Risultati della ricerca - Isabelle Plo

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  1. 1
    Recent advances in understanding myelofibrosis and essential thrombocythemia

    Recent advances in understanding myelofibrosis and essential thrombocythemia di William Vainchenker, Stefan N. Constantinescu, Isabelle Plo

    Pubblicazione 2016
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  2. 2
    Defects in XRCC4 and KU80 differentially affect the joining of distal nonhomologous ends

    Defects in XRCC4 and KU80 differentially affect the joining of distal nonhomologous ends di Josée Guirouilh‐Barbat, Emilie Rass, Isabelle Plo, Pascale Bertrand, Bernard S. López

    Pubblicazione 2007
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  3. 3
    AKT1 Inhibits Homologous Recombination by Inducing Cytoplasmic Retention of BRCA1 and RAD51

    AKT1 Inhibits Homologous Recombination by Inducing Cytoplasmic Retention of BRCA1 and RAD51 di Isabelle Plo, Corentin Laulier, Laurent Gauthier, Fabienne Lebrun, Fabien Calvo, Bernard S. López

    Pubblicazione 2008
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  4. 4
    Genetic Alterations of the Thrombopoietin/MPL/JAK2 Axis Impacting Megakaryopoiesis

    Genetic Alterations of the Thrombopoietin/MPL/JAK2 Axis Impacting Megakaryopoiesis di Isabelle Plo, Christine Bellanné‐Chantelot, Matthieu Mosca, Stefania Mazzi, Caroline Marty, William Vainchenker

    Pubblicazione 2017
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  5. 5
    JAK inhibitors for the treatment of myeloproliferative neoplasms and other disorders

    JAK inhibitors for the treatment of myeloproliferative neoplasms and other disorders di William Vainchenker, Emilie Leroy, Laure Gilles, Caroline Marty, Isabelle Plo, Stefan N. Constantinescu

    Pubblicazione 2018
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  6. 6
    Induced pluripotent stem cells and hematological malignancies: A powerful tool for disease modeling and drug development

    Induced pluripotent stem cells and hematological malignancies: A powerful tool for disease modeling and drug development di Alessandro Donada, Francesca Basso‐Valentina, Brahim Arkoun, Bárbara da Costa Reis Monte-Mór, Isabelle Plo, Hana Raslová

    Pubblicazione 2020
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  7. 7
    BRCA1-Ku80 Protein Interaction Enhances End-joining Fidelity of Chromosomal Double-strand Breaks in the G1 Phase of the Cell Cycle

    BRCA1-Ku80 Protein Interaction Enhances End-joining Fidelity of Chromosomal Double-strand Breaks in the G1 Phase of the Cell Cycle di Guochun Jiang, Isabelle Plo, Tong Wang, Mohammad Aminur Rahman, Ju Hwan Cho, Eddy S. Yang, Bernard S. López, Fen Xia

    Pubblicazione 2013
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  8. 8
    JAK2 stimulates homologous recombination and genetic instability: potential implication in the heterogeneity of myeloproliferative disorders

    JAK2 stimulates homologous recombination and genetic instability: potential implication in the heterogeneity of myeloproliferative disorders di Isabelle Plo, Mayuka Nakatake, Laurent Malivert, Jean‐Pierre de Villartay, Stéphane Giraudier, Jean‐Luc Villeval, Lisa Wiesmüller, William Vainchenker

    Pubblicazione 2008
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  9. 9
    JAK2V617F negatively regulates p53 stabilization by enhancing MDM2 via La expression in myeloproliferative neoplasms

    JAK2V617F negatively regulates p53 stabilization by enhancing MDM2 via La expression in myeloproliferative neoplasms di Mayuka Nakatake, Bárbara da Costa Reis Monte-Mór, Najet Debili, Nicole Casadevall, Vincent Ribrag, Éric Solary, William Vainchenker, Isabelle Plo

    Pubblicazione 2011
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  10. 10
    Differential Contributions of STAT5A and STAT5B to Stress Protection and Tyrosine Kinase Inhibitor Resistance of Chronic Myeloid Leukemia Stem/Progenitor Cells

    Differential Contributions of STAT5A and STAT5B to Stress Protection and Tyrosine Kinase Inhibitor Resistance of Chronic Myeloid Leukemia Stem/Progenitor Cells di Luana Casetti, Severine Martin‐Lannerée, Imen Najjar, Isabelle Plo, Sylvie Augé, Lydia Roy, Jean‐Claude Chomel, Evelyne Lauret, Ali G. Turhan, Isabelle Dusanter‐Fourt

    Pubblicazione 2013
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  11. 11
    Calreticulin mutants in mice induce an MPL-dependent thrombocytosis with frequent progression to myelofibrosis

    Calreticulin mutants in mice induce an MPL-dependent thrombocytosis with frequent progression to myelofibrosis di Caroline Marty, C. Pecquet, Harini Nivarthi, Mira El-Khoury, Ilyas Chachoua, M Tulliez, Jean‐Luc Villeval, Hana Raslová, Róbert Královics, Stefan N. Constantinescu, Isabelle Plo, William Vainchenker

    Pubblicazione 2015
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  12. 12
    P53 activation inhibits all types of hematopoietic progenitors and all stages of megakaryopoiesis

    P53 activation inhibits all types of hematopoietic progenitors and all stages of megakaryopoiesis di Emna Mahfoudhi, Larissa Lordier, Caroline Marty, Jiajia Pan, Anita Roy, Lydia Roy, Philippe Rameau, Salem Abbès, Najet Debili, Hana Raslová, Yunhua Chang, Laurent Debüssche, William Vainchenker, Isabelle Plo

