Resultados de búsqueda - Jeffrey M. Besterman

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  1. 1
    Phorbol esters rapidly stimulate amiloride-sensitive Na+/H+ exchange in a human leukemic cell line.

    Phorbol esters rapidly stimulate amiloride-sensitive Na+/H+ exchange in a human leukemic cell line. por Jeffrey M. Besterman, Pedro Cuatrecasas

    Publicado 1984
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  2. 2
    Endocytosis: a review of mechanisms and plasma membrane dynamics

    Endocytosis: a review of mechanisms and plasma membrane dynamics por Jeffrey M. Besterman, R B Low

    Publicado 1983
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  3. 3
    Rapid formation of diacylglycerol from phosphatidylcholine: a pathway for generation of a second messenger.

    Rapid formation of diacylglycerol from phosphatidylcholine: a pathway for generation of a second messenger. por Jeffrey M. Besterman, Vincent Duronio, Pedro Cuatrecasas

    Publicado 1986
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  4. 4
    Lack of association of epidermal growth factor-, insulin-, and serum-induced mitogenesis with stimulation of phosphoinositide degradation in BALB/c 3T3 fibroblasts.

    Lack of association of epidermal growth factor-, insulin-, and serum-induced mitogenesis with stimulation of phosphoinositide degradation in BALB/c 3T3 fibroblasts. por Jeffrey M. Besterman, Steve P. Watson, Pedro Cuatrecasas

    Publicado 1986
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  5. 5
    Diacylglycerol-induced translocation of diacylglycerol kinase: use of affinity-purified enzyme in a reconstitution system.

    Diacylglycerol-induced translocation of diacylglycerol kinase: use of affinity-purified enzyme in a reconstitution system. por Jeffrey M. Besterman, Richard S. Pollenz, E L Booker, Pedro Cuatrecasas

    Publicado 1986
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  6. 6
    Inhibition of epidermal growth factor-induced mitogenesis by amiloride and an analog: evidence against a requirement for Na+/H+ exchange.

    Inhibition of epidermal growth factor-induced mitogenesis by amiloride and an analog: evidence against a requirement for Na+/H+ exchange. por Jeffrey M. Besterman, Scott Tyrey, Edward J. Cragoe, Pedro Cuatrecasas

    Publicado 1984
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  7. 7
    Models of human metastatic colon cancer in nude mice orthotopically constructed by using histologically intact patient specimens.

    Models of human metastatic colon cancer in nude mice orthotopically constructed by using histologically intact patient specimens. por Xiuping Fu, Jeffrey M. Besterman, Anna Z. Monosov, Richard M. Hoffman

    Publicado 1991
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  8. 8
    Exocytosis of pinocytosed fluid in cultured cells: kinetic evidence for rapid turnover and compartmentation.

    Exocytosis of pinocytosed fluid in cultured cells: kinetic evidence for rapid turnover and compartmentation. por Jeffrey M. Besterman, Judith Airhart, Robert C. Woodworth, R B Low

    Publicado 1981
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  9. 9
    Down-regulation of Human DNA-(Cytosine-5) Methyltransferase Induces Cell Cycle Regulators p16 and p21WAF/Cip1 by Distinct Mechanisms

    Down-regulation of Human DNA-(Cytosine-5) Methyltransferase Induces Cell Cycle Regulators p16 and p21WAF/Cip1 by Distinct Mechanisms por Marielle Fournel, Przemysław Sapieha, Normand Beaulieu, Jeffrey M. Besterman, A. Robert MacLeod

    Publicado 1999
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  10. 10
    Amiloride inhibits phorbol ester-stimulated Na+/H+ exchange and protein kinase C. An amiloride analog selectively inhibits Na+/H+ exchange.

    Amiloride inhibits phorbol ester-stimulated Na+/H+ exchange and protein kinase C. An amiloride analog selectively inhibits Na+/H+ exchange. por Jeffrey M. Besterman, W. Stratford May, Harry LeVine, Edward J. Cragoe, Pedro Cuatrecasas

    Publicado 1985
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  11. 11
    Activity of MGCD290, a Hos2 Histone Deacetylase Inhibitor, in Combination with Azole Antifungals against Opportunistic Fungal Pathogens

    Activity of MGCD290, a Hos2 Histone Deacetylase Inhibitor, in Combination with Azole Antifungals against Opportunistic Fungal Pathogens por Michael A. Pfaller, S. A. Messer, N H Georgopapadakou, L. A. Martell, Jeffrey M. Besterman, Daniel J. Diekema

    Publicado 2009
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  12. 12
    Protein kinase C phosphorylates topoisomerase II: topoisomerase activation and its possible role in phorbol ester-induced differentiation of HL-60 cells.

