Resultados de procura - James Doherty

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  1. 1
    Reduced Excitatory Drive onto Interneurons in the Dentate Gyrus after Status Epilepticus

    Reduced Excitatory Drive onto Interneurons in the Dentate Gyrus after Status Epilepticus por James Doherty, Raymond Dingledine

    Publicado 2001
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  2. 2
    Altered Histone Acetylation at<i>Glutamate Receptor 2</i>and<i>Brain-Derived Neurotrophic Factor</i>Genes Is an Early Event Triggered by Status Epilepticus

    Altered Histone Acetylation at<i>Glutamate Receptor 2</i>and<i>Brain-Derived Neurotrophic Factor</i>Genes Is an Early Event Triggered by Status Epilepticus por Yunfei Huang, James Doherty, Raymond Dingledine

    Publicado 2002
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  3. 3
    Stimulus-Specific Adaptation in Auditory Cortex Is an NMDA-Independent Process Distinct from the Sensory Novelty Encoded by the Mismatch Negativity

    Stimulus-Specific Adaptation in Auditory Cortex Is an NMDA-Independent Process Distinct from the Sensory Novelty Encoded by the Mismatch Negativity por Brandon J. Farley, Michael C. Quirk, James Doherty, Edward P. Christian

    Publicado 2010
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  4. 4
    Rapid force generation during unilateral isometric hamstring assessment: reliability and relationship to maximal force

    Rapid force generation during unilateral isometric hamstring assessment: reliability and relationship to maximal force por Nicholas J. Ripley, James Doherty, Matthew Cuthbert, John J. McMahon, Paul Comfort

    Publicado 2023
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  5. 5
    Endogenous and synthetic neuroactive steroids evoke sustained increases in the efficacy of GABAergic inhibition via a protein kinase C-dependent mechanism

    Endogenous and synthetic neuroactive steroids evoke sustained increases in the efficacy of GABAergic inhibition via a protein kinase C-dependent mechanism por Amit Modgil, Manasa L. Parakala, Michael A. Ackley, James Doherty, Stephen J. Moss, Paul Davies

    Publicado 2016
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  6. 6
    Open-label, proof-of-concept study of brexanolone in the treatment of severe postpartum depression

    Open-label, proof-of-concept study of brexanolone in the treatment of severe postpartum depression por Stephen Kanes, Helen Colquhoun, James Doherty, Shane Raines, Ethan Hoffmann, David R. Rubinow, Samantha Meltzer‐Brody

    Publicado 2017
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  7. 7
    An Outcome-based Approach for the Creation of Fetal Growth Standards: Do Singletons and Twins Need Separate Standards?

    An Outcome-based Approach for the Creation of Fetal Growth Standards: Do Singletons and Twins Need Separate Standards? por K.S. Joseph, James Doherty, Robert W. Platt, Robert M. Liston, S. K. Lee, Reg Sauvé, S. Liu, A C Allen, M. S. Kramer

    Publicado 2008
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  8. 8
    Brexanolone as adjunctive therapy in super‐refractory status epilepticus

    Brexanolone as adjunctive therapy in super‐refractory status epilepticus por Eric S. Rosenthal, Jan Claassen, Mark S. Wainwright, Aatif M. Husain, Henrikas Vaitkevicius, Shane Raines, Ethan Hoffmann, Helen Colquhoun, James Doherty, Stephen Kanes

    Publicado 2017
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  9. 9
    Dalzanemdor (SAGE‐718), a novel, investigational N‐methyl‐D‐aspartate receptor positive allosteric modulator: Safety, tolerability, and clinical pharmacology in randomized dose‐finding studies in healthy participants and an open‐label study in participants with Huntington's disease

    Dalzanemdor (SAGE‐718), a novel, investigational N‐methyl‐D‐aspartate receptor positive allosteric modulator: Safety, tolerability, and clinical pharmacology in randomized dose‐fin... por Aaron Koenig, Michael Lewis, Jeff Wald, Sigui Li, Mustafa Varoglu, Jing Dai, Abdul J. Sankoh, Katrina Paumier, James Doherty, Mike Quirk

    Publicado 2024
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  10. 10
    Metabotropic, but not allosteric, effects of neurosteroids on GABAergic inhibition depend on the phosphorylation of GABAA receptors

    Metabotropic, but not allosteric, effects of neurosteroids on GABAergic inhibition depend on the phosphorylation of GABAA receptors por Manasa L. Parakala, Yihui Zhang, Amit Modgil, Jayashree Chadchankar, Thuy N. Vien, Michael A. Ackley, James Doherty, Paul Davies, Stephen J. Moss

    Publicado 2019
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  11. 11
    SAGE-217, A Novel GABAA Receptor Positive Allosteric Modulator: Clinical Pharmacology and Tolerability in Randomized Phase I Dose-Finding Studies

    SAGE-217, A Novel GABAA Receptor Positive Allosteric Modulator: Clinical Pharmacology and Tolerability in Randomized Phase I Dose-Finding Studies por Ethan Hoffmann, George G. Nomikos, Inder Kaul, Shane Raines, Jeff Wald, Amy Bullock, Abdul J. Sankoh, James Doherty, Stephen Kanes, Helen Colquhoun

