检索结果 - Jennifer A. Roth

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  1. 1
    Methionine synthase is essential for cancer cell proliferation in physiological folate environments

    Methionine synthase is essential for cancer cell proliferation in physiological folate environments 由 Mark R. Sullivan, Alicia M. Darnell, Montana F. Reilly, Tenzin Kunchok, Lena Joesch-Cohen, Daniel W. Rosenberg, Ahmed Ali, Matthew G. Rees, Jennifer A. Roth, Caroline A. Lewis, Matthew G. Vander Heiden

    出版 2021
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  2. 2
    Salvage of ribose from uridine or RNA supports glycolysis in nutrient-limited conditions

    Salvage of ribose from uridine or RNA supports glycolysis in nutrient-limited conditions 由 Owen S. Skinner, Joan Blanco-Fernández, Russell P. Goodman, Akinori Kawakami, Hongying Shen, Lajos V. Kemény, Lena Joesch-Cohen, Matthew G. Rees, Jennifer A. Roth, David E. Fisher, Vamsi K. Mootha, Alexis A. Jourdain

    出版 2023
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  3. 3
    Constitutive Activation of Signal Transducers and Activators of Transcription Predicts Vorinostat Resistance in Cutaneous T-Cell Lymphoma

    Constitutive Activation of Signal Transducers and Activators of Transcription Predicts Vorinostat Resistance in Cutaneous T-Cell Lymphoma 由 Valeria R. Fantin, Andrey Loboda, Cloud P. Paweletz, Ronald C. Hendrickson, Jacqueline W. Pierce, Jennifer A. Roth, Lixia Li, Frank Gooden, Susan Korenchuk, Xiaoli Hou, Elizabeth A. Harrington, Sophia Randolph, John F. Reilly, Christopher Ware, Marshall E. Kadin, Stanley R. Frankel, Victoria M. Richon

    出版 2008
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  4. 4
    A metastasis map of human cancer cell lines

    A metastasis map of human cancer cell lines 由 Xin Jin, Zelalem Demere, Karthik Nair, Ahmed Ali, Gino B. Ferraro, Ted Natoli, Amy Deik, L Petronio, Andrew Tang, Cong Zhu, Li Wang, Danny Rosenberg, Vamsi Mangena, Jennifer A. Roth, Kwanghun Chung, Rakesh K. Jain, Clary B. Clish, Matthew G. Vander Heiden, Todd R. Golub

    出版 2020
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  5. 5
    Massively parallel pooled screening reveals genomic determinants of nanoparticle delivery

    Massively parallel pooled screening reveals genomic determinants of nanoparticle delivery 由 Natalie Boehnke, Joelle P. Straehla, Hannah C. Safford, Mustafa Kocak, Matthew G. Rees, Melissa M. Ronan, Danny Rosenberg, Charles H. Adelmann, Raghu R. Chivukula, Namita Nabar, Adam G. Berger, Nicholas G. Lamson, Jaime H. Cheah, Hojun Li, Jennifer A. Roth, Angela N. Koehler, Paula T. Hammond

    出版 2022
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  6. 6
    Structure-Based Design of Y-Shaped Covalent TEAD Inhibitors

    Structure-Based Design of Y-Shaped Covalent TEAD Inhibitors 由 Wenchao Lu, Mengyang Fan, Wenzhi Ji, Jason Tse, Inchul You, Scott B. Ficarro, Isidoro Tavares, Jianwei Che, Audrey Y. Kim, Xijun Zhu, Andrew S. Boghossian, Matthew G. Rees, Melissa M. Ronan, Jennifer A. Roth, Stephen M. Hinshaw, Behnam Nabet, Steven M. Corsello, Nicholas Kwiatkowski, Jarrod A. Marto, Tinghu Zhang, Nathanael S. Gray

    出版 2023
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  7. 7
    Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action

    Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action 由 James M. McFarland, Brenton R. Paolella, Allison Warren, Kathryn Geiger‐Schuller, Tsukasa Shibue, Michael Rothberg, Olena Kuksenko, William Colgan, Andrew Jones, Emily S. Chambers, Danielle Dionne, Samantha Bender, Brian M. Wolpin, Mahmoud Ghandi, Itay Tirosh, Orit Rozenblatt–Rosen, Jennifer A. Roth, Todd R. Golub, Aviv Regev, Andrew J. Aguirre, Francisca Vázquez, Aviad Tsherniak

    出版 2020
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  8. 8
    Targeted degradation of CDK9 potently disrupts the MYC-regulated network

    Targeted degradation of CDK9 potently disrupts the MYC-regulated network 由 Mohammed A. Toure, Keisuke Motoyama, Yichen Xiang, Julie Urgiles, Florian Kabinger, Ann-Sophie Koglin, Ramya S. Iyer, Kaitlyn Gagnon, Amruth Kumar, Samuel Ojeda, Drew A. Harrison, Matthew G. Rees, Jennifer A. Roth, Christopher J. Ott, Richard P. Schiavoni, Charles A. Whittaker, Stuart S. Levine, Forest M. White, Eliezer Calo, André Richters, Angela N. Koehler

    出版 2025
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  9. 9
    Pan-cancer single cell RNA-seq uncovers recurring programs of cellular heterogeneity

    Pan-cancer single cell RNA-seq uncovers recurring programs of cellular heterogeneity 由 Gabriela Sarti Kinker, Alissa C. Greenwald, Rotem Tal, Zhanna Orlova, Michael S. Cuoco, James M. McFarland, Allison Warren, Christopher Rodman, Jennifer A. Roth, Samantha Bender, Bhavna Kumar, James W. Rocco, Pedro ACM Fernandes, Christopher C. Mader, Hadas Keren‐Shaul, A.N. Plotnikov, Haim Barr, Aviad Tsherniak, Orit Rozenblatt–Rosen, Valery Krizhanovsky, Sidharth V. Puram, Aviv Regev, Itay Tirosh

    出版 2019
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  10. 10
    INK4 Tumor Suppressor Proteins Mediate Resistance to CDK4/6 Kinase Inhibitors

    INK4 Tumor Suppressor Proteins Mediate Resistance to CDK4/6 Kinase Inhibitors 由 Qing Li, Baishan Jiang, Jiaye Guo, Hong Shao, Isabella Del Priore, Qing Chang, Rei Kudo, Zhiqiang Li, Pedram Razavi, Bo Liu, Andrew S. Boghossian, Matthew G. Rees, Melissa M. Ronan, Jennifer A. Roth, Katherine A. Donovan, Marta Palafox, Jorge S. Reis‐Filho, Elisa de Stanchina, Eric S. Fischer, Neal Rosen, Violeta Serra, Andrew Koff, John D. Chodera, Nathanael S. Gray, Sarat Chandarlapaty

    出版 2021
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  11. 11
    BRD-810 is a highly selective MCL1 inhibitor with optimized in vivo clearance and robust efficacy in solid and hematological tumor models

    BRD-810 is a highly selective MCL1 inhibitor with optimized in vivo clearance and robust efficacy in solid and hematological tumor models 由 Ulrike Rauh, Wei Guo, Michael H. Serrano‐Wu, Georgios Kosmidis, Stefan Kaulfuß, Franziska Siegel, Kai Thede, James M. McFarland, Christopher T. Lemke, Nicolas D. Werbeck, Katrin Nowak‐Reppel, Sabine Pilari, Stephan Menz, Matthias Ocker, Weiqun Zhang, Kyle Frankel Davis, G. Poncet-Montange, Jennifer A. Roth, Douglas S. Daniels, Virendar K. Kaushik, Brian K. Hubbard, Karl Ziegelbauer, Todd R. Golub

    出版 2024
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  12. 12
    Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity

    Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity 由 Gabriela Sarti Kinker, Alissa C. Greenwald, Rotem Tal, Zhanna Orlova, Michael S. Cuoco, James M. McFarland, Allison Warren, Christopher Rodman, Jennifer A. Roth, Samantha Bender, Bhavna Kumar, James W. Rocco, Pedro Augusto Carlos Magno Fernandes, Christopher C. Mader, Hadas Keren‐Shaul, A.N. Plotnikov, Haim Barr, Aviad Tsherniak, Orit Rozenblatt–Rosen, Valery Krizhanovsky, Sidharth V. Puram, Aviv Regev, Itay Tirosh

    出版 2020
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  13. 13
    Noncanonical open reading frames encode functional proteins essential for cancer cell survival

    Noncanonical open reading frames encode functional proteins essential for cancer cell survival 由 John R. Prensner, Oana M. Enache, Victor Luria, Karsten Krug, Karl R. Clauser, Joshua M. Dempster, Amir Karger, Li Wang, Karolina Stumbraite, Vickie M. Wang, Ginevra Botta, Nicholas Lyons, Amy Goodale, Zohra Kalani, Briana Fritchman, Adam Brown, Douglas Alan, Thomas Green, Xiaoping Yang, Jacob D. Jaffe, Jennifer A. Roth, Federica Piccioni, Marc W. Kirschner, Zhe Ji, David E. Root, Todd R. Golub

    出版 2021
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  14. 14
    Covalent disruptor of YAP-TEAD association suppresses defective Hippo signaling

    Covalent disruptor of YAP-TEAD association suppresses defective Hippo signaling 由 Mengyang Fan, Wenchao Lu, Jianwei Che, Nicholas Kwiatkowski, Yang Gao, Hyuk‐Soo Seo, Scott B. Ficarro, Prafulla C. Gokhale, Yao Liu, Ezekiel A. Geffken, Jimit Lakhani, Kijun Song, Miljan Kuljanin, Wenzhi Ji, Jie Jiang, Zhixiang He, Jason Tse, Andrew S. Boghossian, Matthew G. Rees, Melissa M. Ronan, Jennifer A. Roth, Joseph D. Mancias, Jarrod A. Marto, Sirano Dhe‐Paganon, Tinghu Zhang, Nathanael S. Gray

    出版 2022
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  15. 15
    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma

    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma 由 Damon A. Hofman, Jorge Ruiz‐Orera, Ian Yannuzzi, Rakesh Murugesan, Adam Brown, Karl R. Clauser, Alexandra L. Condurat, Jip T. van Dinter, Sem A.G. Engels, Amy Goodale, Jasper van der Lugt, Tanaz Abid, Li Wang, Kevin N. Zhou, Jayne Vogelzang, Keith L. Ligon, Timothy N. Phoenix, Jennifer A. Roth, David E. Root, Norbert Hübner, Todd R. Golub, Pratiti Bandopadhayay, Sebastiaan van Heesch, John R. Prensner

    出版 2024
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  16. 16
    An Embryonic Diapause-like Adaptation with Suppressed Myc Activity Enables Tumor Treatment Persistence

    An Embryonic Diapause-like Adaptation with Suppressed Myc Activity Enables Tumor Treatment Persistence 由 Eugen Dhimolea, Ricardo De Matos Simoes, Dhvanir Kansara, Aziz Al’Khafaji, Juliette Bouyssou, Xiang Weng, Shruti Sharma, Joseline Raja, Pallavi Awate, Ryosuke Shirasaki, Huihui Tang, Brian Glassner, Zhiyi Liu, Dong Gao, Jordan Bryan, Samantha Bender, Jennifer A. Roth, Michal Scheffer, Rinath Jeselsohn, Nathanael S. Gray, Irene Georgakoudi, Francisca Vázquez, Aviad Tsherniak, Yu Chen, Alana L. Welm, Cihangir Duy, Ari Melnick, Boris Bartholdy, Myles Brown, Aedín C. Culhane, Constantine S. Mitsiades

    出版 2021
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  17. 17
    Single-cell functional genomics reveals determinants of sensitivity and resistance to natural killer cells in blood cancers

