检索结果 - Janine Kirby
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Genetics of Familial Amyotrophic Lateral Sclerosis 由 Feneberg Emily, J. Joanna, Johnathan Cooper‐Knock, J. Pamela, Janine Kirby
出版 2012Capítulo de Livro -
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Lysosomal and phagocytic activity is increased in astrocytes during disease progression in the SOD1 G93A mouse model of amyotrophic lateral sclerosis 由 David Baker, D. Blackburn, Marcus Keatinge, Dilraj Sokhi, Paulius Viskaitis, Paul R. Heath, Laura Ferraiuolo, Janine Kirby, Pamela J. Shaw
出版 2015Artigo -
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Analysis of the Cytosolic Proteome in a Cell Culture Model of Familial Amyotrophic Lateral Sclerosis Reveals Alterations to the Proteasome, Antioxidant Defenses, and Nitric Oxide S... 由 Simon Allen, Paul R. Heath, Janine Kirby, Stephen B. Wharton, Mark Cookson, Fiona M. Menzies, Rosamonde E. Banks, Pamela J. Shaw
出版 2003Artigo -
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Simultaneous and independent detection of C9ORF72 alleles with low and high number of GGGGCC repeats using an optimised protocol of Southern blot hybridisation 由 Vladimir L. Buchman, Johnathan Cooper‐Knock, Natalie Connor‐Robson, Adrian Higginbottom, Janine Kirby, O D Razinskaya, Natalia Ninkina, Pamela J. Shaw
出版 2013Artigo -
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Unravelling the enigma of selective vulnerability in neurodegeneration: motor neurons resistant to degeneration in ALS show distinct gene expression characteristics and decreased s... 由 Alice Brockington, Ke Ning, Paul R. Heath, Elizabeth Wood, Janine Kirby, Nicolò Fusi, Neil D. Lawrence, Stephen B. Wharton, Paul G. Ince, Pamela J. Shaw
出版 2012Artigo -
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Antisense RNA foci in the motor neurons of C9ORF72-ALS patients are associated with TDP-43 proteinopathy 由 Johnathan Cooper‐Knock, Adrian Higginbottom, Matthew J. Stopford, J. Robin Highley, Paul G. Ince, Stephen B. Wharton, Stuart Pickering‐Brown, Janine Kirby, Guillaume M. Hautbergue, Pamela J. Shaw
出版 2015Artigo -
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C9ORF72 GGGGCC Expanded Repeats Produce Splicing Dysregulation which Correlates with Disease Severity in Amyotrophic Lateral Sclerosis 由 Johnathan Cooper‐Knock, Joanna J. Bury, Paul R. Heath, Matthew Wyles, Adrian Higginbottom, Catherine Gelsthorpe, J. Robin Highley, Guillaume M. Hautbergue, Magnus Rattray, Janine Kirby, Pamela J. Shaw
出版 2015Artigo -
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S[+] Apomorphine is a CNS penetrating activator of the Nrf2-ARE pathway with activity in mouse and patient fibroblast models of amyotrophic lateral sclerosis 由 Richard J. Mead, Adrian Higginbottom, Scott P. Allen, Janine Kirby, Ellen Bennett, Siân C. Barber, Paul R. Heath, Antonio Coluccia, Neelam Patel, Iain Gardner, Andrea Brancale, Andrew J. Grierson, Pamela J. Shaw
出版 2013Artigo
相关主题
Medicine
Amyotrophic lateral sclerosis
Biology
Disease
Gene
Genetics
Pathology
Neuroscience
C9orf72
Dementia
Frontotemporal dementia
Internal medicine
Allele
Trinucleotide repeat expansion
Cell biology
Gene expression
Phenotype
SOD1
Motor neuron
Neurodegeneration
Spinal cord
Immunology
Mutation
Bioinformatics
Mutant
Biochemistry
Central nervous system
Chemistry
Computational biology
Molecular biology