Resultados de búsqueda - Jared Head
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1
Ability of Bruton’s Tyrosine Kinase Inhibitors to Sequester Y551 and Prevent Phosphorylation Determines Potency for Inhibition of Fc Receptor but not B-Cell Receptor Signaling por Andrew T. Bender, A.S. Gardberg, Albertina Pereira, Theresa Johnson, Yin Wu, Roland Grenningloh, Jared Head, Federica Morandi, Philipp Haselmayer, Lesley Liu‐Bujalski
Publicado 2017Artigo -
2
Efficacy and Pharmacodynamic Modeling of the BTK Inhibitor Evobrutinib in Autoimmune Disease Models por Philipp Haselmayer, Montserrat Camps, Lesley Liu‐Bujalski, Ngan Nguyen, Federica Morandi, Jared Head, Alison O’Mahony, Simone C. Zimmerli, Lisa Bruns, Andrew T. Bender, Patricia Schroeder, Roland Grenningloh
Publicado 2019Artigo -
3
Btk inhibition treats TLR7/IFN driven murine lupus por Andrew T. Bender, Albertina Pereira, Kai Fu, Eileen T. Samy, Yin Wu, Lesley Liu‐Bujalski, Richard D. Caldwell, Yi‐Ying Chen, Hui Tian, Federica Morandi, Jared Head, Ursula Koehler, Melinda Genest, Shinji L. Okitsu, Daigen Xu, Roland Grenningloh
Publicado 2016Artigo -
4
Discovery of Evobrutinib: An Oral, Potent, and Highly Selective, Covalent Bruton’s Tyrosine Kinase (BTK) Inhibitor for the Treatment of Immunological Diseases por Richard D. Caldwell, Hui Qiu, Ben Askew, Andrew T. Bender, Nadia Brügger, Montserrat Camps, Mohanraj Dhanabal, Vikram Dutt, Thomas Eichhorn, A.S. Gardberg, Andreas Goutopoulos, Roland Grenningloh, Jared Head, Brian Healey, Brian L. Hodous, Bayard R. Huck, Theresa Johnson, Christopher C. Jones, Reinaldo Jones, Igor Mochalkin, Federica Morandi, Thi Kim Ngan Nguyen, Michael Meyring, Justin R. Potnick, Dusica Santos, Ralf Schmidt, Brian Sherer, Adam Shutes, Klaus Urbahns, Ariele Viacava Follis, Ansgar Wegener, Simone C. Zimmerli, Lesley Liu‐Bujalski
Publicado 2019Artigo
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Materias Relacionadas
Bruton's tyrosine kinase
Tyrosine kinase
Biology
Immunology
Medicine
Pharmacology
Receptor
Biochemistry
Cancer research
Chemistry
Disease
Internal medicine
Signal transduction
Antibody
Autoantibody
Autoimmune disease
Autoimmunity
Cell biology
Chronic lymphocytic leukemia
Computational biology
Ibrutinib
Immune system
In vitro
Innate immune system
Kinase
Leukemia
Lupus nephritis
Pharmacodynamics
Pharmacokinetics
Phosphorylation