Resultados de procura - Isabelle Leclerc

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  1. 1
    The AMP-regulated kinase family: Enigmatic targets for diabetes therapy

    The AMP-regulated kinase family: Enigmatic targets for diabetes therapy por Guy A. Rutter, Isabelle Leclerc

    Publicado 2008
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  2. 2
    AMP-Activated Protein Kinase: A New Beta-Cell Glucose Sensor?

    AMP-Activated Protein Kinase: A New Beta-Cell Glucose Sensor? por Isabelle Leclerc, Guy A. Rutter

    Publicado 2004
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  3. 3
    Roles of 5′-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis

    Roles of 5′-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis por Guy A. Rutter, Gabriela da Silva Xavier, Isabelle Leclerc

    Publicado 2003
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  4. 4
    Glucose-Induced Nuclear Shuttling of ChREBP Is Mediated by Sorcin and Ca2+ Ions in Pancreatic β-Cells

    Glucose-Induced Nuclear Shuttling of ChREBP Is Mediated by Sorcin and Ca2+ Ions in Pancreatic β-Cells por Nafeesa A. Noordeen, Gargi Meur, Guy A. Rutter, Isabelle Leclerc

    Publicado 2012
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  5. 5
    5′-AMP-activated Protein Kinase Controls Insulin-containing Secretory Vesicle Dynamics

    5′-AMP-activated Protein Kinase Controls Insulin-containing Secretory Vesicle Dynamics por Takashi Tsuboi, Gabriela da Silva Xavier, Isabelle Leclerc, Guy A. Rutter

    Publicado 2003
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  6. 6
    Over-expression of AMP-activated protein kinase impairs pancreatic β-cell function in vivo

    Over-expression of AMP-activated protein kinase impairs pancreatic β-cell function in vivo por Sarah Richards, Laura E. Parton, Isabelle Leclerc, Guy A. Rutter, Richard Smith

    Publicado 2005
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  7. 7
    Hepatocyte Nuclear Factor-4α Involved in Type 1 Maturity-Onset Diabetes of the Young Is a Novel Target of AMP-Activated Protein Kinase

    Hepatocyte Nuclear Factor-4α Involved in Type 1 Maturity-Onset Diabetes of the Young Is a Novel Target of AMP-Activated Protein Kinase por Isabelle Leclerc, Claudia Lenzner, Laurence Gourdon, Sophie Vaulont, Axel Kahn, Benoı̂t Viollet

    Publicado 2001
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  8. 8
    ChREBP binding to fatty acid synthase and L-type pyruvate kinase genes is stimulated by glucose in pancreatic β-cells

    ChREBP binding to fatty acid synthase and L-type pyruvate kinase genes is stimulated by glucose in pancreatic β-cells por Gabriela da Silva Xavier, Guy A. Rutter, Frédérique Diraison, Chrysovalantis Andreolas, Isabelle Leclerc

    Publicado 2006
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  9. 9
    AMP-activated protein kinase regulates glucagon secretion from mouse pancreatic alpha cells

    AMP-activated protein kinase regulates glucagon secretion from mouse pancreatic alpha cells por Isabelle Leclerc, Guoqiang Sun, Christina Morris, Elisa Fernández‐Millán, Moffat Nyirenda, Guy A. Rutter

    Publicado 2010
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  10. 10
    Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression

    Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression por Gabriela da Silva Xavier, Isabelle Leclerc, Anikó Váradi, Takashi Tsuboi, S K Moule, Guy A. Rutter

    Publicado 2003
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  11. 11
    Local and regional control of calcium dynamics in the pancreatic islet

    Local and regional control of calcium dynamics in the pancreatic islet por Guy A. Rutter, David J. Hodson, Pauline Chabosseau, Elizabeth Haythorne, Timothy J. Pullen, Isabelle Leclerc

    Publicado 2017
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  12. 12
    Over-expression of sterol-regulatory-element-binding protein-1c (SREBP1c) in rat pancreatic islets induces lipogenesis and decreases glucose-stimulated insulin release: modulation by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR)

