Výsledky vyhledávání - Isabel Nájera

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  1. 1
    GT-1a or GT-1b Subtype-Specific Resistance Profiles for Hepatitis C Virus Inhibitors Telaprevir and HCV-796

    GT-1a or GT-1b Subtype-Specific Resistance Profiles for Hepatitis C Virus Inhibitors Telaprevir and HCV-796 Autor Matthew F. McCown, Sonal Rajyaguru, Simran Kular, Nick Cammack, Isabel Nájera

    Vydáno 2009
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  2. 2
    Essential Role of the N-terminal Domain in the Regulation of RIG-I ATPase Activity

    Essential Role of the N-terminal Domain in the Regulation of RIG-I ATPase Activity Autor Peter Gee, Pong Kian Chua, Jirair Gevorkyan, Klaus Klumpp, Isabel Nájera, David C. Swinney, Jérôme Deval

    Vydáno 2008
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  3. 3
    Significance of amino acid variation at human immunodeficiency virus type 1 reverse transcriptase residue 210 for zidovudine susceptibility

    Significance of amino acid variation at human immunodeficiency virus type 1 reverse transcriptase residue 210 for zidovudine susceptibility Autor P. Richard Harrigan, I. Kinghorn, Stuart Bloor, Sharon D. Kemp, Isabel Nájera, Arinder Kohli, Brendan Larder

    Vydáno 1996
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  4. 4
    Resistance Profile of the Human Immunodeficiency Virus Type 1 Reverse Transcriptase Inhibitor Abacavir (1592U89) after Monotherapy and Combination Therapy

    Resistance Profile of the Human Immunodeficiency Virus Type 1 Reverse Transcriptase Inhibitor Abacavir (1592U89) after Monotherapy and Combination Therapy Autor P. Richard Harrigan, Chris Stone, Phillip Griffin, Isabel Nájera, Stuart Bloor, Sharon D. Kemp, Margaret Tisdale, Brendan Larder

    Vydáno 2000
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  5. 5
    Identification of the I38T PA Substitution as a Resistance Marker for Next-Generation Influenza Virus Endonuclease Inhibitors

    Identification of the I38T PA Substitution as a Resistance Marker for Next-Generation Influenza Virus Endonuclease Inhibitors Autor Jeremy C. Jones, Gyanendra Kumar, Subrata Barman, Isabel Nájera, Stephen W. White, Richard J. Webby, Elena A. Govorkova

    Vydáno 2018
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  6. 6
    Pol gene quasispecies of human immunodeficiency virus: mutations associated with drug resistance in virus from patients undergoing no drug therapy

    Pol gene quasispecies of human immunodeficiency virus: mutations associated with drug resistance in virus from patients undergoing no drug therapy Autor Isabel Nájera, África Holguín, Miguel E. Quiñones‐Mateu, María Ángeles Muñoz‐Fernández, R Nájera, Cecilio López‐Galíndez, Esteban Domingo

    Vydáno 1995
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  7. 7
    Existence of hepatitis C virus NS5B variants naturally resistant to non-nucleoside, but not to nucleoside, polymerase inhibitors among untreated patients

    Existence of hepatitis C virus NS5B variants naturally resistant to non-nucleoside, but not to nucleoside, polymerase inhibitors among untreated patients Autor Sophie Le Pogam, A. Seshaadri, Alan Kosaka, Stephan Chiu, Hyunsoon Kang, Song Hu, Sonal Rajyaguru, Julian Symons, N. Cammack, Isabel Nájera

    Vydáno 2008
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  8. 8
    The Hepatitis C Virus Replicon Presents a Higher Barrier to Resistance to Nucleoside Analogs than to Nonnucleoside Polymerase or Protease Inhibitors

    The Hepatitis C Virus Replicon Presents a Higher Barrier to Resistance to Nucleoside Analogs than to Nonnucleoside Polymerase or Protease Inhibitors Autor Matthew F. McCown, Sonal Rajyaguru, Sophie Le Pogam, Samir Ali, Wen-Rong Jiang, Hyunsoon Kang, Julian Symons, Nick Cammack, Isabel Nájera

    Vydáno 2008
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  9. 9
    Combinations of Oseltamivir and T-705 Extend the Treatment Window for Highly Pathogenic Influenza A(H5N1) Virus Infection in Mice

    Combinations of Oseltamivir and T-705 Extend the Treatment Window for Highly Pathogenic Influenza A(H5N1) Virus Infection in Mice Autor Bindumadhav M. Marathe, Sook‐San Wong, Peter Vogel, Fernando García-Alcalde, Robert G. Webster, Richard J. Webby, Isabel Nájera, Elena A. Govorkova

    Vydáno 2016
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  10. 10
    A Novel Endonuclease Inhibitor Exhibits Broad-Spectrum Anti-Influenza Virus Activity <i>In Vitro</i>

