Výsledky vyhledávání - Joan Montero

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  1. 1
    Why do BCL-2 inhibitors work and where should we use them in the clinic?

    Why do BCL-2 inhibitors work and where should we use them in the clinic? Autor Joan Montero, Antony Letai

    Vydáno 2017
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  2. 2
    Adapted to Survive: Targeting Cancer Cells with BH3 Mimetics

    Adapted to Survive: Targeting Cancer Cells with BH3 Mimetics Autor Joan Montero, Rizwan Haq

    Vydáno 2022
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  3. 3
    p53 regulates a non-apoptotic death induced by ROS

    p53 regulates a non-apoptotic death induced by ROS Autor Joan Montero, Chaitali Dutta, Diederik van Bodegom, David M. Weinstock, Anthony Letai

    Vydáno 2013
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  4. 4
    Cholesterol and peroxidized cardiolipin in mitochondrial membrane properties, permeabilization and cell death

    Cholesterol and peroxidized cardiolipin in mitochondrial membrane properties, permeabilization and cell death Autor Joan Montero, Montserrat Marı́, Anna Colell, Albert Morales, Gorka Basáñez, Carmen García‐Ruiz, José C. Fernández–Checa

    Vydáno 2010
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  5. 5
    BID Preferentially Activates BAK while BIM Preferentially Activates BAX, Affecting Chemotherapy Response

    BID Preferentially Activates BAK while BIM Preferentially Activates BAX, Affecting Chemotherapy Response Autor Kristopher A. Sarosiek, Xiaoke Chi, John A. Bachman, Joshua J. Sims, Joan Montero, Luv Patel, Annabelle Flanagan, David W. Andrews, Peter K. Sorger, Anthony Letai

    Vydáno 2013
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  6. 6
    Dual inhibition of MDM2 and MDM4 in virus-positive Merkel cell carcinoma enhances the p53 response

    Dual inhibition of MDM2 and MDM4 in virus-positive Merkel cell carcinoma enhances the p53 response Autor Donglim Esther Park, Jingwei Cheng, Christian Berrios, Joan Montero, Marta Cortés-Cros, Stéphane Ferretti, Reety Arora, Michelle Tillgren, Prafulla C. Gokhale, James A. DeCaprio

    Vydáno 2018
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  7. 7
    Mitochondrial Cholesterol Contributes to Chemotherapy Resistance in Hepatocellular Carcinoma

    Mitochondrial Cholesterol Contributes to Chemotherapy Resistance in Hepatocellular Carcinoma Autor Joan Montero, Albert Morales, Laura Llacuna, Josep M. Lluis, Oihana Terrones, Gorka Basáñez, Bruno Antonsson, Jesús Prìeto, Carmen García‐Ruiz, Anna Colell, José C. Fernández–Checa

    Vydáno 2008
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  8. 8
    <scp>KPT</scp>‐330 inhibitor of <scp>CRM</scp>1 (<scp>XPO</scp>1)‐mediated nuclear export has selective anti‐leukaemic activity in preclinical models of <scp>T</scp>‐cell acute lymphoblastic leukaemia and acute myeloid leukaemia

    <scp>KPT</scp>‐330 inhibitor of <scp>CRM</scp>1 (<scp>XPO</scp>1)‐mediated nuclear export has selective anti‐leukaemic activity in preclinical models of <scp>T</scp>‐cell acute lym... Autor Julia Etchin, Takaomi Sanda, Marc R. Mansour, Alex Kentsis, Joan Montero, Bonnie Le, Amanda L. Christie, Dilara McCauley, Scott J. Rodig, Michael Kauffman, Sharon Shacham, Richard M. Stone, Anthony Letai, Andrew L. Kung, A. Thomas Look

    Vydáno 2013
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  9. 9
    Destabilization of NOXA mRNA as a common resistance mechanism to targeted therapies

    Destabilization of NOXA mRNA as a common resistance mechanism to targeted therapies Autor Joan Montero, Cécile Gstalder, Daniel J. Kim, Dorota Sadowicz, Wayne Miles, Michael P. Manos, Justin Cidado, J. Paul Secrist, Adriana E. Tron, Keith T. Flaherty, F. Stephen Hodi, Charles H. Yoon, Anthony Letai, David E. Fisher, Rizwan Haq

    Vydáno 2019
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  10. 10
    Targeted apoptosis of myofibroblasts with the BH3 mimetic ABT-263 reverses established fibrosis

