Rezultati - Jacob D. Jaffe

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  1. 1
    The Influence of Higher-Order Epistasis on Biological Fitness Landscape Topography

    The Influence of Higher-Order Epistasis on Biological Fitness Landscape Topography od Daniel Weinreich, Yinghong Lan, Jacob D. Jaffe, Robert B. Heckendorn

    Izdano 2018
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  2. 2
    Quantitative Assessment of Chromatin Immunoprecipitation Grade Antibodies Directed against Histone Modifications Reveals Patterns of Co-occurring Marks on Histone Protein Molecules

    Quantitative Assessment of Chromatin Immunoprecipitation Grade Antibodies Directed against Histone Modifications Reveals Patterns of Co-occurring Marks on Histone Protein Molecules od Sally E. Peach, Emily L. Rudomin, Namrata D. Udeshi, Steven A. Carr, Jacob D. Jaffe

    Izdano 2012
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  3. 3
    Naturally occurring aminoacyl-tRNA synthetases editing-domain mutations that cause mistranslation in <i>Mycoplasma</i> parasites

    Naturally occurring aminoacyl-tRNA synthetases editing-domain mutations that cause mistranslation in <i>Mycoplasma</i> parasites od Li Li, Michal T. Boniecki, Jacob D. Jaffe, Brian S. Imai, Peter M. Yau, Zaida Luthey‐Schulten, Susan A. Martinis

    Izdano 2011
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  4. 4
    H2A.Z landscapes and dual modifications in pluripotent and multipotent stem cells underlie complex genome regulatory functions

    H2A.Z landscapes and dual modifications in pluripotent and multipotent stem cells underlie complex genome regulatory functions od Manching Ku, Jacob D. Jaffe, Richard P. Koche, Esther Rheinbay, Mitsuhiro Endoh, Haruhiko Koseki, Steven A. Carr, B Bernstein

    Izdano 2012
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  5. 5
    mSin1 Is Necessary for Akt/PKB Phosphorylation, and Its Isoforms Define Three Distinct mTORC2s

    mSin1 Is Necessary for Akt/PKB Phosphorylation, and Its Isoforms Define Three Distinct mTORC2s od María A. Frías, Carson C. Thoreen, Jacob D. Jaffe, Wayne A. Schroder, Tom Sculley, Steven A. Carr, David M. Sabatini

    Izdano 2006
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  6. 6
    Methods for Quantification of in vivo Changes in Protein Ubiquitination following Proteasome and Deubiquitinase Inhibition

    Methods for Quantification of in vivo Changes in Protein Ubiquitination following Proteasome and Deubiquitinase Inhibition od Namrata D. Udeshi, D.R. Mani, Thomas Eisenhaure, Philipp Mertins, Jacob D. Jaffe, Karl R. Clauser, Nir Hacohen, Steven A. Carr

    Izdano 2012
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  7. 7
    Study of mitotic chromatin supports a model of bookmarking by histone modifications and reveals nucleosome deposition patterns

    Study of mitotic chromatin supports a model of bookmarking by histone modifications and reveals nucleosome deposition patterns od Elisheva Javasky, Inbal Shamir, Shashi Gandhi, Shawn B. Egri, Oded Sandler, Scott B. Rothbart, N. Kaplan, Jacob D. Jaffe, Alon Goren, Itamar Simon

    Izdano 2018
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  8. 8
    H2A.Z.1 Monoubiquitylation Antagonizes BRD2 to Maintain Poised Chromatin in ESCs

    H2A.Z.1 Monoubiquitylation Antagonizes BRD2 to Maintain Poised Chromatin in ESCs od Lauren E. Surface, Paul Fields, Vidya Subramanian, Russell Behmer, Namrata D. Udeshi, Sally E. Peach, Steven A. Carr, Jacob D. Jaffe, Laurie A. Boyer

    Izdano 2016
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  9. 9
    Developmental Control of Polycomb Subunit Composition by GATA Factors Mediates a Switch to Non-Canonical Functions

    Developmental Control of Polycomb Subunit Composition by GATA Factors Mediates a Switch to Non-Canonical Functions od Jian Xu, Zhen Shao, Dan Li, Huafeng Xie, Woojin Kim, Jialiang Huang, Jordan E. Taylor, Luca Pinello, Kimberly Glass, Jacob D. Jaffe, Guo‐Cheng Yuan, Stuart H. Orkin

    Izdano 2015
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  10. 10
    Building the Connectivity Map of epigenetics: Chromatin profiling by quantitative targeted mass spectrometry

    Building the Connectivity Map of epigenetics: Chromatin profiling by quantitative targeted mass spectrometry od Amanda L. Creech, Jordan E. Taylor, Verena Maier, Xiaoyun Wu, Caitlin M. Feeney, Namrata D. Udeshi, Sally E. Peach, Jesse S. Boehm, Jeannie T. Lee, Steven A. Carr, Jacob D. Jaffe

    Izdano 2014
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  11. 11
    STK33 kinase inhibitor BRD-8899 has no effect on KRAS-dependent cancer cell viability

    STK33 kinase inhibitor BRD-8899 has no effect on KRAS-dependent cancer cell viability od Tuoping Luo, Kristina Masson, Jacob D. Jaffe, Whitney Silkworth, Nathan T. Ross, Christina Scherer, Claudia Scholl, Stefan Fröhling, Steven A. Carr, Andrew M. Stern, Stuart L. Schreiber, Todd R. Golub

    Izdano 2012
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  12. 12
    Phosphorylation of RAB7 by TBK1/IKKϵ Regulates Innate Immune Signaling in Triple-Negative Breast Cancer

