Výsledky vyhledávání - Jonas Ecker

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  1. 1
    Combination drug screen identifies synergistic drug interaction of BCL-XL and class I histone deacetylase inhibitors in MYC-amplified medulloblastoma cells

    Combination drug screen identifies synergistic drug interaction of BCL-XL and class I histone deacetylase inhibitors in MYC-amplified medulloblastoma cells Autor Simon Zeuner, Johanna Vollmer, Romain Sigaud, Sina Oppermann, Heike Peterziel, Dina ElHarouni, Ina Oehme, Olaf Witt, Till Milde, Jonas Ecker

    Vydáno 2024
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  2. 2
    Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma

    Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma Autor Jonas Ecker, Ina Oehme, Ralph Mazitschek, Andrey Korshunov, Marcel Kool, Thomas Hielscher, Judit Kiss, Florian Selt, Carina Konrad, Marco Lodrini, Hedwig E. Deubzer, Andreas von Deimling, Andreas E. Kulozik, Stefan M. Pfister, Olaf Witt, Till Milde

    Vydáno 2015
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  3. 3
    Response to trametinib treatment in progressive pediatric low-grade glioma patients

    Response to trametinib treatment in progressive pediatric low-grade glioma patients Autor Florian Selt, Cornelis M. van Tilburg, Brigitte Bison, Philipp Sievers, Inga Harting, Jonas Ecker, Kristian W. Pajtler, Felix Sahm, Annabelle Bahr, Michèle Simon, David Jones, Lennart Well, Victor‐Felix Mautner, David Capper, Pablo Hernáiz Driever, Astrid Gnekow, Stefan M. Pfister, Olaf Witt, Till Milde

    Vydáno 2020
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  4. 4
    Establishment and application of a novel patient-derived KIAA1549:BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing

    Establishment and application of a novel patient-derived KIAA1549:BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing Autor Florian Selt, Juliane Hohloch, Thomas Hielscher, Felix Sahm, David Capper, Andrey Korshunov, Diren Usta, Sebastian Brabetz, Johannes Ridinger, Jonas Ecker, Ina Oehme, Jan Gronych, Viktoria Marquardt, David Pauck, Heidi Bächli, Charles D. Stiles, Andreas von Deimling, Marc Remke, Martin U. Schuhmann, Stefan M. Pfister, Tilman Brummer, David Jones, Olaf Witt, Till Milde

    Vydáno 2016
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  5. 5
    The Senescence-associated Secretory Phenotype Mediates Oncogene-induced Senescence in Pediatric Pilocytic Astrocytoma

    The Senescence-associated Secretory Phenotype Mediates Oncogene-induced Senescence in Pediatric Pilocytic Astrocytoma Autor Juliane L. Buhl, Florian Selt, Thomas Hielscher, Romain Guiho, Jonas Ecker, Felix Sahm, Johannes Ridinger, Dennis Riehl, Diren Usta, Britta Ismer, Alexander C. Sommerkamp, Juan Pedro Martı́nez-Barberá, Annika K. Wefers, Marc Remke, Daniel Picard, Stefan Pusch, Jan Gronych, Ina Oehme, Cornelis M. van Tilburg, Marcel Kool, Daniela Kühn, David Capper, Andreas von Deimling, Martin U. Schuhmann, Christel Herold‐Mende, Andrey Korshunov, Tilman Brummer, Stefan M. Pfister, David Jones, Olaf Witt, Till Milde

    Vydáno 2018
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  6. 6
    Primary intracranial spindle cell sarcoma with rhabdomyosarcoma-like features share a highly distinct methylation profile and DICER1 mutations

    Primary intracranial spindle cell sarcoma with rhabdomyosarcoma-like features share a highly distinct methylation profile and DICER1 mutations Autor Christian Koelsche, Martin Mynarek, Daniel Schrimpf, Luca Bertero, Jonathan Serrano, Felix Sahm, David Reuß, Yanghao Hou, Daniel Baumhoer, Christian Vokuhl, Uta Flucke, Iver Petersen, Wolfgang Brück, Stefan Rutkowski, Sandro Casavilca‐Zambrano, Juan Luis García León, Rosdali Yesenia Diaz Coronado, Manfred Gessler, Òscar M. Tirado, Jaume Mora, Javier Alonso, Xavier García del Muro, Manel Esteller, Dominik Sturm, Jonas Ecker, Till Milde, Stefan M. Pfister, Andrey Korshunov, Matija Snuderl, Gunhild Mechtersheimer, Ulrich Schüller, David Jones, Andreas von Deimling