    Publicado 2019
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  12. 12
    Different oxysterols have opposing actions at N-methyl-d-aspartate receptors

    Different oxysterols have opposing actions at N-methyl-d-aspartate receptors por Andrew J. Linsenbardt, Amanda Taylor, Christine M. Emnett, James Doherty, Kathiresan Krishnan, Douglas F. Covey, Steven M. Paul, Charles F. Zorumski, Steven Mennerick

    Publicado 2014
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  13. 13
    Chemotherapeutic response to cisplatin-like drugs in human breast cancer cells probed by vibrational microspectroscopy

    Chemotherapeutic response to cisplatin-like drugs in human breast cancer cells probed by vibrational microspectroscopy por Ana L. M. Batista de Carvalho, Michael J. Pilling, Peter Gardner, James Doherty, Gianfelice Cinque, Katia Wehbe, Chris S. Kelley, Luís A. E. Batista de Carvalho, M. Paula M. Marques

    Publicado 2016
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  14. 14
    Positive Allosteric Modulation as a Potential Therapeutic Strategy in Anti-NMDA Receptor Encephalitis

    Positive Allosteric Modulation as a Potential Therapeutic Strategy in Anti-NMDA Receptor Encephalitis por Natasha Warikoo, Samuel J. Brunwasser, Ann Benz, Hong‐Jin Shu, Steven M. Paul, Michael Lewis, James Doherty, Michael C. Quirk, Laura Piccio, Charles F. Zorumski, Gregory S. Day, Steven Mennerick

    Publicado 2018
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  15. 15
    Effect of Zuranolone vs Placebo in Postpartum Depression

    Effect of Zuranolone vs Placebo in Postpartum Depression por Kristina M. Deligiannidis, Samantha Meltzer‐Brody, Handan Gunduz‐Bruce, James Doherty, Jeffrey M. Jonas, Sigui Li, Abdul J. Sankoh, Christopher Silber, Andrew Campbell, Brian Werneburg, Stephen Kanes, Robert Lasser

    Publicado 2021
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  16. 16
    The Major Brain Cholesterol Metabolite 24(S)-Hydroxycholesterol Is a Potent Allosteric Modulator of<i>N</i>-Methyl-d-Aspartate Receptors

    The Major Brain Cholesterol Metabolite 24(S)-Hydroxycholesterol Is a Potent Allosteric Modulator of<i>N</i>-Methyl-d-Aspartate Receptors por Steven M. Paul, James Doherty, Albert J. Robichaud, Gabriel M. Belfort, Brian Y. Chow, Rebecca Hammond, Devon C. Crawford, Andrew J. Linsenbardt, Hong‐Jin Shu, Yukitoshi Izumi, Steven Mennerick, Charles F. Zorumski

    Publicado 2013
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  17. 17
    Allosteric modulation of NMDA receptors prevents the antibody effects of patients with anti-NMDAR encephalitis

    Allosteric modulation of NMDA receptors prevents the antibody effects of patients with anti-NMDAR encephalitis por Francesco Mannara, Marija Radosevic, Jesús Planagumà, David Soto, Esther Aguilar, Anna García‐Serra, Estibaliz Maudes, Marta Pedreño, Steven M. Paul, James Doherty, Michael C. Quirk, Jing Dai, Xavier Gasull, Michael Lewis, Josep Dalmau

    Publicado 2020
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  18. 18
    <scp>AZD</scp>1080, a novel <scp>GSK</scp>3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans

    <scp>AZD</scp>1080, a novel <scp>GSK</scp>3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans por Biljana Georgievska, Johan Sandin, James Doherty, Anette Mörtberg, Jan Neelissen, Anita Andersson, Susanne Gruber, Yvonne Nilsson, P.A. Schött, Per I. Arvidsson, Sven Hellberg, Gunilla Osswald, Stefan von Berg, Johanna Fälting, Ratan V. Bhat

    Publicado 2013
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  19. 19
    Efficacy and safety of zuranolone co-initiated with an antidepressant in adults with major depressive disorder: results from the phase 3 CORAL study

    Efficacy and safety of zuranolone co-initiated with an antidepressant in adults with major depressive disorder: results from the phase 3 CORAL study por Sagar V. Parikh, Scott T. Aaronson, Sanjay J. Mathew, Gustavo Alva, Charles DeBattista, Stephen Kanes, Robert Lasser, Amy Bullock, Mona Kotecha, JungAh Jung, Fiona Forrestal, J. Jonas, Theresa Vera, Bridgette Leclair, James Doherty

    Publicado 2023
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  20. 20
    Trial of SAGE-217 in Patients with Major Depressive Disorder

    Trial of SAGE-217 in Patients with Major Depressive Disorder por Handan Gunduz-Bruce, Christopher Silber, Inder Kaul, Anthony J. Rothschild, Robert Riesenberg, Abdul J. Sankoh, Haihong Li, Robert Lasser, Charles F. Zorumski, David R. Rubinow, Steven M. Paul, Jeffrey M. Jonas, James Doherty, Stephen Kanes

    Publicado 2019
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