Resultats de la cerca - Jon Read

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  1. 1
    Effect of different γ-subunit isoforms on the regulation of AMPK

    Effect of different γ-subunit isoforms on the regulation of AMPK per Robin Willows, Naveenan Navaratnam, Ana Lima, Jon Read, David Carling

    Publicat 2017
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  2. 2
    Chloroquine Binds in the Cofactor Binding Site ofPlasmodium falciparum Lactate Dehydrogenase

    Chloroquine Binds in the Cofactor Binding Site ofPlasmodium falciparum Lactate Dehydrogenase per Jon Read, Kay W. Wilkinson, R. Tranter, Richard B. Sessions, R.L. Brady

    Publicat 1999
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  3. 3
    Screening Ultra-Large Encoded Compound Libraries Leads to Novel Protein–Ligand Interactions and High Selectivity

    Screening Ultra-Large Encoded Compound Libraries Leads to Novel Protein–Ligand Interactions and High Selectivity per Gavin W. Collie, Matthew Clark, Anthony D. Keefe, Andrew Madin, Jon Read, Emma L. Rivers, Ying Zhang

    Publicat 2024
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  4. 4
    Phosphorylation of AMPK by upstream kinases is required for activity in mammalian cells

    Phosphorylation of AMPK by upstream kinases is required for activity in mammalian cells per Robin Willows, Matthew J. Sanders, Bing Xiao, Bhakti Patel, Stephen R. Martin, Jon Read, J. Wilson, Julia A. Hubbard, S.J. Gamblin, David Carling

    Publicat 2017
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  5. 5
    Mapping the sugar dependency for rational generation of a DNA-RNA hybrid-guided Cas9 endonuclease

    Mapping the sugar dependency for rational generation of a DNA-RNA hybrid-guided Cas9 endonuclease per Fernando Orden Rueda, Michal Bista, Matthew D. Newton, Anne U. Goeppert, Maria Emanuela Cuomo, Euan Gordon, Felix Kröner, Jon Read, Jonathan D.J. Wrigley, David Rueda, Ben Taylor

    Publicat 2017
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  6. 6
    Potent and Selective Inhibitors of MTH1 Probe Its Role in Cancer Cell Survival

    Potent and Selective Inhibitors of MTH1 Probe Its Role in Cancer Cell Survival per Jason G. Kettle, Husam Alwan, Michal Bista, J. Breed, Nichola L. Davies, Kay Eckersley, Shaun Fillery, Kevin M. Foote, Louise Goodwin, David R. Jones, Helena Käck, Alan Lau, J. Willem M. Nissink, Jon Read, James S. Scott, Ben Taylor, Graeme E. Walker, Lisa Wissler, Marta Wylot

    Publicat 2016
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  7. 7
    Recurrent MLK4 Loss-of-Function Mutations Suppress JNK Signaling to Promote Colon Tumorigenesis

    Recurrent MLK4 Loss-of-Function Mutations Suppress JNK Signaling to Promote Colon Tumorigenesis per Anna A. Marusiak, Natalie L. Stephenson, Hayeon Baik, Eleanor W. Trotter, Yaoyong Li, Karen Blyth, Susan Mason, Phil Chapman, Lorena A. Puto, Jon Read, C. Brassington, Hannah Pollard, Chris Phillips, Isabelle Green, R. Overman, Matthew Collier, Ewelina Testoni, Crispin Miller, Tony Hunter, Owen J. Sansom, John Brognard

    Publicat 2015
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  8. 8
    Discovery of cofactor-specific, bactericidal <i>Mycobacterium tuberculosis</i> InhA inhibitors using DNA-encoded library technology

    Discovery of cofactor-specific, bactericidal <i>Mycobacterium tuberculosis</i> InhA inhibitors using DNA-encoded library technology per Holly H. Soutter, Paolo A. Centrella, Matthew Clark, John W. Cuozzo, Christoph E. Dumelin, Marie-Aude Guié, Sevan Habeshian, Anthony D. Keefe, Kaitlyn M. Kennedy, Eric A. Sigel, Dawn M. Troast, Ying Zhang, Andrew D. Ferguson, Gareth M. Davies, Eleanor Rachel Stead, J. Breed, Prashanti Madhavapeddi, Jon Read

    Publicat 2016
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  9. 9
    AMPK activation protects against diet-induced obesity through Ucp1-independent thermogenesis in subcutaneous white adipose tissue

    AMPK activation protects against diet-induced obesity through Ucp1-independent thermogenesis in subcutaneous white adipose tissue per Alice Pollard, Luís Martins, Phillip Muckett, Sanjay Khadayate, Aurélie Bornot, Maryam Clausen, Therése Admyre, Mikael Bjursell, Rebeca Fiadeiro, Laura Wilson, Chad Whilding, Vassilios N. Kotiadis, Michael R. Duchen, Daniel Sutton, Lucy Penfold, Alessandro Sardini, Mohammad Bohlooly‐Y, David M. Smith, Jon Read, Michael Snowden, Angela Woods, David Carling

    Publicat 2019
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  10. 10
    Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity

    Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity per Angus Cameron, Jon Read, R. Tranter, Victoria J. Winter, Richard B. Sessions, R.L. Brady, Livia Vivas, Anna Easton, Howard Kendrick, Simon L. Croft, David Barros, José Luís Lavandera, J.J. Martin, F. Risco, Silvestre Garcı́a-Ochoa, F.J. Gamo, Laura M. Sanz, Luisa León, José R. Ruiz, Raquel Gabarró, Araceli Mallo, Federico G. De las Heras

    Publicat 2004
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  11. 11
    EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex

    EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex per Jessie Hao-Ru Hsu, Timothy Rasmusson, James Robinson, Fiona Pachl, Jon Read, Sameer Kawatkar, Daniel H. O’Donovan, Sharan K. Bagal, Erin Code, Philip B. Rawlins, Argyrides Argyrou, Ronald Tomlinson, Ning Gao, Xiahui Zhu, Elisabetta Chiarparin, Kelly Jacques, Minhui Shen, Haley Woods, Emma Bednarski, David M. Wilson, Lisa Drew, M. Paola Castaldi, Stephen E. Fawell, Andrew Bloecher

    Publicat 2019
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