Resultados de búsqueda - John D. Shaughnessy

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  1. 1
    The molecular characterization and clinical management of multiple myeloma in the post-genome era

    The molecular characterization and clinical management of multiple myeloma in the post-genome era por Yiming Zhou, Bart Barlogie, John D. Shaughnessy

    Publicado 2009
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  2. 2
    Wnt3a signaling within bone inhibits multiple myeloma bone disease and tumor growth

    Wnt3a signaling within bone inhibits multiple myeloma bone disease and tumor growth por Ya‐Wei Qiang, John D. Shaughnessy, Shmuel Yaccoby

    Publicado 2008
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  3. 3
    A subset of multiple myeloma harboring the t(4;14)(p16;q32) translocation lacks FGFR3 expression but maintains anIGH/MMSET fusion transcript

    A subset of multiple myeloma harboring the t(4;14)(p16;q32) translocation lacks FGFR3 expression but maintains anIGH/MMSET fusion transcript por Madhumita Santra, Fenghuang Zhan, Erming Tian, Bart Barlogie, John D. Shaughnessy

    Publicado 2003
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  4. 4
    High-risk myeloma: a gene expression–based risk-stratification model for newly diagnosed multiple myeloma treated with high-dose therapy is predictive of outcome in relapsed disease treated with single-agent bortezomib or high-dose dexamethasone

    High-risk myeloma: a gene expression–based risk-stratification model for newly diagnosed multiple myeloma treated with high-dose therapy is predictive of outcome in relapsed diseas... por Fenghuang Zhan, Bart Barlogie, George Mulligan, John D. Shaughnessy, Barbara M. Bryant

    Publicado 2008
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  5. 5
    Developing and Validating Continuous Genomic Signatures in Randomized Clinical Trials for Predictive Medicine

    Developing and Validating Continuous Genomic Signatures in Randomized Clinical Trials for Predictive Medicine por Shigeyuki Matsui, Richard Simon, Pingping Qu, John D. Shaughnessy, Bart Barlogie, John Crowley

    Publicado 2012
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  6. 6
    Antibody-based inhibition of DKK1 suppresses tumor-induced bone resorption and multiple myeloma growth in vivo

    Antibody-based inhibition of DKK1 suppresses tumor-induced bone resorption and multiple myeloma growth in vivo por Shmuel Yaccoby, Wen Ling, Fenghuang Zhan, Ronald C. Walker, Bart Barlogie, John D. Shaughnessy

    Publicado 2006
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  7. 7
    The ephrinB2/EphB4 axis is dysregulated in osteoprogenitors from myeloma patients and its activation affects myeloma bone disease and tumor growth

    The ephrinB2/EphB4 axis is dysregulated in osteoprogenitors from myeloma patients and its activation affects myeloma bone disease and tumor growth por Angela Pennisi, Wen Ling, Xin Li, Sharmin Khan, John D. Shaughnessy, Bart Barlogie, Shmuel Yaccoby

    Publicado 2009
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  8. 8
    Characterization of Wnt/β-catenin signalling in osteoclasts in multiple myeloma

    Characterization of Wnt/β-catenin signalling in osteoclasts in multiple myeloma por Ya‐Wei Qiang, Yu Chen, Nathan Brown, Bo Hu, Joshua Epstein, Bart Barlogie, John D. Shaughnessy

    Publicado 2009
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  9. 9
    Atacicept (TACI-Ig) inhibits growth of TACIhigh primary myeloma cells in SCID-hu mice and in coculture with osteoclasts

    Atacicept (TACI-Ig) inhibits growth of TACIhigh primary myeloma cells in SCID-hu mice and in coculture with osteoclasts por Shmuel Yaccoby, Angela Pennisi, X Li, Stacey R. Dillon, Fenghuang Zhan, Bart Barlogie, John D. Shaughnessy

    Publicado 2007
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  10. 10
    The Role of the Wnt-Signaling Antagonist DKK1 in the Development of Osteolytic Lesions in Multiple Myeloma

    The Role of the Wnt-Signaling Antagonist DKK1 in the Development of Osteolytic Lesions in Multiple Myeloma por Erming Tian, Fenghuang Zhan, Ronald C. Walker, Erik Rasmussen, Yupo Ma, Bart Barlogie, John D. Shaughnessy

    Publicado 2003
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  11. 11
    Cyclin D dysregulation: an early and unifying pathogenic event in multiple myeloma

