Search Results - Jason E. Cain

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  1. 1
    Genetics of Renal Hypoplasia: Insights Into the Mechanisms Controlling Nephron Endowment

    Genetics of Renal Hypoplasia: Insights Into the Mechanisms Controlling Nephron Endowment by Jason E. Cain, Valeria Di Giovanni, Joanna Smeeton, Norman D. Rosenblum

    Published 2010
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  2. 2
    Hedgehog Signaling in the Maintenance of Cancer Stem Cells

    Hedgehog Signaling in the Maintenance of Cancer Stem Cells by Catherine R. Cochrane, Anette Szczepny, D. Neil Watkins, Jason E. Cain

    Published 2015
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  3. 3
    GLI3 repressor controls functional development of the mouse ureter

    GLI3 repressor controls functional development of the mouse ureter by Jason E. Cain, Epshita A. Islam, Fiona Haxho, Joshua Blake, Norman D. Rosenblum

    Published 2011
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  4. 4
    BMP Receptor ALK3 Controls Collecting System Development

    BMP Receptor ALK3 Controls Collecting System Development by Sunny Hartwig, Darren Bridgewater, Valeria Di Giovanni, Jason E. Cain, Yuji Mishina, Norman D. Rosenblum

    Published 2008
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  5. 5
    The degree of mitochondrial DNA methylation in tumor models of glioblastoma and osteosarcoma

    The degree of mitochondrial DNA methylation in tumor models of glioblastoma and osteosarcoma by Xin Sun, Vijesh Vaghjiani, W. Samantha N. Jayasekara, Jason E. Cain, Justin C. St. John

    Published 2018
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  6. 6
    GLI3 Repressor Controls Nephron Number via Regulation of Wnt11 and Ret in Ureteric Tip Cells

    GLI3 Repressor Controls Nephron Number via Regulation of Wnt11 and Ret in Ureteric Tip Cells by Jason E. Cain, Epshita A. Islam, Fiona Haxho, Lin Chen, Darren Bridgewater, Erica Nieuwenhuis, Chi‐chung Hui, Norman D. Rosenblum

    Published 2009
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  7. 7
    Preclinical Activity of Nanoliposomal Irinotecan Is Governed by Tumor Deposition and Intratumor Prodrug Conversion

    Preclinical Activity of Nanoliposomal Irinotecan Is Governed by Tumor Deposition and Intratumor Prodrug Conversion by Ashish Kalra, Jaeyeon Kim, Stephan G. Klinz, Nancy Paz, Jason E. Cain, Daryl C. Drummond, Ulrik B. Nielsen, Jonathan B. Fitzgerald

    Published 2014
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  8. 8
    Identification of fibroblast growth factor receptor 3 mutations in urine sediment DNA samples complements cytology in bladder tumor detection

    Identification of fibroblast growth factor receptor 3 mutations in urine sediment DNA samples complements cytology in bladder tumor detection by Kimberly Rieger‐Christ, Arthur Mourtzinos, Peter J. Lee, Ralph M. Zagha, Jason E. Cain, Mark L. Silverman, John A. Libertino, Ian C. Summerhayes

    Published 2003
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  9. 9
    Pharmaco-proteogenomic profiling of pediatric diffuse midline glioma to inform future treatment strategies

    Pharmaco-proteogenomic profiling of pediatric diffuse midline glioma to inform future treatment strategies by Izac J. Findlay, Geoffry N. De Iuliis, Ryan J. Duchatel, Evangeline R. Jackson, Nicholas A. Vitanza, Jason E. Cain, Sebastian M. Waszak, Matthew D. Dun

    Published 2021
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  10. 10
    Cre-dependent DNA recombination activates a STING-dependent innate immune response

    Cre-dependent DNA recombination activates a STING-dependent innate immune response by Geneviève Pépin, Jonathan Ferrand, Klara Höning, W. Samantha N. Jayasekara, Jason E. Cain, Mark A. Behlke, Daniel J. Gough, Bryan R.G. Williams, Veit Hornung, Michael P. Gantier