    Over-expression of sterol-regulatory-element-binding protein-1c (SREBP1c) in rat pancreatic islets induces lipogenesis and decreases glucose-stimulated insulin release: modulation... por Frédérique Diraison, Laura E. Parton, Pascal Ferré, Fabienne Foufelle, Celia P. Briscoe, Isabelle Leclerc, Guy A. Rutter

    Publicado 2004
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  13. 13
    Impaired glucose homeostasis in transgenic mice expressing the human transient neonatal diabetes mellitus locus, TNDM

    Impaired glucose homeostasis in transgenic mice expressing the human transient neonatal diabetes mellitus locus, TNDM por Dan Ma, Julian Hamilton‐Shield, Wendy Dean, Isabelle Leclerc, Claude Knauf, Rémy Burcelin, Guy A. Rutter, Gavin Kelsey

    Publicado 2004
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  14. 14
    Impaired glucose homeostasis in transgenic mice expressing the human transient neonatal diabetes mellitus locus, TNDM

    Impaired glucose homeostasis in transgenic mice expressing the human transient neonatal diabetes mellitus locus, TNDM por Dan Ma, Julian Hamilton‐Shield, Wendy Dean, Isabelle Leclerc, Claude Knauf, Rémy Burcelin, Guy A. Rutter, Gavin Kelsey

    Publicado 2004
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  15. 15
    Loss of Brain Volume in Endogenous Cushing’s Syndrome and Its Reversibility after Correction of Hypercortisolism

    Loss of Brain Volume in Endogenous Cushing’s Syndrome and Its Reversibility after Correction of Hypercortisolism por Isabelle Bourdeau, Céline Bard, Bernard Noël, Isabelle Leclerc, Marie‐Pierre Cordeau, Manon Bélair, Jacques Lesage, Lucie Lafontaine, André Lacroix

    Publicado 2002
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  16. 16
    Role of AMP-activated protein kinase in the regulation by glucose of islet beta cell gene expression

    Role of AMP-activated protein kinase in the regulation by glucose of islet beta cell gene expression por Gabriela da Silva Xavier, Isabelle Leclerc, Ian P. Salt, Bruno Doiron, D. Grahame Hardie, Axel Kahn, Guy A. Rutter

    Publicado 2000
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  17. 17
    LKB1 deletion with the <i>RIP2.Cre</i> transgene modifies pancreatic β-cell morphology and enhances insulin secretion in vivo

    LKB1 deletion with the <i>RIP2.Cre</i> transgene modifies pancreatic β-cell morphology and enhances insulin secretion in vivo por Gao Sun, Andrei I. Tarasov, James McGinty, Paul M. W. French, Angela McDonald, Isabelle Leclerc, Guy A. Rutter

    Publicado 2010
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  18. 18
    Hypothalamic AMP-Activated Protein Kinase Regulates Glucose Production

    Hypothalamic AMP-Activated Protein Kinase Regulates Glucose Production por Clair S. Yang, Carol Lam, Madhu Chari, Grace W.C. Cheung, Andrea Kokorovic, Gao Sun, Isabelle Leclerc, Guy A. Rutter, Tony K.T. Lam

    Publicado 2010
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  19. 19
    Carbohydrate-Responsive Element-Binding Protein (ChREBP) Is a Negative Regulator of ARNT/HIF-1β Gene Expression in Pancreatic Islet β-Cells

    Carbohydrate-Responsive Element-Binding Protein (ChREBP) Is a Negative Regulator of ARNT/HIF-1β Gene Expression in Pancreatic Islet β-Cells por Nafeesa A. Noordeen, Tarnjit K. Khera, Gao Sun, E. Rebecca Longbottom, Timothy J. Pullen, Gabriela da Silva Xavier, Guy A. Rutter, Isabelle Leclerc

    Publicado 2009
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  20. 20
    The transcription factor Pax6 is required for pancreatic β cell identity, glucose-regulated ATP synthesis, and Ca2+ dynamics in adult mice

    The transcription factor Pax6 is required for pancreatic β cell identity, glucose-regulated ATP synthesis, and Ca2+ dynamics in adult mice por Ryan K. Mitchell, Marie‐Sophie Nguyen‐Tu, Pauline Chabosseau, Rebecca Callingham, Timothy J. Pullen, Rebecca Cheung, Isabelle Leclerc, David J. Hodson, Guy A. Rutter

    Publicado 2017
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