खोज परिणाम - John K. Eaton

  • प्रदर्शित 1 - 11 परिणाम 11
परिणाम को परिष्कृत करें
  1. 1
    Diacylfuroxans Are Masked Nitrile Oxides That Inhibit GPX4 Covalently

    Diacylfuroxans Are Masked Nitrile Oxides That Inhibit GPX4 Covalently द्वारा John K. Eaton, Richard A. Ruberto, Anneke Kramm, Vasanthi S. Viswanathan, Stuart L. Schreiber

    प्रकाशित 2019
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    Artigo
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  2. 2
    Structure–activity relationships of GPX4 inhibitor warheads

    Structure–activity relationships of GPX4 inhibitor warheads द्वारा John K. Eaton, Laura Furst, Luke L. Cai, Vasanthi S. Viswanathan, Stuart L. Schreiber

    प्रकाशित 2020
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  3. 3
    Cytochrome P450 oxidoreductase contributes to phospholipid peroxidation in ferroptosis

    Cytochrome P450 oxidoreductase contributes to phospholipid peroxidation in ferroptosis द्वारा Yilong Zou, Haoxin Li, Emily Graham, Amy Deik, John K. Eaton, Wenyu Wang, Gerardo Sandoval-Gomez, Clary B. Clish, John G. Doench, Stuart L. Schreiber

    प्रकाशित 2020
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  4. 4
    Crystal structures of the selenoprotein glutathione peroxidase 4 in its apo form and in complex with the covalently bound inhibitor ML162

    Crystal structures of the selenoprotein glutathione peroxidase 4 in its apo form and in complex with the covalently bound inhibitor ML162 द्वारा Dieter Moosmayer, A. Hilpmann, Jutta Hoffmann, Lennart Schnirch, Katja Zimmermann, Volker Badock, Laura Furst, John K. Eaton, Vasanthi S. Viswanathan, Stuart L. Schreiber, Stefan Gradl, R.C. Hillig

    प्रकाशित 2021
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  5. 5
    Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition

    Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition द्वारा Matthew J. Hangauer, Vasanthi S. Viswanathan, Matthew J. Ryan, Dhruv Bole, John K. Eaton, Alexandre Matov, Jacqueline Galeas, Harshil Dhruv, Michael E. Berens, Stuart L. Schreiber, Frank McCormick, Michael T. McManus

    प्रकाशित 2017
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  6. 6
    Copper induces cell death by targeting lipoylated TCA cycle proteins

    Copper induces cell death by targeting lipoylated TCA cycle proteins द्वारा Peter Tsvetkov, Shannon Coy, Boryana Petrova, Margaret Dreishpoon, Ana Verma, Mai Abdusamad, Jordan Rossen, Lena Joesch-Cohen, Ranad Humeidi, Ryan D. Spangler, John K. Eaton, Evgeni M. Frenkel, Mustafa Kocak, Steven M. Corsello, Svetlana Lutsenko, Naama Kanarek, Sandro Santagata, Todd R. Golub

    प्रकाशित 2022
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  7. 7
    A Compendium of Genetic Modifiers of Mitochondrial Dysfunction Reveals Intra-organelle Buffering

    A Compendium of Genetic Modifiers of Mitochondrial Dysfunction Reveals Intra-organelle Buffering द्वारा Tsz‐Leung To, Alejandro M. Cuadros, Hardik Shah, Wendy H.W. Hung, Li Yang, Sharon H. Kim, Daniel H. F. Rubin, Ryan H. Boe, Sneha Rath, John K. Eaton, Federica Piccioni, Amy Goodale, Zohra Kalani, John G. Doench, David E. Root, Stuart L. Schreiber, Scott B. Vafai, Vamsi K. Mootha

    प्रकाशित 2019
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  8. 8
    A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis

    A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis द्वारा Yilong Zou, Michael J. Palte, Amy Deik, Haoxin Li, John K. Eaton, Wenyu Wang, Yuen‐Yi Tseng, Rebecca Deasy, Maria Kost‐Alimova, Vlado Dančík, Elizaveta S. Leshchiner, Vasanthi S. Viswanathan, Sabina Signoretti, Toni K. Choueiri, Jesse S. Boehm, Bridget K. Wagner, John G. Doench, Clary B. Clish, Paul A. Clemons, Stuart L. Schreiber

    प्रकाशित 2019
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  9. 9
    Plasticity of ether lipids promotes ferroptosis susceptibility and evasion

    Plasticity of ether lipids promotes ferroptosis susceptibility and evasion द्वारा Yilong Zou, Whitney S. Henry, Emily L. Ricq, Emily Graham, Vaishnavi V. Phadnis, Pema Maretich, Sateja Paradkar, Natalie Boehnke, Amy Deik, Ferenc Reinhardt, John K. Eaton, Bryan Ferguson, Wenyu Wang, Joshua Fairman, Heather R. Keys, Vlado Dančík, Clary B. Clish, Paul A. Clemons, Paula T. Hammond, Laurie A. Boyer, Robert A. Weinberg, Stuart L. Schreiber

    प्रकाशित 2020
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  10. 10
    Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles

    Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles द्वारा John K. Eaton, Laura Furst, Richard A. Ruberto, Dieter Moosmayer, A. Hilpmann, Matthew J. Ryan, Katja Zimmermann, Luke L. Cai, Michael Niehues, Volker Badock, Anneke Kramm, Sixun Chen, R.C. Hillig, Paul A. Clemons, Stefan Gradl, Claire Montagnon, Kiel E. Lazarski, Sven Christian, Besnik Bajrami, Roland Neuhaus, Ashley Eheim, Vasanthi S. Viswanathan, Stuart L. Schreiber

    प्रकाशित 2020
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  11. 11
    Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

    Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway द्वारा Vasanthi S. Viswanathan, Matthew J. Ryan, Harshil Dhruv, Shubhroz Gill, Ossia M. Eichhoff, Brinton Seashore‐Ludlow, Samuel D. Kaffenberger, John K. Eaton, Kaoru Shimada, Andrew J. Aguirre, Srinivas R. Viswanathan, Shrikanta Chattopadhyay, Pablo Tamayo, Wan Seok Yang, Matthew G. Rees, Sixun Chen, Žarko Bošković, Sarah Javaid, Cherrie Huang, Xiaoyun Wu, Yuen-Yi Tseng, Elisabeth Roider, Dong Gao, James M. Cleary, Brian M. Wolpin, Jill P. Mesirov, Daniel A. Haber, Jeffrey A. Engelman, Jesse S. Boehm, Joanne Kotz, Cindy Hon, Yu Chen, William C. Hahn, Mitchell P. Levesque, John G. Doench, Michael E. Berens, Alykhan F. Shamji, Paul A. Clemons, Brent R. Stockwell, Stuart L. Schreiber

    प्रकाशित 2017
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