Suchergebnisse - Jan Gruber

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  1. 1
    The mitochondrial free radical theory of ageing - Where do we stand?

    The mitochondrial free radical theory of ageing - Where do we stand? von Jan Gruber

    Veröffentlicht 2008
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  2. 2
    Developmental Drift and the Role of Wnt Signaling in Aging

    Developmental Drift and the Role of Wnt Signaling in Aging von Jan Gruber, Zhuangli Yee, Nicholas S. Tolwinski

    Veröffentlicht 2016
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  3. 3
    Context-Dependent Role of Mitochondrial Fusion-Fission in Clonal Expansion of mtDNA Mutations

    Context-Dependent Role of Mitochondrial Fusion-Fission in Clonal Expansion of mtDNA Mutations von Zhi Yang Tam, Jan Gruber, Barry Halliwell, Rudiyanto Gunawan

    Veröffentlicht 2015
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  4. 4
    Deceptively simple but simply deceptive – <i>Caenorhabditis elegans</i> lifespan studies: Considerations for aging and antioxidant effects

    Deceptively simple but simply deceptive – <i>Caenorhabditis elegans</i> lifespan studies: Considerations for aging and antioxidant effects von Jan Gruber, Li Fang Ng, Suresh Poovathingal, Barry Halliwell

    Veröffentlicht 2009
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  5. 5
    Mathematical Modeling of the Role of Mitochondrial Fusion and Fission in Mitochondrial DNA Maintenance

    Mathematical Modeling of the Role of Mitochondrial Fusion and Fission in Mitochondrial DNA Maintenance von Zhi Yang Tam, Jan Gruber, Barry Halliwell, Rudiyanto Gunawan

    Veröffentlicht 2013
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  6. 6
    Effects of Lithium on Age-related Decline in Mitochondrial Turnover and Function in Caenorhabditis elegans

    Effects of Lithium on Age-related Decline in Mitochondrial Turnover and Function in Caenorhabditis elegans von Zhi Yang Tam, Jan Gruber, Lisa F. P. Ng, Barry Halliwell, Rudiyanto Gunawan

    Veröffentlicht 2014
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  7. 7
    A concerted increase in readthrough and intron retention drives transposon expression during aging and senescence

    A concerted increase in readthrough and intron retention drives transposon expression during aging and senescence von Kamil Pabis, Diogo Barardo, Olga Sirbu, Kumar Selvarajoo, Jan Gruber, Brian K. Kennedy

    Veröffentlicht 2024
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  8. 8
    Clonal expansion of mitochondrial DNA deletions is a private mechanism of aging in long‐lived animals

    Clonal expansion of mitochondrial DNA deletions is a private mechanism of aging in long‐lived animals von Lakshmi Narayanan Lakshmanan, Zhuangli Yee, Li Fang Ng, Rudiyanto Gunawan, Barry Halliwell, Jan Gruber

    Veröffentlicht 2018
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  9. 9
    Principal component-based clinical aging clocks identify signatures of healthy aging and targets for clinical intervention

    Principal component-based clinical aging clocks identify signatures of healthy aging and targets for clinical intervention von Sheng Fong, Kamil Pabis, Djakim Latumalea, Nomuundari Dugersuren, Maximilian Unfried, Nicholas S. Tolwinski, Brian K. Kennedy, Jan Gruber

    Veröffentlicht 2024
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  10. 10
    WNT Signaling in Disease

    WNT Signaling in Disease von NG Li, Prameet Kaur, Nawat Bunnag, Jahnavi Suresh, Isabelle Chiao Han Sung, Qian Tan, Jan Gruber, Nicholas S. Tolwinski

    Veröffentlicht 2019
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  11. 11
    Application of optogenetic Amyloid-β distinguishes between metabolic and physical damages in neurodegeneration

    Application of optogenetic Amyloid-β distinguishes between metabolic and physical damages in neurodegeneration von Chu Hsien Lim, Prameet Kaur, Emelyne Teo, Vanessa Yuk Man Lam, Fangchen Zhu, Caroline Kibat, Jan Gruber, Ajay S. Mathuru, Nicholas S. Tolwinski

