Výsledky vyhledávání - Jaeger, Alex M

Heat shock transcription factor 1 as a therapeutic target in neurodegenerative diseases Autor Neef, Daniel W., Jaeger, Alex M., Thiele, Dennis J.

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Genetic Selection for Constitutively Trimerized Human HSF1 Mutants Identifies a Role for Coiled-Coil Motifs in DNA Binding Autor Neef, Daniel W., Jaeger, Alex M., Thiele, Dennis J.

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Structures of HSF2 Reveal Mechanisms for Differential Regulation of Human Heat Shock Factors Autor Jaeger, Alex M., Pemble, Charles W., Sistonen, Lea, Thiele, Dennis J.

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Agonist-directed Interactions with Specific β-Arrestins Determine μ-Opioid Receptor Trafficking, Ubiquitination, and Dephosphorylation Autor Groer, Chad E., Schmid, Cullen L., Jaeger, Alex M., Bohn, Laura M.

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Genomic Heat Shock Element Sequences Drive Cooperative Human Heat Shock Factor 1 DNA Binding and Selectivity Autor Jaeger, Alex M., Makley, Leah N., Gestwicki, Jason E., Thiele, Dennis J.

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Rebalancing protein homeostasis enhances tumor antigen presentation Autor Jaeger, Alex M., Stopfer, Lauren, Lee, Sunmin, Gaglia, Giorgio, Sandel, Demi, Santagata, Sandro, Lin, Nancy U., Trepel, Jane B., White, Forest, Jacks, Tyler, Lindquist, Susan, Whitesell, Luke

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Abnormal degradation of the neuronal stress-protective transcription factor HSF1 in Huntington's disease Autor Gomez-Pastor, Rocio, Burchfiel, Eileen T., Neef, Daniel W., Jaeger, Alex M., Cabiscol, Elisa, McKinstry, Spencer U., Doss, Argenia, Aballay, Alejandro, Lo, Donald C., Akimov, Sergey S., Ross, Christopher A., Eroglu, Cagla, Thiele, Dennis J.

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Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes Autor Genshaft, Alex S, Ziegler, Carly G. K., Tzouanas, Constantine N., Mead, Benjamin E., Jaeger, Alex M., Navia, Andrew W., King, Ryan P., Mana, Miyeko D., Huang, Siyi, Mitsialis, Vanessa, Snapper, Scott B., Yilmaz, Ömer H., Jacks, Tyler, Van Humbeck, Jeffrey F., Shalek, Alex K.

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Publisher Correction: Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes Autor Genshaft, Alex S., Ziegler, Carly G. K., Tzouanas, Constantine N., Mead, Benjamin E., Jaeger, Alex M., Navia, Andrew W., King, Ryan P., Mana, Miyeko D., Huang, Siyi, Mitsialis, Vanessa, Snapper, Scott B., Yilmaz, Ömer H., Jacks, Tyler, Van Humbeck, Jeffrey F., Shalek, Alex K.

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Low neoantigen expression and poor T-cell priming underlie early immune escape in colorectal cancer Autor Westcott, Peter M K, Sacks, Nathan J, Schenkel, Jason M, Ely, Zackery A, Smith, Olivia, Hauck, Haley, Jaeger, Alex M, Zhang, Daniel, Backlund, Coralie M, Beytagh, Mary C, Patten, JJ, Elbashir, Ryan, Eng, George, Irvine, Darrell J, Yilmaz, Omer H, Jacks, Tyler

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Inhibition of translation initiation factor eIF4a inactivates heat shock factor 1 (HSF1) and exerts anti-leukemia activity in AML Autor Nishida, Yuki, Zhao, Ran, Heese, Lauren E., Akiyama, Hiroki, Patel, Shreya, Jaeger, Alex M., Jacamo, Rodrigo O., Kojima, Kensuke, Ma, Man Chun John, Ruvolo, Vivian R., Chachad, Dhruv, Devine, William, Lindquist, Susan, Davis, R. Eric, Porco, John A., Whitesell, Luke, Andreeff, Michael, Ishizawa, Jo

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Identification of an Allosteric Small Molecule Inhibitor Selective for Inducible Form of Heat Shock Protein 70 Autor Howe, Matthew K., Bodoor, Khaldon, Carlson, David A., Hughes, Philip F., Alwarawrah, Yazan, Loiselle, David R., Jaeger, Alex M., Darr, David B., Jordan, Jamie L., Hunter, Lucas M., Molzberger, Eileen T., Gobillot, Theodore A., Thiele, Dennis J., Brodsky, Jeffrey L., Spector, Neil L., Haystead, Timothy A. J.

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The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer Autor Freed-Pastor, William A, Lambert, Laurens J, Ely, Zackery A, Pattada, Nimisha B, Bhutkar, Arjun, Eng, George, Mercer, Kim L, Garcia, Ana P, Lin, Lin, Rideout, William M, Hwang, William L, Schenkel, Jason M, Jaeger, Alex M, Bronson, Roderick T, Westcott, Peter MK, Hether, Tyler D, Divakar, Prajan, Reeves, Jason W, Deshpande, Vikram, Delorey, Toni, Phillips, Devan, Yilmaz, Omer H, Regev, Aviv, Jacks, Tyler

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Antigen Dominance Hierarchies Shape TCF1+ Progenitor CD8 T Cell Phenotypes in Tumors Autor Burger, Megan L., Cruz, Amanda M., Crossland, Grace E., Gaglia, Giorgio, Ritch, Cecily C., Blatt, Sarah E., Bhutkar, Arjun, Canner, David, Kienka, Tamina, Tavana, Sara Z., Barandiaran, Alexia L., Garmilla, Andrea, Schenkel, Jason M., Hillman, Michelle, de los Rios Kobara, Izumi, Li, Amy, Jaeger, Alex M., Hwang, William L., Westcott, Peter M. K., Manos, Michael P., Holovatska, Marta M., Hodi, F. Stephen, Regev, Aviv, Santagata, Sandro, Jacks, Tyler

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Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer Autor Raghavan, Srivatsan, Winter, Peter S., Navia, Andrew W., Williams, Hannah L., DenAdel, Alan, Lowder, Kristen E., Galvez-Reyes, Jennyfer, Kalekar, Radha L., Mulugeta, Nolawit, Kapner, Kevin S., Raghavan, Manisha S., Borah, Ashir A., Liu, Nuo, Väyrynen, Sara A., Costa, Andressa Dias, Ng, Raymond W.S., Wang, Junning, Hill, Emma K., Ragon, Dorisanne Y., Brais, Lauren K., Jaeger, Alex M., Spurr, Liam F., Li, Yvonne Y., Cherniack, Andrew D., Booker, Matthew A., Cohen, Elizabeth F., Tolstorukov, Michael Y., Wakiro, Isaac, Rotem, Asaf, Johnson, Bruce E., McFarland, James M., Sicinska, Ewa T., Jacks, Tyler E., Sullivan, Ryan J., Shapiro, Geoffrey I., Clancy, Thomas E., Perez, Kimberly, Rubinson, Douglas A., Ng, Kimmie, Cleary, James M., Crawford, Lorin, Manalis, Scott R., Nowak, Jonathan A., Wolpin, Brian M., Hahn, William C., Aguirre, Andrew J., Shalek, Alex K.

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