Výsledky vyhledávání - John Parrington

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  1. 1
    TPC2 in Drug Development: Emerging Target for Cancer, Viral Infections, Cardiovascular Diseases, and Neurological Disorders

    TPC2 in Drug Development: Emerging Target for Cancer, Viral Infections, Cardiovascular Diseases, and Neurological Disorders Autor Abeer Alharbi, John Parrington

    Vydáno 2025
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  2. 2
    Mammalian Sperm Contain a Ca2+-Sensitive Phospholipase C Activity That Can Generate InsP3 from PIP2 Associated with Intracellular Organelles

    Mammalian Sperm Contain a Ca2+-Sensitive Phospholipase C Activity That Can Generate InsP3 from PIP2 Associated with Intracellular Organelles Autor Anne Rice, John Parrington, Keith T. Jones, Karl Swann

    Vydáno 2000
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  3. 3
    A mammalian sperm cytosolic phospholipase C activity generates inositol trisphosphate and causes Ca<sup>2+</sup> release in sea urchin egg homogenates

    A mammalian sperm cytosolic phospholipase C activity generates inositol trisphosphate and causes Ca<sup>2+</sup> release in sea urchin egg homogenates Autor Keith T. Jones, Caroline Cruttwell, John Parrington, Karl Swann

    Vydáno 1998
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  4. 4
    The pattern of localization of the putative oocyte activation factor, phospholipase C , in uncapacitated, capacitated, and ionophore-treated human spermatozoa

    The pattern of localization of the putative oocyte activation factor, phospholipase C , in uncapacitated, capacitated, and ionophore-treated human spermatozoa Autor Patricia Grasa, Kevin Coward, Claire Young, John Parrington

    Vydáno 2008
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  5. 5
    Flipping the switch: How a sperm activates the egg at fertilization

    Flipping the switch: How a sperm activates the egg at fertilization Autor John Parrington, Lianne C. Davis, Antony Galione, Gary M. Wessel

    Vydáno 2007
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  6. 6
    Different Ca2+-releasing abilities of sperm extracts compared with tissue extracts and phospholipase C isoforms in sea urchin egg homogenate and mouse eggs

    Different Ca2+-releasing abilities of sperm extracts compared with tissue extracts and phospholipase C isoforms in sea urchin egg homogenate and mouse eggs Autor Keith T. Jones, Miho Matsuda, John Parrington, Matilda Katan, Karl Swann

    Vydáno 2000
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  7. 7
    Phospholipase C zeta undergoes dynamic changes in its pattern of localization in sperm during capacitation and the acrosome reaction

    Phospholipase C zeta undergoes dynamic changes in its pattern of localization in sperm during capacitation and the acrosome reaction Autor Claire Young, Patricia Grasa, Kevin Coward, Lianne C. Davis, John Parrington

    Vydáno 2008
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  8. 8
    TPCs: Endolysosomal channels for Ca<sup>2+</sup> mobilization from acidic organelles triggered by NAADP

    TPCs: Endolysosomal channels for Ca<sup>2+</sup> mobilization from acidic organelles triggered by NAADP Autor Michael X. Zhu, Jianjie Ma, John Parrington, Antony Galione, A. Mark Evans

    Vydáno 2010
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  9. 9
    Targeting Two-Pore Channels: Current Progress and Future Challenges

    Targeting Two-Pore Channels: Current Progress and Future Challenges Autor Xuhui Jin, Yuxuan Zhang, Abeer Alharbi, Ali Hanbashi, Ali Alhoshani, John Parrington

    Vydáno 2020
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  10. 10
    Two-pore Channels Form Homo- and Heterodimers

    Two-pore Channels Form Homo- and Heterodimers Autor Katja Rietdorf, Tim M. Funnell, Margarida Ruas, Jennifer Heinemann, John Parrington, Antony Galione

    Vydáno 2011
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  11. 11
    Oocyte activation, phospholipase C zeta and human infertility

    Oocyte activation, phospholipase C zeta and human infertility Autor Junaid Kashir, Björn Heindryckx, Céline Jones, Petra De Sutter, John Parrington, Kevin Coward

    Vydáno 2010
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  12. 12
    Calcium signaling via two-pore channels: local or global, that is the question

