Rezultati pretrage - Johannes C. Melms

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  1. 1
    Immunosuppressive Myeloid Cells Induce Nitric Oxide–Dependent DNA Damage and p53 Pathway Activation in CD8+ T Cells

    Immunosuppressive Myeloid Cells Induce Nitric Oxide–Dependent DNA Damage and p53 Pathway Activation in CD8+ T Cells od Adam N.R. Cartwright, Shengbao Suo, S Badrinath, Sushil Kumar, Johannes C. Melms, Adrienne Luoma, Archis Bagati, Assieh Saadatpour, Benjamin Izar, Guo‐Cheng Yuan, Kai W. Wucherpfennig

    Izdano 2021
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  2. 2
    Protective efficacy of phosphodiesterase-1 inhibition against alpha-synuclein toxicity revealed by compound screening in LUHMES cells

    Protective efficacy of phosphodiesterase-1 inhibition against alpha-synuclein toxicity revealed by compound screening in LUHMES cells od Matthias Höllerhage, Claudia Moebius, Johannes C. Melms, Wei‐Hua Chiu, Joachim Goebel, Tasnim Chakroun, Thomas Koeglsperger, Wolfgang H. Oertel, Thomas W. Rösler, Marc Bickle, Günter U. Höglinger

    Izdano 2017
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  3. 3
    Fingolimod induces neuroprotective factors in human astrocytes

    Fingolimod induces neuroprotective factors in human astrocytes od Franziska Hoffmann, Johann Hofereiter, Heike Rübsamen, Johannes C. Melms, Sigrid C. Schwarz, Hans von Faber, Peter Weber, Benno Pütz, Verena Loleit, Frank Weber, Reinhard Hohlfeld, Edgar Meinl, Markus Krumbholz

    Izdano 2015
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  4. 4
    Histone acetylation of bile acid transporter genes plays a critical role in cirrhosis

    Histone acetylation of bile acid transporter genes plays a critical role in cirrhosis od Amanda Garrido, Eunjeong Kim, Ana Teijeiro, Paula Sánchez Sánchez, Rosa Gallo, Ajay Nair, María Matamala Montoya, Cristian Perna, Guillermo P. Vicent, Javier Muñoz, Ramón Campos‐Olivas, Johannes C. Melms, Benjamin Izar, Robert F. Schwabe, Nabil Djouder

    Izdano 2021
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  5. 5
    Contribution of Trp63CreERT2-labeled cells to alveolar regeneration is independent of tuft cells

    Contribution of Trp63CreERT2-labeled cells to alveolar regeneration is independent of tuft cells od Huachao Huang, Yinshan Fang, Ming Jiang, Yihan Zhang, Jana Biermann, Johannes C. Melms, Jennifer Danielsson, Ying Yang, Li Qiang, Jia Liu, Yiwu Zhou, Manli Wang, Zhìhóng Hú, Timothy C. Wang, Anjali Saqi, Jie Sun, Ichiro Matsumoto, Wellington V. Cardoso, Charles W. Emala, Jian Zhu, Benjamin Izar, Hongmei Mou, Jianwen Que

    Izdano 2022
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  6. 6
    Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion

    Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion od Chris J. Frangieh, Johannes C. Melms, Pratiksha I. Thakore, Kathryn Geiger‐Schuller, Patricia Ho, Adrienne Luoma, Brian Cleary, Livnat Jerby‐Arnon, Shruti Malu, Michael S. Cuoco, Maryann Zhao, Casey R. Ager, Meri Rogava, Lila Hovey, Asaf Rotem, Chantale Bernatchez, Kai W. Wucherpfennig, Bruce E. Johnson, Orit Rozenblatt–Rosen, Dirk Schadendorf, Aviv Regev, Benjamin Izar

    Izdano 2021
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  7. 7
    Neoadjuvant durvalumab plus radiation versus durvalumab alone in stages I–III non-small cell lung cancer: survival outcomes and molecular correlates of a randomized phase II trial

