检索结果 - Jaeger, Alex M

Heat shock transcription factor 1 as a therapeutic target in neurodegenerative diseases 由 Neef, Daniel W., Jaeger, Alex M., Thiele, Dennis J.

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Genetic Selection for Constitutively Trimerized Human HSF1 Mutants Identifies a Role for Coiled-Coil Motifs in DNA Binding 由 Neef, Daniel W., Jaeger, Alex M., Thiele, Dennis J.

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Structures of HSF2 Reveal Mechanisms for Differential Regulation of Human Heat Shock Factors 由 Jaeger, Alex M., Pemble, Charles W., Sistonen, Lea, Thiele, Dennis J.

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Agonist-directed Interactions with Specific β-Arrestins Determine μ-Opioid Receptor Trafficking, Ubiquitination, and Dephosphorylation 由 Groer, Chad E., Schmid, Cullen L., Jaeger, Alex M., Bohn, Laura M.

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Genomic Heat Shock Element Sequences Drive Cooperative Human Heat Shock Factor 1 DNA Binding and Selectivity 由 Jaeger, Alex M., Makley, Leah N., Gestwicki, Jason E., Thiele, Dennis J.

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Rebalancing protein homeostasis enhances tumor antigen presentation 由 Jaeger, Alex M., Stopfer, Lauren, Lee, Sunmin, Gaglia, Giorgio, Sandel, Demi, Santagata, Sandro, Lin, Nancy U., Trepel, Jane B., White, Forest, Jacks, Tyler, Lindquist, Susan, Whitesell, Luke

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Abnormal degradation of the neuronal stress-protective transcription factor HSF1 in Huntington's disease 由 Gomez-Pastor, Rocio, Burchfiel, Eileen T., Neef, Daniel W., Jaeger, Alex M., Cabiscol, Elisa, McKinstry, Spencer U., Doss, Argenia, Aballay, Alejandro, Lo, Donald C., Akimov, Sergey S., Ross, Christopher A., Eroglu, Cagla, Thiele, Dennis J.

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Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes 由 Genshaft, Alex S, Ziegler, Carly G. K., Tzouanas, Constantine N., Mead, Benjamin E., Jaeger, Alex M., Navia, Andrew W., King, Ryan P., Mana, Miyeko D., Huang, Siyi, Mitsialis, Vanessa, Snapper, Scott B., Yilmaz, Ömer H., Jacks, Tyler, Van Humbeck, Jeffrey F., Shalek, Alex K.

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Publisher Correction: Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes 由 Genshaft, Alex S., Ziegler, Carly G. K., Tzouanas, Constantine N., Mead, Benjamin E., Jaeger, Alex M., Navia, Andrew W., King, Ryan P., Mana, Miyeko D., Huang, Siyi, Mitsialis, Vanessa, Snapper, Scott B., Yilmaz, Ömer H., Jacks, Tyler, Van Humbeck, Jeffrey F., Shalek, Alex K.

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Low neoantigen expression and poor T-cell priming underlie early immune escape in colorectal cancer 由 Westcott, Peter M K, Sacks, Nathan J, Schenkel, Jason M, Ely, Zackery A, Smith, Olivia, Hauck, Haley, Jaeger, Alex M, Zhang, Daniel, Backlund, Coralie M, Beytagh, Mary C, Patten, JJ, Elbashir, Ryan, Eng, George, Irvine, Darrell J, Yilmaz, Omer H, Jacks, Tyler

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Inhibition of translation initiation factor eIF4a inactivates heat shock factor 1 (HSF1) and exerts anti-leukemia activity in AML 由 Nishida, Yuki, Zhao, Ran, Heese, Lauren E., Akiyama, Hiroki, Patel, Shreya, Jaeger, Alex M., Jacamo, Rodrigo O., Kojima, Kensuke, Ma, Man Chun John, Ruvolo, Vivian R., Chachad, Dhruv, Devine, William, Lindquist, Susan, Davis, R. Eric, Porco, John A., Whitesell, Luke, Andreeff, Michael, Ishizawa, Jo

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Identification of an Allosteric Small Molecule Inhibitor Selective for Inducible Form of Heat Shock Protein 70 由 Howe, Matthew K., Bodoor, Khaldon, Carlson, David A., Hughes, Philip F., Alwarawrah, Yazan, Loiselle, David R., Jaeger, Alex M., Darr, David B., Jordan, Jamie L., Hunter, Lucas M., Molzberger, Eileen T., Gobillot, Theodore A., Thiele, Dennis J., Brodsky, Jeffrey L., Spector, Neil L., Haystead, Timothy A. J.

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The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer 由 Freed-Pastor, William A, Lambert, Laurens J, Ely, Zackery A, Pattada, Nimisha B, Bhutkar, Arjun, Eng, George, Mercer, Kim L, Garcia, Ana P, Lin, Lin, Rideout, William M, Hwang, William L, Schenkel, Jason M, Jaeger, Alex M, Bronson, Roderick T, Westcott, Peter MK, Hether, Tyler D, Divakar, Prajan, Reeves, Jason W, Deshpande, Vikram, Delorey, Toni, Phillips, Devan, Yilmaz, Omer H, Regev, Aviv, Jacks, Tyler

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Antigen Dominance Hierarchies Shape TCF1+ Progenitor CD8 T Cell Phenotypes in Tumors 由 Burger, Megan L., Cruz, Amanda M., Crossland, Grace E., Gaglia, Giorgio, Ritch, Cecily C., Blatt, Sarah E., Bhutkar, Arjun, Canner, David, Kienka, Tamina, Tavana, Sara Z., Barandiaran, Alexia L., Garmilla, Andrea, Schenkel, Jason M., Hillman, Michelle, de los Rios Kobara, Izumi, Li, Amy, Jaeger, Alex M., Hwang, William L., Westcott, Peter M. K., Manos, Michael P., Holovatska, Marta M., Hodi, F. Stephen, Regev, Aviv, Santagata, Sandro, Jacks, Tyler

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Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer 由 Raghavan, Srivatsan, Winter, Peter S., Navia, Andrew W., Williams, Hannah L., DenAdel, Alan, Lowder, Kristen E., Galvez-Reyes, Jennyfer, Kalekar, Radha L., Mulugeta, Nolawit, Kapner, Kevin S., Raghavan, Manisha S., Borah, Ashir A., Liu, Nuo, Väyrynen, Sara A., Costa, Andressa Dias, Ng, Raymond W.S., Wang, Junning, Hill, Emma K., Ragon, Dorisanne Y., Brais, Lauren K., Jaeger, Alex M., Spurr, Liam F., Li, Yvonne Y., Cherniack, Andrew D., Booker, Matthew A., Cohen, Elizabeth F., Tolstorukov, Michael Y., Wakiro, Isaac, Rotem, Asaf, Johnson, Bruce E., McFarland, James M., Sicinska, Ewa T., Jacks, Tyler E., Sullivan, Ryan J., Shapiro, Geoffrey I., Clancy, Thomas E., Perez, Kimberly, Rubinson, Douglas A., Ng, Kimmie, Cleary, James M., Crawford, Lorin, Manalis, Scott R., Nowak, Jonathan A., Wolpin, Brian M., Hahn, William C., Aguirre, Andrew J., Shalek, Alex K.

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