Resultats de la cerca - Jonathan Clark

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  1. 1
    Lysophosphatidylinositol-Acyltransferase-1 (LPIAT1) Is Required to Maintain Physiological Levels of PtdIns and PtdInsP2 in the Mouse

    Lysophosphatidylinositol-Acyltransferase-1 (LPIAT1) Is Required to Maintain Physiological Levels of PtdIns and PtdInsP2 in the Mouse per Karen E. Anderson, Anna Kielkowska, Tom N. Durrant, Véronique Juvin, Jonathan Clark, Len Stephens, Phillip T. Hawkins

    Publicat 2013
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  2. 2
    A new approach to measuring phosphoinositides in cells by mass spectrometry

    A new approach to measuring phosphoinositides in cells by mass spectrometry per Anna Kielkowska, Izabella Niewczas, Karen E. Anderson, Tom N. Durrant, Jonathan Clark, Len Stephens, Phillip T. Hawkins

    Publicat 2013
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  3. 3
    Retroviral gp70 immune complexes in NZB x NZW F2 mice with murine lupus nephritis.

    Retroviral gp70 immune complexes in NZB x NZW F2 mice with murine lupus nephritis. per Shozo Izui, Patricia J. McConahey, Jonathan Clark, L M Hang, I. Hara, Frank J. Dixon

    Publicat 1981
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  4. 4
    Structure of Lipid Kinase p110β/p85β Elucidates an Unusual SH2-Domain-Mediated Inhibitory Mechanism

    Structure of Lipid Kinase p110β/p85β Elucidates an Unusual SH2-Domain-Mediated Inhibitory Mechanism per Xuxiao Zhang, Oscar Vadas, Olga Perišić, Karen E. Anderson, Jonathan Clark, Phillip T. Hawkins, Len Stephens, Roger Williams

    Publicat 2011
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  5. 5
    <i>Dictyostelium</i> uses ether‐linked inositol phospholipids for intracellular signalling

    <i>Dictyostelium</i> uses ether‐linked inositol phospholipids for intracellular signalling per Jonathan Clark, Robert R. Kay, Anna Kielkowska, Izabella Niewczas, Louise Fets, David Oxley, Len Stephens, Phillip T. Hawkins

    Publicat 2014
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  6. 6
    Dynamics of mTORC1 activation in response to amino acids

    Dynamics of mTORC1 activation in response to amino acids per Maria Manifava, Matthew D. Smith, Sergio Rotondo, Simon Walker, Izabella Niewczas, Roberto Zoncu, Jonathan Clark, Nicholas T. Ktistakis

    Publicat 2016
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  7. 7
    Two distinct functions for PI3-kinases in macropinocytosis

    Two distinct functions for PI3-kinases in macropinocytosis per Oliver Hoeller, Parvin Bolourani, Jonathan Clark, Len Stephens, Phillip T. Hawkins, Orion D. Weiner, Gerald Weeks, Robert R. Kay

    Publicat 2013
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  8. 8
    Age-related changes in the physical properties, cross-linking, and glycation of collagen from mouse tail tendon

    Age-related changes in the physical properties, cross-linking, and glycation of collagen from mouse tail tendon per Melanie Stammers, Irina M. Ivanova, Izabella Niewczas, Anne Segonds-Pichon, Matthew D. Streeter, David A. Spiegel, Jonathan Clark

    Publicat 2020
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  9. 9
    Diagnostic Reference Levels based on clinical indications in computed tomography: a literature review

    Diagnostic Reference Levels based on clinical indications in computed tomography: a literature review per Graciano Paulo, John Damilakis, Virginia Tsapaki, Alexander Schegerer, Jacques Repussard, Werner Jaschke, Guy Frija, Monika Hierath, Jonathan Clark

    Publicat 2020
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  10. 10
    Quantification of PtdInsP3 molecular species in cells and tissues by mass spectrometry

    Quantification of PtdInsP3 molecular species in cells and tissues by mass spectrometry per Jonathan Clark, Karen E. Anderson, Véronique Juvin, Trevor Smith, Fredrik Karpe, Michael J.O. Wakelam, Len Stephens, Phillip T. Hawkins

    Publicat 2011
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  11. 11
    GPCR activation of Ras and PI3Kγ in neutrophils depends on PLCβ2/β3 and the RasGEF RasGRP4

    GPCR activation of Ras and PI3Kγ in neutrophils depends on PLCβ2/β3 and the RasGEF RasGRP4 per Sabine Suire, Charlotte Lécureuil, Karen E. Anderson, George Damoulakis, Izabella Niewczas, Keith Davidson, Hervé Guillou, Dingxin Pan, Jonathan Clark, Phillip T. Hawkins, Len Stephens

    Publicat 2012
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  12. 12
    Membrane characteristics tune activities of endosomal and autophagic human VPS34 complexes

    Membrane characteristics tune activities of endosomal and autophagic human VPS34 complexes per Yohei Ohashi, Shirley Tremel, Glenn R. Masson, Lauren McGinney, Jérôme Boulanger, Ksenia Rostislavleva, Christopher M. Johnson, Izabella Niewczas, Jonathan Clark, Roger Williams

    Publicat 2020
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  13. 13
    PI3K p110δ regulates T-cell cytokine production during primary and secondary immune responses in mice and humans

