Search Results - John Heap

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  1. 1
    Stringency of Synthetic Promoter Sequences in <i>Clostridium</i> Revealed and Circumvented by Tuning Promoter Library Mutation Rates

    Stringency of Synthetic Promoter Sequences in <i>Clostridium</i> Revealed and Circumvented by Tuning Promoter Library Mutation Rates by Paweł M. Mordaka, John Heap

    Published 2018
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  2. 2
    The diverse sporulation characteristics of Clostridium difficile clinical isolates are not associated with type

    The diverse sporulation characteristics of Clostridium difficile clinical isolates are not associated with type by D.A. BURNS, John Heap, Nigel P. Minton

    Published 2010
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  3. 3
    SleC Is Essential for Germination of <i>Clostridium difficile</i> Spores in Nutrient-Rich Medium Supplemented with the Bile Salt Taurocholate

    SleC Is Essential for Germination of <i>Clostridium difficile</i> Spores in Nutrient-Rich Medium Supplemented with the Bile Salt Taurocholate by D.A. BURNS, John Heap, Nigel P. Minton

    Published 2009
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  4. 4
    Start-Stop Assembly: a functionally scarless DNA assembly system optimized for metabolic engineering

    Start-Stop Assembly: a functionally scarless DNA assembly system optimized for metabolic engineering by George M. Taylor, Paweł M. Mordaka, John Heap

    Published 2018
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  5. 5
    A primer to directed evolution: current methodologies and future directions

    A primer to directed evolution: current methodologies and future directions by Lara Sellés Vidal, Mark Isalan, John Heap, Rodrigo Ledesma‐Amaro

    Published 2023
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  6. 6
    Precise Manipulation of the Clostridium difficile Chromosome Reveals a Lack of Association between the <i>tcdC</i> Genotype and Toxin Production

    Precise Manipulation of the Clostridium difficile Chromosome Reveals a Lack of Association between the <i>tcdC</i> Genotype and Toxin Production by Stephen T. Cartman, Michelle L. Kelly, Daniela Heeg, John Heap, Nigel P. Minton

    Published 2012
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  7. 7
    ClosTron-Mediated Engineering of Clostridium

    ClosTron-Mediated Engineering of Clostridium by Sarah A. Kuehne, John Heap, Clare Cooksley, Stephen T. Cartman, Nigel P. Minton

    Published 2011
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  8. 8
    A Rhamnose-Inducible System for Precise and Temporal Control of Gene Expression in Cyanobacteria

    A Rhamnose-Inducible System for Precise and Temporal Control of Gene Expression in Cyanobacteria by Ciarán L. Kelly, George M. Taylor, Andrew Hitchcock, Antonio Torres-Méndez, John Heap

    Published 2018
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  9. 9
    Extracting Self-Reported COVID-19 Symptom Tweets and Twitter Movement Mobility Origin/Destination Matrices to Inform Disease Models

    Extracting Self-Reported COVID-19 Symptom Tweets and Twitter Movement Mobility Origin/Destination Matrices to Inform Disease Models by Conor Rosato, Robert Moore, Matthew Carter, John Heap, John Harris, José Storópoli, Simon Maskell

    Published 2023
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  10. 10
    The role of toxin A and toxin B in Clostridium difficile infection

    The role of toxin A and toxin B in Clostridium difficile infection by Sarah A. Kuehne, Stephen T. Cartman, John Heap, Michelle L. Kelly, Alan Cockayne, Nigel P. Minton

    Published 2010
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  11. 11
    Mutant generation by allelic exchange and genome resequencing of the biobutanol organism Clostridium acetobutylicum ATCC 824

    Mutant generation by allelic exchange and genome resequencing of the biobutanol organism Clostridium acetobutylicum ATCC 824 by Muhammad Ehsaan, Wouter Kuit, Ying Zhang, Stephen T. Cartman, John Heap, Klaus Winzer, Nigel P. Minton

    Published 2016
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  12. 12
    Integration of DNA into bacterial chromosomes from plasmids without a counter-selection marker

    Integration of DNA into bacterial chromosomes from plasmids without a counter-selection marker by John Heap, Muhammad Ehsaan, Clare Cooksley, Yen-Kuan Ng, Stephen T. Cartman, Klaus Winzer, Nigel P. Minton

    Published 2012
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  13. 13
    Synthetic negative feedback circuits using engineered small RNAs

    Synthetic negative feedback circuits using engineered small RNAs by Ciarán L. Kelly, Andreas W. K. Harris, Harrison Steel, Edward J. Hancock, John Heap, Antonis Papachristodoulou

    Published 2018
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  14. 14
    Modular Combinatorial DNA Assembly of Group B Streptococcus Capsular Polysaccharide Biosynthesis Pathways to Expediate the Production of Novel Glycoconjugate Vaccines

    Modular Combinatorial DNA Assembly of Group B Streptococcus Capsular Polysaccharide Biosynthesis Pathways to Expediate the Production of Novel Glycoconjugate Vaccines by Mark A. Harrison, Elizabeth Atkins, Alexandra Faulds‐Pain, John Heap, Brendan W. Wren, Ian J. Passmore

    Published 2025
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  15. 15
    Multiple orphan histidine kinases interact directly with Spo0A to control the initiation of endospore formation in <i>Clostridium acetobutylicum</i>

    Multiple orphan histidine kinases interact directly with Spo0A to control the initiation of endospore formation in <i>Clostridium acetobutylicum</i> by Elisabeth Steiner, Angel E. Dago, Danielle I. Young, John Heap, Nigel P. Minton, James A. Hoch, Michael Young

    Published 2011
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  16. 16
    Spores of <i>Clostridium</i> engineered for clinical efficacy and safety cause regression and cure of tumors <i>in vivo</i>

    Spores of <i>Clostridium</i> engineered for clinical efficacy and safety cause regression and cure of tumors <i>in vivo</i> by John Heap, Jan Theys, Muhammad Ehsaan, Aleksandra M. Kubiak, Ludwig J. Dubois, Kim Paesmans, Lieve Van Mellaert, Richard J. Knox, Sarah A. Kuehne, Philippe Lambin, Nigel P. Minton

    Published 2014
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  17. 17
    Synthetic Chemical Inducers and Genetic Decoupling Enable Orthogonal Control of the <i>rhaBAD</i> Promoter

    Synthetic Chemical Inducers and Genetic Decoupling Enable Orthogonal Control of the <i>rhaBAD</i> Promoter by Ciarán L. Kelly, Zilei Liu, Akihide Yoshihara, Sarah F. Jenkinson, Mark R. Wormald, José M. Otero, Amalia M. Estévez, Atsushi Kato, Mikkel H. S. Marqvorsen, George W. J. Fleet, Ramón J. Estévez, Ken Izumori, John Heap

    Published 2016
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