    Published 2016
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  11. 11
    Low-Dose Histone Deacetylase Inhibitor Treatment Leads to Tumor Growth Arrest and Multi-Lineage Differentiation of Malignant Rhabdoid Tumors

    Low-Dose Histone Deacetylase Inhibitor Treatment Leads to Tumor Growth Arrest and Multi-Lineage Differentiation of Malignant Rhabdoid Tumors by Andrea Muscat, Dean Popovski, W. Samantha N. Jayasekara, Fernando J. Rossello, Melissa Ferguson, Kieren D. Marini, Muhammad Alamgeer, Elizabeth M. Algar, Peter Downie, D. Neil Watkins, Jason E. Cain, David M. Ashley

    Published 2016
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  12. 12
    Topoisomerase 1 Inhibition Promotes Cyclic GMP-AMP Synthase-Dependent Antiviral Responses

    Topoisomerase 1 Inhibition Promotes Cyclic GMP-AMP Synthase-Dependent Antiviral Responses by Geneviève Pépin, Charlotte Nejad, Jonathan Ferrand, Belinda J. Thomas, H. James Stunden, Elaine Sanij, Chwan-Hong Foo, Cameron R. Stewart, Jason E. Cain, Philip G. Bardin, Bryan R.G. Williams, Michael P. Gantier

    Published 2017
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  13. 13
    MYC drives platinum resistant SCLC that is overcome by the dual PI3K-HDAC inhibitor fimepinostat

    MYC drives platinum resistant SCLC that is overcome by the dual PI3K-HDAC inhibitor fimepinostat by Jasmine Chen, Aleks C. Guanizo, W. Samantha N. Jakasekara, Chaitanya Inampudi, Quinton Luong, Daniel J. Garama, Muhammad Alamgeer, Nishant Thakur, Michael DeVeer, Vinod Ganju, D. Neil Watkins, Jason E. Cain, Daniel J. Gough

    Published 2023
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  14. 14
    The role of canonical and non-canonical Hedgehog signaling in tumor progression in a mouse model of small cell lung cancer

    The role of canonical and non-canonical Hedgehog signaling in tumor progression in a mouse model of small cell lung cancer by Anette Szczepny, Samuel Rogers, W. Samantha N. Jayasekara, Kwon-Sik Park, Rachael A. McCloy, Catherine R. Cochrane, Vinod Ganju, Wendy A. Cooper, Julien Sage, Craig D. Peacock, Jason E. Cain, Andrew Burgess, D. Neil Watkins

    Published 2017
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  15. 15
    Correlation between Ferumoxytol Uptake in Tumor Lesions by MRI and Response to Nanoliposomal Irinotecan in Patients with Advanced Solid Tumors: A Pilot Study

    Correlation between Ferumoxytol Uptake in Tumor Lesions by MRI and Response to Nanoliposomal Irinotecan in Patients with Advanced Solid Tumors: A Pilot Study by Ramesh K. Ramanathan, Ronald L. Korn, Natarajan Raghunand, Jasgit C. Sachdev, Ronald G. Newbold, Gayle Jameson, Gerald J. Fetterly, Joshua Prey, Stephan G. Klinz, Jaeyeon Kim, Jason E. Cain, Bart S. Hendriks, Daryl C. Drummond, Eliel Bayever, Jonathan B. Fitzgerald

    Published 2017
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  16. 16
    Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing

    Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing by Chae Ho Lim, Qi Sun, Karan Ratti, Soung-Hoon Lee, Ying Zheng, Makoto Takeo, Wendy Lee, Piul S. Rabbani, Maksim V. Plikus, Jason E. Cain, David H. Wang, D. Neil Watkins, Sarah E. Millar, M. Mark Taketo, Peggy Myung, George Cotsarelis, Mayumi Ito

    Published 2018
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  17. 17
    <scp>ADAM</scp> 17 selectively activates the <scp>IL</scp> ‐6 trans‐signaling/ <scp>ERK MAPK</scp> axis in <scp>KRAS</scp> ‐addicted lung cancer

