Resultats de la cerca - Jeremy R. Graff

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  1. 1
    eIF-4E expression and its role in malignancies and metastases

    eIF-4E expression and its role in malignancies and metastases per Arrigo De Benedetti, Jeremy R. Graff

    Publicat 2004
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  2. 2
    Targeting the eIF4F Translation Initiation Complex: A Critical Nexus for Cancer Development

    Targeting the eIF4F Translation Initiation Complex: A Critical Nexus for Cancer Development per Jerry Pelletier, Jeremy R. Graff, Davide Ruggero, Nahum Sonenberg

    Publicat 2015
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  3. 3
    Targeting the Eukaryotic Translation Initiation Factor 4E for Cancer Therapy

    Targeting the Eukaryotic Translation Initiation Factor 4E for Cancer Therapy per Jeremy R. Graff, Bruce W. Konicek, Julia H. Carter, Eric G. Marcusson

    Publicat 2008
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  4. 4
    Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

    Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. per James G. Herman, Jeremy R. Graff, Sanna Myöhänen, B D Nelkin, S B Baylin

    Publicat 1996
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  5. 5
    Methylation Patterns of the E-cadherin 5′ CpG Island Are Unstable and Reflect the Dynamic, Heterogeneous Loss of E-cadherin Expression during Metastatic Progression

    Methylation Patterns of the E-cadherin 5′ CpG Island Are Unstable and Reflect the Dynamic, Heterogeneous Loss of E-cadherin Expression during Metastatic Progression per Jeremy R. Graff, Edward Gabrielson, Hiraoki Fujii, Stephen B. Baylin, James G. Herman

    Publicat 2000
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  6. 6
    Hypomethylation of pericentromeric DNA in breast adenocarcinomas

    Hypomethylation of pericentromeric DNA in breast adenocarcinomas per Ajita Narayan, Weizhen Ji, Xian-Yang Zhang, Aizen J. Marrogi, Jeremy R. Graff, Stephen B. Baylin, Melanie Ehrlich

    Publicat 1998
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  7. 7
    Cotargeting MNK and MEK kinases induces the regression of NF1-mutant cancers

    Cotargeting MNK and MEK kinases induces the regression of NF1-mutant cancers per Rebecca Lock, Rachel Ingraham, Ophélia Maertens, Abigail L. Miller, Nelly Weledji, Eric Legius, Bruce M. Konicek, S. Betty Yan, Jeremy R. Graff, Karen Cichowski

    Publicat 2016
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  8. 8
    Inhibition of Mnk kinase activity by cercosporamide and suppressive effects on acute myeloid leukemia precursors

    Inhibition of Mnk kinase activity by cercosporamide and suppressive effects on acute myeloid leukemia precursors per Jessica K. Altman, Amy Szilard, Bruce W. Konicek, Philip W. Iversen, Barbara Kroczyńska, Heather Glaser, Antonella Sassano, Eliza Vakana, Jeremy R. Graff, Leonidas C. Platanias

    Publicat 2013
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  9. 9
    Expression of Group IIA Secretory Phospholipase A2 Is Elevated in Prostatic Intraepithelial Neoplasia and Adenocarcinoma

    Expression of Group IIA Secretory Phospholipase A2 Is Elevated in Prostatic Intraepithelial Neoplasia and Adenocarcinoma per Jiazhong Jiang, Blake Lee Neubauer, Jeremy R. Graff, Márcio F. Chedid, James E. Thomas, Neal W. Roehm, Shaobo Zhang, George J. Eckert, Michael O. Koch, John N. Eble, Liang Cheng

    Publicat 2002
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  10. 10
    Roles of trk family neurotrophin receptors in medullary thyroid carcinoma development and progression

    Roles of trk family neurotrophin receptors in medullary thyroid carcinoma development and progression per Lisa M. McGregor, Bryan K. McCune, Jeremy R. Graff, Philip R. McDowell, Katherine E. Romans, George D. Yancopoulos, Douglas W. Ball, Stephen B. Baylin, Barry D. Nelkin