    PI3K p110δ regulates T-cell cytokine production during primary and secondary immune responses in mice and humans per Dalya R. Soond, Elisa Bjørgo, Kristine Moltu, Verity Q. Dale, Daniel T. Patton, Knut Martin Torgersen, Fiona P. Galleway, Breda M. Twomey, Jonathan Clark, J. S. Hill Gaston, Kjetil Taskén, Peter Bunyard, Klaus Okkenhaug

    Publicat 2010
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  14. 14
    Rejuvenating conventional dendritic cells and T follicular helper cell formation after vaccination

    Rejuvenating conventional dendritic cells and T follicular helper cell formation after vaccination per Marisa Stebegg, Alexandre Bignon, Danika L. Hill, Alyssa Silva-Cayetano, Christel Krueger, Ine Vanderleyden, Silvia Innocentin, Louis Boon, Jiong Wang, Martin S. Zand, James Dooley, Jonathan Clark, Adrian Liston, Edward J Carr, Michelle A. Linterman

    Publicat 2020
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  15. 15
    PI3Kδ hyper-activation promotes development of B cells that exacerbate Streptococcus pneumoniae infection in an antibody-independent manner

    PI3Kδ hyper-activation promotes development of B cells that exacerbate Streptococcus pneumoniae infection in an antibody-independent manner per Anne‐Katrien Stark, Anita Chandra, Krishnendu Chakraborty, Rafeah Alam, Valentina Carbonaro, Jonathan Clark, Srividya Sriskantharajah, Glyn Bradley, Alex Richter, Edward Banham-Hall, Menna R. Clatworthy, Sergey Nejentsev, J. Hamblin, Edith M. Hessel, Alison M. Condliffe, Klaus Okkenhaug

    Publicat 2018
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  16. 16
    Glycation changes molecular organization and charge distribution in type I collagen fibrils

    Glycation changes molecular organization and charge distribution in type I collagen fibrils per Sneha B. Bansode, Uliana Bashtanova, Rui Li, Jonathan Clark, Karin H. Müller, Anna M. Puszkarska, Ieva Goldberga, Holly H. Chetwood, David G. Reid, Lucy J. Colwell, Jeremy N. Skepper, Catherine M. Shanahan, Georg Schitter, Patrick Mesquida, Melinda J. Duer

    Publicat 2020
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  17. 17
    An open label trial of nemiralisib, an inhaled PI3 kinase delta inhibitor for the treatment of Activated PI3 kinase Delta Syndrome

    An open label trial of nemiralisib, an inhaled PI3 kinase delta inhibitor for the treatment of Activated PI3 kinase Delta Syndrome per Malcolm Begg, Augustin Amour, Emily Jarvis, Teresa Tang, Sara Santos Franco, Andrew Want, Misba Beerahee, Disala Fernando, Yakshitha Karkera, Clare R. Sander, Thomas Southworth, Dave Singh, Jonathan Clark, Sergey Nejentsev, Klaus Okkenhaug, Alison M. Condliffe, Anita Chandra, Anthony Cahn, Edward Hall

    Publicat 2023
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  18. 18
    Kinase-independent synthesis of 3-phosphorylated phosphoinositides by a phosphotransferase

    Kinase-independent synthesis of 3-phosphorylated phosphoinositides by a phosphotransferase per Glenn F. W. Walpole, Jonathan Pacheco, Neha Chauhan, Jonathan Clark, Karen E. Anderson, Y.M. Abbas, Danielle Brabant-Kirwan, Fernando Montaño-Rendón, Zetao Liu, Hongxian Zhu, John H. Brumell, Alexander Deiters, Len Stephens, Phillip T. Hawkins, Gerald Hammond, Sergio Grinstein, Gregory D. Fairn

    Publicat 2022
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  19. 19
    Insulin resistance uncoupled from dyslipidemia due to C-terminal PIK3R1 mutations

    Insulin resistance uncoupled from dyslipidemia due to C-terminal PIK3R1 mutations per Isabel Huang‐Doran, Patsy R Tomlinson, Felicity Payne, Alexandra T. Gast, Alison Sleigh, William Bottomley, J. Ieuan Harris, Allan Daly, Nuno Rocha, Simon A. Rudge, Jonathan Clark, Albert Kwok, Stefano Romeo, Emma McCann, Barbara Müksch, Mehul Dattani, Stefano Zucchini, Michael J.O. Wakelam, Lazaros C. Foukas, David B. Savage, Rinki Murphy, Stephen O’Rahilly, Inês Barroso, Robert K. Semple

    Publicat 2016
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  20. 20
    PTEN Regulates PI(3,4)P2 Signaling Downstream of Class I PI3K

    PTEN Regulates PI(3,4)P2 Signaling Downstream of Class I PI3K per Mouhannad Malek, Anna Kielkowska, Tamara Chessa, Karen E. Anderson, David Barneda, Pınar Pir, Hiroki Nakanishi, Satoshi Eguchi, Atsushi Koizumi, Junko Sasaki, Véronique Juvin, Vladimir Yu Kiselev, Izabella Niewczas, Alexander Gray, Alexandre Valayer, Dominik Spensberger, Marine Imbert, Sérgio Luís Felisbino, Tomonori Habuchi, Sören Beinke, Sabina Cosulich, Nicolas Le Novère, Takehiko Sasaki, Jonathan Clark, Phillip T. Hawkins, Len Stephens

    Publicat 2017
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