Resultados de procura - Jacob D. Jaffe

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  1. 1
    The Influence of Higher-Order Epistasis on Biological Fitness Landscape Topography

    The Influence of Higher-Order Epistasis on Biological Fitness Landscape Topography por Daniel Weinreich, Yinghong Lan, Jacob D. Jaffe, Robert B. Heckendorn

    Publicado 2018
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  2. 2
    Quantitative Assessment of Chromatin Immunoprecipitation Grade Antibodies Directed against Histone Modifications Reveals Patterns of Co-occurring Marks on Histone Protein Molecules

    Quantitative Assessment of Chromatin Immunoprecipitation Grade Antibodies Directed against Histone Modifications Reveals Patterns of Co-occurring Marks on Histone Protein Molecules por Sally E. Peach, Emily L. Rudomin, Namrata D. Udeshi, Steven A. Carr, Jacob D. Jaffe

    Publicado 2012
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  3. 3
    Naturally occurring aminoacyl-tRNA synthetases editing-domain mutations that cause mistranslation in <i>Mycoplasma</i> parasites

    Naturally occurring aminoacyl-tRNA synthetases editing-domain mutations that cause mistranslation in <i>Mycoplasma</i> parasites por Li Li, Michal T. Boniecki, Jacob D. Jaffe, Brian S. Imai, Peter M. Yau, Zaida Luthey‐Schulten, Susan A. Martinis

    Publicado 2011
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  4. 4
    H2A.Z landscapes and dual modifications in pluripotent and multipotent stem cells underlie complex genome regulatory functions

    H2A.Z landscapes and dual modifications in pluripotent and multipotent stem cells underlie complex genome regulatory functions por Manching Ku, Jacob D. Jaffe, Richard P. Koche, Esther Rheinbay, Mitsuhiro Endoh, Haruhiko Koseki, Steven A. Carr, B Bernstein

    Publicado 2012
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  5. 5
    mSin1 Is Necessary for Akt/PKB Phosphorylation, and Its Isoforms Define Three Distinct mTORC2s

    mSin1 Is Necessary for Akt/PKB Phosphorylation, and Its Isoforms Define Three Distinct mTORC2s por María A. Frías, Carson C. Thoreen, Jacob D. Jaffe, Wayne A. Schroder, Tom Sculley, Steven A. Carr, David M. Sabatini

    Publicado 2006
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  6. 6
    Methods for Quantification of in vivo Changes in Protein Ubiquitination following Proteasome and Deubiquitinase Inhibition

    Methods for Quantification of in vivo Changes in Protein Ubiquitination following Proteasome and Deubiquitinase Inhibition por Namrata D. Udeshi, D.R. Mani, Thomas Eisenhaure, Philipp Mertins, Jacob D. Jaffe, Karl R. Clauser, Nir Hacohen, Steven A. Carr

    Publicado 2012
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  7. 7
    Study of mitotic chromatin supports a model of bookmarking by histone modifications and reveals nucleosome deposition patterns

    Study of mitotic chromatin supports a model of bookmarking by histone modifications and reveals nucleosome deposition patterns por Elisheva Javasky, Inbal Shamir, Shashi Gandhi, Shawn B. Egri, Oded Sandler, Scott B. Rothbart, N. Kaplan, Jacob D. Jaffe, Alon Goren, Itamar Simon

    Publicado 2018
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  8. 8
    H2A.Z.1 Monoubiquitylation Antagonizes BRD2 to Maintain Poised Chromatin in ESCs

    H2A.Z.1 Monoubiquitylation Antagonizes BRD2 to Maintain Poised Chromatin in ESCs por Lauren E. Surface, Paul Fields, Vidya Subramanian, Russell Behmer, Namrata D. Udeshi, Sally E. Peach, Steven A. Carr, Jacob D. Jaffe, Laurie A. Boyer

    Publicado 2016
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  9. 9
    Developmental Control of Polycomb Subunit Composition by GATA Factors Mediates a Switch to Non-Canonical Functions

    Developmental Control of Polycomb Subunit Composition by GATA Factors Mediates a Switch to Non-Canonical Functions por Jian Xu, Zhen Shao, Dan Li, Huafeng Xie, Woojin Kim, Jialiang Huang, Jordan E. Taylor, Luca Pinello, Kimberly Glass, Jacob D. Jaffe, Guo‐Cheng Yuan, Stuart H. Orkin

    Publicado 2015
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  10. 10
    Building the Connectivity Map of epigenetics: Chromatin profiling by quantitative targeted mass spectrometry

    Building the Connectivity Map of epigenetics: Chromatin profiling by quantitative targeted mass spectrometry por Amanda L. Creech, Jordan E. Taylor, Verena Maier, Xiaoyun Wu, Caitlin M. Feeney, Namrata D. Udeshi, Sally E. Peach, Jesse S. Boehm, Jeannie T. Lee, Steven A. Carr, Jacob D. Jaffe

    Publicado 2014
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  11. 11
    STK33 kinase inhibitor BRD-8899 has no effect on KRAS-dependent cancer cell viability

    STK33 kinase inhibitor BRD-8899 has no effect on KRAS-dependent cancer cell viability por Tuoping Luo, Kristina Masson, Jacob D. Jaffe, Whitney Silkworth, Nathan T. Ross, Christina Scherer, Claudia Scholl, Stefan Fröhling, Steven A. Carr, Andrew M. Stern, Stuart L. Schreiber, Todd R. Golub

    Publicado 2012
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  12. 12
    Phosphorylation of RAB7 by TBK1/IKKϵ Regulates Innate Immune Signaling in Triple-Negative Breast Cancer

