conformational switching in helical oligomers per David T. J. Morris, Jonathan Clayden

    Publicat 2023
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  3. 3
    Medium‐Sized‐Ring Analogues of Dibenzodiazepines by a Conformationally Induced Smiles Ring Expansion

    Medium‐Sized‐Ring Analogues of Dibenzodiazepines by a Conformationally Induced Smiles Ring Expansion per Romain Costil, Quentin Lefebvre, Jonathan Clayden

    Publicat 2017
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  4. 4
    Dynamic foldamer chemistry

    Dynamic foldamer chemistry per Bryden A. F. Le Bailly, Jonathan Clayden

    Publicat 2016
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  5. 5
    Asymmetric α-arylation of amino acids

    Asymmetric α-arylation of amino acids per Daniel J. Leonard, John W. Ward, Jonathan Clayden

    Publicat 2018
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  6. 6
    Refoldable Foldamers: Global Conformational Switching by Deletion or Insertion of a Single Hydrogen Bond

    Refoldable Foldamers: Global Conformational Switching by Deletion or Insertion of a Single Hydrogen Bond per Bryden A. F. Le Bailly, Liam Byrne, Jonathan Clayden

    Publicat 2016
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  7. 7
    Competing Hydrogen-Bond Polarities in a Dynamic Oligourea Foldamer: A Molecular Spring Torsion Balance

    Competing Hydrogen-Bond Polarities in a Dynamic Oligourea Foldamer: A Molecular Spring Torsion Balance per Romina Wechsel, Matej Žabka, John W. Ward, Jonathan Clayden

    Publicat 2018
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  8. 8
    De novo design of discrete, stable 310-helix peptide assemblies

    De novo design of discrete, stable 310-helix peptide assemblies per Prasun Kumar, Neil G. Paterson, Jonathan Clayden, Derek N. Woolfson

    Publicat 2022
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  9. 9
    Switching imidazole reactivity by dynamic control of tautomer state in an allosteric foldamer

    Switching imidazole reactivity by dynamic control of tautomer state in an allosteric foldamer per David Tilly, Jean-Paul Heeb, Simon J. Webb, Jonathan Clayden

    Publicat 2023
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  10. 10
    Induction of Unexpected Left‐Handed Helicity by an N‐Terminal <scp>L</scp>‐Amino Acid in an Otherwise Achiral Peptide Chain

    Induction of Unexpected Left‐Handed Helicity by an N‐Terminal <scp>L</scp>‐Amino Acid in an Otherwise Achiral Peptide Chain per Robert A. Brown, Tommaso Marcelli, Matteo De Poli, Jordi Solà, Jonathan Clayden

    Publicat 2012
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  11. 11
    Chemoenzymatic Synthesis of Substituted Azepanes by Sequential Biocatalytic Reduction and Organolithium-Mediated Rearrangement

    Chemoenzymatic Synthesis of Substituted Azepanes by Sequential Biocatalytic Reduction and Organolithium-Mediated Rearrangement per Wojciech Zawodny, Sarah L. Montgomery, James R. Marshall, James Finnigan, Nicholas J. Turner, Jonathan Clayden

    Publicat 2018
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  12. 12
    Left-Handed Helical Preference in an Achiral Peptide Chain Is Induced by an <scp>l</scp>-Amino Acid in an N-Terminal Type II β-Turn

    Left-Handed Helical Preference in an Achiral Peptide Chain Is Induced by an <scp>l</scp>-Amino Acid in an N-Terminal Type II β-Turn per Matteo De Poli, Marta De Zotti, James Raftery, Juan A. Aguilar, Gareth A. Morris, Jonathan Clayden

    Publicat 2013
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  13. 13
    Foldamer‐Mediated Remote Stereocontrol: &gt;1,60 Asymmetric Induction

    Foldamer‐Mediated Remote Stereocontrol: &gt;1,60 Asymmetric Induction per Liam Byrne, Jordi Solà, Thomas Boddaert, Tommaso Marcelli, Ralph W. Adams, Gareth A. Morris, Jonathan Clayden

    Publicat 2013
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  14. 14
    Conformational Switching of a Foldamer in a Multicomponent System by pH-Filtered Selection between Competing Noncovalent Interactions

    Conformational Switching of a Foldamer in a Multicomponent System by pH-Filtered Selection between Competing Noncovalent Interactions per Julien Brioche, Sarah J. Pike, Sofja Tshepelevitsh, Ivo Leito, Gareth A. Morris, Simon J. Webb, Jonathan Clayden

    Publicat 2015
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  15. 15
    Length-Dependent Formation of Transmembrane Pores by 3<sub>10</sub>-Helical α-Aminoisobutyric Acid Foldamers

    Length-Dependent Formation of Transmembrane Pores by 3<sub>10</sub>-Helical α-Aminoisobutyric Acid Foldamers per Jennifer E. Jones, Vincent Diemer, Catherine Adam, James Raftery, Rebecca E. Ruscoe, Jason T. Sengel, Mark I. Wallace, Antoine Bader, Scott L. Cockroft, Jonathan Clayden, Simon J. Webb

    Publicat 2015
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  16. 16
    Switchable foldamer ion channels with antibacterial activity

    Switchable foldamer ion channels with antibacterial activity per Anna D. Peters, Stefan Borsley, Flavio della Sala, Dominic F. Cairns‐Gibson, Marios Leonidou, Jonathan Clayden, George F. S. Whitehead, Íñigo J. Vitórica‐Yrezábal, Eriko Takano, John Burthem, Scott L. Cockroft, Simon J. Webb

    Publicat 2020
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