Search Results - Jacqueline A. Lees

Jacqueline Lees

Jacqueline A. Lees is a British biochemist.

Lees is the Virginia and D.K. Ludwig Professor for Cancer Research and associate director of the Koch Institute for Integrative Cancer Research at Massachusetts Institute of Technology. She received her BSc degree from the University of York in 1986, and her PhD from the University of London in 1990, both in biochemistry. She was a postdoc in the laboratory of Ed Harlow, first at Cold Spring Harbor and then at Massachusetts General Hospital, before joining the faculty at MIT in 1994. Provided by Wikipedia
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  1. 1
    Life and death decisions by the E2F transcription factors

    Life and death decisions by the E2F transcription factors by Phillip J. Iaquinta, Jacqueline A. Lees

    Published 2007
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  2. 2
    E2f4 and E2f5 are essential for the development of the male reproductive system

    E2f4 and E2f5 are essential for the development of the male reproductive system by Paul S. Danielian, Rex A. Hess, Jacqueline A. Lees

    Published 2016
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  3. 3
    Identification of two transactlvation domains in the mouse oestrogen receptor

    Identification of two transactlvation domains in the mouse oestrogen receptor by Jacqueline A. Lees, Stephen E. Fawell, Malcolm G. Parker

    Published 1989
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  4. 4
    E2F-4 Switches from p130 to p107 and pRB in Response to Cell Cycle Reentry

    E2F-4 Switches from p130 to p107 and pRB in Response to Cell Cycle Reentry by Kenneth H. Moberg, Michelle A. Starz, Jacqueline A. Lees

    Published 1996
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  5. 5
    Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors.

    Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors. by Paul S. Danielian, R White, Jacqueline A. Lees, Malcolm G. Parker

    Published 1992
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  6. 6
    Differential regulation of E2F transactivation by cyclin/cdk2 complexes.

    Differential regulation of E2F transactivation by cyclin/cdk2 complexes. by Brian David Dynlacht, Osvaldo Flores, Jacqueline A. Lees, Ed Harlow

    Published 1994
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  7. 7
    E2F3 contributes both to the inappropriate proliferation and to the apoptosis arising in <i>Rb</i> mutant embryos

    E2F3 contributes both to the inappropriate proliferation and to the apoptosis arising in <i>Rb</i> mutant embryos by Ulrike Ziebold, Tammi L. Reza, Alicia Caron, Jacqueline A. Lees

    Published 2001
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  8. 8
    E2F3 Loss Has Opposing Effects on Different pRB-Deficient Tumors, Resulting in Suppression of Pituitary Tumors but Metastasis of Medullary Thyroid Carcinomas

    E2F3 Loss Has Opposing Effects on Different pRB-Deficient Tumors, Resulting in Suppression of Pituitary Tumors but Metastasis of Medullary Thyroid Carcinomas by Ulrike Ziebold, Eunice Y. Lee, Roderick T. Bronson, Jacqueline A. Lees

    Published 2003
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  9. 9
    Repression of the <i>Arf</i> tumor suppressor by E2F3 is required for normal cell cycle kinetics

    Repression of the <i>Arf</i> tumor suppressor by E2F3 is required for normal cell cycle kinetics by Aaron Aslanian, Phillip J. Iaquinta, Raluca Verona, Jacqueline A. Lees

    Published 2004
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  10. 10
    A 22-amino-acid peptide restores DNA-binding activity to dimerization-defective mutants of the estrogen receptor.

    A 22-amino-acid peptide restores DNA-binding activity to dimerization-defective mutants of the estrogen receptor. by Jacqueline A. Lees, Stephen E. Fawell, R White, Malcolm G. Parker

    Published 1990
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  11. 11
    E2F4 Is Exported from the Nucleus in a CRM1-Dependent Manner

    E2F4 Is Exported from the Nucleus in a CRM1-Dependent Manner by Stefan Gaubatz, Jacqueline A. Lees, Geoffrey J. Lindeman, David M. Livingston

    Published 2001
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  12. 12
    p53-Deficient Cells Rely on ATM- and ATR-Mediated Checkpoint Signaling through the p38MAPK/MK2 Pathway for Survival after DNA Damage

    p53-Deficient Cells Rely on ATM- and ATR-Mediated Checkpoint Signaling through the p38MAPK/MK2 Pathway for Survival after DNA Damage by Hans Christian Reinhardt, Aaron Aslanian, Jacqueline A. Lees, Michael B. Yaffe

    Published 2007
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  13. 13
    BMI1 induces an invasive signature in melanoma that promotes metastasis and chemoresistance

    BMI1 induces an invasive signature in melanoma that promotes metastasis and chemoresistance by Roberta Ferretti, Arjun Bhutkar, Molly C. McNamara, Jacqueline A. Lees

    Published 2015
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  14. 14
    Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion

    Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion by Jennifer Shepard Dovey, Sima J. Zacharek, Carla F. Kim, Jacqueline A. Lees

    Published 2008
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  15. 15
    The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex

    The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex by Jeffrey M. Trimarchi, Brian D. Fairchild, Jessica H. Wen, Jacqueline A. Lees

    Published 2001
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  16. 16
    Structural Organization and Expression of the Mouse Estrogen Receptor

    Structural Organization and Expression of the Mouse Estrogen Receptor by R White, Jacqueline A. Lees, M. Needham, Jonathan Ham, Malcolm G. Parker

    Published 1987
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  17. 17
    In Vivo Association of E2F and DP Family Proteins

    In Vivo Association of E2F and DP Family Proteins by Chin‐Lee Wu, Lawrence Zukerberg, Chidi Ngwu, Ed Harlow, Jacqueline A. Lees

    Published 1995
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  18. 18
    Many ribosomal protein mutations are associated with growth impairment and tumor predisposition in zebrafish

    Many ribosomal protein mutations are associated with growth impairment and tumor predisposition in zebrafish by Kevin Lai, Adam Amsterdam, Sarah Farrington, Roderick T. Bronson, Nancy Hopkins, Jacqueline A. Lees

    Published 2008
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  19. 19
    Specific Regulation of E2F Family Members by Cyclin-Dependent Kinases

    Specific Regulation of E2F Family Members by Cyclin-Dependent Kinases by Brian David Dynlacht, Kenneth H. Moberg, Jacqueline A. Lees, Ed Harlow, Liang Zhu

    Published 1997
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  20. 20
    Loss of p53 synthesis in zebrafish tumors with ribosomal protein gene mutations

    Loss of p53 synthesis in zebrafish tumors with ribosomal protein gene mutations by Alyson W. MacInnes, Adam Amsterdam, Charles A. Whittaker, Nancy Hopkins, Jacqueline A. Lees

    Published 2008
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