Výsledky vyhledávání - Ioannis Assiotis

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  1. 1
    Genome-wide functional screen identifies a compendium of genes affecting sensitivity to tamoxifen

    Genome-wide functional screen identifies a compendium of genes affecting sensitivity to tamoxifen Autor Ana M. Mendes‐Pereira, David Sims, Tim Dexter, Kerry Fenwick, Ioannis Assiotis, Iwanka Kozarewa, Costas Mitsopoulos, Jarle Hakas, Marketa Zvelebil, Christopher J. Lord, Alan Ashworth

    Vydáno 2011
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  2. 2
    A Genetic Screen Using the PiggyBac Transposon in Haploid Cells Identifies Parp1 as a Mediator of Olaparib Toxicity

    A Genetic Screen Using the PiggyBac Transposon in Haploid Cells Identifies Parp1 as a Mediator of Olaparib Toxicity Autor Stephen J. Pettitt, Farah Rehman, Ilirjana Bajrami, Rachel Brough, Fredrik Wållberg, Iwanka Kozarewa, Kerry Fenwick, Ioannis Assiotis, Lina Chen, James Campbell, Christopher J. Lord, Alan Ashworth

    Vydáno 2013
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  3. 3
    Genome-wide analysis of p63 binding sites identifies AP-2 factors as co-regulators of epidermal differentiation

    Genome-wide analysis of p63 binding sites identifies AP-2 factors as co-regulators of epidermal differentiation Autor Simon S. McDade, Alexandra E. Henry, Géraldine Pivato, Iwanka Kozarewa, Costas Mitsopoulos, Kerry Fenwick, Ioannis Assiotis, Jarle Hakas, Marketa Zvelebil, Nick Orr, Christopher J. Lord, D. Patel, Alan Ashworth, Dennis J. McCance

    Vydáno 2012
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  4. 4
    Genome-wide Profiling of Genetic Synthetic Lethality Identifies CDK12 as a Novel Determinant of PARP1/2 Inhibitor Sensitivity

    Genome-wide Profiling of Genetic Synthetic Lethality Identifies CDK12 as a Novel Determinant of PARP1/2 Inhibitor Sensitivity Autor Ilirjana Bajrami, Jessica Frankum, Asha Konde, Rowan Miller, Farah Rehman, Rachel Brough, James Campbell, David Sims, Rumana Rafiq, Sean Hooper, Lina Chen, Iwanka Kozarewa, Ioannis Assiotis, Kerry Fenwick, Rachael Natrajan, Christopher J. Lord, Alan Ashworth

    Vydáno 2013
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  5. 5
    High-throughput RNA interference screening using pooled shRNA libraries and next generation sequencing

    High-throughput RNA interference screening using pooled shRNA libraries and next generation sequencing Autor David Sims, Ana M. Mendes‐Pereira, Jessica Frankum, Darren J. Burgess, Maria-Antonietta Cerone, C. Lombardelli, Costas Mitsopoulos, Jarle Hakas, Nirupa Murugaesu, Clare M. Isacke, Kerry Fenwick, Ioannis Assiotis, Iwanka Kozarewa, Marketa Zvelebil, Alan Ashworth, Christopher J. Lord

    Vydáno 2011
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  6. 6
    Frequent germline deleterious mutations in DNA repair genes in familial prostate cancer cases are associated with advanced disease

    Frequent germline deleterious mutations in DNA repair genes in familial prostate cancer cases are associated with advanced disease Autor Daniel Leongamornlert, Edward J. Saunders, Tokhir Dadaev, Malgorzata Tymrakiewicz, Chee Goh, Sarah Jugurnauth-Little, Iwanka Kozarewa, Kerry Fenwick, Ioannis Assiotis, Daniel Barrowdale, Koveela Govindasami, Michelle Guy, Emma Sawyer, Rosemary Wilkinson, Antonis C. Antoniou, Rosalind A. Eeles, Zsofia Kote‐Jarai