    Neoadjuvant durvalumab plus radiation versus durvalumab alone in stages I–III non-small cell lung cancer: survival outcomes and molecular correlates of a randomized phase II trial... od Nasser K. Altorki, Zachary Walsh, Johannes C. Melms, Jeffery L. Port, Benjamin E. Lee, Abu Nasar, C Spinelli, Lindsay Caprio, Meri Rogava, Patricia Ho, Paul J. Christos, Ashish Saxena, Olivier Elemento, Bhavneet Bhinder, Casey R. Ager, Amit Dipak Amin, Nicholas J Sanfilippo, Vivek Mittal, Alain Borczuk, Silvia C. Formenti, Benjamin Izar, Timothy E. McGraw

    Izdano 2023
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  8. 8
    Multimodal single-cell and whole-genome sequencing of small, frozen clinical specimens

    Multimodal single-cell and whole-genome sequencing of small, frozen clinical specimens od Yiping Wang, Joy Linyue Fan, Johannes C. Melms, Amit Dipak Amin, Yohanna Georgis, Irving Barrera, Patricia Ho, Somnath Tagore, Gabriel Abril-Rodríguez, Siyu He, Yinuo Jin, Jana Biermann, Matan Hofree, Lindsay Caprio, Simon Berhe, Shaheer Khan, Brian S. Henick, Antoni Ribas, Evan Z. Macosko, Fei Chen, Alison M. Taylor, Gary K. Schwartz, Richard D. Carvajal, Elham Azizi, Benjamin Izar

    Izdano 2023
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  9. 9
    A single-cell landscape of high-grade serous ovarian cancer

    A single-cell landscape of high-grade serous ovarian cancer od Benjamin Izar, Itay Tirosh, Elizabeth H. Stover, Isaac Wakiro, Michael S. Cuoco, Idan Alter, Christopher Rodman, Rachel Leeson, Mei-Ju Su, Parin Shah, Marcin Iwanicki, Sarah R. Walker, Abhay Kanodia, Johannes C. Melms, Shaolin Mei, Jia‐Ren Lin, Caroline Porter, Michal Slyper, Julia Waldman, Livnat Jerby‐Arnon, Orr Ashenberg, Titus J. Brinker, Caitlin E. Mills, Meri Rogava, Sébastien Vigneau, Peter K. Sorger, Levi A. Garraway, Panagiotis A. Konstantinopoulos, Joyce F. Liu, Ursula A. Matulonis, Bruce E. Johnson, Orit Rozenblatt–Rosen, Asaf Rotem, Aviv Regev

    Izdano 2020
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  10. 10
    The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and shapes anti-tumor immunity

    The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and shapes anti-tumor immunity od Patricia Ho, Johannes C. Melms, Meri Rogava, Chris J. Frangieh, Joanna Poźniak, Shivem B. Shah, Zachary Walsh, Oleksandr Kyrysyuk, Amit Dipak Amin, Lindsay Caprio, Benjamin T. Fullerton, Rajesh K. Soni, Casey R. Ager, Jana Biermann, Yi‐Ping Wang, Mohsen Khosravi‐Maharlooei, Giorgia Zanetti, Michael Mu, Hijab Fatima, Emily K. Moore, Neil Vasan, Samuel F. Bakhoum, Steven L. Reiner, Chantale Bernatchez, Megan Sykes, Emily M. Mace, Kai W. Wucherpfennig, Dirk Schadendorf, Oliver Bechter, Parin Shah, Gary K. Schwartz, Jean‐Christophe Marine, Benjamin Izar

    Izdano 2023
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  11. 11
    Metastasis and Immune Evasion from Extracellular cGAMP Hydrolysis