    Targeted apoptosis of myofibroblasts with the BH3 mimetic ABT-263 reverses established fibrosis Autor David Lagares, Alba Santos, Paula Grasberger, Fei Liu, Clemens K. Probst, Rod A. Rahimi, Norihiko Sakai, Tobias Kuehl, Jeremy Ryan, Patrick Bhola, Joan Montero, Mohit Kapoor, Murray Baron, Xaralabos Varelas, Daniel J. Tschumperlin, Anthony Letai, Andrew M. Tager

    Vydáno 2017
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  11. 11
    Blastic Plasmacytoid Dendritic Cell Neoplasm Is Dependent on BCL2 and Sensitive to Venetoclax

    Blastic Plasmacytoid Dendritic Cell Neoplasm Is Dependent on BCL2 and Sensitive to Venetoclax Autor Joan Montero, Jason Stephansky, Tianyu Cai, Gabriel K. Griffin, Lucía Cabal‐Hierro, Katsuhiro Togami, Leah J. Hogdal, Ilene Galinsky, Elizabeth A. Morgan, Jon C. Aster, Matthew S. Davids, Nicole R. LeBoeuf, Richard M. Stone, Marina Konopleva, Naveen Pemmaraju, Anthony Letai, Andrew A. Lane

    Vydáno 2016
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  12. 12
    DNA methyltransferase inhibition overcomes diphthamide pathway deficiencies underlying CD123-targeted treatment resistance

    DNA methyltransferase inhibition overcomes diphthamide pathway deficiencies underlying CD123-targeted treatment resistance Autor Katsuhiro Togami, Timothy J. Pastika, Jason Stephansky, Mahmoud Ghandi, Amanda L. Christie, Kristen L. Jones, C. Anderson Johnson, Ross Lindsay, Christopher Brooks, Anthony Letai, Jeffrey W. Craig, Olga Pozdnyakova, David M. Weinstock, Joan Montero, Jon C. Aster, Cory M. Johannessen, Andrew A. Lane

    Vydáno 2019
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  13. 13
    Fatty acid synthase (FASN) regulates the mitochondrial priming of cancer cells

    Fatty acid synthase (FASN) regulates the mitochondrial priming of cancer cells Autor Barbara Schroeder, Travis Vander Steen, Ingrid Espinoza, Chandra M. K. Venkatapoorna, Zeng Hu, Fernando Martín, Kevin M. Regan, Elisabet Cuyàs, X. Wei Meng, Sara Verdura, Aina Arbusà, Paula A. Schneider, Karen S. Flatten, George Kemble, Joan Montero, Scott H. Kaufmann, Javier A. Menéndez, Ruth Lupu

    Vydáno 2021
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  14. 14
    The 2-oxoglutarate carrier promotes liver cancer by sustaining mitochondrial GSH despite cholesterol loading

    The 2-oxoglutarate carrier promotes liver cancer by sustaining mitochondrial GSH despite cholesterol loading Autor Anna Baulies, Joan Montero, Núria Matías, Naroa Insausti-Urkia, Oihana Terrones, Gorka Basáñez, Carmen G. Vallejo, Laura Conde de la Rosa, Laura Martinez‐Gili, David Robles, Albert Morales, Joaquín Abián, Montserrat Carrascal, Keigo Machida, Dinesh Babu Uthaya Kumar, Hidekazu Tsukamoto, Neil Kaplowitz, Carmen Garcı́a-Ruiz, José C. Fernández–Checa

    Vydáno 2017
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  15. 15
    Reactivation of ERK Signaling Causes Resistance to EGFR Kinase Inhibitors

    Reactivation of ERK Signaling Causes Resistance to EGFR Kinase Inhibitors Autor Dalia Ercan, Chunxiao Xu, Masahiko Yanagita, Calixte S. Monast, Christine A. Pratilas, Joan Montero, Mohit Butaney, Takeshi Shimamura, Lynette M. Sholl, Elena Ivanova, Madhavi Tadi, Andrew M. Rogers, Claire E. Repellin, Marzia Capelletti, Ophélia Maertens, Eva M. Goetz, Anthony Letai, Levi A. Garraway, Matthew J. Lazzara, Neal Rosen, Nathanael S. Gray, Kwok‐Kin Wong, Pasi A. Jänne

    Vydáno 2012
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  16. 16
    Activity of a selective inhibitor of nuclear export, selinexor (KPT-330), against AML-initiating cells engrafted into immunosuppressed NSG mice

    Activity of a selective inhibitor of nuclear export, selinexor (KPT-330), against AML-initiating cells engrafted into immunosuppressed NSG mice Autor Julia Etchin, Joan Montero, Alla Berezovskaya, Bonnie Le, Alex Kentsis, Amanda L. Christie, Amy Saur Conway, W C Chen, Casie Reed, Marc R. Mansour, Cherry Ee Lin Ng, Sophia Adamia, Scott J. Rodig, Ilene Galinsky, Richard M. Stone, Boris Klebanov, Yosef Landesman, Michael Kauffman, Sharon Shacham, Andrew L. Kung, Jean Wang, Anthony Letai, A. Thomas Look

