Search Results - Jean‐Philippe Defour

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  1. 1
    The Thrombopoietin Receptor: Structural Basis of Traffic and Activation by Ligand, Mutations, Agonists, and Mutated Calreticulin

    The Thrombopoietin Receptor: Structural Basis of Traffic and Activation by Ligand, Mutations, Agonists, and Mutated Calreticulin by Leila N. Varghese, Jean‐Philippe Defour, C. Pecquet, Stefan N. Constantinescu

    Published 2017
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  2. 2
    Adult haemophagocytic lymphohistiocytosis: a review

    Adult haemophagocytic lymphohistiocytosis: a review by Halil Yıldız, Eric Van Den Neste, Jean‐Philippe Defour, Étienne Danse, Jean Cyr Yombi

    Published 2020
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  3. 3
    What is the normal value of the neutrophil-to-lymphocyte ratio?

    What is the normal value of the neutrophil-to-lymphocyte ratio? by Patrice Forget, Céline Khalifa, Jean‐Philippe Defour, Dominique Latinne, Marie-Cécile Van Pel, Marc De Kock

    Published 2017
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  4. 4
    Tryptophan at the transmembrane–cytosolic junction modulates thrombopoietin receptor dimerization and activation

    Tryptophan at the transmembrane–cytosolic junction modulates thrombopoietin receptor dimerization and activation by Jean‐Philippe Defour, Miki Itaya, Vitalina Gryshkova, Ian Brett, C. Pecquet, Takeshi Sato, Steven O. Smith, Stefan N. Constantinescu

    Published 2013
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  5. 5
    Short telomeres increase the risk of severe COVID-19

    Short telomeres increase the risk of severe COVID-19 by Antoine Froidure, Manon Mahieu, Delphine Hoton, Pierre‐François Laterre, Jean Cyr Yombi, Sandra Koenig, Benoît Ghaye, Jean‐Philippe Defour, Anabelle Decottignies

    Published 2020
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  6. 6
    Orientation-specific signalling by thrombopoietin receptor dimers

    Orientation-specific signalling by thrombopoietin receptor dimers by Judith Staerk, Jean‐Philippe Defour, C. Pecquet, Emilie Leroy, Hélène Antoine‐Poirel, Ian Brett, Miki Itaya, Steven O. Smith, William Vainchenker, Stefan N. Constantinescu

    Published 2011
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  7. 7
    Failure to eliminate a phosphorylated glucose analog leads to neutropenia in patients with G6PT and G6PC3 deficiency

    Failure to eliminate a phosphorylated glucose analog leads to neutropenia in patients with G6PT and G6PC3 deficiency by Maria Veiga‐da‐Cunha, Nathalie Chevalier, Xavier Stéphenne, Jean‐Philippe Defour, Nicole Paczia, Alina Ferster, Younès Achouri, Joseph P. Dewulf, Carole L. Linster, Guido T. Bommer, Emile Van Schaftingen

    Published 2019
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  8. 8
    Knock-in of murine Calr del52 induces essential thrombocythemia with slow-rising dominance in mice and reveals key role of Calr exon 9 in cardiac development

    Knock-in of murine Calr del52 induces essential thrombocythemia with slow-rising dominance in mice and reveals key role of Calr exon 9 in cardiac development by Thomas Balligand, Younès Achouri, C. Pecquet, Gilles Gaudray, Didier Colau, Eva Hug, Yacine Rahmani, Vincent Stroobant, Isabelle Plo, William Vainchenker, Róbert Královics, Benoı̂t J. Van den Eynde, Jean‐Philippe Defour, Stefan N. Constantinescu

    Published 2019
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  9. 9
    Thrombopoietin receptor down-modulation by JAK2 V617F: restoration of receptor levels by inhibitors of pathologic JAK2 signaling and of proteasomes

    Thrombopoietin receptor down-modulation by JAK2 V617F: restoration of receptor levels by inhibitors of pathologic JAK2 signaling and of proteasomes by C. Pecquet, Carmen C. Diaconu, Judith Staerk, Michael Girardot, Caroline Marty, Yohan Royer, Jean‐Philippe Defour, Alexandra Dusa, Rodolphe Besancenot, Stéphane Giraudier, Jean‐Luc Villeval, Laurent Knoops, Pierre J. Courtoy, William Vainchenker, Stefan N. Constantinescu