    Calcium signaling via two-pore channels: local or global, that is the question Autor Michael X. Zhu, Jianjie Ma, John Parrington, Peter Calcraft, Antony Galione, Allan M. Evans

    Vydáno 2009
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  13. 13
    TPC2 Proteins Mediate Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP)- and Agonist-evoked Contractions of Smooth Muscle

    TPC2 Proteins Mediate Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP)- and Agonist-evoked Contractions of Smooth Muscle Autor Nezahat Tugba Durlu‐Kandilci, Margarida Ruas, Kai‐Ting Chuang, Alison F. Brading, John Parrington, Antony Galione

    Vydáno 2010
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  14. 14
    Phospholipase Cζ, the trigger of egg activation in mammals, is present in a non-mammalian species

    Phospholipase Cζ, the trigger of egg activation in mammals, is present in a non-mammalian species Autor Kevin Coward, Chris P. Ponting, H-Y Chang, Olivia Hibbitt, Peter Savolainen, Keith T. Jones, John Parrington

    Vydáno 2005
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  15. 15
    The acid test: the discovery of two-pore channels (TPCs) as NAADP-gated endolysosomal Ca2+ release channels

    The acid test: the discovery of two-pore channels (TPCs) as NAADP-gated endolysosomal Ca2+ release channels Autor Antony Galione, Allan M. Evans, Jianjie Ma, John Parrington, Abdelilah Arredouani, Xiaotong Cheng, Michael X. Zhu

    Vydáno 2009
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  16. 16
    Ca<sup>2+</sup>‐stimulated adenylyl cyclase isoform AC1 is preferentially expressed in guinea‐pig sino‐atrial node cells and modulates the <i>I</i><sub>f</sub> pacemaker current

    Ca<sup>2+</sup>‐stimulated adenylyl cyclase isoform AC1 is preferentially expressed in guinea‐pig sino‐atrial node cells and modulates the <i>I</i><sub>f</sub> pacemaker current... Autor Paul A. D. Mattick, John Parrington, Efe Odia, A Simpson, Thomas P. Collins, Derek A. Terrar

    Vydáno 2007
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  17. 17
    Characterization of two heterozygous mutations of the oocyte activation factor phospholipase C zeta (PLCζ) from an infertile man by use of minisequencing of individual sperm and expression in somatic cells

    Characterization of two heterozygous mutations of the oocyte activation factor phospholipase C zeta (PLCζ) from an infertile man by use of minisequencing of individual sperm and ex... Autor Junaid Kashir, M. Konstantinidis, Céline Jones, Björn Heindryckx, Petra De Sutter, John Parrington, Dagan Wells, Kevin Coward

    Vydáno 2012
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  18. 18
    Bidirectional Ca2+ signaling occurs between the endoplasmic reticulum and acidic organelles

    Bidirectional Ca2+ signaling occurs between the endoplasmic reticulum and acidic organelles Autor Anthony J. Morgan, Lianne C. Davis, Siegfried Wagner, Alexander M. Lewis, John Parrington, Grant C. Churchill, Antony Galione

    Vydáno 2013
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  19. 19
    Photoaffinity Labeling of High Affinity Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP)-Binding Proteins in Sea Urchin Egg

    Photoaffinity Labeling of High Affinity Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP)-Binding Proteins in Sea Urchin Egg Autor Timothy F. Walseth, Yaping Lin-Moshier, Pooja Jain, Margarida Ruas, John Parrington, Antony Galione, Jonathan S. Marchant, James T. Slama

    Vydáno 2011
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  20. 20
    Expression of Inositol 1,4,5-Trisphosphate Receptors in Mouse Oocytes and Early Embryos: The Type I Isoform Is Upregulated in Oocytes and Downregulated after Fertilization

    Expression of Inositol 1,4,5-Trisphosphate Receptors in Mouse Oocytes and Early Embryos: The Type I Isoform Is Upregulated in Oocytes and Downregulated after Fertilization Autor John Parrington, Sophie Brind, Humbert De Smedt, Ratthi Gangeswaran, F. Anthony Lai, Richard J.H. Wojcikiewicz, John Carroll

    Vydáno 1998
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