    Metastasis and Immune Evasion from Extracellular cGAMP Hydrolysis od Jun Li, Mercedes A. Duran Paez, Ninjit Dhanota, Walid K. Chatila, Sarah E. Bettigole, John Kwon, Roshan K. Sriram, Matthew P. Humphries, Manuel Salto‐Tellez, Jacqueline A. James, Matthew G. Hanna, Johannes C. Melms, Sreeram Vallabhaneni, Kevin Litchfield, Ieva Usaite, Dhruva Biswas, Rohan Bareja, Hao Wei Li, M. Laura Martín, Princesca Dorsaint, Julie‐Ann Cavallo, Li Peng, Chantal Pauli, Lee Gottesdiener, Benjamin J. DiPardo, Travis J. Hollmann, Taha Merghoub, Hannah Y. Wen, Jorge S. Reis‐Filho, Nadeem Riaz, Shinsan M. Su, Anusha Kalbasi, Neil Vasan, Simon N. Powell, Jedd D. Wolchok, Olivier Elemento, Charles Swanton, Alexander N. Shoushtari, Eileen E. Parkes, Benjamin Izar, Samuel F. Bakhoum

    Izdano 2020
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  12. 12
    A molecular single-cell lung atlas of lethal COVID-19

    A molecular single-cell lung atlas of lethal COVID-19 od Johannes C. Melms, Jana Biermann, Huachao Huang, Yiping Wang, Ajay Nair, Somnath Tagore, Igor Katsyv, André F. Rendeiro, Amit Dipak Amin, Denis Schapiro, Chris J. Frangieh, Adrienne Luoma, Aveline Filliol, Yinshan Fang, Hiranmayi Ravichandran, Mariano Guardia Clausi, George A. Alba, Meri Rogava, Sean W. Chen, Patricia Ho, Daniel T. Montoro, Adam Kornberg, Arnold Han, Mathieu F. Bakhoum, Niroshana Anandasabapathy, Mayte Suárez‐Fariñas, Samuel F. Bakhoum, Yaron Bram, Alain Borczuk, Xinzheng V. Guo, Jay H. Lefkowitch, Charles C. Marboe, Stephen M. Lagana, Armando Del Portillo, Emily J. Tsai, Emmanuel Zorn, Glen S. Markowitz, Robert F. Schwabe, Robert E. Schwartz, Olivier Elemento, Anjali Saqi, Hanina Hibshoosh, Jianwen Que, Benjamin Izar

    Izdano 2021
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  13. 13
    Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation

    Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation od Meri Rogava, Tyler J. Aprati, Wei-Yu Chi, Johannes C. Melms, Clemens Hug, Stephanie H. Davis, Ethan M. Earlie, Charlie Chung, Sachin Kumar Deshmukh, Sharon Wu, George W. Sledge, Stephen Tang, Patricia Ho, Amit Dipak Amin, Lindsay Caprio, Carino Gurjao, Somnath Tagore, Bryan Ngo, Michael J. Lee, Giorgia Zanetti, Yiping Wang, Sean Chen, William Ge, Luiza Martins Nascentes Melo, Gabriele Allies, Jonas Rösler, Goeffrey T. Gibney, Oliver J. Schmitz, Megan Sykes, Rémi J. Creusot, Thomas Tüting, Dirk Schadendorf, Martin Röcken, Thomas Eigentler, Andrei Molotkov, Akiva Mintz, Samuel F. Bakhoum, Semir Beyaz, Lewis C. Cantley, Peter K. Sorger, Sven W. Meckelmann, Alpaslan Tasdogan, David Liu, Ashley M. Laughney, Benjamin Izar

    Izdano 2024
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  14. 14
    Hepatic stellate cells control liver zonation, size and functions via R-spondin 3

