نتائج البحث - Isobel D. Stewart

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  1. 1
    Plasma metabolites to profile pathways in noncommunicable disease multimorbidity

    Plasma metabolites to profile pathways in noncommunicable disease multimorbidity حسب Maik Pietzner, Isobel D. Stewart, Johannes Raffler, Kay‐Tee Khaw, Gregory Michelotti, Gabi Kastenmüller, Nicholas J. Wareham, Claudia Langenberg

    منشور في 2021
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  2. 2
    Meta-analysis investigating the role of interleukin-6 mediated inflammation in type 2 diabetes

    Meta-analysis investigating the role of interleukin-6 mediated inflammation in type 2 diabetes حسب Nicholas Bowker, Rupal Shah, Stephen J. Sharp, Jian’an Luan, Isobel D. Stewart, Eleanor Wheeler, Manuel A. R. Ferreira, Aris Baras, Nicholas J. Wareham, Claudia Langenberg, Luca A. Lotta

    منشور في 2020
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  3. 3
    Causal effects of maternal circulating amino acids on offspring birthweight: a Mendelian randomisation study

    Causal effects of maternal circulating amino acids on offspring birthweight: a Mendelian randomisation study حسب Jian Zhao, Isobel D. Stewart, Denis Baird, Dan Mason, John Wright, Jie Zheng, Tom R. Gaunt, David M. Evans, Rachel M. Freathy, Claudia Langenberg, Nicole M. Warrington, Debbie A. Lawlor, Maria Carolina Borges

    منشور في 2023
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  4. 4
    Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies

    Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies حسب Kieu Trinh, Simone Wahl, Johannes Raffler, Sophie Molnos, Michael Laimighofer, Jerzy Adamski, Karsten Suhre, Konstantin Strauch, Annette Peters, Christian Gieger, Claudia Langenberg, Isobel D. Stewart, Fabian J. Theis, Harald Grallert, Gabi Kastenmüller, Jan Krumsiek

    منشور في 2018
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    Artigo
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  5. 5
    Whole-exome sequencing identifies rare genetic variants associated with human plasma metabolites

    Whole-exome sequencing identifies rare genetic variants associated with human plasma metabolites حسب Lorenzo Bomba, Klaudia Walter, Qi Guo, Praveen Surendran, Kousik Kundu, Suraj S. Nongmaithem, Mohd Anisul Karim, Isobel D. Stewart, Claudia Langenberg, John Danesh, Emanuele Di Angelantonio, David J. Roberts, Willem H. Ouwehand, Ian Dunham, Adam S. Butterworth, Nicole Soranzo

    منشور في 2022
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  6. 6
    Integrated Analyses of Microbiome and Longitudinal Metabolome Data Reveal Microbial-Host Interactions on Sulfur Metabolism in Parkinson’s Disease

    Integrated Analyses of Microbiome and Longitudinal Metabolome Data Reveal Microbial-Host Interactions on Sulfur Metabolism in Parkinson’s Disease حسب Johannes Hertel, Amy C. Harms, Almut Heinken, Federico Baldini, Cyrille C. Thinnes, Enrico Glaab, Daniel A. Vasco, Maik Pietzner, Isobel D. Stewart, Nicholas J. Wareham, Claudia Langenberg, Claudia Trenkwalder, Rejko Krüger, Thomas Hankemeier, Ronan M. T. Fleming, Brit Mollenhauer, Ines Thiele

    منشور في 2019
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  7. 7
    Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases

    Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases حسب Yiheng Chen, Tianyuan Lu, U. Pettersson, Isobel D. Stewart, Guillaume Butler‐Laporte, Tomoko Nakanishi, Agustin Cerani, Kevin Y. H. Liang, Satoshi Yoshiji, Julian Daniel Sunday Willett, Chen‐Yang Su, Parminder Raina, Celia M.T. Greenwood, Yossi Farjoun, Vincenzo Forgetta, Claudia Langenberg, Sirui Zhou, Claes Ohlsson, J. Brent Richards

    منشور في 2023
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  8. 8
    Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity

    Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity حسب Luca A. Lotta, Jacek Mokrosiński, Edson Mendes de Oliveira, Chen Li, Stephen J. Sharp, Jian’an Luan, Bas Brouwers, V. Ayinampudi, Nicholas Bowker, Nicola D. Kerrison, Vasileios Kaimakis, Diana Hoult, Isobel D. Stewart, Eleanor Wheeler, Felix R. Day, John R. B. Perry, Claudia Langenberg, Nicholas J. Wareham, I. Sadaf Farooqi

    منشور في 2019
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  9. 9
    Mapping the proteo-genomic convergence of human diseases

    Mapping the proteo-genomic convergence of human diseases حسب Maik Pietzner, Eleanor Wheeler, Julia Carrasco-Zanini, Adrián Cortés, Mine Koprulu, Maria A. Wörheide, Erin Oerton, James Cook, Isobel D. Stewart, Nicola D. Kerrison, Jian’an Luan, Johannes Raffler, Matthias Arnold, Wiebke Arlt, Stephen O’Rahilly, Gabi Kastenmüller, Eric R. Gamazon, Aroon D. Hingorani, Robert A. Scott, Nicholas J. Wareham, Claudia Langenberg

