检索结果 - John Parrington

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  1. 1
    TPC2 in Drug Development: Emerging Target for Cancer, Viral Infections, Cardiovascular Diseases, and Neurological Disorders

    TPC2 in Drug Development: Emerging Target for Cancer, Viral Infections, Cardiovascular Diseases, and Neurological Disorders 由 Abeer Alharbi, John Parrington

    出版 2025
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  2. 2
    Mammalian Sperm Contain a Ca2+-Sensitive Phospholipase C Activity That Can Generate InsP3 from PIP2 Associated with Intracellular Organelles

    Mammalian Sperm Contain a Ca2+-Sensitive Phospholipase C Activity That Can Generate InsP3 from PIP2 Associated with Intracellular Organelles 由 Anne Rice, John Parrington, Keith T. Jones, Karl Swann

    出版 2000
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  3. 3
    A mammalian sperm cytosolic phospholipase C activity generates inositol trisphosphate and causes Ca<sup>2+</sup> release in sea urchin egg homogenates

    A mammalian sperm cytosolic phospholipase C activity generates inositol trisphosphate and causes Ca<sup>2+</sup> release in sea urchin egg homogenates 由 Keith T. Jones, Caroline Cruttwell, John Parrington, Karl Swann

    出版 1998
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  4. 4
    The pattern of localization of the putative oocyte activation factor, phospholipase C , in uncapacitated, capacitated, and ionophore-treated human spermatozoa

    The pattern of localization of the putative oocyte activation factor, phospholipase C , in uncapacitated, capacitated, and ionophore-treated human spermatozoa 由 Patricia Grasa, Kevin Coward, Claire Young, John Parrington

    出版 2008
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  5. 5
    Flipping the switch: How a sperm activates the egg at fertilization

    Flipping the switch: How a sperm activates the egg at fertilization 由 John Parrington, Lianne C. Davis, Antony Galione, Gary M. Wessel

    出版 2007
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  6. 6
    Different Ca2+-releasing abilities of sperm extracts compared with tissue extracts and phospholipase C isoforms in sea urchin egg homogenate and mouse eggs

    Different Ca2+-releasing abilities of sperm extracts compared with tissue extracts and phospholipase C isoforms in sea urchin egg homogenate and mouse eggs 由 Keith T. Jones, Miho Matsuda, John Parrington, Matilda Katan, Karl Swann

    出版 2000
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  7. 7
    Phospholipase C zeta undergoes dynamic changes in its pattern of localization in sperm during capacitation and the acrosome reaction

    Phospholipase C zeta undergoes dynamic changes in its pattern of localization in sperm during capacitation and the acrosome reaction 由 Claire Young, Patricia Grasa, Kevin Coward, Lianne C. Davis, John Parrington

    出版 2008
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  8. 8
    TPCs: Endolysosomal channels for Ca<sup>2+</sup> mobilization from acidic organelles triggered by NAADP

    TPCs: Endolysosomal channels for Ca<sup>2+</sup> mobilization from acidic organelles triggered by NAADP 由 Michael X. Zhu, Jianjie Ma, John Parrington, Antony Galione, A. Mark Evans

    出版 2010
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  9. 9
    Targeting Two-Pore Channels: Current Progress and Future Challenges

    Targeting Two-Pore Channels: Current Progress and Future Challenges 由 Xuhui Jin, Yuxuan Zhang, Abeer Alharbi, Ali Hanbashi, Ali Alhoshani, John Parrington

    出版 2020
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  10. 10
    Two-pore Channels Form Homo- and Heterodimers

    Two-pore Channels Form Homo- and Heterodimers 由 Katja Rietdorf, Tim M. Funnell, Margarida Ruas, Jennifer Heinemann, John Parrington, Antony Galione

    出版 2011
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  11. 11
    Oocyte activation, phospholipase C zeta and human infertility

    Oocyte activation, phospholipase C zeta and human infertility 由 Junaid Kashir, Björn Heindryckx, Céline Jones, Petra De Sutter, John Parrington, Kevin Coward

    出版 2010
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  12. 12
    Calcium signaling via two-pore channels: local or global, that is the question