    Hepatic stellate cells control liver zonation, size and functions via R-spondin 3 od Atsushi Sugimoto, Yoshinobu Saito, Guanxiong Wang, Qiuyan Sun, Chuan Yin, Ki Hong Lee, Yana Geng, Presha Rajbhandari, Céline Hernandez, Marcella Steffani, Jingran Qie, Thomas Savage, Dhruv M. Goyal, Kevin C. Ray, Taruna V. Neelakantan, Deqi Yin, Johannes C. Melms, Brandon M. Lehrich, Tyler M. Yasaka, Silvia Liu, Michael Oertel, Tian Lan, Adrien Guillot, Moritz Peiseler, Aveline Filliol, Hiroaki Kanzaki, Naoto Fujiwara, Samhita Ravi, Benjamin Izar, Mario Brosch, Jochen Hampe, Helen Remotti, Josepmaria Argemí, Zhaoli Sun, Timothy J. Kendall, Yujin Hoshida, Frank Tacke, Jonathan A. Fallowfield, Storm Blockley-Powell, Rebecca A. Haeusler, Jonathan B. Steinman, Utpal B. Pajvani, Satdarshan P. Monga, Ramón Bataller, Mojgan Masoodi, Nicholas Arpaia, Youngmin A. Lee, Brent R. Stockwell, Hellmut G. Augustin, Robert F. Schwabe

    Izdano 2025
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  15. 15
    A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade

    A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade od Livnat Jerby‐Arnon, Parin Shah, Michael S. Cuoco, Christopher Rodman, Mei-Ju Su, Johannes C. Melms, Rachel Leeson, Abhay Kanodia, Shaolin Mei, Jia‐Ren Lin, Shu Wang, Bokang Rabasha, David Liu, Gao Zhang, Claire Margolais, Orr Ashenberg, Patrick A. Ott, Elizabeth I. Buchbinder, Rizwan Haq, F. Stephen Hodi, Genevieve M. Boland, Ryan J. Sullivan, Dennie T. Frederick, Benchun Miao, Tabea Moll, Keith T. Flaherty, Meenhard Herlyn, Russell W. Jenkins, Rohit Thummalapalli, Monika S. Kowalczyk, Israel Cañadas, Bastian Schilling, Adam N.R. Cartwright, Adrienne Luoma, Shruti Malu, Patrick Hwu, Chantale Bernatchez, Marie-Andrée Forget, David A. Barbie, Alex K. Shalek, Itay Tirosh, Peter K. Sorger, Kai W. Wucherpfennig, Eliezer M. Van Allen, Dirk Schadendorf, Bruce E. Johnson, Asaf Rotem, Orit Rozenblatt–Rosen, Levi A. Garraway, Charles H. Yoon, Benjamin Izar, Aviv Regev

    Izdano 2018
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  16. 16
    Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma

    Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma od Livnat Jerby‐Arnon, Cyril Neftel, Marni E. Shore, Hannah Weisman, Nathan D. Mathewson, Matthew J. McBride, Brian J. Haas, Benjamin Izar, Angela Volorio, Gaylor Boulay, Luisa Cironi, Alyssa Richman, Liliane C. Broye, Joseph M. Gurski, Christina C. Luo, Ravindra Mylvaganam, Lan Nguyễn, Shaolin Mei, Johannes C. Melms, C Georgescu, Ofir Cohen, Jorge E. Buendia-Buendia, Åsa Segerstolpe, Malika Sud, Michael S. Cuoco, Danny Labes, Simon Gritsch, Daniel R. Zollinger, Nicole Ortogero, Joseph Beechem, G. Petur Nielsen, Ivan Chebib, Tu Nguyen‐Ngoc, Michael Montemurro, Gregory M. Coté, Edwin Choy, Igor Letovanec, Stéphane Cherix, Nikhil Wagle, Peter K. Sorger, Alex B. Haynes, John T. Mullen, Ivan Stamenkovic, Miguel N. Rivera, Cigall Kadoch, Kai W. Wucherpfennig, Orit Rozenblatt–Rosen, Mario L. Suvà, Nicolò Riggi, Aviv Regev

    Izdano 2021
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  17. 17
    Dissecting the treatment-naive ecosystem of human melanoma brain metastasis

