Canlyniadau Chwilio - Isabel Nájera
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Significance of amino acid variation at human immunodeficiency virus type 1 reverse transcriptase residue 210 for zidovudine susceptibility gan P. Richard Harrigan, I. Kinghorn, Stuart Bloor, Sharon D. Kemp, Isabel Nájera, Arinder Kohli, Brendan Larder
Cyhoeddwyd 1996Artigo -
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Resistance Profile of the Human Immunodeficiency Virus Type 1 Reverse Transcriptase Inhibitor Abacavir (1592U89) after Monotherapy and Combination Therapy gan P. Richard Harrigan, Chris Stone, Phillip Griffin, Isabel Nájera, Stuart Bloor, Sharon D. Kemp, Margaret Tisdale, Brendan Larder
Cyhoeddwyd 2000Artigo -
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Pol gene quasispecies of human immunodeficiency virus: mutations associated with drug resistance in virus from patients undergoing no drug therapy gan Isabel Nájera, África Holguín, Miguel E. Quiñones‐Mateu, María Ángeles Muñoz‐Fernández, R Nájera, Cecilio López‐Galíndez, Esteban Domingo
Cyhoeddwyd 1995Artigo -
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Existence of hepatitis C virus NS5B variants naturally resistant to non-nucleoside, but not to nucleoside, polymerase inhibitors among untreated patients gan Sophie Le Pogam, A. Seshaadri, Alan Kosaka, Stephan Chiu, Hyunsoon Kang, Song Hu, Sonal Rajyaguru, Julian Symons, N. Cammack, Isabel Nájera
Cyhoeddwyd 2008Artigo -
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The Hepatitis C Virus Replicon Presents a Higher Barrier to Resistance to Nucleoside Analogs than to Nonnucleoside Polymerase or Protease Inhibitors gan Matthew F. McCown, Sonal Rajyaguru, Sophie Le Pogam, Samir Ali, Wen-Rong Jiang, Hyunsoon Kang, Julian Symons, Nick Cammack, Isabel Nájera
Cyhoeddwyd 2008Artigo -
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Combinations of Oseltamivir and T-705 Extend the Treatment Window for Highly Pathogenic Influenza A(H5N1) Virus Infection in Mice gan Bindumadhav M. Marathe, Sook‐San Wong, Peter Vogel, Fernando García-Alcalde, Robert G. Webster, Richard J. Webby, Isabel Nájera, Elena A. Govorkova
Cyhoeddwyd 2016Artigo -
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A Novel Endonuclease Inhibitor Exhibits Broad-Spectrum Anti-Influenza Virus Activity <i>In Vitro</i> gan Jeremy C. Jones, Bindumadhav M. Marathe, C. Lerner, Lukas M. Kreis, Rodolfo Gasser, Philippe Noriel Q. Pascua, Isabel Nájera, Elena A. Govorkova
Cyhoeddwyd 2016Artigo -
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In Vivo Emergence of a Novel Mutant L159F/L320F in the NS5B Polymerase Confers Low-Level Resistance to the HCV Polymerase Inhibitors Mericitabine and Sofosbuvir gan Xiao Tong, Sophie Le Pogam, Lewyn Li, Kristin Haines, Katherine Piso, Victoria A. Baronas, Junmei Yan, Sung‐Sau So, Klaus Klumpp, Isabel Nájera
Cyhoeddwyd 2013Artigo -
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RG7128 Alone or in Combination with Pegylated Interferon‐α2a and Ribavirin Prevents Hepatitis C Virus (HCV) Replication and Selection of Resistant Variants in HCV‐Infected Patients... gan Sophie Le Pogam, A. Seshaadri, Aren Ewing, Hyunsoon Kang, Alan Kosaka, Junmei Yan, M. Michelle Berrey, B. Symonds, Abel De La Rosa, Nick Cammack, Isabel Nájera
Cyhoeddwyd 2010Artigo -
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Selected Replicon Variants with Low-Level In Vitro Resistance to the Hepatitis C Virus NS5B Polymerase Inhibitor PSI-6130 Lack Cross-Resistance with R1479 gan Samir Ali, Vincent Lévêque, Sophie Le Pogam, Han Ma, Friederike Philipp, Nicole Inocencio, Mark Smith, André Alker, Hyunsoon Kang, Isabel Nájera, Klaus Klumpp, Julian Symons, Nick Cammack, Wen-Rong Jiang
Cyhoeddwyd 2008Artigo -
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R1626 plus peginterferon Alfa-2a provides potent suppression of hepatitis C virus RNA and significant antiviral synergy in combination with ribavirin gan Paul J. Pockros, David R. Nelson, Eliot Godofsky, M. Rodríguez‐Torres, Gregory T. Everson, Michael Fried, Reem Ghalib, Stephen A. Harrison, Lisa M. Nyberg, Mitchell L. Shiffman, Isabel Nájera, Anna Chan, George Hill
Cyhoeddwyd 2008Artigo -
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Selection and Characterization of Replicon Variants Dually Resistant to Thumb- and Palm-Binding Nonnucleoside Polymerase Inhibitors of the Hepatitis C Virus gan Sophie Le Pogam, Hyunsoon Kang, Seth F. Harris, Vincent Lévêque, Anthony M. Giannetti, Samir Ali, Wen-Rong Jiang, Sonal Rajyaguru, Gisele Tavares, Connie Oshiro, Than Hendricks, Klaus Klumpp, Julian Symons, Michelle F. Browner, Nick Cammack, Isabel Nájera
Cyhoeddwyd 2006Artigo -
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Slow Binding Inhibition and Mechanism of Resistance of Non-nucleoside Polymerase Inhibitors of Hepatitis C Virus gan Julie Q. Hang, Yanli Yang, Seth F. Harris, Vincent Lévêque, Hannah J. Whittington, Sonal Rajyaguru, Gloria Ao-Ieong, Matthew F. McCown, April Wong, Anthony M. Giannetti, Sophie Le Pogam, Francisco X. Talamás, Nick Cammack, Isabel Nájera, Klaus Klumpp
Cyhoeddwyd 2009Artigo -
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Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms gan Zheng Zhou, Taishan Hu, Xue Zhou, Steffen Wildum, Fernando García-Alcalde, Zhiheng Xu, Daitze Wu, Yi Mao, Xiao‐Jun Tian, Yuan Zhou, Fang Shen, Zhisen Zhang, Guozhi Tang, Isabel Nájera, Guang Yang, Hong C. Shen, John A. T. Young, Na Qin
Cyhoeddwyd 2017Artigo
Offerynnau Chwilio:
Pynciau Perthynol
Biology
Virology
Virus
Gene
Hepatitis C virus
Hepacivirus
Biochemistry
Genetics
Medicine
Polymerase
Enzyme
NS5B
Mutant
Polymerase chain reaction
Resistance mutation
Reverse transcriptase
Chemistry
Molecular biology
Plasmid
Replicon
Ribavirin
Viral replication
Influenza A virus
Mutation
Pharmacology
Viral quasispecies
Combination therapy
Environmental health
Neuraminidase
Nucleoside