Search Results - Isaac S. Chan

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  1. 1
    The changing role of natural killer cells in cancer metastasis

    The changing role of natural killer cells in cancer metastasis by Isaac S. Chan, Andrew J. Ewald

    Published 2022
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  2. 2
    Immunotherapy for Merkel cell carcinoma: a turning point in patient care

    Immunotherapy for Merkel cell carcinoma: a turning point in patient care by Isaac S. Chan, Shailender Bhatia, Howard L. Kaufman, Evan J. Lipson

    Published 2018
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  3. 3
    Antibody-drug conjugates in breast cancer: overcoming resistance and boosting immune response

    Antibody-drug conjugates in breast cancer: overcoming resistance and boosting immune response by Hannah L. Chang, Blake Schwettmann, Heather L. McArthur, Isaac S. Chan

    Published 2023
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  4. 4
    Hedgehog signalling regulates liver sinusoidal endothelial cell capillarisation

    Hedgehog signalling regulates liver sinusoidal endothelial cell capillarisation by Guanhua Xie, Steve S. Choi, Wing-Kin Syn, Gregory A. Michelotti, Marzena Swiderska, Gamze Karaca, Isaac S. Chan, Yuping Chen, Anna Mae Diehl

    Published 2012
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  5. 5
    Cancer cells educate natural killer cells to a metastasis-promoting cell state

    Cancer cells educate natural killer cells to a metastasis-promoting cell state by Isaac S. Chan, Hildur Knútsdóttir, Gayathri Ramakrishnan, Veena Padmanaban, Manisha Warrier, Juan Carlos Ramı́rez, Matthew Dunworth, Hao Zhang, Elizabeth M. Jaffee, Joel S. Bader, Andrew J. Ewald

    Published 2020
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  6. 6
    Hedgehog Controls Hepatic Stellate Cell Fate by Regulating Metabolism

    Hedgehog Controls Hepatic Stellate Cell Fate by Regulating Metabolism by Yuping Chen, Steve S. Choi, Gregory A. Michelotti, Isaac S. Chan, Marzena Swiderska‐Syn, Gamze Karaca, Guanhua Xie, Cynthia A. Moylan, Francesca Garibaldi, Richard T. Premont, Hagir B. Suliman, Claude A. Piantadosi, Anna Mae Diehl

    Published 2012
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  7. 7
    A comprehensive single-cell breast tumor atlas defines epithelial and immune heterogeneity and interactions predicting anti-PD-1 therapy response

    A comprehensive single-cell breast tumor atlas defines epithelial and immune heterogeneity and interactions predicting anti-PD-1 therapy response by Lily Xu, Kaitlyn Saunders, Shao-Po Huang, Hildur Knútsdóttir, Kenneth Martinez-Algarin, Isabella Terrazas, Kenian Chen, Heather M. McArthur, Julia Maués, Christine Hodgdon, Sangeetha M. Reddy, Evanthia T. Roussos Torres, Lin Xu, Isaac S. Chan

    Published 2024
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  8. 8
    Macrophage‐derived hedgehog ligands promotes fibrogenic and angiogenic responses in human schistosomiasis mansoni

    Macrophage‐derived hedgehog ligands promotes fibrogenic and angiogenic responses in human schistosomiasis mansoni by Thiago A. Pereira, Guanhua Xie, Steve S. Choi, Wing‐Kin Syn, Izabela Voieta, Jiuyi Lü, Isaac S. Chan, Marzena Swiderska, Kirsten Amaral, Carlos Antunes, W. Evan Secor, Rafal P. Witek, José Roberto Lambertucci, Fausto L. Pereira, Anna Mae Diehl

    Published 2012
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  9. 9
    Paracrine Hedgehog Signaling Drives Metabolic Changes in Hepatocellular Carcinoma

    Paracrine Hedgehog Signaling Drives Metabolic Changes in Hepatocellular Carcinoma by Isaac S. Chan, Cynthia D. Guy, Yuping Chen, Jiuyi Lü, Marzena Swiderska‐Syn, Gregory A. Michelotti, Gamze Karaca, Guanhua Xie, Leandi Krüger, Wing-Kin Syn, Blair R. Anderson, Thiago A. Pereira, Steve S. Choi, Albert S. Baldwin, Anna Mae Diehl

    Published 2012
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  10. 10
    Hedgehog Signaling Antagonist Promotes Regression of Both Liver Fibrosis and Hepatocellular Carcinoma in a Murine Model of Primary Liver Cancer