    Protein kinase C phosphorylates topoisomerase II: topoisomerase activation and its possible role in phorbol ester-induced differentiation of HL-60 cells. por N Sahyoun, Marlene Wolf, Jeffrey M. Besterman, Tsung‐Cheng Hsieh, M Sander, Harry LeVine, Kwen‐Jen Chang, Pedro Cuatrecasas

    Publicado 1986
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  13. 13
    Mammalian DNA Ligase III: Molecular Cloning, Chromosomal Localization, and Expression in Spermatocytes Undergoing Meiotic Recombination

    Mammalian DNA Ligase III: Molecular Cloning, Chromosomal Localization, and Expression in Spermatocytes Undergoing Meiotic Recombination por Jingwen Chen, Alan E. Tomkinson, William Ramos, Zachary B. Mackey, Sue Danehower, Christi A. Walter, Roger A. Schultz, Jeffrey M. Besterman, Intisar Husain

    Publicado 1995
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  14. 14
    The class‐I HDAC inhibitor MGCD0103 induces apoptosis in Hodgkin lymphoma cell lines and synergizes with proteasome inhibitors by an HDAC6‐independent mechanism

    The class‐I HDAC inhibitor MGCD0103 induces apoptosis in Hodgkin lymphoma cell lines and synergizes with proteasome inhibitors by an HDAC6‐independent mechanism por Daniela Buglio, Vidya Mamidipudi, Noor M. Khaskhely, Helen Brady, Carla Heise, Jeffrey M. Besterman, Robert E. Martell, Kyle J. MacBeth, Anas Younes

    Publicado 2010
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  15. 15
    Evaluation of the Pharmacodynamic Effects of MGCD0103 from Preclinical Models to Human Using a Novel HDAC Enzyme Assay

    Evaluation of the Pharmacodynamic Effects of MGCD0103 from Preclinical Models to Human Using a Novel HDAC Enzyme Assay por Claire Bonfils, Ann Kalita, Marja Dubay, Lillian L. Siu, Michael A. Carducci, Gregory K. Reid, Robert E. Martell, Jeffrey M. Besterman, Zuomei Li

    Publicado 2008
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  16. 16
    A phase I pharmacokinetic and pharmacodynamic study of the DNA methyltransferase 1 inhibitor MG98 administered twice weekly

    A phase I pharmacokinetic and pharmacodynamic study of the DNA methyltransferase 1 inhibitor MG98 administered twice weekly por David J. Stewart, Ross C. Donehower, Elizabeth A. Eisenhauer, Nancy Wainman, Ajit Shah, Claire Bonfils, A. Robert MacLeod, Jeffrey M. Besterman, Gregory K. Reid

    Publicado 2003
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  17. 17
    Phase I Study of MGCD0103 Given As a Three-Times-Per-Week Oral Dose in Patients With Advanced Solid Tumors

    Phase I Study of MGCD0103 Given As a Three-Times-Per-Week Oral Dose in Patients With Advanced Solid Tumors por Lillian L. Siu, Роберто Пили, Ignacio Durán, Wells A. Messersmith, Eric X. Chen, Rana Sullivan, Martha MacLean, Serina King, Shirley Brown, Gregory K. Reid, Zuomei Li, Ann Kalita, Eric Laille, Jeffrey M. Besterman, Robert E. Martell, Michael A. Carducci

    Publicado 2008
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  18. 18
    Mocetinostat for relapsed classical Hodgkin's lymphoma: an open-label, single-arm, phase 2 trial

    Mocetinostat for relapsed classical Hodgkin's lymphoma: an open-label, single-arm, phase 2 trial por Anas Younes, Yasuhiro Oki, R. Gregory Bociek, John Kuruvilla, Michelle A. Fanale, Sattva S. Neelapu, Amanda Copeland, Daniela Buglio, Ahmed Galal, Jeffrey M. Besterman, Zuomei Li, Michel Drouin, Tracy Patterson, M. Renee Ward, Jessica K. Paulus, Yuan Ji, L. Jeffrey Medeiros, Robert E. Martell

    Publicado 2011
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  19. 19
    Phase 1 study of the oral isotype specific histone deacetylase inhibitor MGCD0103 in leukemia

    Phase 1 study of the oral isotype specific histone deacetylase inhibitor MGCD0103 in leukemia por Guillermo Garcia‐Manero, Sarit Assouline, Jorge E. Cortés, Zeev Estrov, Hagop M. Kantarjian, Hui Yang, Willie Newsome, Wilson H. Miller, Caroline Rousseau, Ann Kalita, Claire Bonfils, Marja Dubay, T. Patterson, Zuomei Li, Jeffrey M. Besterman, Gregory K. Reid, Eric Laille, Robert E. Martell, Mark D. Minden

    Publicado 2008
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  20. 20
    Phase I Study of MG98, an Oligonucleotide Antisense Inhibitor of Human DNA Methyltransferase 1, Given as a 7-Day Infusion in Patients with Advanced Solid Tumors

    Phase I Study of MG98, an Oligonucleotide Antisense Inhibitor of Human DNA Methyltransferase 1, Given as a 7-Day Infusion in Patients with Advanced Solid Tumors por Ruth Plummer, Laura Vidal, Martin Griffin, Mark Lesley, Johann S. de Bono, Sally A. Coulthard, Julieann Sludden, Lillian L. Siu, Eric X. Chen, Amit M. Oza, Gregory K. Reid, A. Robert McLeod, Jeffrey M. Besterman, Chooi Lee, Ian Judson, Hilary Calvert, Alan V. Boddy

    Publicado 2009
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