    Publicat 1999
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  11. 11
    Phosphorylation of eIF4E serine 209 is associated with tumour progression and reduced survival in malignant melanoma

    Phosphorylation of eIF4E serine 209 is associated with tumour progression and reduced survival in malignant melanoma per Julia H. Carter, James A. Deddens, Nelson Reed Spaulding, Denise Lucas, Bruce M. Colligan, Thomas G. Lewis, Elyse Hawkins, Jordan Jones, Jackson O. Pemberton, Larry E. Douglass, Jeremy R. Graff

    Publicat 2016
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  12. 12
    Increased AKT Activity Contributes to Prostate Cancer Progression by Dramatically Accelerating Prostate Tumor Growth and Diminishing p27Kip1 Expression

    Increased AKT Activity Contributes to Prostate Cancer Progression by Dramatically Accelerating Prostate Tumor Growth and Diminishing p27Kip1 Expression per Jeremy R. Graff, Bruce W. Konicek, Ann M. McNulty, Zejing Wang, Keith A. Houck, Sheryl Allen, Jonathan Paul, Ahed Hbaiu, Robin G. Goode, George E. Sandusky, Robert L. Vessella, Blake Lee Neubauer

    Publicat 2000
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  13. 13
    Pharmacogenetic Inhibition of eIF4E-Dependent Mmp9 mRNA Translation Reverses Fragile X Syndrome-like Phenotypes

    Pharmacogenetic Inhibition of eIF4E-Dependent Mmp9 mRNA Translation Reverses Fragile X Syndrome-like Phenotypes per Christos G. Gkogkas, Arkady Khoutorsky, Ruifeng Cao, Seyed Mehdi Jafarnejad, Masha Prager‐Khoutorsky, N. Giannakas, Archontia Kaminari, Apostolia Fragkouli, Karim Nader, Theodore J. Price, Bruce W. Konicek, Jeremy R. Graff, Athina Tzinia, Jean‐Claude Lacaille, Nahum Sonenberg

    Publicat 2014
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  14. 14
    Imprime PGG-Mediated Anti-Cancer Immune Activation Requires Immune Complex Formation

    Imprime PGG-Mediated Anti-Cancer Immune Activation Requires Immune Complex Formation per Anissa Chan, Adria Bykowski Jonas, Xiaohong Qiu, Nadine Ottoson, Richard M. Walsh, Keith Gorden, Ben Harrison, Peter Maimonis, Steven Leonardo, Kathleen Ertelt, Michael E. Danielson, Kyle S. Michel, Mariana I. Nelson, Jeremy R. Graff, Myra L. Patchen, Nandita Bose

    Publicat 2016
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  15. 15
    Incidence and functional consequences of <i>hMLH1</i> promoter hypermethylation in colorectal carcinoma

    Incidence and functional consequences of <i>hMLH1</i> promoter hypermethylation in colorectal carcinoma per James G. Herman, Asad Umar, Kornélia Polyák, Jeremy R. Graff, Nita Ahuja, Jean–Pierre J. Issa, Sanford D. Markowitz, James K. V. Willson, Stanley R. Hamilton, Kenneth W. Kinzler, Michael Kane, Richard D. Kolodner, Bert Vogelstein, Thomas A. Kunkel, Stephen B. Baylin

    Publicat 1998
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  16. 16
    Therapeutic Inhibition of MAP Kinase Interacting Kinase Blocks Eukaryotic Initiation Factor 4E Phosphorylation and Suppresses Outgrowth of Experimental Lung Metastases

