Resultados de procura - Jeffrey M. Granja

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  1. 1
    High-throughput single-cell chromatin accessibility CRISPR screens enable unbiased identification of regulatory networks in cancer

    High-throughput single-cell chromatin accessibility CRISPR screens enable unbiased identification of regulatory networks in cancer por Sarah E. Pierce, Jeffrey M. Granja, William J. Greenleaf

    Publicado 2021
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  2. 2
    ArchR: An integrative and scalable software package for single-cell chromatin accessibility analysis

    ArchR: An integrative and scalable software package for single-cell chromatin accessibility analysis por Jeffrey M. Granja, M. Ryan Corces, Sarah E. Pierce, S. Tansu Bagdatli, Hani Choudhry, Howard Y. Chang, William J. Greenleaf

    Publicado 2020
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  3. 3
    ArchR is a scalable software package for integrative single-cell chromatin accessibility analysis

    ArchR is a scalable software package for integrative single-cell chromatin accessibility analysis por Jeffrey M. Granja, M. Ryan Corces, Sarah E. Pierce, S. Tansu Bagdatli, Hani Choudhry, Howard Y. Chang, William J. Greenleaf

    Publicado 2021
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  4. 4
    Entropy in molecular recognition by proteins

    Entropy in molecular recognition by proteins por A. José, Kyle W. Harpole, Vignesh Kasinath, Jackwee Lim, Jeffrey M. Granja, Kathleen G. Valentine, Kim A. Sharp, A. Joshua Wand

    Publicado 2017
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  5. 5
    Polycomb-mediated genome architecture enables long-range spreading of H3K27 methylation

    Polycomb-mediated genome architecture enables long-range spreading of H3K27 methylation por Katerina Kraft, Kathryn E. Yost, Sedona E. Murphy, Andreas Magg, Yicheng Long, M. Ryan Corces, Jeffrey M. Granja, Lars Wittler, Stefan Mundlos, Thomas R. Cech, Alistair N. Boettiger, Howard Y. Chang

    Publicado 2022
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  6. 6
    Single-cell multiomic analysis identifies regulatory programs in mixed-phenotype acute leukemia

    Single-cell multiomic analysis identifies regulatory programs in mixed-phenotype acute leukemia por Jeffrey M. Granja, Sandy Klemm, Lisa McGinnis, Arwa S. Kathiria, Anja Mezger, M. Ryan Corces, Benjamin Parks, Eric J. Gars, Michaela Liedtke, Grace Zheng, Howard Y. Chang, Ravindra Majeti, William J. Greenleaf

    Publicado 2019
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  7. 7
    LKB1 inactivation modulates chromatin accessibility to drive metastatic progression

    LKB1 inactivation modulates chromatin accessibility to drive metastatic progression por Sarah E. Pierce, Jeffrey M. Granja, M. Ryan Corces, Jennifer J. Brady, Min K. Tsai, Aubrey B. Pierce, Rui Tang, Pauline Chu, David M. Feldser, Howard Y. Chang, Michael C. Bassik, William J. Greenleaf, Monte M. Winslow

    Publicado 2021
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  8. 8
    Chromatin accessibility landscapes of skin cells in systemic sclerosis nominate dendritic cells in disease pathogenesis

    Chromatin accessibility landscapes of skin cells in systemic sclerosis nominate dendritic cells in disease pathogenesis por Qian Liu, Lisa C. Zaba, Ansuman T. Satpathy, Michelle Longmire, Wen Zhang, Kun Li, Jeffrey M. Granja, Chuang Guo, Jun Lin, Rui Li, Karen Tolentino, Gabriela Kania, Oliver Distler, David Fiorentino, Leland W.K. Chung, Kun Qu, Howard Y. Chang

    Publicado 2020
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  9. 9
    Clonal replacement of tumor-specific T cells following PD-1 blockade

    Clonal replacement of tumor-specific T cells following PD-1 blockade por Kathryn E. Yost, Ansuman T. Satpathy, Daniel K. Wells, Yanyan Qi, Chunlin Wang, Robin Kageyama, Katherine McNamara, Jeffrey M. Granja, Kavita Y. Sarin, Ryanne A. Brown, Rohit Gupta, Christina Curtis, Samantha Bucktrout, Mark M. Davis, Anne Lynn S. Chang, Howard Y. Chang

