Søgeresultater - Jason M. Sheltzer

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  1. 1
    A Transcriptional and Metabolic Signature of Primary Aneuploidy Is Present in Chromosomally Unstable Cancer Cells and Informs Clinical Prognosis

    A Transcriptional and Metabolic Signature of Primary Aneuploidy Is Present in Chromosomally Unstable Cancer Cells and Informs Clinical Prognosis af Jason M. Sheltzer

    Udgivet 2013
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  2. 2
    Systematic identification of mutations and copy number alterations associated with cancer patient prognosis

    Systematic identification of mutations and copy number alterations associated with cancer patient prognosis af Joan C. Smith, Jason M. Sheltzer

    Udgivet 2018
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  3. 3
    Genome-wide identification and analysis of prognostic features in human cancers

    Genome-wide identification and analysis of prognostic features in human cancers af Joan C. Smith, Jason M. Sheltzer

    Udgivet 2022
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  4. 4
    Extensive protein dosage compensation in aneuploid human cancers

    Extensive protein dosage compensation in aneuploid human cancers af Klaske M. Schukken, Jason M. Sheltzer

    Udgivet 2022
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  5. 5
    Generating Single Cell–Derived Knockout Clones in Mammalian Cells with CRISPR/Cas9

    Generating Single Cell–Derived Knockout Clones in Mammalian Cells with CRISPR/Cas9 af Christopher J. Giuliano, Ann Lin, Vishruth Girish, Jason M. Sheltzer

    Udgivet 2019
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  6. 6
    Transcriptional consequences of aneuploidy

    Transcriptional consequences of aneuploidy af Jason M. Sheltzer, Eduardo M. Torres, Maitreya J. Dunham, Angelika Amon

    Udgivet 2012
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  7. 7
    Mitotic entry in the presence of DNA damage is a widespread property of aneuploidy in yeast

    Mitotic entry in the presence of DNA damage is a widespread property of aneuploidy in yeast af Heidi M. Blank, Jason M. Sheltzer, Colleen M. Meehl, Angelika Amon

    Udgivet 2015
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  8. 8
    CRISPR/Cas9 mutagenesis invalidates a putative cancer dependency targeted in on-going clinical trials

    CRISPR/Cas9 mutagenesis invalidates a putative cancer dependency targeted in on-going clinical trials af Ann Lin, Christopher J. Giuliano, Nicole M. Sayles, Jason M. Sheltzer

    Udgivet 2017
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  9. 9
    MELK expression correlates with tumor mitotic activity but is not required for cancer growth

    MELK expression correlates with tumor mitotic activity but is not required for cancer growth af Christopher J. Giuliano, Ann Lin, Joan C. Smith, Ann Palladino, Jason M. Sheltzer

    Udgivet 2018
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  10. 10
    Cigarette smoke exposure and inflammatory signaling increase the expression of the SARS-CoV-2 receptor ACE2 in the respiratory tract

    Cigarette smoke exposure and inflammatory signaling increase the expression of the SARS-CoV-2 receptor ACE2 in the respiratory tract af Joan C. Smith, Erin L. Sausville, Vishruth Girish, Monet Lou Yuan, Kristen M. John, Jason M. Sheltzer

    Udgivet 2020
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  11. 11
    Cigarette Smoke Exposure and Inflammatory Signaling Increase the Expression of the SARS-CoV-2 Receptor ACE2 in the Respiratory Tract

    Cigarette Smoke Exposure and Inflammatory Signaling Increase the Expression of the SARS-CoV-2 Receptor ACE2 in the Respiratory Tract af Joan C. Smith, Erin L. Sausville, Vishruth Girish, Monet Lou Yuan, Anand Vasudevan, Kristen M. John, Jason M. Sheltzer

    Udgivet 2020
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  12. 12
    Evolving copy number gains promote tumor expansion and bolster mutational diversification

    Evolving copy number gains promote tumor expansion and bolster mutational diversification af Zicheng Wang, Yunong Xia, Lauren Mills, Αθανάσιος Ν. Νικολακόπουλος, Nicole Maeser, Scott M. Dehm, Jason M. Sheltzer, Ruping Sun

