Resultados da pesquisa - John D. Norris

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  1. 1
    Identification of a Negative Regulatory Surface within Estrogen Receptor α Provides Evidence in Support of a Role for Corepressors in Regulating Cellular Responses to Agonists and Antagonists

    Identification of a Negative Regulatory Surface within Estrogen Receptor α Provides Evidence in Support of a Role for Corepressors in Regulating Cellular Responses to Agonists and... Por Huey-Jing Huang, John D. Norris, Donald P. McDonnell

    Publicado em 2002
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  2. 2
    Oral Selective Estrogen Receptor Downregulators (SERDs), a Breakthrough Endocrine Therapy for Breast Cancer

    Oral Selective Estrogen Receptor Downregulators (SERDs), a Breakthrough Endocrine Therapy for Breast Cancer Por Donald P. McDonnell, Suzanne E. Wardell, John D. Norris

    Publicado em 2015
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  3. 3
    Enhancement of Estrogen Receptor Transcriptional Activity by the Coactivator GRIP-1 Highlights the Role of Activation Function 2 in Determining Estrogen Receptor Pharmacology

    Enhancement of Estrogen Receptor Transcriptional Activity by the Coactivator GRIP-1 Highlights the Role of Activation Function 2 in Determining Estrogen Receptor Pharmacology Por John D. Norris, Daju Fan, Michael R. Stallcup, Donald P. McDonnell

    Publicado em 1998
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  4. 4
    Identification of a Third Autonomous Activation Domain within the Human Estrogen Receptor

    Identification of a Third Autonomous Activation Domain within the Human Estrogen Receptor Por John D. Norris, Daju Fan, Sandra A. Kerner, Donald P. McDonnell

    Publicado em 1997
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  5. 5
    A Negative Coregulator for the Human ER

    A Negative Coregulator for the Human ER Por John D. Norris, Daju Fan, Andrea B. Sherk, Donald P. McDonnell

    Publicado em 2002
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  6. 6
    Modulation of Estrogen Receptor-α Transcriptional Activity by the Coactivator PGC-1

    Modulation of Estrogen Receptor-α Transcriptional Activity by the Coactivator PGC-1 Por Irina Y. Tcherepanova, Pere Puigserver, John D. Norris, Bruce M. Spiegelman, Donald P. McDonnell

    Publicado em 2000
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  7. 7
    The Nuclear Corepressors NCoR and SMRT Are Key Regulators of Both Ligand- and 8-Bromo-Cyclic AMP-Dependent Transcriptional Activity of the Human Progesterone Receptor

    The Nuclear Corepressors NCoR and SMRT Are Key Regulators of Both Ligand- and 8-Bromo-Cyclic AMP-Dependent Transcriptional Activity of the Human Progesterone Receptor Por Brandee Wagner, John D. Norris, Trina A. Knotts, Nancy L. Weigel, Donald P. McDonnell

    Publicado em 1998
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  8. 8
    Structural Basis for an Unexpected Mode of SERM-Mediated ER Antagonism

    Structural Basis for an Unexpected Mode of SERM-Mediated ER Antagonism Por Ya-Ling Wu, Xiaojing Yang, Zhong Ren, Donald P. McDonnell, John D. Norris, Timothy M. Willson, Geoffrey L. Greene

    Publicado em 2005
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  9. 9
    Comparative Analyses of Mechanistic Differences Among Antiestrogens1

    Comparative Analyses of Mechanistic Differences Among Antiestrogens1 Por Ashini L. Wijayaratne, Susan C. Nagel, Lisa A. Paige, Dale J. Christensen, John D. Norris, Dana M. Fowlkes, Donald P. McDonnell

    Publicado em 1999
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  10. 10
    The Homeodomain Protein HOXB13 Regulates the Cellular Response to Androgens

    The Homeodomain Protein HOXB13 Regulates the Cellular Response to Androgens Por John D. Norris, Ching‐yi Chang, Bryan M. Wittmann, Rebecca Kunder, Huaxia Cui, Daju Fan, James D. Joseph, Donald P. McDonnell

    Publicado em 2009
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  11. 11
    Dissection of the LXXLL Nuclear Receptor-Coactivator Interaction Motif Using Combinatorial Peptide Libraries: Discovery of Peptide Antagonists of Estrogen Receptors α and β

    Dissection of the LXXLL Nuclear Receptor-Coactivator Interaction Motif Using Combinatorial Peptide Libraries: Discovery of Peptide Antagonists of Estrogen Receptors α and β Por Ching‐yi Chang, John D. Norris, Hanne Grøn, Lisa A. Paige, Paul T. Hamilton, Daniel J. Kenan, Dana M. Fowlkes, Donald P. McDonnell

    Publicado em 1999
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  12. 12
    Induction of Krüppel-Like Factor 5 Expression by Androgens Results in Increased CXCR4-Dependent Migration of Prostate Cancer Cells<i>in Vitro</i>