    Vydáno 2018
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  7. 7
    MAPK inhibitor sensitivity scores predict sensitivity driven by the immune infiltration in pediatric low-grade gliomas

    MAPK inhibitor sensitivity scores predict sensitivity driven by the immune infiltration in pediatric low-grade gliomas Autor Romain Sigaud, Thomas Albert, Caroline Heß, Thomas Hielscher, Nadine Winkler, Daniela Kocher, Carolin Walter, Daniel Münter, Florian Selt, Diren Usta, Jonas Ecker, Angela Brentrup, Martin Hasselblatt, Christian Thomas, Julian Varghese, David Capper, Ulrich W. Thomale, Pablo Hernáiz Driever, Michèle Simon, Svea Horn, Nina Annika Herz, Arend Koch, Felix Sahm, Stefan Hamelmann, Augusto Faria Andrade, Nada Jabado, Martin U. Schuhmann, Antoinette Y. N. Schouten–van Meeteren, Eelco W. Hoving, Tilman Brummer, Cornelis M. van Tilburg, Stefan M. Pfister, Olaf Witt, David Jones, Kornelius Kerl, Till Milde

    Vydáno 2023
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  8. 8
    Functional Precision Medicine Identifies New Therapeutic Candidates for Medulloblastoma

    Functional Precision Medicine Identifies New Therapeutic Candidates for Medulloblastoma Autor Jessica M. Rusert, Edwin F. Juarez, Sebastian Brabetz, James Jensen, Alexandra Garancher, Lianne Q. Chau, Silvia K. Tacheva-Grigorova, Sameerah Wahab, Yoko T. Udaka, Darren Finlay, Huriye Seker‐Cin, Brendan Reardon, Susanne Gröbner, Jonathan Serrano, Jonas Ecker, Lin Qi, Mari Kogiso, Yuchen Du, Patricia Baxter, Jacob J. Henderson, Michael E. Berens, Kristiina Vuori, Till Milde, Yoon-Jae Cho, Xiao‐Nan Li, James M. Olson, Iris Reyes, Matija Snuderl, Terence C. Wong, David Dimmock, Shareef Nahas, Denise Malicki, John R. Crawford, Michael L. Levy, Eliezer M. Van Allen, Stefan M. Pfister, Pablo Tamayo, Marcel Kool, Jill P. Mesirov, Robert J. Wechsler‐Reya

    Vydáno 2020
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  9. 9
    Cross-Species Genomics Reveals Oncogenic Dependencies in ZFTA/C11orf95 Fusion–Positive Supratentorial Ependymomas

    Cross-Species Genomics Reveals Oncogenic Dependencies in ZFTA/C11orf95 Fusion–Positive Supratentorial Ependymomas Autor Tuyu Zheng, David R. Ghasemi, Konstantin Okonechnikov, Andrey Korshunov, Martin Sill, Kendra K. Maaß, Patricia Benites Goncalves da Silva, Marina Ryzhova, Johannes Gojo, Damian Stichel, Amir Arabzade, Robert Kupp, Julia Benzel, Shinichiro Taya, Toma Adachi, Ryo Shiraishi, Nicolas U. Gerber, Dominik Sturm, Jonas Ecker, Philipp Sievers, Florian Selt, Rebecca Chapman, Christine Haberler, Dominique Figarella-Branger, Guido Reifenberger, Gudrun Fleischhack, Stefan Rutkowski, Andrew M. Donson, Vijay Ramaswamy, David Capper, David W. Ellison, Christel Herold‐Mende, Ulrich Schüller, Sebastian Brandner, Pablo Hernáiz Driever, Johan M. Kros, Matija Snuderl, Till Milde, Richard G. Grundy, Mikio Hoshino, Stephen C. Mack, Richard J. Gilbertson, David Jones, Marcel Kool, Andreas von Deimling, Stefan M. Pfister, Felix Sahm, Daisuke Kawauchi, Kristian W. Pajtler