    Published 2012
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  10. 10
    Combination treatment for myeloproliferative neoplasms using <scp>JAK</scp> and pan‐class I <scp>PI</scp>3K inhibitors

    Combination treatment for myeloproliferative neoplasms using <scp>JAK</scp> and pan‐class I <scp>PI</scp>3K inhibitors by Meng Ling Choong, C. Pecquet, Vishal Pendharkar, Carmen C. Diaconu, Jacklyn Wei Yan Yong, Shi Tai, Si Fang Wang, Jean‐Philippe Defour, Kanda Sangthongpitag, Jean‐Luc Villeval, William Vainchenker, Stefan N. Constantinescu, May Ann Lee

    Published 2013
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  11. 11
    Thrombopoietin receptor activation by myeloproliferative neoplasm associated calreticulin mutants

    Thrombopoietin receptor activation by myeloproliferative neoplasm associated calreticulin mutants by Ilyas Chachoua, C. Pecquet, Mira El-Khoury, Harini Nivarthi, Roxana-Irina Albu, Caroline Marty, Vitalina Gryshkova, Jean‐Philippe Defour, Gaëlle Vertenoeil, Anna Ngo, Ann Koay, Hana Raslová, Pierre J. Courtoy, Meng Ling Choong, Isabelle Plo, William Vainchenker, Róbert Královics, Stefan N. Constantinescu

    Published 2015
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  12. 12
    Calreticulin mutants as oncogenic rogue chaperones for TpoR and traffic-defective pathogenic TpoR mutants

    Calreticulin mutants as oncogenic rogue chaperones for TpoR and traffic-defective pathogenic TpoR mutants by C. Pecquet, Ilyas Chachoua, Anita Roy, Thomas Balligand, Gaëlle Vertenoeil, Emilie Leroy, Roxana-Irina Albu, Jean‐Philippe Defour, Harini Nivarthi, Eva Hug, Erica Xu, Yasmine Ould-Amer, Céline Mouton, Didier Colau, Didier Vertommen, Myat Marlar Shwe, Caroline Marty, Isabelle Plo, William Vainchenker, Róbert Královics, Stefan N. Constantinescu

    Published 2019
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  13. 13
    Presence of atypical thrombopoietin receptor (MPL) mutations in triple-negative essential thrombocythemia patients

    Presence of atypical thrombopoietin receptor (MPL) mutations in triple-negative essential thrombocythemia patients by Xénia Cabagnols, Fabrizia Favale, Florence Pasquier, Kahia Messaoudi, Jean‐Philippe Defour, Jean‐Christophe Ianotto, Christophe Marzac, J P Le Couedic, Nathalie Droin, Ilyas Chachoua, Rémi Favier, M’Boyba Diop, Valérie Ugo, Nicole Casadevall, Najet Debili, Hana Raslová, Christine Bellanné-Chantelot, Stefan N. Constantinescu, Olivier Bluteau, Isabelle Plo, William Vainchenker

    Published 2015
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  14. 14
    Differential association of calreticulin type 1 and type 2 mutations with myelofibrosis and essential thrombocytemia: relevance for disease evolution

    Differential association of calreticulin type 1 and type 2 mutations with myelofibrosis and essential thrombocytemia: relevance for disease evolution by Xénia Cabagnols, Jean‐Philippe Defour, Valérie Ugo, Jean‐Christophe Ianotto, Pascal Mossuz, Julie Mondet, François Girodon, Jean Alexandre, Olivier Mansier, Jean‐François Viallard, Éric Lippert, Anne Murati, Julien Mozziconacci, Pascale Saussoy, Marie-Christine Vekemans, L. Knoops, Florence Pasquier, Vincent Ribrag, Éric Solary, Isabelle Plo, Stefan N. Constantinescu, Nicole Casadevall, William Vainchenker, Christophe Marzac, Olivier Bluteau

    Published 2014
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