    Phosphorylation of RAB7 by TBK1/IKKϵ Regulates Innate Immune Signaling in Triple-Negative Breast Cancer por Jessica Ritter, Zehua Zhu, Tran C. Thai, Navin R. Mahadevan, Philipp Mertins, Erik H. Knelson, Brandon Piel, Saemi Han, Jacob D. Jaffe, Steven A. Carr, David A. Barbie, Thanh U. Barbie

    Publicado 2019
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  13. 13
    Causal interactions from proteomic profiles: Molecular data meet pathway knowledge

    Causal interactions from proteomic profiles: Molecular data meet pathway knowledge por Özgün Babur, Augustin Luna, Anil Korkut, Funda Durupınar, Metin Can Siper, Uḡur Doḡrusöz, Alvaro Sebastian Vaca Jacome, Ryan Peckner, Karen E. Christianson, Jacob D. Jaffe, Paul T. Spellman, Joseph E. Aslan, Chris Sander, Emek Demir

    Publicado 2021
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  14. 14
    Down-syndrome-induced senescence disrupts the nuclear architecture of neural progenitors

    Down-syndrome-induced senescence disrupts the nuclear architecture of neural progenitors por Hiruy S. Meharena, Asaf Marco, Vishnu Dileep, Elana R. Lockshin, Grace Y. Akatsu, James Mullahoo, L. Ashley Watson, Tak Ko, Lindsey N. Guerin, Fatema Abdurrob, Shruthi Rengarajan, Malvina Papanastasiou, Jacob D. Jaffe, Li‐Huei Tsai

    Publicado 2022
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  15. 15
    Functional Proteomic Analysis of Repressive Histone Methyltransferase Complexes Reveals ZNF518B as a G9A Regulator*

    Functional Proteomic Analysis of Repressive Histone Methyltransferase Complexes Reveals ZNF518B as a G9A Regulator* por Verena Maier, Caitlin M. Feeney, Jordan E. Taylor, Amanda L. Creech, Jana Qiao, Attila Szántó, Partha Pratim Das, Nicholas Chevrier, Catherine Cifuentes‐Rojas, Stuart H. Orkin, Steven A. Carr, Jacob D. Jaffe, Philipp Mertins, Jeannie T. Lee

    Publicado 2015
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  16. 16
    Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers

    Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers por Joseph Rosenbluh, Johnathan Mercer, Yashaswi Shrestha, Rachel A. Oliver, Pablo Tamayo, John G. Doench, Itay Tirosh, Federica Piccioni, Ella Hartenian, Heiko Horn, Lọla Fagbami, David E. Root, Jacob D. Jaffe, Kasper Lage, Jesse S. Boehm, William C. Hahn

    Publicado 2016
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  17. 17
    A Curated Resource for Phosphosite-specific Signature Analysis

    A Curated Resource for Phosphosite-specific Signature Analysis por Karsten Krug, Philipp Mertins, Bin Zhang, Peter Hornbeck, Rajesh Raju, Rushdy Ahmad, Matthew J. Szucs, Filip Mundt, Dominique Forestier, Judit Jané‐Valbuena, Hasmik Keshishian, Michael A. Gillette, Pablo Tamayo, Jill P. Mesirov, Jacob D. Jaffe, StevenA. Carr, D.R. Mani

    Publicado 2018
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  18. 18
    The nucleosome acidic patch and H2A ubiquitination underlie mSWI/SNF recruitment in synovial sarcoma

    The nucleosome acidic patch and H2A ubiquitination underlie mSWI/SNF recruitment in synovial sarcoma por Matthew J. McBride, Nazar Mashtalir, Evan B. Winter, Hai T. Dao, Martin Filipovski, Andrew R. D’Avino, Hyuk‐Soo Seo, Neil T. Umbreit, Roodolph St. Pierre, Alfredo M. Valencia, Kristin Qian, Hayley Zullow, Jacob D. Jaffe, Sirano Dhe‐Paganon, Tom W. Muir, Cigall Kadoch

    Publicado 2020
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  19. 19
    HIF activation causes synthetic lethality between the <i>VHL</i> tumor suppressor and the <i>EZH1</i> histone methyltransferase

    HIF activation causes synthetic lethality between the <i>VHL</i> tumor suppressor and the <i>EZH1</i> histone methyltransferase por Abhishek A. Chakraborty, Eijiro Nakamura, Jun Qi, Amanda L. Creech, Jacob D. Jaffe, Joshiawa Paulk, Jesse Novak, Kshithija Nagulapalli, Samuel K. McBrayer, Glenn S. Cowley, Javier Pineda, Jiaxi Song, Yaoyu E. Wang, Steven A. Carr, David E. Root, Sabina Signoretti, James E. Bradner, William G. Kaelin

    Publicado 2017
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  20. 20
    Plasticity in patterns of histone modifications and chromosomal proteins in <i>Drosophila</i> heterochromatin

    Plasticity in patterns of histone modifications and chromosomal proteins in <i>Drosophila</i> heterochromatin por Nicole C. Riddle, Aki Minoda, Peter V. Kharchenko, Artyom A. Alekseyenko, Yuri B. Schwartz, Michael Tolstorukov, Andrey A. Gorchakov, Jacob D. Jaffe, Cameron Kennedy, Daniela Linder-Basso, Sally E. Peach, Gregory Shanower, Haiyan Zheng, Mitzi I. Kuroda, Vincenzo Pirrotta, Peter J. Park, Sarah C. R. Elgin, Gary H. Karpen

    Publicado 2010
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