    Publicado 2019
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  10. 10
    An Nfil3–Zeb2–Id2 pathway imposes Irf8 enhancer switching during cDC1 development

    An Nfil3–Zeb2–Id2 pathway imposes Irf8 enhancer switching during cDC1 development por Prachi Bagadia, Xiao Huang, Tiantian Liu, Vivek Durai, Gary E. Grajales‐Reyes, Maximilian Nitschké, Zora Modrušan, Jeffrey M. Granja, Ansuman T. Satpathy, Carlos G. Briseño, Marco Gargaro, Arifumi Iwata, Sun Kyung Kim, Howard Y. Chang, Andréy S. Shaw, Theresa L. Murphy, Kenneth M. Murphy

    Publicado 2019
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  11. 11
    Single-cell epigenomic analyses implicate candidate causal variants at inherited risk loci for Alzheimer’s and Parkinson’s diseases

    Single-cell epigenomic analyses implicate candidate causal variants at inherited risk loci for Alzheimer’s and Parkinson’s diseases por M. Ryan Corces, Anna Shcherbina, Soumya Kundu, Michael J. Gloudemans, Laure Frésard, Jeffrey M. Granja, Bryan H. Louie, Tiffany Eulalio, Shadi Shams, S. Tansu Bagdatli, Maxwell R. Mumbach, Boxiang Liu, Kathleen S. Montine, William J. Greenleaf, Anshul Kundaje, Stephen B. Montgomery, Howard Y. Chang, Thomas J. Montine

    Publicado 2020
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  12. 12
    Intertumoral Heterogeneity in SCLC Is Influenced by the Cell Type of Origin

    Intertumoral Heterogeneity in SCLC Is Influenced by the Cell Type of Origin por Dian Yang, Sarah K. Denny, Peyton Greenside, Andrea C. Chaikovsky, Jennifer J. Brady, Youcef Ouadah, Jeffrey M. Granja, Nadine S. Jahchan, Jing Lim, Shirley Kwok, Christina S. Kong, Anna S. Berghoff, Anna Schmitt, Hans Christian Reinhardt, Kwon-Sik Park, Matthias Preusser, Anshul Kundaje, William J. Greenleaf, Julien Sage, Monte M. Winslow

    Publicado 2018
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  13. 13
    c-Jun overexpression in CAR T cells induces exhaustion resistance

    c-Jun overexpression in CAR T cells induces exhaustion resistance por Rachel C. Lynn, Evan W. Weber, Elena Sotillo, David Gennert, Peng Xu, Zinaida Good, Hima Anbunathan, John Lattin, Robert C. Jones, Victor Tieu, Surya Nagaraja, Jeffrey M. Granja, Charles F. A. de Bourcy, Robbie G. Majzner, Ansuman T. Satpathy, Stephen R. Quake, Michelle Monje, Howard Y. Chang, Crystal L. Mackall

    Publicado 2019
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  14. 14
    HiChIRP reveals RNA-associated chromosome conformation

    HiChIRP reveals RNA-associated chromosome conformation por Maxwell R. Mumbach, Jeffrey M. Granja, Ryan A. Flynn, Caitlin M. Roake, Ansuman T. Satpathy, Adam J. Rubin, Yanyan Qi, Zhaozhao Jiang, Shadi Shams, Bryan H. Louie, Jimmy K. Guo, David Gennert, M. Ryan Corces, Paul A. Khavari, Maninjay Atianand, Steven E. Artandi, Katherine A. Fitzgerald, William J. Greenleaf, Howard Y. Chang

    Publicado 2019
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  15. 15
    Cryptic activation of an Irf8 enhancer governs cDC1 fate specification

