Resultats de la cerca - Jing‐Tao Wu
- Mostrar 1 - 7 resultats de 7
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Nonclinical Pharmacokinetics and Absorption, Distribution, Metabolism, and Excretion of Givosiran, the First Approved <i>N</i>-Acetylgalactosamine–Conjugated RNA Interference Thera... per Jing Li, Ju Liu, Xuemei Zhang, Valerie A. Clausen, Chris Tran, Michael Arciprete, Qianfan Wang, Carrie Rocca, Lihua Guan, Guodong Zhang, Diana Najarian, Yuanxin Xu, Pete Smith, Jing‐Tao Wu, Saeho Chong
Publicat 2021Artigo -
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Evaluating the oral delivery of GalNAc-conjugated siRNAs in rodents and non-human primates per Mikyung Yu, June Qin, Xiumin Liu, Diane Ramsden, Brian Williams, Ivan Zlatev, Dale C. Guenther, Shigeo Matsuda, Roxanne Tymon, Justin Darcy, Catrina Wong, Jamie Tsung, Peter Zawaneh, Saeho Chong, Christopher S. Theile, Nathan Taneja, Arlin B. Rogers, Ju Liu, Elena Castellanos-Rizaldos, Sarah Bond, Kawai So, Jason Denoncourt, Adam Castoreno, Muthiah Manoharan, Jing‐Tao Wu, Kevin Fitzgerald, Martin A. Maier, Vasant Jadhav, Jayaprakash K. Nair
Publicat 2024Artigo -
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Safety evaluation of 2′-deoxy-2′-fluoro nucleotides in GalNAc-siRNA conjugates per Maja M. Janas, Ivan Zlatev, Ju Liu, Yongfeng Jiang, Scott Barros, Jessica E. Sutherland, Wendell Davis, Jingxuan Liu, Christopher R. Brown, Xiumin Liu, Mark K. Schlegel, Lauren P. Blair, Xuemei Zhang, Biplab Das, Chris Tran, Krishna Aluri, Jing Li, Saket Agarwal, Ramesh Indrakanti, Klaus Charissé, Jayaprakash K. Nair, Shigeo Matsuda, Kallanthottathil G. Rajeev, Tracy Zimmermann, Laura Sepp‐Lorenzino, Yuanxin Xu, Akin Akinc, Kevin Fitzgerald, Akshay Vaishnaw, Peter F. Smith, Muthiah Manoharan, Vasant Jadhav, Jing‐Tao Wu, Martin A. Maier
Publicat 2019Artigo -
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The Nonclinical Disposition and Pharmacokinetic/Pharmacodynamic Properties of <i>N</i>-Acetylgalactosamine–Conjugated Small Interfering RNA Are Highly Predictable and Build Confide... per Robin McDougall, Diane Ramsden, Sagar Agarwal, Saket Agarwal, Krishna Aluri, Michael Arciprete, Christopher R. Brown, Elena Castellanos-Rizaldos, Klaus Charissé, Saeho Chong, Joseph A. Cichocki, Kevin Fitzgerald, Varun Goel, Yongli Gu, Dale C. Guenther, Bahru Habtemariam, Vasant Jadhav, Maja M. Janas, Muthusamy Jayaraman, Jeffrey C. Kurz, Jing Li, Ju Liu, Xiumin Liu, Steven Liou, Chris Maclauchlin, Martin A. Maier, Muthiah Manoharan, Jayaprakash K. Nair, Gabriel J. Robbie, Karyn Schmidt, Pete Smith, Christopher S. Theile, Akshay Vaishnaw, Scott Waldron, Yuanxin Xu, Xuemei Zhang, Ivan Zlatev, Jing‐Tao Wu
Publicat 2021Revisão -
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Expanding RNAi therapeutics to extrahepatic tissues with lipophilic conjugates per Kirk Brown, Jayaprakash K. Nair, Maja M. Janas, Yesseinia I. Angleró-Rodríguez, Lan Dang, Haiyan Peng, Christopher S. Theile, Elena Castellanos-Rizaldos, Christopher R. Brown, Donald J. Foster, Jeffrey C. Kurz, Jeffrey C. Allen, Rajanikanth J Maganti, Jing Li, Shigeo Matsuda, Matthew Stricos, Tyler Chickering, Michelle Jung, Kelly Wassarman, Jeff Rollins, Lauren Blair Woods, Alex Kelin, Dale C. Guenther, Melissa W. Mobley, John R. Petrulis, Robin McDougall, Timothy Racie, Jessica Bombardier, Diana Cha, Saket Agarwal, Lei Johnson, Yongfeng Jiang, Scott Lentini, Jason A. Gilbert, Tuyen Nguyen, Samantha Chigas, Sarah LeBlanc, Urjana Poreci, Anne Kasper, Arlin B. Rogers, Saeho Chong, Wendell Davis, Jessica E. Sutherland, Adam Castoreno, Stuart Milstein, Mark K. Schlegel, Ivan Zlatev, Klaus Charissé, Mark Keating, Muthiah Manoharan, Kevin Fitzgerald, Jing‐Tao Wu, Martin A. Maier, Vasant Jadhav
Publicat 2022Artigo
Eines de cerca:
Matèries relacionades
Biochemistry
Biology
Gene
Chemistry
Pharmacology
RNA
Small interfering RNA
In vitro
In vivo
Medicine
ADME
Biotechnology
Cell
Cell biology
Immunology
Oligonucleotide
Pharmacokinetics
RNA interference
Adhesion
Alternative medicine
Asialoglycoprotein receptor
Barrier function
Betaine
Bioavailability
Biodistribution
Cell adhesion
Cell adhesion molecule
Central nervous system
Claudin
Cytochrome P450