Resultats de la cerca - James D. Brien

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  1. 1
    West Nile Virus-Specific CD4 T Cells Exhibit Direct Antiviral Cytokine Secretion and Cytotoxicity and Are Sufficient for Antiviral Protection

    West Nile Virus-Specific CD4 T Cells Exhibit Direct Antiviral Cytokine Secretion and Cytotoxicity and Are Sufficient for Antiviral Protection per James D. Brien, Jennifer L. Uhrlaub, Janko Nikolich‐Žugich

    Publicat 2008
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  2. 2
    Protective capacity and epitope specificity of CD8<sup>+</sup> T cells responding to lethal West Nile virus infection

    Protective capacity and epitope specificity of CD8<sup>+</sup> T cells responding to lethal West Nile virus infection per James D. Brien, Jennifer L. Uhrlaub, Janko Nikolich‐Žugich

    Publicat 2007
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  3. 3
    Activation of Virus-Specific CD8+ T Cells by Lipopolysaccharide-Induced IL-12 and IL-18

    Activation of Virus-Specific CD8+ T Cells by Lipopolysaccharide-Induced IL-12 and IL-18 per Hans-Peter Raué, James D. Brien, Erika Hammarlund, Mark K. Slifka

    Publicat 2004
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  4. 4
    Identification of Protective CD8 T Cell Responses in a Mouse Model of Zika Virus Infection

    Identification of Protective CD8 T Cell Responses in a Mouse Model of Zika Virus Infection per Mariah Hassert, Madison G. Harris, James D. Brien, Amelia K. Pinto

    Publicat 2019
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  5. 5
    Key role of T cell defects in age-related vulnerability to West Nile virus

    Key role of T cell defects in age-related vulnerability to West Nile virus per James D. Brien, Jennifer L. Uhrlaub, Alec J. Hirsch, Clayton A. Wiley, Janko Nikolich‐Žugich

    Publicat 2009
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  6. 6
    The Interferon-Inducible Gene viperin Restricts West Nile Virus Pathogenesis

    The Interferon-Inducible Gene viperin Restricts West Nile Virus Pathogenesis per Kristy J. Szretter, James D. Brien, Larissa B. Thackray, Herbert W. Virgin, Peter Cresswell, Michael Diamond

    Publicat 2011
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  7. 7
    Interferon Regulatory Factor-1 (IRF-1) Shapes Both Innate and CD8+ T Cell Immune Responses against West Nile Virus Infection

    Interferon Regulatory Factor-1 (IRF-1) Shapes Both Innate and CD8+ T Cell Immune Responses against West Nile Virus Infection per James D. Brien, Stéphane Daffis, Helen M. Lazear, Hyelim Cho, Mehul S. Suthar, Michael Gale, Michael Diamond

    Publicat 2011
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  8. 8
    A Dengue Virus Serotype 1 mRNA-LNP Vaccine Elicits Protective Immune Responses

    A Dengue Virus Serotype 1 mRNA-LNP Vaccine Elicits Protective Immune Responses per Clayton J. Wollner, Michelle Richner, Mariah Hassert, Amelia K. Pinto, James D. Brien, Justin M. Richner

    Publicat 2021
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  9. 9
    Cytomegalovirus Infection Impairs Immune Responses and Accentuates T-cell Pool Changes Observed in Mice with Aging

    Cytomegalovirus Infection Impairs Immune Responses and Accentuates T-cell Pool Changes Observed in Mice with Aging per Luka Čičin‐Šain, James D. Brien, Jennifer L. Uhrlaub, Anja Drabig, Thomas F. Marandu, Janko Nikolich‐Žugich

    Publicat 2012
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  10. 10
    Dissecting the biophysical mechanisms of oleate hydratase association with membranes

    Dissecting the biophysical mechanisms of oleate hydratase association with membranes per William A. Lathram, Robert J. Neff, Ashley N. Zalla, James D. Brien, Subramanian Vivekanandan, Christopher D. Radka

    Publicat 2025
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  11. 11
    CD4+T cells mediate protection against Zika associated severe disease in a mouse model of infection

    CD4+T cells mediate protection against Zika associated severe disease in a mouse model of infection per Mariah Hassert, Kyle J. Wolf, Katherine E. Schwetye, Richard J. DiPaolo, James D. Brien, Amelia K. Pinto

    Publicat 2018
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  12. 12
    Heterotypic immunity against vaccinia virus in an HLA-B*07:02 transgenic mousepox infection model