    Vydáno 2015
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  17. 17
    BH3 mimetics targeting BCL-XL impact the senescent compartment of pilocytic astrocytoma

    BH3 mimetics targeting BCL-XL impact the senescent compartment of pilocytic astrocytoma Autor Florian Selt, Romain Sigaud, Gintvile Valinciute, Philipp Sievers, Julia Zaman, Clara Alcon, Simone Schmid, Heike Peterziel, Jessica W. Tsai, Romain Guiho, Juan Pedro Martı́nez-Barberá, Stefan Pusch, Jing Deng, Yifan Zhai, Cornelis M. van Tilburg, Martin U Schuhman, Ahmed El Damaty, Pratiti Bandopadhayay, Christel Herold‐Mende, Andreas von Deimling, Stefan M. Pfister, Joan Montero, David Capper, Ina Oehme, Felix Sahm, David Jones, Olaf Witt, Till Milde

    Vydáno 2022
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  18. 18
    Pooled Genomic Screens Identify Anti-apoptotic Genes as Targetable Mediators of Chemotherapy Resistance in Ovarian Cancer

    Pooled Genomic Screens Identify Anti-apoptotic Genes as Targetable Mediators of Chemotherapy Resistance in Ovarian Cancer Autor Elizabeth H. Stover, Maria B. Baco, Ofir Cohen, Yvonne Y. Li, Elizabeth L. Christie, Mukta Bagul, Amy Goodale, Yenarae Lee, Sasha Pantel, Matthew G. Rees, Guo Wei, Adam G. Presser, Maya K. Gelbard, Weiqun Zhang, Ioannis K. Zervantonakis, Patrick Bhola, Jeremy Ryan, Jennifer L. Guerriero, Joan Montero, Felice J. Liang, Andrew D. Cherniack, Federica Piccioni, Ursula A. Matulonis, David D.L. Bowtell, Kristopher A. Sarosiek, Anthony Letai, Levi A. Garraway, Cory M. Johannessen, Matthew Meyerson

    Vydáno 2019
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  19. 19
    CDK4/6 inhibition reprograms the breast cancer enhancer landscape by stimulating AP-1 transcriptional activity

    CDK4/6 inhibition reprograms the breast cancer enhancer landscape by stimulating AP-1 transcriptional activity Autor April C. Watt, Paloma Cejas, Molly J. DeCristo, Otto Metzger, Enid Y.N. Lam, Xintao Qiu, Haley BrinJones, Nikolas Kesten, Rhiannon Coulson, Alba Font‐Tello, Klothilda Lim, Raga Vadhi, Veerle W. Daniëls, Joan Montero, Len Taing, Clifford A. Meyer, Omer Gilan, Charles C. Bell, Keegan Korthauer, Claudia Giambartolomei, Bogdan Paşaniuc, Ji-Heui Seo, Matthew L. Freedman, X. Cynthia, Matthew J. Ellis, Ian E. Krop, Eric P. Winer, Anthony Letai, Myles Brown, Mark A. Dawson, Henry W. Long, Jean J. Zhao, Shom Goel

    Vydáno 2020
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  20. 20
    Activity of the Type II JAK2 Inhibitor CHZ868 in B Cell Acute Lymphoblastic Leukemia

    Activity of the Type II JAK2 Inhibitor CHZ868 in B Cell Acute Lymphoblastic Leukemia Autor Shuo-Chieh Wu, Loretta S. Li, Nadja Kopp, Joan Montero, Bjoern Chapuy, Akinori Yoda, Amanda L. Christie, Huiyun Liu, Alexandra Christodoulou, Diederik van Bodegom, Jordy Van Der Zwet, Jacob V. Layer, Trevor Tivey, Andrew A. Lane, Jeremy Ryan, Samuel Y. Ng, Daniel J. DeAngelo, Richard M. Stone, David P. Steensma, Martha Wadleigh, Marian H. Harris, Emeline Mandon, Nicolas Ebel, Rita Andraos, Vincent Romanet, Arno Dölemeyer, Dario Sterker, Michael Zender, Scott J. Rodig, Masato Murakami, Francesco Hofmann, Frank C. Kuo, Michael J. Eck, Lewis B. Silverman, Stephen E. Sallan, Anthony Letai, Fabienne Baffert, Eric Vangrevelinghe, Thomas Radimerski, Christoph Gaul, David M. Weinstock

    Vydáno 2015
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