    منشور في 2021
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  10. 10
    Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors

    Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors حسب Luca A. Lotta, Laura B. L. Wittemans, Verena Zuber, Isobel D. Stewart, Stephen J. Sharp, Jian’an Luan, Felix R. Day, Chen Li, Nicholas Bowker, Lina Cai, Emanuella De Lucia Rolfe, Kay‐Tee Khaw, John R. B. Perry, Stephen O’Rahilly, Robert A. Scott, David B. Savage, Stephen Burgess, Nicholas J. Wareham, Claudia Langenberg

    منشور في 2018
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  11. 11
    Association of Genetically Enhanced Lipoprotein Lipase–Mediated Lipolysis and Low-Density Lipoprotein Cholesterol–Lowering Alleles With Risk of Coronary Disease and Type 2 Diabetes

    Association of Genetically Enhanced Lipoprotein Lipase–Mediated Lipolysis and Low-Density Lipoprotein Cholesterol–Lowering Alleles With Risk of Coronary Disease and Type 2 Diabetes... حسب Luca A. Lotta, Isobel D. Stewart, Stephen J. Sharp, Felix R. Day, Stephen Burgess, Jian’an Luan, Nicholas Bowker, Lina Cai, Chen Li, Laura B. L. Wittemans, Nicola D. Kerrison, Kay‐Tee Khaw, Mark I. McCarthy, Stephen O’Rahilly, Robert A. Scott, David B. Savage, John R. B. Perry, Claudia Langenberg, Nicholas J. Wareham

    منشور في 2018
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  12. 12
    Assessing the causal association of glycine with risk of cardio-metabolic diseases

    Assessing the causal association of glycine with risk of cardio-metabolic diseases حسب Laura B. L. Wittemans, Luca A. Lotta, Clare Oliver‐Williams, Isobel D. Stewart, Praveen Surendran, Savita Karthikeyan, Felix R. Day, Albert Koulman, Fumiaki Imamura, Lingyao Zeng, Jeanette Erdmann, Heribert Schunkert, Kay‐Tee Khaw, Julian L. Griffin, Nita G. Forouhi, Robert A. Scott, Angela Wood, Stephen Burgess, Joanna M. M. Howson, John Danesh, Nicholas J. Wareham, Adam S. Butterworth, Claudia Langenberg

    منشور في 2019
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  13. 13
    Metabolomic profiling reveals extensive adrenal suppression due to inhaled corticosteroid therapy in asthma

    Metabolomic profiling reveals extensive adrenal suppression due to inhaled corticosteroid therapy in asthma حسب Priyadarshini Kachroo, Isobel D. Stewart, Rachel S. Kelly, Meryl Stav, Kevin Mendez, Amber Dahlin, Djøra I. Soeteman, Su H. Chu, Mengna Huang, Margaret Cote, Hanna Knihtilä, Kathleen Lee‐Sarwar, Michael J. McGeachie, Alberta L. Wang, Ann Chen Wu, Yamini V. Virkud, Pei Zhang, Nicholas J. Wareham, Elizabeth W. Karlson, Craig E. Wheelock, Clary B. Clish, Scott T. Weiss, Claudia Langenberg, Jessica Lasky‐Su

    منشور في 2022
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  14. 14
    Mitochondrial DNA variants modulate N-formylmethionine, proteostasis and risk of late-onset human diseases

    Mitochondrial DNA variants modulate N-formylmethionine, proteostasis and risk of late-onset human diseases حسب Na Cai, Aurora Gómez-Durán, Ekaterina Yonova‐Doing, Kousik Kundu, A I Burgess, Zoe Golder, Claudia Calabrese, Marc Jan Bonder, Marta Camacho, Rachael A. Lawson, Lixin Li, Caroline H. Williams‐Gray, Emanuele Di Angelantonio, David J. Roberts, Nick Watkins, Willem H. Ouwehand, Adam S. Butterworth, Isobel D. Stewart, Maik Pietzner, Nicholas J. Wareham, Claudia Langenberg, John Danesh, Klaudia Walter, Peter M. Rothwell, Joanna M. M. Howson, Oliver Stegle, Patrick F. Chinnery, Nicole Soranzo

    منشور في 2021
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  15. 15
    Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis

    Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis حسب Luca A. Lotta, Robert A. Scott, Stephen J. Sharp, Stephen Burgess, Jian’an Luan, Therese Tillin, Amand F. Schmidt, Fumiaki Imamura, Isobel D. Stewart, John R. B. Perry, Luke Marney, Albert Koulman, Edward D. Karoly, Nita G. Forouhi, Rasmus J. O. Sjögren, Erik Näslund, Juleen R. Zierath, Anna Krook, David B. Savage, Julian L. Griffin, Nish Chaturvedi, Aroon D. Hingorani, Kay‐Tee Khaw, Inês Barroso, Mark I. McCarthy, Stephen O’Rahilly, Nicholas J. Wareham, Claudia Langenberg