    Phosphorylation of RAB7 by TBK1/IKKϵ Regulates Innate Immune Signaling in Triple-Negative Breast Cancer od Jessica Ritter, Zehua Zhu, Tran C. Thai, Navin R. Mahadevan, Philipp Mertins, Erik H. Knelson, Brandon Piel, Saemi Han, Jacob D. Jaffe, Steven A. Carr, David A. Barbie, Thanh U. Barbie

    Izdano 2019
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  13. 13
    Causal interactions from proteomic profiles: Molecular data meet pathway knowledge

    Causal interactions from proteomic profiles: Molecular data meet pathway knowledge od Özgün Babur, Augustin Luna, Anil Korkut, Funda Durupınar, Metin Can Siper, Uḡur Doḡrusöz, Alvaro Sebastian Vaca Jacome, Ryan Peckner, Karen E. Christianson, Jacob D. Jaffe, Paul T. Spellman, Joseph E. Aslan, Chris Sander, Emek Demir

    Izdano 2021
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  14. 14
    Down-syndrome-induced senescence disrupts the nuclear architecture of neural progenitors

    Down-syndrome-induced senescence disrupts the nuclear architecture of neural progenitors od Hiruy S. Meharena, Asaf Marco, Vishnu Dileep, Elana R. Lockshin, Grace Y. Akatsu, James Mullahoo, L. Ashley Watson, Tak Ko, Lindsey N. Guerin, Fatema Abdurrob, Shruthi Rengarajan, Malvina Papanastasiou, Jacob D. Jaffe, Li‐Huei Tsai

    Izdano 2022
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  15. 15
    Functional Proteomic Analysis of Repressive Histone Methyltransferase Complexes Reveals ZNF518B as a G9A Regulator*

    Functional Proteomic Analysis of Repressive Histone Methyltransferase Complexes Reveals ZNF518B as a G9A Regulator* od Verena Maier, Caitlin M. Feeney, Jordan E. Taylor, Amanda L. Creech, Jana Qiao, Attila Szántó, Partha Pratim Das, Nicholas Chevrier, Catherine Cifuentes‐Rojas, Stuart H. Orkin, Steven A. Carr, Jacob D. Jaffe, Philipp Mertins, Jeannie T. Lee

    Izdano 2015
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  16. 16
    Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers

    Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers od Joseph Rosenbluh, Johnathan Mercer, Yashaswi Shrestha, Rachel A. Oliver, Pablo Tamayo, John G. Doench, Itay Tirosh, Federica Piccioni, Ella Hartenian, Heiko Horn, Lọla Fagbami, David E. Root, Jacob D. Jaffe, Kasper Lage, Jesse S. Boehm, William C. Hahn

    Izdano 2016
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  17. 17
    A Curated Resource for Phosphosite-specific Signature Analysis

    A Curated Resource for Phosphosite-specific Signature Analysis od Karsten Krug, Philipp Mertins, Bin Zhang, Peter Hornbeck, Rajesh Raju, Rushdy Ahmad, Matthew J. Szucs, Filip Mundt, Dominique Forestier, Judit Jané‐Valbuena, Hasmik Keshishian, Michael A. Gillette, Pablo Tamayo, Jill P. Mesirov, Jacob D. Jaffe, StevenA. Carr, D.R. Mani

    Izdano 2018
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  18. 18
    The nucleosome acidic patch and H2A ubiquitination underlie mSWI/SNF recruitment in synovial sarcoma

    The nucleosome acidic patch and H2A ubiquitination underlie mSWI/SNF recruitment in synovial sarcoma od Matthew J. McBride, Nazar Mashtalir, Evan B. Winter, Hai T. Dao, Martin Filipovski, Andrew R. D’Avino, Hyuk‐Soo Seo, Neil T. Umbreit, Roodolph St. Pierre, Alfredo M. Valencia, Kristin Qian, Hayley Zullow, Jacob D. Jaffe, Sirano Dhe‐Paganon, Tom W. Muir, Cigall Kadoch

    Izdano 2020
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  19. 19
    HIF activation causes synthetic lethality between the <i>VHL</i> tumor suppressor and the <i>EZH1</i> histone methyltransferase

    HIF activation causes synthetic lethality between the <i>VHL</i> tumor suppressor and the <i>EZH1</i> histone methyltransferase od Abhishek A. Chakraborty, Eijiro Nakamura, Jun Qi, Amanda L. Creech, Jacob D. Jaffe, Joshiawa Paulk, Jesse Novak, Kshithija Nagulapalli, Samuel K. McBrayer, Glenn S. Cowley, Javier Pineda, Jiaxi Song, Yaoyu E. Wang, Steven A. Carr, David E. Root, Sabina Signoretti, James E. Bradner, William G. Kaelin

    Izdano 2017
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  20. 20
    Plasticity in patterns of histone modifications and chromosomal proteins in <i>Drosophila</i> heterochromatin

    Plasticity in patterns of histone modifications and chromosomal proteins in <i>Drosophila</i> heterochromatin od Nicole C. Riddle, Aki Minoda, Peter V. Kharchenko, Artyom A. Alekseyenko, Yuri B. Schwartz, Michael Tolstorukov, Andrey A. Gorchakov, Jacob D. Jaffe, Cameron Kennedy, Daniela Linder-Basso, Sally E. Peach, Gregory Shanower, Haiyan Zheng, Mitzi I. Kuroda, Vincenzo Pirrotta, Peter J. Park, Sarah C. R. Elgin, Gary H. Karpen

    Izdano 2010
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