    Veröffentlicht 2020
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  12. 12
    Energy crisis precedes global metabolic failure in a novel Caenorhabditis elegans Alzheimer Disease model

    Energy crisis precedes global metabolic failure in a novel Caenorhabditis elegans Alzheimer Disease model von Sheng Fong, Emelyne Teo, Li Fang Ng, Ce-Belle Chen, Lakshmi Narayanan Lakshmanan, Sau Yee Tsoi, Philip K. Moore, Takao Inoue, Barry Halliwell, Jan Gruber

    Veröffentlicht 2016
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  13. 13
    Inhibition of amyloid‐induced toxicity by ergothioneine in a transgenic <i>Caenorhabditis elegans</i> model

    Inhibition of amyloid‐induced toxicity by ergothioneine in a transgenic <i>Caenorhabditis elegans</i> model von Irwin K. Cheah, Li‐Theng Ng, Li‐Fang Ng, Vanessa Yuk Man Lam, Jan Gruber, Cheryl Huang, Fang‐Qin Goh, Keith H.C. Lim, Barry Halliwell

    Veröffentlicht 2019
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  14. 14
    Drug Synergy Slows Aging and Improves Healthspan through IGF and SREBP Lipid Signaling

    Drug Synergy Slows Aging and Improves Healthspan through IGF and SREBP Lipid Signaling von Tesfahun Dessale Admasu, Krishna Chaithanya Batchu, Diogo Barardo, Li Fang Ng, Vanessa Yuk Man Lam, Linfan Xiao, Amaury Cazenave‐Gassiot, Markus R. Wenk, Nicholas S. Tolwinski, Jan Gruber

    Veröffentlicht 2018
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  15. 15
    Mitochondrial Changes in Ageing Caenorhabditis elegans – What Do We Learn from Superoxide Dismutase Knockouts?

    Mitochondrial Changes in Ageing Caenorhabditis elegans – What Do We Learn from Superoxide Dismutase Knockouts? von Jan Gruber, Li Fang Ng, Sheng Fong, Yee Ting Wong, Soon Ann Koh, Ce-Belle Chen, Guanghou Shui, Wei Fun Cheong, Sebastian Schaffer, Markus R. Wenk, Barry Halliwell

    Veröffentlicht 2011
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  16. 16
    Hydrogen Sulfide Is an Endogenous Regulator of Aging in <i>Caenorhabditis elegans</i>

    Hydrogen Sulfide Is an Endogenous Regulator of Aging in <i>Caenorhabditis elegans</i> von Bedoor Qabazard, Ling Li, Jan Gruber, Meng Teng Peh, Li Fang Ng, Dinesh Kumar Srinivasan, Peter Rose, Choon‐Hong Tan, Brian Dymock, Feng Wei, Sarat Chandra Swain, Barry Halliwell, Stephen R. Stürzenbaum, Philip K. Moore

    Veröffentlicht 2013
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  17. 17
    Metabolic stress is a primary pathogenic event in transgenic Caenorhabditis elegans expressing pan-neuronal human amyloid beta

    Metabolic stress is a primary pathogenic event in transgenic Caenorhabditis elegans expressing pan-neuronal human amyloid beta von Emelyne Teo, Sudharshan Ravi, Diogo Barardo, Hyung-Seok Kim, Sheng Fong, Amaury Cazenave‐Gassiot, Tsze Yin Tan, Jianhong Ching, Jean‐Paul Kovalik, Markus R. Wenk, Rudiyanto Gunawan, Philip K. Moore, Barry Halliwell, Nicholas S. Tolwinski, Jan Gruber

    Veröffentlicht 2019
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  18. 18
    The DrugAge database of aging-related drugs

    The DrugAge database of aging-related drugs von Diogo Barardo, Daniel Thornton, Harikrishnan Thoppil, Michael Walsh, Samim Sharifi, Susana Isabel Ferreira, Andreja Anžič, Maria Fernandes, Patrick Monteiro, Tjaša Grum, Rui Cordeiro, Evandro A. De‐Souza, Arie Budovsky, Natali Araujo, Jan Gruber, Michael Petrascheck, Vadim E. Fraifeld, Alex Zhavoronkov, Alexey Moskalev, João Pedro de Magalhães

    Veröffentlicht 2017
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