Søgeresultater - Jan Gronych

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  1. 1
    MAPK pathway activation in pilocytic astrocytoma

    MAPK pathway activation in pilocytic astrocytoma af David Jones, Jan Gronych, Peter Lichter, Olaf Witt, Stefan M. Pfister

    Udgivet 2011
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  2. 2
    An activated mutant BRAF kinase domain is sufficient to induce pilocytic astrocytoma in mice

    An activated mutant BRAF kinase domain is sufficient to induce pilocytic astrocytoma in mice af Jan Gronych, Andrey Korshunov, Josephine Bageritz, Till Milde, Manfred Jugold, Dolores Hambardzumyan, Marc Remke, Christian Hartmann, Hendrik Witt, David Jones, Olaf Witt, Sabine Heiland, Martin Bendszus, Eric C. Holland, Stefan M. Pfister, Peter Lichter

    Udgivet 2011
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    Artigo
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  3. 3
    Targeting Self-Renewal in High-Grade Brain Tumors Leads to Loss of Brain Tumor Stem Cells and Prolonged Survival

    Targeting Self-Renewal in High-Grade Brain Tumors Leads to Loss of Brain Tumor Stem Cells and Prolonged Survival af Zhe Zhu, Muhammad Amir Khan, Markus Weiler, Jonas Blaes, Leonie Jestaedt, Madeleine Geibert, Peng Zou, Jan Gronych, Olga Bernhardt, Andrey Korshunov, Verena Bugner, Peter Lichter, Bernhard Radlwimmer, Sabine Heiland, Martin Bendszus, Wolfgang Wick, Hai‐Kun Liu

    Udgivet 2014
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    Artigo
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  4. 4
    Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling

    Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling af Marc Zuckermann, Volker Hovestadt, Christiane B. Knobbe‐Thomsen, Marc Zapatka, Paul A. Northcott, Kathrin Schramm, Jelena Belic, David Jones, Barbara R. Tschida, Branden S. Moriarity, David A. Largaespada, Martine F. Roussel, Andrey Korshunov, Guido Reifenberger, Stefan M. Pfister, Peter Lichter, Daisuke Kawauchi, Jan Gronych

    Udgivet 2015
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    Artigo
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  5. 5
    Novel MYC-driven medulloblastoma models from multiple embryonic cerebellar cells

    Novel MYC-driven medulloblastoma models from multiple embryonic cerebellar cells af Daisuke Kawauchi, Robert J. Ogg, Liang-Tseng Liu, David Shih, David Finkelstein, Brian L. Murphy, Jerold E. Rehg, Andrey Korshunov, Christopher Calabrese, Frédérique Zindy, Timothy N. Phoenix, Yoshiya Kawaguchi, Jan Gronych, Richard J. Gilbertson, Peter Lichter, Amar Gajjar, Marcel Kool, Paul A. Northcott, Stefan M. Pfister, Martine F. Roussel

    Udgivet 2017
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    Artigo
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  6. 6
    Establishment and application of a novel patient-derived KIAA1549:BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing

    Establishment and application of a novel patient-derived KIAA1549:BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing af Florian Selt, Juliane Hohloch, Thomas Hielscher, Felix Sahm, David Capper, Andrey Korshunov, Diren Usta, Sebastian Brabetz, Johannes Ridinger, Jonas Ecker, Ina Oehme, Jan Gronych, Viktoria Marquardt, David Pauck, Heidi Bächli, Charles D. Stiles, Andreas von Deimling, Marc Remke, Martin U. Schuhmann, Stefan M. Pfister, Tilman Brummer, David Jones, Olaf Witt, Till Milde

    Udgivet 2016
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    Artigo
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  7. 7
    Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme

    Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme af Weijun Feng, Daisuke Kawauchi, Huiqin Körkel-Qu, Huan Deng, Elisabeth Serger, Laura Sieber, Jenna Ariel Lieberman, Silvia Jimeno-González, Sander Lambo, Bola S. Hanna, Yassin Harim, Malin Jansen, Anna Neuerburg, Olga Friesen, Marc Zuckermann, Vijayanad Rajendran, Jan Gronych, Olivier Ayrault, Andrey Korshunov, David Jones, Marcel Kool, Paul A. Northcott, Peter Lichter, Felipe Cortés‐Ledesma, Stefan M. Pfister, Hai‐Kun Liu

