検索結果 - Janeta Popovici-Müller

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  1. 1
    Biochemical, Cellular, and Biophysical Characterization of a Potent Inhibitor of Mutant Isocitrate Dehydrogenase IDH1

    Biochemical, Cellular, and Biophysical Characterization of a Potent Inhibitor of Mutant Isocitrate Dehydrogenase IDH1 著者: Mindy I. Davis, Stefan Größ, Min Shen, Kimberly Straley, Rajan Pragani, Wendy Lea, Janeta Popovici-Müller, Byron DeLaBarre, Erin Artin, Natasha Thorne, Douglas S. Auld, Zhuyin Li, Lenny Dang, Matthew B. Boxer, Anton Simeonov

    出版事項 2014
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    Artigo
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  2. 2
    Structure and inhibition mechanism of the catalytic domain of human squalene epoxidase

    Structure and inhibition mechanism of the catalytic domain of human squalene epoxidase 著者: Anil K. Padyana, Stefan Größ, Lei Jin, Giovanni Cianchetta, Rohini Narayanaswamy, Feng Wang, Rui Wang, Fang Cheng, Xiaobing Lv, Scott A. Biller, Lenny Dang, Christopher E. Mahoney, N. Nagaraja, David Pirman, Zhihua Sui, Janeta Popovici-Müller, Gromoslaw A. Smolen

    出版事項 2019
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    Artigo
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  3. 3
    Discovery of the First Potent Inhibitors of Mutant IDH1 That Lower Tumor 2-HG <i>in Vivo</i>

    Discovery of the First Potent Inhibitors of Mutant IDH1 That Lower Tumor 2-HG <i>in Vivo</i> 著者: Janeta Popovici-Müller, Jeffrey O. Saunders, Francesco G. Salituro, Jeremy Travins, Shunqi Yan, Fang Zhao, Stefan Größ, Lenny Dang, Katharine Yen, Hua Yang, Kimberly Straley, Shengfang Jin, Kaiko Kunii, Valeria R. Fantin, Shunan Zhang, Qiongqun Pan, Derek Shi, Scott A. Biller, Shinsan M. Su

    出版事項 2012
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    Artigo
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  4. 4
    AG-348 enhances pyruvate kinase activity in red blood cells from patients with pyruvate kinase deficiency

    AG-348 enhances pyruvate kinase activity in red blood cells from patients with pyruvate kinase deficiency 著者: Charles Kung, Jeff Hixon, Penelope A. Kosinski, Giovanni Cianchetta, Gavin Histen, Yue Chen, Collin Hill, Stefan Größ, Yaguang Si, Kendall Johnson, Byron DeLaBarre, Zhiyong Luo, Zhiwei Gu, Gui Lan Yao, Huachun Tang, Cheng Fang, YingXia Xu, Xiaobing Lv, Scott A. Biller, Shinsan M. Su, Hua Yang, Janeta Popovici-Müller, Francesco G. Salituro, Lee Silverman, Lenny Dang

    出版事項 2017
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    Artigo
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  5. 5
    Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer

    Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer 著者: Supriya K. Saha, Christine A. Parachoniak, Krishna S. Ghanta, Julien Fitamant, Kenneth N. Ross, Mortada S. Najem, Sushma Gurumurthy, Esra A. Akbay, Daniela Sia, Helena Cornellà, Oriana Miltiadous, Chad Walesky, Vikram Deshpande, Andrew X. Zhu, Aram F. Hezel, Katharine Yen, Kimberly Straley, Jeremy Travins, Janeta Popovici-Müller, Camelia Gliser, Cristina R. Ferrone, Udayan Apte, Josep M. Llovet, Kwok‐Kin Wong, Sridhar Ramaswamy, Nabeel Bardeesy

    出版事項 2014
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    Artigo
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  6. 6
    An Inhibitor of Mutant IDH1 Delays Growth and Promotes Differentiation of Glioma Cells