    Pubblicazione 2016
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  13. 13
    An activating mutation in the <i>CSF3R</i> gene induces a hereditary chronic neutrophilia

    An activating mutation in the <i>CSF3R</i> gene induces a hereditary chronic neutrophilia di Isabelle Plo, Yanyan Zhang, Jean‐Pierre Le Couedic, Mayuka Nakatake, Jean-Michel Boulet, Miki Itaya, Steven O. Smith, Najet Debili, Stefan N. Constantinescu, William Vainchenker, Fawzia Louache, Stéphane de Botton

    Pubblicazione 2009
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  14. 14
    Disease Phenotype and Clonal Amplification in Calreticulin del52 and ins5 Knock-in Mice Are Dependent on the Type of Mutations and Gene Dosage

    Disease Phenotype and Clonal Amplification in Calreticulin del52 and ins5 Knock-in Mice Are Dependent on the Type of Mutations and Gene Dosage di Camélia Benlabiod, Maira da Costa Cacemiro, Thomas Balligand, Barbara Panneau-Schmaltz, Delphine Muller, Laure Touchard, Patrick Gonin, Jean‐Luc Villeval, Stefan N. Constantinescu, Hana Raslová, William Vainchenker, Isabelle Plo, Caroline Marty

    Pubblicazione 2019
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  15. 15
    Knock-in of murine Calr del52 induces essential thrombocythemia with slow-rising dominance in mice and reveals key role of Calr exon 9 in cardiac development

    Knock-in of murine Calr del52 induces essential thrombocythemia with slow-rising dominance in mice and reveals key role of Calr exon 9 in cardiac development di Thomas Balligand, Younès Achouri, C. Pecquet, Gilles Gaudray, Didier Colau, Eva Hug, Yacine Rahmani, Vincent Stroobant, Isabelle Plo, William Vainchenker, Róbert Královics, Benoı̂t J. Van den Eynde, Jean‐Philippe Defour, Stefan N. Constantinescu

    Pubblicazione 2019
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  16. 16
    TET2 haploinsufficiency alters reprogramming into induced pluripotent stem cells

    TET2 haploinsufficiency alters reprogramming into induced pluripotent stem cells di Lise Secardin, Cintia Elisabeth Gomez Limia, Antonio Di Stefano, Martín Bonamino, Joseph Saliba, Keisuke Kataoka, Stevens K. Rehen, Hana Raslová, Caroline Marty, Seishi Ogawa, William Vainchenker, Bárbara da Costa Reis Monte-Mór, Isabelle Plo

    Pubblicazione 2020
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  17. 17
    CXCR4/CXCL12 axis counteracts hematopoietic stem cell exhaustion through selective protection against oxidative stress

    CXCR4/CXCL12 axis counteracts hematopoietic stem cell exhaustion through selective protection against oxidative stress di Yanyan Zhang, Mallorie Dépond, Liang He, Adlen Foudi, Edward Owusu Kwarteng, Evelyne Lauret, Isabelle Plo, Christophe Desterke, Philippe Dessen, Nobutaka Fujii, Paule Opolon, Olivier Hérault, Éric Solary, William Vainchenker, V. Joulin, Fawzia Louache, M. Wittner

    Pubblicazione 2016
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  18. 18
    Defective interaction of mutant calreticulin and SOCE in megakaryocytes from patients with myeloproliferative neoplasms

    Defective interaction of mutant calreticulin and SOCE in megakaryocytes from patients with myeloproliferative neoplasms di Christian A. Di Buduo, Vittorio Abbonante, Caroline Marty, Francesco Moccia, Elisa Rumi, Daniela Pietra, Paolo M. Soprano, Dmitry Lim, Daniele Cattaneo, Alessandra Iurlo, Umberto Gianelli, Giovanni Barosi, Vittorio Rosti, Isabelle Plo, Mario Cazzola, Alessandra Balduini

    Pubblicazione 2019
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  19. 19
    Discovery of INCA033989, a Monoclonal Antibody That Selectively Antagonizes Mutant Calreticulin Oncogenic Function in Myeloproliferative Neoplasms (MPNs)

    Discovery of INCA033989, a Monoclonal Antibody That Selectively Antagonizes Mutant Calreticulin Oncogenic Function in Myeloproliferative Neoplasms (MPNs) di Edimara S. Reis, Rebecca A. Buonpane, Hamza Celik, Caroline Marty, Angela Lei, Fatoumata Jobe, Mark Rupar, Yue Zhang, Darlise DiMatteo, Rahel Awdew, William Vainchenker, Jing Zhou, Ian S. Hitchcock, Isabelle Plo, Horacio Nastri, Patrick A. Mayes

    Pubblicazione 2022
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  20. 20
    Analysis of the Ten-Eleven Translocation 2 (TET2) gene in familial myeloproliferative neoplasms

    Analysis of the Ten-Eleven Translocation 2 (TET2) gene in familial myeloproliferative neoplasms di Cécile Saint‐Martin, Gwendoline Leroy, François Delhommeau, G. Panelatti, Sabrina Dupont, Chloé James, Isabelle Plo, Dominique Bordessoule, Christine Chomienne, André Delannoy, Alain Devidas, M Gardembas-Pain, Françoise Isnard, Yves Plumelle, Olivier Bernard, William Vainchenker, A Najman, Christine Bellanné‐Chantelot

    Pubblicazione 2009
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