    Udgivet 2017
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    Artigo
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  8. 8
    The Senescence-associated Secretory Phenotype Mediates Oncogene-induced Senescence in Pediatric Pilocytic Astrocytoma

    The Senescence-associated Secretory Phenotype Mediates Oncogene-induced Senescence in Pediatric Pilocytic Astrocytoma af Juliane L. Buhl, Florian Selt, Thomas Hielscher, Romain Guiho, Jonas Ecker, Felix Sahm, Johannes Ridinger, Dennis Riehl, Diren Usta, Britta Ismer, Alexander C. Sommerkamp, Juan Pedro Martı́nez-Barberá, Annika K. Wefers, Marc Remke, Daniel Picard, Stefan Pusch, Jan Gronych, Ina Oehme, Cornelis M. van Tilburg, Marcel Kool, Daniela Kühn, David Capper, Andreas von Deimling, Martin U. Schuhmann, Christel Herold‐Mende, Andrey Korshunov, Tilman Brummer, Stefan M. Pfister, David Jones, Olaf Witt, Till Milde

    Udgivet 2018
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    Artigo
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  9. 9
    Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas

    Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas af Sebastian Bender, Yujie Tang, Anders M. Lindroth, Volker Hovestadt, David Jones, Marcel Kool, Marc Zapatka, Paul A. Northcott, Dominik Sturm, Wei Wang, Bernhard Radlwimmer, Jonas W. Højfeldt, Nathalène Truffaux, David Castel, Simone Schubert, Marina Ryzhova, Huriye Seker‐Cin, Jan Gronych, Pascal D. Johann, Sebastian Stark, Jochen Meyer, Till Milde, Martin U. Schuhmann, Martin Ebinger, Camelia-Maria Monoranu, Anitha Ponnuswami, Spenser Chen, Chris Jones, Olaf Witt, V. Peter Collins, Andreas von Deimling, Nada Jabado, Stéphanie Puget, Jacques Grill, Kristian Helin, Andrey Korshunov, Peter Lichter, Michelle Monje, Christoph Plass, Yoon-Jae Cho, Stefan M. Pfister

    Udgivet 2013
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    Artigo
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  10. 10
    Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

    Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma af David Jones, Barbara Hutter, Natalie Jäger, Andrey Korshunov, Marcel Kool, Hans-Jörg Warnatz, Thomas Zichner, Sally R. Lambert, Marina Ryzhova, Dong Anh Khuong Quang, Adam M. Fontebasso, Adrian M. Stütz, Sonja Hutter, Marc Zuckermann, Dominik Sturm, Jan Gronych, Bärbel Lasitschka, Sabine Schmidt, Huriye Seker‐Cin, Hendrik Witt, Marc Sultan, Markus Ralser, Paul A. Northcott, Volker Hovestadt, Sebastian Bender, Elke Pfaff, Sebastian Stark, Damien Faury, Jeremy Schwartzentruber, Jacek Majewski, Ursula Weber, Marc Zapatka, Benjamin Raeder, Matthias Schlesner, Catherine L. Worth, Cynthia C. Bartholomae, Christof von Kalle, Charles D. Imbusch, Sylwester Radomski, Chris Lawerenz, Peter van Sluis, Jan Köster, Richard Volckmann, Rogier Versteeg, Hans Lehrach, Camelia Monoranu, Beate Winkler, Andreas Unterberg, Christel Herold‐Mende, Till Milde, Andreas E. Kulozik, Martin Ebinger, Martin U. Schuhmann, Yoon‐Jae Cho, Scott L. Pomeroy, Andreas von Deimling, Olaf Witt, Michael D. Taylor, Stephan Wolf, Matthias A. Karajannis, Charles G. Eberhart, Wolfram Scheurlen, Martin Hasselblatt, Keith L. Ligon, Mark W. Kieran, Jan O. Korbel, Marie‐Laure Yaspo, Benedikt Brors, Jörg Felsberg, Guido Reifenberger, V. Peter Collins, Nada Jabado, Roland Eils, Peter Lichter

    Udgivet 2013
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