    Vydáno 2021
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  10. 10
    Glioneuronal tumor with ATRX alteration, kinase fusion and anaplastic features (GTAKA): a molecularly distinct brain tumor type with recurrent NTRK gene fusions

    Glioneuronal tumor with ATRX alteration, kinase fusion and anaplastic features (GTAKA): a molecularly distinct brain tumor type with recurrent NTRK gene fusions Autor Henri Bogumil, Martin Sill, Daniel Schrimpf, Britta Ismer, Christina Blume, Ramin Rahmanzade, Felix Hinz, Asan Cherkezov, Rouzbeh Banan, Dennis Friedel, David Reuß, Florian Selt, Jonas Ecker, Till Milde, Kristian W. Pajtler, Jens Schittenhelm, Jürgen Hench, Stephan Frank, Henning B. Boldt, Bjarne Winther Kristensen, David Scheie, Linea Cecilie Melchior, Viola Olesen, Astrid Sehested, Daniel R. Boué, Zied Abdullaev, Laveniya Satgunaseelan, Ina Kurth, Annekatrin Seidlitz, Christine L. White, Ho‐Keung Ng, Zhifeng Shi, Christine Haberler, Martina Deckert, Marco Timmer, Roland Goldbrunner, Arnault Tauziède‐Espariat, Pascale Varlet, Sebastian Brandner, Sanda Alexandrescu, Matija Snuderl, Kenneth Aldape, Andrey Korshunov, Olaf Witt, Christel Herold‐Mende, Andreas Unterberg, Wolfgang Wick, Stefan M. Pfister, Andreas von Deimling, David Jones, Felix Sahm, Philipp Sievers

    Vydáno 2023
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  11. 11
    PATZ1 fusions define a novel molecularly distinct neuroepithelial tumor entity with a broad histological spectrum

    PATZ1 fusions define a novel molecularly distinct neuroepithelial tumor entity with a broad histological spectrum Autor Karam Al-Halabi, Damian Stichel, Philipp Sievers, Heike Peterziel, Alexander C. Sommerkamp, Dominik Sturm, Andrea Wittmann, Martin Sill, Natalie Jäger, Pengbo Beck, Kristian W. Pajtler, Matija Snuderl, George Jour, Michael DeLorenzo, Allison Martin, Adam Levy, Nagma Dalvi, Jordan R. Hansford, Nicholas G. Gottardo, Emmanuelle Uro‐Coste, Claude-Alain Maurage, Catherine Godfraind, Fanny Burel‐Vandenbos, Torsten Pietsch, Christof M. Kramm, Maria Filippidou, Antonis Kattamis, Chris Jones, Ingrid Øra, Torben Stamm Mikkelsen, Michal Zápotocký, David Sumerauer, David Scheie, Martin G. McCabe, Pieter Wesseling, Bastiaan B.J. Tops, Mariëtte E.G. Kranendonk, Matthias A. Karajannis, Nancy Bouvier, Elli Papaemmanuil, Hildegard Dohmen, Till Acker, Katja von Hoff, Simone Schmid, Evelina Miele, Katharina Filipski, Lidija Kitanovski, Lenka Krsková, Johannes Gojo, Christine Haberler, Frank Alvaro, Jonas Ecker, Florian Selt, Till Milde, Olaf Witt, Ina Oehme, Marcel Kool, Andreas von Deimling, Andrey Korshunov, Stefan M. Pfister, Felix Sahm, David Jones

    Vydáno 2021
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  12. 12
    The molecular landscape of ETMR at diagnosis and relapse