    <scp>ADAM</scp> 17 selectively activates the <scp>IL</scp> ‐6 trans‐signaling/ <scp>ERK MAPK</scp> axis in <scp>KRAS</scp> ‐addicted lung cancer by Mohamed I. Saad, Sultan Alhayyani, Louise McLeod, Yu Liang, Mohammad Alanazi, Virginie Deswaerte, Ke Tang, Thierry Jardé, Julian A. Smith, Zdenka Prodanovic, Michelle D. Tate, Jesse J. Balic, D. Neil Watkins, Jason E. Cain, Steven Bozinovski, Elizabeth M. Algar, Tomohiro Kohmoto, Hiromichi Ebi, Walter Ferlin, Christoph Garbers, Saleela M. Ruwanpura, Irit Sagi, Stefan Rose‐John, Brendan J. Jenkins

    Published 2019
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  18. 18
    Imipridones affect tumor bioenergetics and promote cell lineage differentiation in diffuse midline gliomas

    Imipridones affect tumor bioenergetics and promote cell lineage differentiation in diffuse midline gliomas by Justyna M. Przystal, Chiara Cosentino, Sridevi Yadavilli, Jie Zhang, Sandra Laternser, Erin R. Bonner, Rachna Prasad, Adam Dawood, Nina Lobeto, Wai Chin Chong, Matthew C. Biery, Carrie Myers, James M. Olson, Eshini Panditharatna, Bettina Kritzer, Sulayman Mourabit, Nicholas A. Vitanza, Mariella G. Filbin, Geoffry N. De Iuliis, Matthew D. Dun, Carl Koschmann, Jason E. Cain, Michael Grotzer, Sebastian M. Waszak, Sabine Mueller, Javad Nazarian

    Published 2022
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  19. 19
    Preclinical and clinical evaluation of German-sourced ONC201 for the treatment of H3K27M-mutant diffuse intrinsic pontine glioma

    Preclinical and clinical evaluation of German-sourced ONC201 for the treatment of H3K27M-mutant diffuse intrinsic pontine glioma by Ryan J. Duchatel, Abdul Mannan, Ameha Seyoum Woldu, Tom Hawtrey, Phoebe A Hindley, Alicia M. Douglas, Evangeline R. Jackson, Izac J. Findlay, Zacary P. Germon, Dilana E. Staudt, Padraic S. Kearney, Nathan D. Smith, Kate E Hindley, Jason E. Cain, Nicolás André, Andrés Morales La Madrid, Brett Nixon, Geoffry N. De Iuliis, Javad Nazarian, Kathleen Irish, Frank Alvaro, David D. Eisenstat, Alexander Beck, Nicholas A. Vitanza, Sabine Mueller, Jonathan C. Morris, Matthew D. Dun

    Published 2021
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  20. 20
    Inhibition of activin signaling in lung adenocarcinoma increases the therapeutic index of platinum chemotherapy

    Inhibition of activin signaling in lung adenocarcinoma increases the therapeutic index of platinum chemotherapy by Kieren D. Marini, David R. Croucher, Rachael A. McCloy, Vijesh Vaghjiani, Álvaro González-Rajal, Jordan F. Hastings, Venessa Chin, Anette Szczepny, Kaja Kostyrko, César Márquez, W. Samantha N. Jayasekara, Muhammad Alamgeer, Vishal Boolell, Jeremy Z. R. Han, Todd Waugh, Hong Ching Lee, Samantha R. Oakes, Beena Kumar, Craig A. Harrison, Mark P. Hedger, Nirmal Lorensuhewa, Badia Kita, Ross Barrow, Bruce Robinson, David M. de Kretser, Jianmin Wu, Vinod Ganju, E. Alejandro Sweet‐Cordero, Andrew Burgess, Luciano G. Martelotto, Fernando J. Rossello, Jason E. Cain, D. Neil Watkins

    Published 2018
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