نتائج البحث - John Reader
- يعرض 1 - 6 نتائج من 6
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Inhibition of TYK2 and JAK1 Ameliorates Imiquimod-Induced Psoriasis-like Dermatitis by Inhibiting IL-22 and the IL-23/IL-17 Axis حسب Melissa Works, F Yin, Catherine Yin, Ying Ying Yiu, Kenneth Shew, Thanh-Thuy Tran, Nahoko Dunlap, Jennifer S. Lam, Timothy J. Mitchell, John Reader, Paula Stein, Annalisa D’Andrea
منشور في 2014Artigo -
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The Preclinical Pharmacology and Therapeutic Activity of the Novel CHK1 Inhibitor SAR-020106 حسب Michael I. Walton, Paul D. Eve, Angela Hayes, Melanie Valenti, Alexis de Haven Brandon, Gary Box, Kathy Boxall, G. Wynne Aherne, Suzanne A. Eccles, Florence I. Raynaud, D. H. Williams, John Reader, Ian Collins, Michelle D. Garrett
منشور في 2010Artigo -
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CCT244747 Is a Novel Potent and Selective CHK1 Inhibitor with Oral Efficacy Alone and in Combination with Genotoxic Anticancer Drugs حسب Mike I. Walton, Paul D. Eve, Angela Hayes, Melanie Valenti, Alexis K. de Haven Brandon, Gary Box, Albert Hallsworth, Elizabeth Smith, Kathy Boxall, Michael Lainchbury, Thomas P. Matthews, Yann Jamin, Simon P. Robinson, G. Wynne Aherne, John Reader, Louis Chesler, Florence I. Raynaud, Suzanne A. Eccles, Ian Collins, Michelle D. Garrett
منشور في 2012Artigo -
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The clinical development candidate CCT245737 is an orally active CHK1 inhibitor with preclinical activity in RAS mutant NSCLC and Eμ-MYC driven B-cell lymphoma حسب Mike I. Walton, Paul D. Eve, Angela Hayes, Alan T. Henley, Melanie Valenti, Alexis K. de Haven Brandon, Gary Box, Kathy Boxall, Matthew Tall, Karen E. Swales, Thomas P. Matthews, Tatiana McHardy, Michael Lainchbury, James Osborne, Jill V. Hunter, Neil D. Perkins, G. Wynne Aherne, John Reader, Florence I. Raynaud, Suzanne A. Eccles, Ian Collins, Michelle D. Garrett
منشور في 2015Artigo -
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Structure-Guided Evolution of Potent and Selective CHK1 Inhibitors through Scaffold Morphing حسب John Reader, Thomas P. Matthews, Suki Klair, Kwai-Ming J. Cheung, Jane Scanlon, Nicolas Proisy, Glynn Addison, John Ellard, Nelly Piton, Suzanne Taylor, Michael Cherry, Martin Fisher, Kathy Boxall, Samantha Burns, Michael I. Walton, Isaac M. Westwood, Angela Hayes, Paul D. Eve, Melanie Valenti, Alexis de Haven Brandon, Gary Box, Rob L. M. van Montfort, D. H. Williams, G. Wynne Aherne, Florence I. Raynaud, Suzanne A. Eccles, Michelle D. Garrett, Ian Collins
منشور في 2011Artigo
أدوات البحث:
موضوعات ذات صلة
Biochemistry
Medicine
Pharmacology
Biology
Chemistry
Internal medicine
Apoptosis
Biotechnology
CHEK1
Cancer
Cancer research
Cell cycle
Cell cycle checkpoint
Combinatorial chemistry
Cyclin-dependent kinase 1
Immunology
In vivo
Artificial intelligence
Bead
Biomedical engineering
Catalysis
Chemical space
Composite material
Computational biology
Computer science
DNA
DNA damage
Dermatology
Drug discovery
G2-M DNA damage checkpoint