    The molecular landscape of ETMR at diagnosis and relapse Autor Sander Lambo, Susanne Gröbner, Tobias Rausch, Sebastian M. Waszak, Christin Schmidt, Aparna Gorthi, July Carolina Romero, Monika Mauermann, Sebastian Brabetz, Sonja Krausert, Ivo Buchhalter, Jan Köster, Danny A. Zwijnenburg, Martin Sill, Jens-Martin Hübner, Norman Mack, Benjamin Schwalm, Marina Ryzhova, Volker Hovestadt, Simon Papillon‐Cavanagh, Jennifer A. Chan, Pablo Landgraf, Ben Ho, Till Milde, Olaf Witt, Jonas Ecker, Felix Sahm, David Sumerauer, David W. Ellison, Brent A. Orr, Anna Darabi, Christine Haberler, Dominique Figarella‐Branger, Pieter Wesseling, Jens Schittenhelm, Marc Remke, Michael D. Taylor, Maria João Gil‐da‐Costa, Maria Łastowska, Wiesława Grajkowska, Martin Hasselblatt, Péter Hauser, Torsten Pietsch, Emmanuelle Uro‐Coste, Franck Bourdeaut, Julien Masliah‐Planchon, Valérie Rigau, Sanda Alexandrescu, Stephan Wolf, Xiao-Nan Li, Ulrich Schüller, Matija Snuderl, Matthias A. Karajannis, Felice Giangaspero, Nada Jabado, Andreas von Deimling, David Jones, Jan Korbel, Katja von Hoff, Peter Lichter, Annie Huang, Alexander J. R. Bishop, Stefan M. Pfister, Andrey Korshunov, Marcel Kool

    Vydáno 2019
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  13. 13
    Sarcoma classification by DNA methylation profiling

    Sarcoma classification by DNA methylation profiling Autor Christian Koelsche, Daniel Schrimpf, Damian Stichel, Martin Sill, Felix Sahm, David Reuß, Mirjam Blattner, Barbara C. Worst, Christoph E. Heilig, Katja Beck, Peter Horak, Simon Kreutzfeldt, Elke Paff, Sebastian Stark, Pascal D. Johann, Florian Selt, Jonas Ecker, Dominik Sturm, Kristian W. Pajtler, Annekathrin Reinhardt, Annika K. Wefers, Philipp Sievers, Azadeh Ebrahimi, Abigail K. Suwala, Francisco Fernández‐Klett, Belén Casalini, Andrey Korshunov, Volker Hovestadt, F. Kommoss, Mark Kriegsmann, Matthias Schick, Melanie Bewerunge‐Hudler, Till Milde, Olaf Witt, Andreas E. Kulozik, Marcel Kool, Laura Romero‐Pérez, Thomas G. P. Grünewald, Thomas Kirchner, Wolfgang Wick, Michael Platten, Andreas Unterberg, Matthias Uhl, Amir Abdollahi, Jürgen Debus, Burkhard Lehner, Christian Thomas, Martin Hasselblatt, Werner Paulus, Christian Hartmann, Ori Staszewski, Marco Prinz, Jürgen Hench, Stephan Frank, Yvonne M.H. Versleijen‐Jonkers, Marije E. Weidema, Thomas Mentzel, Klaus Griewank, Enrique de Álava, Juan Díaz‐Martín, Miguel Á. Idoate, Kenneth Tou En Chang, Sharon Y. Y. Low, Adrián Cuevas-Bourdier, Michel Mittelbronn, Martin Mynarek, Stefan Rutkowski, Ulrich Schüller, Viktor Mautner, Jens Schittenhelm, Jonathan Serrano, Matija Snuderl, Reinhard Büttner, Thomas Klingebiel, Rolf Buslei, Manfred Gessler, Pieter Wesseling, Winand N.M. Dinjens, Sebastian Brandner, Zane Jaunmuktane, Iben Lyskjær, Peter Schirmacher, Albrecht Stenzinger, Benedikt Brors, Hanno Glimm, Christoph Heining, Òscar M. Tirado, Miguel Sáinz‐Jaspeado, Jaume Mora, Javier Alonso, Xavier García del Muro, Sebastián Morán, Manel Esteller, Jamal Benhamida, Marc Ladanyi, Eva Wardelmann, Cristina R. Antonescu, Adrienne M. Flanagan, Uta Dirksen, Peter Hohenberger

    Vydáno 2021
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