    Induction of Krüppel-Like Factor 5 Expression by Androgens Results in Increased CXCR4-Dependent Migration of Prostate Cancer Cells<i>in Vitro</i> Por Daniel E. Frigo, Andrea B. Sherk, Bryan M. Wittmann, John D. Norris, Qianben Wang, James D. Joseph, Aidan Toner, Myles Brown, Donald P. McDonnell

    Publicado em 2009
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  13. 13
    Identification of a New Subclass of Alu DNA Repeats Which Can Function as Estrogen Receptor-dependent Transcriptional Enhancers

    Identification of a New Subclass of Alu DNA Repeats Which Can Function as Estrogen Receptor-dependent Transcriptional Enhancers Por John D. Norris, Daju Fan, Claudina Alemán, Jeffrey R. Marks, P. Andrew Futreal, Roger W. Wiseman, J. Dirk Iglehart, Prescott L. Deininger, Donald P. McDonnell

    Publicado em 1995
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  14. 14
    Obesity, Cholesterol Metabolism, and Breast Cancer Pathogenesis

    Obesity, Cholesterol Metabolism, and Breast Cancer Pathogenesis Por Donald P. McDonnell, Sung Hee Park, Matthew T. Goulet, Jeff S. Jasper, Suzanne E. Wardell, Ching‐yi Chang, John D. Norris, John R. Guyton, Erik R. Nelson

    Publicado em 2014
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  15. 15
    MMTV-PyMT and Derived Met-1 Mouse Mammary Tumor Cells as Models for Studying the Role of the Androgen Receptor in Triple-Negative Breast Cancer Progression

    MMTV-PyMT and Derived Met-1 Mouse Mammary Tumor Cells as Models for Studying the Role of the Androgen Receptor in Triple-Negative Breast Cancer Progression Por Jessica L. Christenson, Kiel T. Carson Butterfield, Nicole S. Spoelstra, John D. Norris, J.S. Josan, Julie A. Pollock, Donald P. McDonnell, Benita S. Katzenellenbogen, John A. Katzenellenbogen, Jennifer K. Richer

    Publicado em 2017
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  16. 16
    Pharmacokinetic and pharmacodynamic analysis of fulvestrant in preclinical models of breast cancer to assess the importance of its estrogen receptor-α degrader activity in antitumor efficacy

    Pharmacokinetic and pharmacodynamic analysis of fulvestrant in preclinical models of breast cancer to assess the importance of its estrogen receptor-α degrader activity in antitumo... Por Suzanne E. Wardell, Alexander P. Yllanes, Christina Chao, Yeeun Bae, Kaitlyn J. Andreano, Taylor K. Desautels, Kendall A. Heetderks, Jeremy T. Blitzer, John D. Norris, Donald P. McDonnell

    Publicado em 2019
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  17. 17
    Estrogen receptor (ER) modulators each induce distinct conformational changes in ER α and ER β

    Estrogen receptor (ER) modulators each induce distinct conformational changes in ER α and ER β Por Lisa A. Paige, Dale J. Christensen, Hanne Grøn, John D. Norris, Elizabeth B. Gottlin, Karen Padilla, Ching‐yi Chang, Lawrence M. Ballas, Paul T. Hamilton, Donald P. McDonnell, Dana M. Fowlkes

    Publicado em 1999
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  18. 18
    Development of a Small-Molecule Serum- and Glucocorticoid-Regulated Kinase-1 Antagonist and Its Evaluation as a Prostate Cancer Therapeutic

    Development of a Small-Molecule Serum- and Glucocorticoid-Regulated Kinase-1 Antagonist and Its Evaluation as a Prostate Cancer Therapeutic Por Andrea B. Sherk, Daniel E. Frigo, Christine G. Schnackenberg, Jeffrey D. Bray, Nicholas J. Laping, Walter Trizna, Marlys Hammond, Jaclyn R. Patterson, Scott K. Thompson, Dmitri Kazmin, John D. Norris, Donald P. McDonnell

    Publicado em 2008
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  19. 19
    Small‐Molecule‐Mediated Degradation of the Androgen Receptor through Hydrophobic Tagging

    Small‐Molecule‐Mediated Degradation of the Androgen Receptor through Hydrophobic Tagging Por Jeffrey L. Gustafson, Taavi K. Neklesa, Carly S. Cox, Anke G. Roth, Dennis L. Buckley, Hyun Seop Tae, Thomas B. Sundberg, David B. Stagg, John Hines, Donald P. McDonnell, John D. Norris, Craig M. Crews

    Publicado em 2015
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  20. 20
    Dissection of the Molecular Mechanism of Action of GW5638, a Novel Estrogen Receptor Ligand, Provides Insights into the Role of Estrogen Receptor in Bone*

    Dissection of the Molecular Mechanism of Action of GW5638, a Novel Estrogen Receptor Ligand, Provides Insights into the Role of Estrogen Receptor in Bone* Por Timothy M. Willson, John D. Norris, B L Wagner, I. Asplin, Philip G. Baer, H. Roger Brown, Stacey A. Jones, Brad R. Henke, Howard R. Sauls, Steven G. Wolfe, David C. Morris, Donald P. McDonnell

    Publicado em 1997
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