检索结果 - James R. Downing

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  1. 1
    THE AML1‐ETO CHIMAERIC TRANSCRIPTION FACTOR IN ACUTE MYELOID LEUKAEMIA: BIOLOGY AND CLINICAL SIGNIFICANCE

    THE AML1‐ETO CHIMAERIC TRANSCRIPTION FACTOR IN ACUTE MYELOID LEUKAEMIA: BIOLOGY AND CLINICAL SIGNIFICANCE 由 James R. Downing

    出版 1999
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  2. 2
    Haploinsufficiency of AML1 results in a decrease in the number of LTR-HSCs while simultaneously inducing an increase in more mature progenitors

    Haploinsufficiency of AML1 results in a decrease in the number of LTR-HSCs while simultaneously inducing an increase in more mature progenitors 由 Weili Sun, James R. Downing

    出版 2004
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  3. 3
    Acute leukemia: A pediatric perspective

    Acute leukemia: A pediatric perspective 由 James R. Downing, Kevin Shannon

    出版 2002
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  4. 4
    The biology of pediatric acute megakaryoblastic leukemia

    The biology of pediatric acute megakaryoblastic leukemia 由 Tanja A. Grüber, James R. Downing

    出版 2015
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  5. 5
    Activators of protein kinase C enhance acetylcholine receptor desensitization in sympathetic ganglion neurons.

    Activators of protein kinase C enhance acetylcholine receptor desensitization in sympathetic ganglion neurons. 由 James R. Downing, Lorna W. Role

    出版 1987
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  6. 6
    Global Genomic Characterization of Acute Lymphoblastic Leukemia

    Global Genomic Characterization of Acute Lymphoblastic Leukemia 由 Charles G. Mullighan, James R. Downing

    出版 2008
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  7. 7
    Ligand-induced tyrosine kinase activity of the colony-stimulating factor 1 receptor in a murine macrophage cell line.

    Ligand-induced tyrosine kinase activity of the colony-stimulating factor 1 receptor in a murine macrophage cell line. 由 James R. Downing, Carl W. Rettenmier, Charles J. Sherr

    出版 1988
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  8. 8
    Ligand and protein kinase C downmodulate the colony-stimulating factor 1 receptor by independent mechanisms.

    Ligand and protein kinase C downmodulate the colony-stimulating factor 1 receptor by independent mechanisms. 由 James R. Downing, Martine F. Roussel, Charles J. Sherr

    出版 1989
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  9. 9
    Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions.

    Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein... 由 Samuel P. Meyers, James R. Downing, Scott W. Hiebert

    出版 1993
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  10. 10
    Without nerves, immunology remains incomplete –<i>in vivo veritas</i>

    Without nerves, immunology remains incomplete –<i>in vivo veritas</i> 由 Andrew J. Shepherd, James R. Downing, Jaleel A. Miyan

    出版 2005
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  11. 11
    Genomics and the Continuum of Cancer Care

    Genomics and the Continuum of Cancer Care 由 Ultan McDermott, James R. Downing, Michael R. Stratton

    出版 2011
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  12. 12
    A point mutation at tyrosine-809 in the human colony-stimulating factor 1 receptor impairs mitogenesis without abrogating tyrosine kinase activity, association with phosphatidylinositol 3-kinase, or induction of c-fos and junB genes.

    A point mutation at tyrosine-809 in the human colony-stimulating factor 1 receptor impairs mitogenesis without abrogating tyrosine kinase activity, association with phosphatidylino... 由 Martine F. Roussel, Sheila Shurtleff, James R. Downing, Charles J. Sherr

    出版 1990
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  13. 13
    Failure of <i>CDKN2A/B</i> (<i>INK4A/B–ARF</i>)-mediated tumor suppression and resistance to targeted therapy in acute lymphoblastic leukemia induced by BCR-ABL

    Failure of <i>CDKN2A/B</i> (<i>INK4A/B–ARF</i>)-mediated tumor suppression and resistance to targeted therapy in acute lymphoblastic leukemia induced by BCR-ABL 由 Charles G. Mullighan, Richard T. Williams, James R. Downing, Charles J. Sherr

    出版 2008
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  14. 14
    Mesenchymal cells regulate the response of acute lymphoblastic leukemia cells to asparaginase

    Mesenchymal cells regulate the response of acute lymphoblastic leukemia cells to asparaginase 由 Shotaro Iwamoto, Keichiro Mihara, James R. Downing, Ching‐Hon Pui, Dario Campana

    出版 2007
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  15. 15
    Simple rules underlying gene expression profiles of more than six subtypes of acute lymphoblastic leukemia (ALL) patients

    Simple rules underlying gene expression profiles of more than six subtypes of acute lymphoblastic leukemia (ALL) patients 由 Jinyan Li, Huiqing Liu, James R. Downing, Allen Eng Juh Yeoh, Limsoon Wong

    出版 2002
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  16. 16
    Role of RUNX1 in adult hematopoiesis: analysis of RUNX1-IRES-GFP knock-in mice reveals differential lineage expression

    Role of RUNX1 in adult hematopoiesis: analysis of RUNX1-IRES-GFP knock-in mice reveals differential lineage expression 由 Robert B. Lorsbach, Jennifer C. Moore, Sonny Ang, Weili Sun, Noel Lenny, James R. Downing

    出版 2003
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  17. 17
    AML1, the Target of Multiple Chromosomal Translocations in Human Leukemia, Is Essential for Normal Fetal Liver Hematopoiesis

    AML1, the Target of Multiple Chromosomal Translocations in Human Leukemia, Is Essential for Normal Fetal Liver Hematopoiesis 由 Tsukasa Okuda, Jan M. van Deursen, Scott W. Hiebert, Gerard C. Grosveld, James R. Downing

    出版 1996
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  18. 18
    FLT3 inhibition selectively kills childhood acute lymphoblastic leukemia cells with high levels of FLT3 expression

    FLT3 inhibition selectively kills childhood acute lymphoblastic leukemia cells with high levels of FLT3 expression 由 Patrick A. Brown, Mark J. Levis, Sheila Shurtleff, Dario Campana, James R. Downing, Donald Small

    出版 2004
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  19. 19
    Reference alignment of SNP microarray signals for copy number analysis of tumors

    Reference alignment of SNP microarray signals for copy number analysis of tumors 由 Stanley Pounds, Cheng Cheng, Charles G. Mullighan, Susana C. Raimondi, Sheila Shurtleff, James R. Downing

    出版 2008
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  20. 20
    Haploinsufficiency of AML1 Affects the Temporal and Spatial Generation of Hematopoietic Stem Cells in the Mouse Embryo

    Haploinsufficiency of AML1 Affects the Temporal and Spatial Generation of Hematopoietic Stem Cells in the Mouse Embryo 由 Zhongling Cai, Marella de Bruijn, Xiaoqian Ma, Bjorn Dortland, Tanya Luteijn, James R. Downing, Elaine Dzierzak

    出版 2000
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