    Udgivet 2024
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  13. 13
    Aneuploidy Drives Genomic Instability in Yeast

    Aneuploidy Drives Genomic Instability in Yeast af Jason M. Sheltzer, Heidi M. Blank, Sarah J. Pfau, Yoshie Tange, Benson M. George, Timothy J. Humpton, Ilana Brito, Yasushi Hiraoka, Osami Niwa, Angelika Amon

    Udgivet 2011
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  14. 14
    Single-chromosome Gains Commonly Function as Tumor Suppressors

    Single-chromosome Gains Commonly Function as Tumor Suppressors af Jason M. Sheltzer, Julie H. Ko, John Replogle, Nicole C. Habibe Burgos, Erica S. Chung, Colleen M. Meehl, Nicole M. Sayles, Verena Passerini, Zuzana Štorchová, Angelika Amon

    Udgivet 2017
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  15. 15
    Single-Chromosomal Gains Can Function as Metastasis Suppressors and Promoters in Colon Cancer

    Single-Chromosomal Gains Can Function as Metastasis Suppressors and Promoters in Colon Cancer af Anand Vasudevan, Prasamit Saurav Baruah, Joan C. Smith, Zihua Wang, Nicole M. Sayles, Peter Andrews, Jude Kendall, Justin Leu, Narendra Kumar Chunduri, Dan Levy, Michael Wigler, Zuzana Štorchová, Jason M. Sheltzer

    Udgivet 2020
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  16. 16
    Aneuploidy increases resistance to chemotherapeutics by antagonizing cell division

    Aneuploidy increases resistance to chemotherapeutics by antagonizing cell division af John Replogle, Wen Zhou, Adrianna E. Amaro, James M. McFarland, Mariana Villalobos-Ortiz, Jeremy Ryan, Anthony Letai, Ömer Yılmaz, Jason M. Sheltzer, Stephen J. Lippard, Uri Ben‐David, Angelika Amon

    Udgivet 2020
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  17. 17
    Chromosomal instability accelerates the evolution of resistance to anti-cancer therapies

    Chromosomal instability accelerates the evolution of resistance to anti-cancer therapies af Devon A. Lukow, Erin L. Sausville, Pavit Suri, Narendra Kumar Chunduri, Angela Wieland, Justin Leu, Joan C. Smith, Vishruth Girish, Ankith A. Kumar, Jude Kendall, Zihua Wang, Zuzana Štorchová, Jason M. Sheltzer

    Udgivet 2021
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  18. 18
    Off-target toxicity is a common mechanism of action of cancer drugs undergoing clinical trials

    Off-target toxicity is a common mechanism of action of cancer drugs undergoing clinical trials af Ann Lin, Christopher J. Giuliano, Ann Palladino, Kristen M. John, Connor Abramowicz, Monet Lou Yuan, Erin L. Sausville, Devon A. Lukow, Luwei Liu, Alexander R. Chait, Zachary Galluzzo, Clara Tucker, Jason M. Sheltzer

    Udgivet 2019
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  19. 19
    Micronuclei-based model system reveals functional consequences of chromothripsis in human cells

    Micronuclei-based model system reveals functional consequences of chromothripsis in human cells af Maja Kneissig, Kristina Keuper, Mirjam S. de Pagter, Markus J. van Roosmalen, Jana Martin, Hannah Otto, Verena Passerini, Aline Campos Sparr, Ivo Renkens, Fenna Kropveld, Anand Vasudevan, Jason M. Sheltzer, Wigard P. Kloosterman, Zuzana Štorchová

    Udgivet 2019
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  20. 20
    Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity

    Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity af Markus Hoffmann, Heike Hofmann-Winkler, Joan C. Smith, Nadine Krüger, Lambert K. Sørensen, Ole S. Søgaard, Jørgen B. Hasselstrøm, Michael Winkler, Tim Hempel, Lluı́s Raich, Simon Olsson, Takashi Yamazoe, Katsura Yamatsuta, Hirotaka Mizuno, Stephan Ludwig, Frank Noé, Jason M. Sheltzer, Mads Kjølby, Stefan Pöhlmann

    Udgivet 2020
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