    Single-cell functional genomics reveals determinants of sensitivity and resistance to natural killer cells in blood cancers 由 Olli Dufva, Sara Gandolfi, Jani Huuhtanen, Olga Dashevsky, Hanna Duàn, Khalid Saeed, Jay Klievink, Petra Nygren, Jonas Bouhlal, Jenni Lahtela, Anna Näätänen, Bishwa Ghimire, Tiina Hannunen, Pekka Ellonen, Hanna Lähteenmäki, Pauliina Rumm, Jason Theodoropoulos, Essi Laajala, Jouni Härkönen, Petri Pölönen, Merja Heinäniemi, Maija Hollmén, Shizuka Yamano, Ryosuke Shirasaki, David A. Barbie, Jennifer A. Roth, Rizwan Romee, Michal Sheffer, Harri Lähdesmäki, Dean A. Lee, Ricardo De Matos Simoes, Matti Kankainen, Constantine S. Mitsiades, Satu Mustjoki

    出版 2023
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  18. 18
    Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancers

    Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancers 由 Marc Payton, Brian Belmontes, Kelly Hanestad, Jodi Moriguchi, Kui Chen, John D. McCarter, Grace Chung, Maria Stefania S. Ninniri, Jan Sun, Raffi Manoukian, Stuart Chambers, Seok‐Man Ho, Robert J. Kurzeja, Katheryne Z. Edson, Upendra P. Dahal, Tian Wu, Sharon Wannberg, Pedro J. Beltran, Jude Canon, Andrew S. Boghossian, Matthew G. Rees, Melissa M. Ronan, Jennifer A. Roth, Sheroy Minocherhomji, Matthew P. Bourbeau, Jennifer R. Allen, Angela Coxon, Nuria Tamayo, Paul E. Hughes

    出版 2023
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  19. 19
    Discovering the anticancer potential of non-oncology drugs by systematic viability profiling

    Discovering the anticancer potential of non-oncology drugs by systematic viability profiling 由 Steven M. Corsello, Rohith T. Nagari, Ryan D. Spangler, Jordan Rossen, Mustafa Kocak, Jordan Bryan, Ranad Humeidi, D. D. Peck, Xiaoyun Wu, Andrew Tang, Vickie M. Wang, Samantha Bender, Evan Lemire, Rajiv Narayan, Philip Montgomery, Uri Ben‐David, Colin W. Garvie, Yejia Chen, Matthew G. Rees, Nicholas Lyons, James M. McFarland, Bang Wong, Li Wang, Nancy Dumont, Patrick J. O’Hearn, Eric Stefan, John G. Doench, Caitlin Harrington, Heidi Greulich, Matthew Meyerson, Francisca Vázquez, Aravind Subramanian, Jennifer A. Roth, Joshua A. Bittker, Jesse S. Boehm, Christopher C. Mader, Aviad Tsherniak, Todd R. Golub

    出版 2020
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  20. 20
    Screening in serum-derived medium reveals differential response to compounds targeting metabolism

    Screening in serum-derived medium reveals differential response to compounds targeting metabolism 由 Keene L. Abbott, Ahmed Ali, Dominick Casalena, T. Brian, Raphaël Ferreira, Jaime H. Cheah, Christian K. Soule, Amy Deik, Tenzin Kunchok, Daniel R. Schmidt, Steffen Renner, Sophie Honeder, Michelle Xiao Wu, Sze Ham Chan, Tenzin Tseyang, Andrew T. Stoltzfus, Sarah L. J. Michel, Daniel Greaves, Peggy P. Hsu, Christopher Ng, Chelsea J. Zhang, Ali Farsidjani, Johnathan R. Kent, Maria Lucia L. Madariaga, Iva Monique T. Gramatikov, Nicholas J. Matheson, Caroline A. Lewis, Clary B. Clish, Matthew G. Rees, Jennifer A. Roth, Lesley A. Mathews Griner, Alexander Muir, Douglas S. Auld, Matthew G. Vander Heiden

    出版 2023
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