    A Novel Endonuclease Inhibitor Exhibits Broad-Spectrum Anti-Influenza Virus Activity <i>In Vitro</i> Autor Jeremy C. Jones, Bindumadhav M. Marathe, C. Lerner, Lukas M. Kreis, Rodolfo Gasser, Philippe Noriel Q. Pascua, Isabel Nájera, Elena A. Govorkova

    Vydáno 2016
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  11. 11
    In Vivo Emergence of a Novel Mutant L159F/L320F in the NS5B Polymerase Confers Low-Level Resistance to the HCV Polymerase Inhibitors Mericitabine and Sofosbuvir

    In Vivo Emergence of a Novel Mutant L159F/L320F in the NS5B Polymerase Confers Low-Level Resistance to the HCV Polymerase Inhibitors Mericitabine and Sofosbuvir Autor Xiao Tong, Sophie Le Pogam, Lewyn Li, Kristin Haines, Katherine Piso, Victoria A. Baronas, Junmei Yan, Sung‐Sau So, Klaus Klumpp, Isabel Nájera

    Vydáno 2013
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  12. 12
    RG7128 Alone or in Combination with Pegylated Interferon‐α2a and Ribavirin Prevents Hepatitis C Virus (HCV) Replication and Selection of Resistant Variants in HCV‐Infected Patients

    RG7128 Alone or in Combination with Pegylated Interferon‐α2a and Ribavirin Prevents Hepatitis C Virus (HCV) Replication and Selection of Resistant Variants in HCV‐Infected Patients... Autor Sophie Le Pogam, A. Seshaadri, Aren Ewing, Hyunsoon Kang, Alan Kosaka, Junmei Yan, M. Michelle Berrey, B. Symonds, Abel De La Rosa, Nick Cammack, Isabel Nájera

    Vydáno 2010
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  13. 13
    Selected Replicon Variants with Low-Level In Vitro Resistance to the Hepatitis C Virus NS5B Polymerase Inhibitor PSI-6130 Lack Cross-Resistance with R1479

    Selected Replicon Variants with Low-Level In Vitro Resistance to the Hepatitis C Virus NS5B Polymerase Inhibitor PSI-6130 Lack Cross-Resistance with R1479 Autor Samir Ali, Vincent Lévêque, Sophie Le Pogam, Han Ma, Friederike Philipp, Nicole Inocencio, Mark Smith, André Alker, Hyunsoon Kang, Isabel Nájera, Klaus Klumpp, Julian Symons, Nick Cammack, Wen-Rong Jiang

    Vydáno 2008
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  14. 14
    R1626 plus peginterferon Alfa-2a provides potent suppression of hepatitis C virus RNA and significant antiviral synergy in combination with ribavirin

    R1626 plus peginterferon Alfa-2a provides potent suppression of hepatitis C virus RNA and significant antiviral synergy in combination with ribavirin Autor Paul J. Pockros, David R. Nelson, Eliot Godofsky, M. Rodríguez‐Torres, Gregory T. Everson, Michael Fried, Reem Ghalib, Stephen A. Harrison, Lisa M. Nyberg, Mitchell L. Shiffman, Isabel Nájera, Anna Chan, George Hill

    Vydáno 2008
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  15. 15
    Selection and Characterization of Replicon Variants Dually Resistant to Thumb- and Palm-Binding Nonnucleoside Polymerase Inhibitors of the Hepatitis C Virus

    Selection and Characterization of Replicon Variants Dually Resistant to Thumb- and Palm-Binding Nonnucleoside Polymerase Inhibitors of the Hepatitis C Virus Autor Sophie Le Pogam, Hyunsoon Kang, Seth F. Harris, Vincent Lévêque, Anthony M. Giannetti, Samir Ali, Wen-Rong Jiang, Sonal Rajyaguru, Gisele Tavares, Connie Oshiro, Than Hendricks, Klaus Klumpp, Julian Symons, Michelle F. Browner, Nick Cammack, Isabel Nájera

    Vydáno 2006
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  16. 16
    Slow Binding Inhibition and Mechanism of Resistance of Non-nucleoside Polymerase Inhibitors of Hepatitis C Virus

    Slow Binding Inhibition and Mechanism of Resistance of Non-nucleoside Polymerase Inhibitors of Hepatitis C Virus Autor Julie Q. Hang, Yanli Yang, Seth F. Harris, Vincent Lévêque, Hannah J. Whittington, Sonal Rajyaguru, Gloria Ao-Ieong, Matthew F. McCown, April Wong, Anthony M. Giannetti, Sophie Le Pogam, Francisco X. Talamás, Nick Cammack, Isabel Nájera, Klaus Klumpp

    Vydáno 2009
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  17. 17
    Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms

    Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms Autor Zheng Zhou, Taishan Hu, Xue Zhou, Steffen Wildum, Fernando García-Alcalde, Zhiheng Xu, Daitze Wu, Yi Mao, Xiao‐Jun Tian, Yuan Zhou, Fang Shen, Zhisen Zhang, Guozhi Tang, Isabel Nájera, Guang Yang, Hong C. Shen, John A. T. Young, Na Qin

    Vydáno 2017
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