    Cyclin D dysregulation: an early and unifying pathogenic event in multiple myeloma por P. Leif Bergsagel, W. Michael Kuehl, Fenghuang Zhan, Jeffrey R. Sawyer, Bart Barlogie, John D. Shaughnessy

    Publicado 2005
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  12. 12
    Bortezomib induces osteoblast differentiation via Wnt-independent activation of β-catenin/TCF signaling

    Bortezomib induces osteoblast differentiation via Wnt-independent activation of β-catenin/TCF signaling por Ya‐Wei Qiang, Bo Hu, Yu Chen, Ying Zhong, Bingyin Shi, Bart Barlogie, John D. Shaughnessy

    Publicado 2009
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  13. 13
    Treatment of multiple myeloma

    Treatment of multiple myeloma por Bart Barlogie, John D. Shaughnessy, Guido Tricot, Joth Jacobson, Maurizio Zangari, Elias Anaissie, Ron Walker, John Crowley

    Publicado 2003
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  14. 14
    Myeloma-derived Dickkopf-1 disrupts Wnt-regulated osteoprotegerin and RANKL production by osteoblasts: a potential mechanism underlying osteolytic bone lesions in multiple myeloma

    Myeloma-derived Dickkopf-1 disrupts Wnt-regulated osteoprotegerin and RANKL production by osteoblasts: a potential mechanism underlying osteolytic bone lesions in multiple myeloma por Ya‐Wei Qiang, Yu Chen, Owen Stephens, Nathan Brown, Bangzheng Chen, Joshua Epstein, Bart Barlogie, John D. Shaughnessy

    Publicado 2008
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  15. 15
    CKS1B, overexpressed in aggressive disease, regulates multiple myeloma growth and survival through SKP2- and p27Kip1-dependent and -independent mechanisms

    CKS1B, overexpressed in aggressive disease, regulates multiple myeloma growth and survival through SKP2- and p27Kip1-dependent and -independent mechanisms por Fenghuang Zhan, Simona Colla, Xiaosong Wu, Bangzheng Chen, Peter Stewart, W. Michael Kuehl, Bart Barlogie, John D. Shaughnessy

    Publicado 2007
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  16. 16
    Genomic instability in multiple myeloma: Evidence for jumping segmental duplications of chromosome arm 1q

    Genomic instability in multiple myeloma: Evidence for jumping segmental duplications of chromosome arm 1q por Jeffrey R. Sawyer, Guido Tricot, Janet L. Lukacs, Regina Lichti Binz, Erming Tian, Bart Barlogie, John D. Shaughnessy

    Publicado 2004
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  17. 17
    Diagnostic Usefulness and Prognostic Impact of CD200 Expression in Lymphoid Malignancies and Plasma Cell Myeloma

    Diagnostic Usefulness and Prognostic Impact of CD200 Expression in Lymphoid Malignancies and Plasma Cell Myeloma por Daisy Alapat, Jean M. Coviello‐Malle, Rebecca Owens, Pingping Qu, Bart Barlogie, John D. Shaughnessy, Robert B. Lorsbach

    Publicado 2011
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  18. 18
    The role of Dickkopf-1 in bone development, homeostasis, and disease

    The role of Dickkopf-1 in bone development, homeostasis, and disease por Joseph J. Pinzone, Brett M. Hall, Nanda K. Thudi, Martin Vonau, Ya‐Wei Qiang, Thomas J. Rosol, John D. Shaughnessy

    Publicado 2008
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  19. 19
    Secondary genomic rearrangements involving immunoglobulin or MYC loci show similar prevalences in hyperdiploid and nonhyperdiploid myeloma tumors

    Secondary genomic rearrangements involving immunoglobulin or MYC loci show similar prevalences in hyperdiploid and nonhyperdiploid myeloma tumors por Ana Gabrea, Marialuisa Martelli, Ying Qi, Anna V. Roschke, Bart Barlogie, John D. Shaughnessy, Jeffrey R. Sawyer, W. Michael Kuehl

    Publicado 2008
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  20. 20
    Absence Epilepsy in Tottering Mutant Mice Is Associated with Calcium Channel Defects

    Absence Epilepsy in Tottering Mutant Mice Is Associated with Calcium Channel Defects por Colin Fletcher, Cathleen Lutz, T. Norene O’Sullivan, John D. Shaughnessy, Richard Hawkes, Wayne N. Frankel, Neal G. Copeland, Nancy A. Jenkins

    Publicado 1996
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