    Heterotypic immunity against vaccinia virus in an HLA-B*07:02 transgenic mousepox infection model per Amrendra Kumar, Naveenchandra Suryadevara, Kyle J. Wolf, John T. Wilson, Richard J. Di Paolo, James D. Brien, Sebastian Joyce

    Publicat 2020
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  13. 13
    Genotype-Specific Neutralization and Protection by Antibodies against Dengue Virus Type 3

    Genotype-Specific Neutralization and Protection by Antibodies against Dengue Virus Type 3 per James D. Brien, S. Kyle Austin, Soila Sukupolvi-Petty, Katie M. O’Brien, Syd Johnson, Daved H. Fremont, Michael Diamond

    Publicat 2010
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  14. 14
    SARS-CoV-2 spike protein promotes IL-6 trans-signaling by activation of angiotensin II receptor signaling in epithelial cells

    SARS-CoV-2 spike protein promotes IL-6 trans-signaling by activation of angiotensin II receptor signaling in epithelial cells per Tapas Patra, Keith Meyer, Lizzie Geerling, T. Scott Isbell, Daniel F. Hoft, James D. Brien, Amelia K. Pinto, Ratna B. Ray, Ranjit Ray

    Publicat 2020
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  15. 15
    West Nile Virus Capsid Degradation of Claudin Proteins Disrupts Epithelial Barrier Function

    West Nile Virus Capsid Degradation of Claudin Proteins Disrupts Epithelial Barrier Function per Guruprasad R. Medigeshi, Alec J. Hirsch, James D. Brien, Jennifer L. Uhrlaub, Peter W. Mason, Clayton A. Wiley, Janko Nikolich‐Žugich, Jay A. Nelson

    Publicat 2009
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  16. 16
    Chikungunya Virus Infection Results in Higher and Persistent Viral Replication in Aged Rhesus Macaques Due to Defects in Anti-Viral Immunity

    Chikungunya Virus Infection Results in Higher and Persistent Viral Replication in Aged Rhesus Macaques Due to Defects in Anti-Viral Immunity per Ilhem Messaoudi, Jennifer Vomaske, Jennifer Totonchy, Craig N. Kreklywich, Kristen Haberthur, Laura K. Springgay, James D. Brien, Michael Diamond, Victor R. DeFilippis, Daniel N. Streblow

    Publicat 2013
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  17. 17
    A Temporal Role Of Type I Interferon Signaling in CD8+ T Cell Maturation during Acute West Nile Virus Infection

    A Temporal Role Of Type I Interferon Signaling in CD8+ T Cell Maturation during Acute West Nile Virus Infection per Amelia K. Pinto, Stéphane Daffis, James D. Brien, Maria D. Gainey, Wayne M. Yokoyama, Kathleen C. F. Sheehan, Kenneth M. Murphy, Robert D. Schreiber, Michael Diamond

    Publicat 2011
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  18. 18
    Defining New Therapeutics Using a More Immunocompetent Mouse Model of Antibody-Enhanced Dengue Virus Infection

    Defining New Therapeutics Using a More Immunocompetent Mouse Model of Antibody-Enhanced Dengue Virus Infection per Amelia K. Pinto, James D. Brien, Chia-Ying Kao Lam, Syd Johnson, Cindy Chiang, John Hiscott, Vanessa V. Sarathy, Alan D.T. Barrett, Sujan Shresta, Michael Diamond

    Publicat 2015
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  19. 19
    Functional Analysis of Antibodies against Dengue Virus Type 4 Reveals Strain-Dependent Epitope Exposure That Impacts Neutralization and Protection

    Functional Analysis of Antibodies against Dengue Virus Type 4 Reveals Strain-Dependent Epitope Exposure That Impacts Neutralization and Protection per Soila Sukupolvi-Petty, James D. Brien, S. Kyle Austin, Bimmi Shrestha, Sherri Swayne, Kristen M. Kahle, Benjamin J. Doranz, Syd Johnson, Theodore C. Pierson, Daved H. Fremont, Michael Diamond

    Publicat 2013
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  20. 20
    The Development of Therapeutic Antibodies That Neutralize Homologous and Heterologous Genotypes of Dengue Virus Type 1

    The Development of Therapeutic Antibodies That Neutralize Homologous and Heterologous Genotypes of Dengue Virus Type 1 per Bimmi Shrestha, James D. Brien, Soila Sukupolvi-Petty, S. Kyle Austin, Melissa A. Edeling, Tae-Kyung Kim, Katie M. O’Brien, Christopher A. Nelson, Syd Johnson, Daved H. Fremont, Michael Diamond

    Publicat 2010
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