    An Inhibitor of Mutant IDH1 Delays Growth and Promotes Differentiation of Glioma Cells 著者: Dan Rohle, Janeta Popovici-Müller, Nicolaos Palaskas, Şevin Turcan, Christian Grommes, Carl Campos, Jennifer Tsoi, Owen Clark, Barbara Oldrini, Evangelia Komisopoulou, Kaiko Kunii, Alicia Pedraza, Stefanie S. Schalm, Lee Silverman, Alexandra Miller, Fang Wang, Hua Yang, Yue Chen, Andrew Kernytsky, Marc K. Rosenblum, Wei Liu, Scott A. Biller, Shinsan M. Su, Cameron Brennan, Timothy A. Chan, Thomas G. Graeber, Katharine Yen, Ingo K. Mellinghoff

    出版事項 2013
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    Artigo
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  7. 7
    Vorasidenib (AG-881): A First-in-Class, Brain-Penetrant Dual Inhibitor of Mutant IDH1 and 2 for Treatment of Glioma

    Vorasidenib (AG-881): A First-in-Class, Brain-Penetrant Dual Inhibitor of Mutant IDH1 and 2 for Treatment of Glioma 著者: Zenon Konteatis, Erin Artin, Brandon Nicolay, Kimberly Straley, Anil K. Padyana, Lei Jin, Yue Chen, Rohini Narayaraswamy, Shuilong Tong, Feng Wang, Ding Zhou, Dawei Cui, Zhen‐Wei Cai, Zhiyong Luo, Cheng Fang, Huachun Tang, Xiaobing Lv, Raj Nagaraja, Hua Yang, Shinsan M. Su, Zhihua Sui, Lenny Dang, Katharine Yen, Janeta Popovici-Müller, Paolo Codega, Carl Campos, Ingo K. Mellinghoff, Scott A. Biller

    出版事項 2020
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    Artigo
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  8. 8
    A chemical biology screen identifies a vulnerability of neuroendocrine cancer cells to SQLE inhibition

    A chemical biology screen identifies a vulnerability of neuroendocrine cancer cells to SQLE inhibition 著者: Christopher E. Mahoney, David Pirman, Victor Chubukov, Taryn Sleger, Sebastian Hayes, Zi Peng Fan, Eric L. Allen, Ying Chen, Lingling Huang, Meina Liu, Yingjia Zhang, Gabrielle McDonald, Rohini Narayanaswamy, Sung Choe, Yue Chen, Stefan Größ, Giovanni Cianchetta, Anil K. Padyana, Stuart Murray, Wei Liu, Kevin M. Marks, Joshua Murtie, Marion Dorsch, Shengfang Jin, N. Nagaraja, Scott A. Biller, Thomas P. Roddy, Janeta Popovici-Müller, Gromoslaw A. Smolen

    出版事項 2019
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    Artigo
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  9. 9
    Discovery of AG-120 (Ivosidenib): A First-in-Class Mutant IDH1 Inhibitor for the Treatment of IDH1 Mutant Cancers

    Discovery of AG-120 (Ivosidenib): A First-in-Class Mutant IDH1 Inhibitor for the Treatment of IDH1 Mutant Cancers 著者: Janeta Popovici-Müller, René M. Lemieux, Erin Artin, Jeffrey O. Saunders, Francesco G. Salituro, Jeremy Travins, Giovanni Cianchetta, Zhen‐Wei Cai, Ding Zhou, Dawei Cui, Ping Chen, Kimberly Straley, Erica R. Tobin, Fang Wang, Muriel D. David, Virginie Penard‐Lacronique, Cyril Quivoron, Véronique Saada, Stéphane de Botton, Stefan Größ, Lenny Dang, Hua Yang, Luke Utley, Yue Chen, Hyeryun Kim, Shengfang Jin, Zhiwei Gu, Yao Gui, Zhiyong Luo, Xiaobing Lv, Cheng Fang, Liping Yan, Andrew Olaharski, Lee Silverman, Scott A. Biller, Shinsan M. Su, Katharine Yen

    出版事項 2018
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    Artigo
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