    Hedgehog Signaling Antagonist Promotes Regression of Both Liver Fibrosis and Hepatocellular Carcinoma in a Murine Model of Primary Liver Cancer by George Philips, Isaac S. Chan, Marzena Swiderska, Vanessa T. Schroder, Cynthia D. Guy, Gamze Karaca, Cynthia A. Moylan, Talaignair N. Venkatraman, Sebastian Feuerlein, Wing-Kin Syn, Youngmi Jung, Rafal P. Witek, Steve S. Choi, Gregory A. Michelotti, Fatima Rangwala, Elmar M. Merkle, Christopher D. Lascola, Anna Mae Diehl

    Published 2011
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  11. 11
    NKT-associated hedgehog and osteopontin drive fibrogenesis in non-alcoholic fatty liver disease

    NKT-associated hedgehog and osteopontin drive fibrogenesis in non-alcoholic fatty liver disease by Wing-Kin Syn, Kolade M. Agboola, Marzena Swiderska, Gregory A. Michelotti, Evaggelia Liaskou, Herbert Pang, Guanhua Xie, George Philips, Isaac S. Chan, Gamze Karaca, Thiago A. Pereira, Yuping Chen, Zhiyong Mi, Paul C. Kuo, Steve S. Choi, Cynthia D. Guy, Manal F. Abdelmalek, Anna Mae Diehl

    Published 2012
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  12. 12
    Schistosome-induced cholangiocyte proliferation and osteopontin secretion correlate with fibrosis and portal hypertension in human and murine schistosomiasis mansoni

    Schistosome-induced cholangiocyte proliferation and osteopontin secretion correlate with fibrosis and portal hypertension in human and murine schistosomiasis mansoni by Thiago A. Pereira, Wing‐Kin Syn, Mariana Verdelho Machado, Paula Vieira Teixeira Vidigal, Vívian Resende, Izabela Voieta, Guanhua Xie, Alba Otoni, Márcia María de Souza, Elisângela Trindade Santos, Isaac S. Chan, Elisângela Trindade Santos, Steve S. Choi, Rafal P. Witek, Fausto Edmundo Lima Pereira, W. Evan Secor, Zilton A. Andrade, José Roberto Lambertucci, Anna Mae Diehl

    Published 2015
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  13. 13
    An expanded universe of cancer targets

    An expanded universe of cancer targets by William C. Hahn, Joel S. Bader, Theodore P. Braun, Andrea Califano, Paul A. Clemons, Brian J. Druker, Andrew J. Ewald, Haian Fu, Subhashini Jagu, Christopher J. Kemp, William Kim, Calvin J. Kuo, Michael T. McManus, Gordon B. Mills, Xiulei Mo, Nidhi Sahni, Stuart L. Schreiber, Jessica A. Talamas, Pablo Tamayo, Jeffrey W. Tyner, Bridget K. Wagner, William A. Weiss, Daniela S. Gerhard, Vlado Dančík, Shubhroz Gill, Bruce K. Hua, Tanaz Sharifnia, Vasanthi S. Viswanathan, Yilong Zou, Filemon S. Dela Cruz, Andrew L. Kung, Brent R. Stockwell, Jesse S. Boehm, Josh Dempster, Robert T. Manguso, Francisca Vázquez, Lee Cooper, Yuhong Du, Andrei A. Ivanov, Sagar Lonial, Carlos S. Moreno, Qiankun Niu, Taofeek K. Owonikoko, Suresh S. Ramalingam, Matthew A. Reyna, Wei Zhou, Carla Grandori, Ilya Shmulevich, Elizabeth M. Swisher, Jitong Cai, Isaac S. Chan, Matthew Dunworth, Yuchen Ge, Dan Georgess, Eloïse M. Grasset, Elodie Henriet, Hildur Knútsdóttir, Michael G. Lerner, Veena Padmanaban, Matthew C. Perrone, Yasir Suhail, Yohannes Tsehay, Manisha Warrier, Quin Morrow, Tamilla Nechiporuk, Nicola Long, Jennifer N. Saultz, Andy Kaempf, Jessica Minnier, Cristina E. Tognon, Stephen E. Kurtz, Anupriya Agarwal, Jordana F. Brown, Kevin Watanabe‐Smith, Tania Q. Vu, Thomas Jacob, Yunqi Yan, Bridget A. Robinson, Evan Lind, Yoko Kosaka, Emek Demir, Joseph Estabrook, Michael Grzadkowski, Olga Nikolova, Ken Chen, Ben Deneen, Han Liang, Michael C. Bassik, Asmita Bhattacharya, Kevin Brennan, Christina Curtis, Olivier Gevaert, Hanlee P. Ji, Kasper Karlsson, Kremena Karagyozova, Yuan‐Hung Lo, Katherine Liu, Michitaka Nakano, Anuja Sathe, Amber R. Smith

    Published 2021
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