    Calcium signaling via two-pore channels: local or global, that is the question 由 Michael X. Zhu, Jianjie Ma, John Parrington, Peter Calcraft, Antony Galione, Allan M. Evans

    出版 2009
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  13. 13
    TPC2 Proteins Mediate Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP)- and Agonist-evoked Contractions of Smooth Muscle

    TPC2 Proteins Mediate Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP)- and Agonist-evoked Contractions of Smooth Muscle 由 Nezahat Tugba Durlu‐Kandilci, Margarida Ruas, Kai‐Ting Chuang, Alison F. Brading, John Parrington, Antony Galione

    出版 2010
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  14. 14
    Phospholipase Cζ, the trigger of egg activation in mammals, is present in a non-mammalian species

    Phospholipase Cζ, the trigger of egg activation in mammals, is present in a non-mammalian species 由 Kevin Coward, Chris P. Ponting, H-Y Chang, Olivia Hibbitt, Peter Savolainen, Keith T. Jones, John Parrington

    出版 2005
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  15. 15
    The acid test: the discovery of two-pore channels (TPCs) as NAADP-gated endolysosomal Ca2+ release channels

    The acid test: the discovery of two-pore channels (TPCs) as NAADP-gated endolysosomal Ca2+ release channels 由 Antony Galione, Allan M. Evans, Jianjie Ma, John Parrington, Abdelilah Arredouani, Xiaotong Cheng, Michael X. Zhu

    出版 2009
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  16. 16
    Ca<sup>2+</sup>‐stimulated adenylyl cyclase isoform AC1 is preferentially expressed in guinea‐pig sino‐atrial node cells and modulates the <i>I</i><sub>f</sub> pacemaker current

    Ca<sup>2+</sup>‐stimulated adenylyl cyclase isoform AC1 is preferentially expressed in guinea‐pig sino‐atrial node cells and modulates the <i>I</i><sub>f</sub> pacemaker current... 由 Paul A. D. Mattick, John Parrington, Efe Odia, A Simpson, Thomas P. Collins, Derek A. Terrar

    出版 2007
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  17. 17
    Characterization of two heterozygous mutations of the oocyte activation factor phospholipase C zeta (PLCζ) from an infertile man by use of minisequencing of individual sperm and expression in somatic cells

    Characterization of two heterozygous mutations of the oocyte activation factor phospholipase C zeta (PLCζ) from an infertile man by use of minisequencing of individual sperm and ex... 由 Junaid Kashir, M. Konstantinidis, Céline Jones, Björn Heindryckx, Petra De Sutter, John Parrington, Dagan Wells, Kevin Coward

    出版 2012
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  18. 18
    Bidirectional Ca2+ signaling occurs between the endoplasmic reticulum and acidic organelles

    Bidirectional Ca2+ signaling occurs between the endoplasmic reticulum and acidic organelles 由 Anthony J. Morgan, Lianne C. Davis, Siegfried Wagner, Alexander M. Lewis, John Parrington, Grant C. Churchill, Antony Galione

    出版 2013
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  19. 19
    Photoaffinity Labeling of High Affinity Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP)-Binding Proteins in Sea Urchin Egg

    Photoaffinity Labeling of High Affinity Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP)-Binding Proteins in Sea Urchin Egg 由 Timothy F. Walseth, Yaping Lin-Moshier, Pooja Jain, Margarida Ruas, John Parrington, Antony Galione, Jonathan S. Marchant, James T. Slama

    出版 2011
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  20. 20
    Expression of Inositol 1,4,5-Trisphosphate Receptors in Mouse Oocytes and Early Embryos: The Type I Isoform Is Upregulated in Oocytes and Downregulated after Fertilization

    Expression of Inositol 1,4,5-Trisphosphate Receptors in Mouse Oocytes and Early Embryos: The Type I Isoform Is Upregulated in Oocytes and Downregulated after Fertilization 由 John Parrington, Sophie Brind, Humbert De Smedt, Ratthi Gangeswaran, F. Anthony Lai, Richard J.H. Wojcikiewicz, John Carroll

    出版 1998
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