    Therapeutic Inhibition of MAP Kinase Interacting Kinase Blocks Eukaryotic Initiation Factor 4E Phosphorylation and Suppresses Outgrowth of Experimental Lung Metastases per Bruce W. Konicek, Jennifer R. Stephens, Ann M. McNulty, Nathaniel Robichaud, Robert B. Peery, Chad A. Dumstorf, Michele Dowless, Philip W. Iversen, Stephen H. Parsons, Karen E. Ellis, Denis McCann, Jerry Pelletier, Luc Furic, Jonathan M. Yingling, Louis F. Stancato, Nahum Sonenberg, Jeremy R. Graff

    Publicat 2011
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  17. 17
    eIF4E Activation Is Commonly Elevated in Advanced Human Prostate Cancers and Significantly Related to Reduced Patient Survival

    eIF4E Activation Is Commonly Elevated in Advanced Human Prostate Cancers and Significantly Related to Reduced Patient Survival per Jeremy R. Graff, Bruce W. Konicek, Rebecca L. Lynch, Chad A. Dumstorf, Michele Dowless, Ann M. McNulty, Stephen H. Parsons, Leslie H. Brail, Bruce M. Colligan, Jonathan W. Koop, Bernadette M. Hurst, James A. Deddens, Blake Lee Neubauer, Louis F. Stancato, Harry W. Carter, Larry E. Douglass, Julia H. Carter

    Publicat 2009
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  18. 18
    The Protein Kinase Cβ–Selective Inhibitor, Enzastaurin (LY317615.HCl), Suppresses Signaling through the AKT Pathway, Induces Apoptosis, and Suppresses Growth of Human Colon Cancer and Glioblastoma Xenografts

    The Protein Kinase Cβ–Selective Inhibitor, Enzastaurin (LY317615.HCl), Suppresses Signaling through the AKT Pathway, Induces Apoptosis, and Suppresses Growth of Human Colon Cancer... per Jeremy R. Graff, Ann M. McNulty, Kimberly R. Hanna, Bruce W. Konicek, Rebecca L. Lynch, Spring N. Bailey, Crystal Banks, Andrew Capen, Robin L. Goode, Jason E. Lewis, Lillian Sams, Karen Huss, Robert M. Campbell, Philip W. Iversen, Blake Lee Neubauer, Thomas J. Brown, Luna Musib, Sandaruwan Geeganage, Donald Thornton

    Publicat 2005
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  19. 19
    LY2801653 is an orally bioavailable multi-kinase inhibitor with potent activity against MET, MST1R, and other oncoproteins, and displays anti-tumor activities in mouse xenograft models

    LY2801653 is an orally bioavailable multi-kinase inhibitor with potent activity against MET, MST1R, and other oncoproteins, and displays anti-tumor activities in mouse xenograft mo... per S. Betty Yan, Victoria L. Peek, Rose T. Ajamie, Sean G. Buchanan, Jeremy R. Graff, Steven A. Heidler, Yu‐Hua Hui, Karen Huss, Bruce W. Konicek, Jason R. Manro, Chuan Shih, Julie Stewart, Trent R. Stewart, Stephanie L. Stout, Mark Uhlik, Suzane L. Um, Yong Wang, Wenjuan Wu, Lei Yan, Wei Yang, Boyu Zhong, Richard A. Walgren

    Publicat 2012
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  20. 20
    Characterization of LY2228820 Dimesylate, a Potent and Selective Inhibitor of p38 MAPK with Antitumor Activity

    Characterization of LY2228820 Dimesylate, a Potent and Selective Inhibitor of p38 MAPK with Antitumor Activity per Robert M. Campbell, Bryan D. Anderson, Nathan A. Brooks, Harold B. Brooks, Edward M. Chan, Alfonso de Dios, Raymond Gilmour, Jeremy R. Graff, Enrique Jambrina, Mary M. Mader, Denis McCann, Songqing Na, Stephen H. Parsons, Susan E. Pratt, Chuan Shih, Louis F. Stancato, James J. Starling, Courtney M. Tate, Juan A. Velasco, Yong Wang, Xiang S. Ye

    Publicat 2013
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