    Dissecting the treatment-naive ecosystem of human melanoma brain metastasis od Jana Biermann, Johannes C. Melms, Amit Dipak Amin, Yiping Wang, Lindsay Caprio, Alcida Karz, Somnath Tagore, Irving Barrera, Miguel A. Ibarra-Arellano, Massimo Andreatta, Benjamin T. Fullerton, Kristjan H. Gretarsson, Varun Sahu, Vaibhav S. Mangipudy, Trang Nguyen, Ajay Nair, Meri Rogava, Patricia Ho, Peter D. Koch, Matei A. Banu, Nelson Humala, Aayushi Mahajan, Zachary Walsh, Shivem B. Shah, Daniel H. Vaccaro, Blake Caldwell, Michael Mu, Florian Wünnemann, Margot Chazotte, Simon Berhe, Adrienne Luoma, Joseph Driver, Matthew Ingham, Shaheer Khan, Suthee Rapisuwon, Craig L. Slingluff, Thomas Eigentler, Martin Röcken, Richard D. Carvajal, Michael B. Atkins, Michael A. Davies, Albert S. Agustinus, Samuel F. Bakhoum, Elham Azizi, Markus D. Siegelin, Chao Lü, Santiago J. Carmona, Hanina Hibshoosh, Antoni Ribas, Peter Canoll, Jeffrey N. Bruce, Wenya Linda Bi, Praveen Agrawal, Denis Schapiro, Eva Hernando, Evan Z. Macosko, Fei Chen, Gary K. Schwartz, Benjamin Izar

    Izdano 2022
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  18. 18
    COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets

    COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets od Toni Delorey, Carly G.K. Ziegler, Graham Heimberg, Rachelly Normand, Yiming Yang, Åsa Segerstolpe, Domenic Abbondanza, Stephen J. Fleming, Ayshwarya Subramanian, Daniel T. Montoro, Karthik A. Jagadeesh, Kushal K. Dey, Pritha Sen, Michal Slyper, Yered Pita-Juárez, Devan Phillips, Jana Biermann, Zohar Bloom‐Ackermann, Nikolaos Barkas, Andrea Ganna, James Gomez, Johannes C. Melms, Igor Katsyv, Erica Normandin, Pourya Naderi Yeganeh, Yury Popov, Siddharth S. Raju, Sebastian Niezen, Linus Tsai, Katherine J. Siddle, Malika Sud, Victoria M. Tran, Shamsudheen Karuthedath Vellarikkal, Yiping Wang, Liat Amir-Zilberstein, Deepak Atri, Joseph Beechem, Olga R. Brook, Jonathan H. Chen, Prajan Divakar, Phylicia Dorceus, J Engreitz, Adam L. Essene, Donna M. Fitzgerald, Robin Fropf, Steven Gazal, Joshua Gould, John Grzyb, Tyler Harvey, Jonathan L. Hecht, Tyler Hether, Judit Jané‐Valbuena, Michael Leney-Greene, Hui Ma, Cristin McCabe, Daniel E. McLoughlin, Eric Miller, Christoph Muus, Mari Niemi, Robert F. Padera, Liuliu Pan, Deepti Pant, Carmel Pe’er, Jenna Pfiffner-Borges, Christopher J. Pinto, Jacob Plaisted, Jason Reeves, Marty Ross, Melissa A. Rudy, Erroll H. Rueckert, Michelle Siciliano, Alexander Sturm, Ellen Todres, Avinash Waghray, Sarah Warren, Shuting Zhang, Daniel R. Zollinger, Lisa A. Cosimi, Rajat M. Gupta, Nir Hacohen, Hanina Hibshoosh, Yoshihide Hayashizaki, Alkes L. Price, Jayaraj Rajagopal, Purushothama Rao Tata, Stefan Riedel, Gyöngyi Szabó, Timothy L. Tickle, Patrick T. Ellinor, Deborah T. Hung, Pardis C. Sabeti, Richard Novák, Robert Rogers, Donald E. Ingber, Z. Gordon Jiang, Dejan Juric, Mehrtash Babadi, Samouil L. Farhi, Benjamin Izar, James R. Stone

    Izdano 2021
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