    منشور في 2016
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  16. 16
    Epigenome-Wide Association Study of Incident Type 2 Diabetes in a British Population: EPIC-Norfolk Study

    Epigenome-Wide Association Study of Incident Type 2 Diabetes in a British Population: EPIC-Norfolk Study حسب Alexia Cardona, Felix R. Day, John R. B. Perry, Marie Loh, Audrey Y. Chu, Benjamin Lehne, Dirk S. Paul, Luca A. Lotta, Isobel D. Stewart, Nicola D. Kerrison, Robert A. Scott, Kay‐Tee Khaw, Nita G. Forouhi, Claudia Langenberg, Chunyu Liu, Michael Mendelson, Daniel Levy, Stephan Beck, Richard David Leslie, Josée Dupuis, James B. Meigs, Jaspal S. Kooner, Jussi Pihlajamäki, Allan Vaag, Alexander Perfilyev, Charlotte Ling, Marie‐France Hivert, John C. Chambers, Nicholas J. Wareham, Ken K. Ong

    منشور في 2019
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  17. 17
    A cross-platform approach identifies genetic regulators of human metabolism and health

    A cross-platform approach identifies genetic regulators of human metabolism and health حسب Luca A. Lotta, Maik Pietzner, Isobel D. Stewart, Laura B. L. Wittemans, Chen Li, Roberto Bonelli, Johannes Raffler, Emma K. Biggs, Clare Oliver‐Williams, Victoria P.W. Auyeung, Jian’an Luan, Eleanor Wheeler, Ellie Paige, Praveen Surendran, Gregory Michelotti, Robert A. Scott, Stephen Burgess, Verena Zuber, Eleanor Sanderson, Albert Koulman, Fumiaki Imamura, Nita G. Forouhi, Kay‐Tee Khaw, Julian L. Griffin, Angela Wood, Gabi Kastenmüller, John Danesh, Adam S. Butterworth, Fiona M. Gribble, Frank Reimann, Melanie Bahlo, Eric B. Fauman, Nicholas J. Wareham, Claudia Langenberg

    منشور في 2021
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  18. 18
    Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance

    Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance حسب Luca A. Lotta, Pawan Gulati, Felix R. Day, Felicity Payne, Halit Ongen, Martijn van de Bunt, Kyle J. Gaulton, John D. Eicher, Stephen J. Sharp, Jian’an Luan, Emanuella De Lucia Rolfe, Isobel D. Stewart, Eleanor Wheeler, Sara M. Willems, Claire Adams, Hanieh Yaghootkar, Nita G. Forouhi, Kay‐Tee Khaw, Andrew D. Johnson, Robert K. Semple, Timothy M. Frayling, John R. B. Perry, Emmanouil V. Dermitzakis, Mark I. McCarthy, Inês Barroso, Nicholas J. Wareham, David B. Savage, Claudia Langenberg, Stephen O’Rahilly, Robert A. Scott

    منشور في 2016
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  19. 19
    Rare and common genetic determinants of metabolic individuality and their effects on human health

    Rare and common genetic determinants of metabolic individuality and their effects on human health حسب Praveen Surendran, Isobel D. Stewart, Victoria P. W. Au Yeung, Maik Pietzner, Johannes Raffler, Maria A. Wörheide, Chen Li, Rebecca F. Smith, Laura B. L. Wittemans, Lorenzo Bomba, Cristina Menni, Jonas Zierer, Niccolò Rossi, Patricia A. Sheridan, Nicholas A. Watkins, Massimo Mangino, Pirro G. Hysi, Emanuele Di Angelantonio, Mario Falchi, Tim D. Spector, Nicole Soranzo, Gregory Michelotti, Wiebke Arlt, Luca A. Lotta, Spiros Denaxas, Harry Hemingway, Eric R. Gamazon, Joanna M. M. Howson, Angela Wood, John Danesh, Nicholas J. Wareham, Gabi Kastenmüller, Eric B. Fauman, Karsten Suhre, Adam S. Butterworth, Claudia Langenberg

    منشور في 2022
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  20. 20
    Circulating metabolites modulated by diet are associated with depression

    Circulating metabolites modulated by diet are associated with depression حسب Ashley van der Spek, Isobel D. Stewart, Brigitte Kühnel, Maik Pietzner, Tahani Alshehri, Friederike Gauß, Pirro G. Hysi, Siamak MahmoudianDehkordi, Almut Heinken, Annemarie I. Luik, Karl-Heinz Ladwig, Gabi Kastenmüller, Cristina Menni, Johannes Hertel, M. Arfan Ikram, Renée de Mutsert, Karsten Suhre, Christian Gieger, Konstantin Strauch, Henry Völzke, Thomas Meitinger, Massimo Mangino, Antònia Flaquer, Mélanie Waldenberger, Annette Peters, Ines Thiele, Rima Kaddurah‐Daouk, Boadie W. Dunlop, Frits R. Rosendaal, Nicholas J. Wareham, Tim D. Spector, Sonja Kunze, Hans J. Grabe, Dennis O. Mook‐Kanamori, Claudia Langenberg, Cornelia M. van Duijn, Najaf Amin

    منشور في 2023
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