    Vydáno 2014
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  7. 7
    Capture Hi-C identifies putative target genes at 33 breast cancer risk loci

    Capture Hi-C identifies putative target genes at 33 breast cancer risk loci Autor Joseph S. Baxter, Olivia C. Leavy, Nicola H. Dryden, Sarah Maguire, Nichola Johnson, Vita Fedele, Nikiana Simigdala, Lesley‐Ann Martin, Simon Andrews, Steven W. Wingett, Ioannis Assiotis, Kerry Fenwick, Ritika Chauhan, Alistair G. Rust, Nick Orr, Frank Dudbridge, Syed Haider, Olivia Fletcher

    Vydáno 2018
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  8. 8
    Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C

    Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C Autor Nicola H. Dryden, Laura R. Broome, Frank Dudbridge, Nichola Johnson, Nick Orr, Stefan Schoenfelder, Takashi Nagano, Simon Andrews, Steven W. Wingett, Iwanka Kozarewa, Ioannis Assiotis, Kerry Fenwick, Sarah Maguire, James Campbell, Rachael Natrajan, Maryou Lambros, Eleni Perrakis, Alan Ashworth, Peter Fraser, Olivia Fletcher

    Vydáno 2014
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  9. 9
    Poly (ADP-ribose) polymerase (PARP) inhibitors for the treatment of advanced germline BRCA2 mutant prostate cancer

    Poly (ADP-ribose) polymerase (PARP) inhibitors for the treatment of advanced germline BRCA2 mutant prostate cancer Autor Shahneen Sandhu, Aurelius Omlin, Lucy Hylands, Susana Miranda, Louise J. Barber, Ruth Riisnaes, Alison Reid, Gerhardt Attard, L. Chen, Iwanka Kozarewa, Heidi Gevensleben, James Campbell, Kerry Fenwick, Ioannis Assiotis, David Olmos, Timothy A. Yap, Peter C.C. Fong, Nina Tunariu, Dow‐Mu Koh, L. Rhoda Molife, S.B. Kaye, Christopher J. Lord, Alan Ashworth, Johann S. de Bono

    Vydáno 2013
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  10. 10
    Efficacy of Chemotherapy in <i>BRCA1/2</i> Mutation Carrier Ovarian Cancer in the Setting of PARP Inhibitor Resistance: A Multi-Institutional Study

    Efficacy of Chemotherapy in <i>BRCA1/2</i> Mutation Carrier Ovarian Cancer in the Setting of PARP Inhibitor Resistance: A Multi-Institutional Study Autor Joo Ern Ang, Charlie Gourley, C. Bethan Powell, Hilda High, Ronnie Shapira‐Frommer, Vincent Castonguay, Jacques De Grève, Tina Atkinson, Timothy A. Yap, Shahneen Sandhu, Susana Banerjee, Lee-may Chen, Michael Friedlander, Bella Kaufman, Amit M. Oza, Ursula A. Matulonis, Louise J. Barber, Iwanka Kozarewa, Kerry Fenwick, Ioannis Assiotis, James Campbell, Lina Chen, Johann S. de Bono, Martin Gore, Christopher J. Lord, Alan Ashworth, Stan B. Kaye

    Vydáno 2013
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  11. 11
    Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor

    Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor Autor Kevin Litchfield, Max Levy, Giulia Orlando, Chey Loveday, Philip Law, Gabriele Migliorini, Amy Holroyd, Peter Broderick, Robert Karlsson, Trine B. Haugen, Wenche Kristiansen, Jérémie Nsengimana, Kerry Fenwick, Ioannis Assiotis, Zsofia Kote‐Jarai, Alison M. Dunning, Kenneth Muir, Julian Peto, Rosalind A. Eeles, Douglas F. Easton, Darshna Dudakia, Nick Orr, Nora Pashayan, D. Timothy Bishop, Alison Reid, Robert Huddart, Janet Shipley, Tom Grotmol, Fredrik Wiklund, Richard S. Houlston, Clare Turnbull

    Vydáno 2017
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