    Cryptic activation of an Irf8 enhancer governs cDC1 fate specification por Vivek Durai, Prachi Bagadia, Jeffrey M. Granja, Ansuman T. Satpathy, Devesha H. Kulkarni, Jesse T. Davidson, Renee Wu, Swapneel J. Patel, Arifumi Iwata, Tiantian Liu, Xiao Huang, Carlos G. Briseño, Gary E. Grajales‐Reyes, Miriam Wöhner, Hiromi Tagoh, Barbara L. Kee, Rodney D. Newberry, Meinrad Busslinger, Howard Y. Chang, Theresa L. Murphy, Kenneth M. Murphy

    Publicado 2019
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  16. 16
    Transcript-indexed ATAC-seq for precision immune profiling

    Transcript-indexed ATAC-seq for precision immune profiling por Ansuman T. Satpathy, Naresha Saligrama, Jason D. Buenrostro, Yuning Wei, Beijing Wu, Adam J. Rubin, Jeffrey M. Granja, Caleb A. Lareau, Rui Li, Yanyan Qi, Kevin R. Parker, Maxwell R. Mumbach, William S. Serratelli, David Gennert, Alicia N. Schep, M. Ryan Corces, Michael S. Khodadoust, Youn H. Kim, Paul A. Khavari, William J. Greenleaf, Mark M. Davis, Howard Y. Chang

    Publicado 2018
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  17. 17
    Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion

    Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion por Ansuman T. Satpathy, Jeffrey M. Granja, Kathryn E. Yost, Yanyan Qi, Francesca Meschi, Geoffrey P. McDermott, Brett N. Olsen, Maxwell R. Mumbach, Sarah E. Pierce, M. Ryan Corces, Preyas Shah, Jason C. Bell, Darisha Jhutty, Corey M. Nemec, Jean Wang, Li Wang, Yifeng Yin, Paul G. Giresi, Anne Lynn S. Chang, Grace Zheng, William J. Greenleaf, Howard Y. Chang

    Publicado 2019
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  18. 18
    Three-dimensional genome landscape of primary human cancers

    Three-dimensional genome landscape of primary human cancers por Kathryn E. Yost, Yanding Zhao, King L. Hung, Kaiyuan Zhu, Duo Xu, M. Ryan Corces, Shadi Shams, Bryan H. Louie, Shahab Sarmashghi, Laksshman Sundaram, Jens Luebeck, Stephen L. Clarke, Ashley S. Doane, Jeffrey M. Granja, Hani Choudhry, Marcin Imieliński, Andrew D. Cherniack, Ekta Khurana, Vineet Bafna, Ina Felau, Jean C. Zenklusen, Peter W. Laird, Christina Curtis, William J. Greenleaf, Howard Y. Chang

    Publicado 2025
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  19. 19
    Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements

    Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements por Maxwell R. Mumbach, Ansuman T. Satpathy, Evan A. Boyle, Chao Dai, Benjamin G. Gowen, Seung Woo Cho, Michelle Nguyen, Adam J. Rubin, Jeffrey M. Granja, Katelynn R. Kazane, Yuning Wei, Trieu Nguyen, Peyton Greenside, M. Ryan Corces, Josh Tycko, Dimitre R. Simeonov, Nabeela Suliman, Rui Li, Jin Xu, Ryan A. Flynn, Anshul Kundaje, Paul A. Khavari, Alexander Marson, Jacob E. Corn, Thomas Quertermous, William J. Greenleaf, Howard Y. Chang

    Publicado 2017
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  20. 20
    Circular ecDNA promotes accessible chromatin and high oncogene expression

    Circular ecDNA promotes accessible chromatin and high oncogene expression por Sihan Wu, Kristen M. Turner, Nam Nguyen, Ramya Raviram, Marcella L. Erb, Jennifer Santini, Jens Luebeck, Utkrisht Rajkumar, Yarui Diao, Bin Li, Wenjing Zhang, Nathan M. Jameson, M. Ryan Corces, Jeffrey M. Granja, Xingqi Chen, Ceyda Çoruh, Armen Abnousi, Jack Houston, Zhen Ye, Rong Hu, Miao Yu, Hoon Kim, Julie A. Law, Roel G.W. Verhaak, Ming Hu, Frank B. Furnari, Howard Y. Chang, Bing Ren, Vineet Bafna, Paul S. Mischel

    Publicado 2019
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