Search Results - Ina Oehme

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  1. 1
    HDAC Family Members Intertwined in the Regulation of Autophagy: A Druggable Vulnerability in Aggressive Tumor Entities

    HDAC Family Members Intertwined in the Regulation of Autophagy: A Druggable Vulnerability in Aggressive Tumor Entities by E Koeneke, Olaf Witt, Ina Oehme

    Published 2015
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  2. 2
    The enzyme activity of histone deacetylase 8 is modulated by a redox-switch

    The enzyme activity of histone deacetylase 8 is modulated by a redox-switch by Niklas Jänsch, Christian Meyners, Marius Muth, Aleksandra Kopranovic, Olaf Witt, Ina Oehme, Franz‐Josef Meyer‐Almes

    Published 2018
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  3. 3
    HDAC8: a multifaceted target for therapeutic interventions

    HDAC8: a multifaceted target for therapeutic interventions by Alokta Chakrabarti, Ina Oehme, Olaf Witt, Guilherme Oliveira, Wolfgang Sippl, Christophe Romier, Raymond J. Pierce, Manfred Jung

    Published 2015
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  4. 4
    Targeting Histone Deacetylase 8 as a Therapeutic Approach to Cancer and Neurodegenerative Diseases

    Targeting Histone Deacetylase 8 as a Therapeutic Approach to Cancer and Neurodegenerative Diseases by Alokta Chakrabarti, Jelena Melesina, Fiona R. Kolbinger, Ina Oehme, Johanna Senger, Olaf Witt, Wolfgang Sippl, Manfred Jung

    Published 2016
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  5. 5
    Downregulation of the activating NKp30 ligand B7-H6 by HDAC inhibitors impairs tumor cell recognition by NK cells

    Downregulation of the activating NKp30 ligand B7-H6 by HDAC inhibitors impairs tumor cell recognition by NK cells by Nathalie Fiegler, Sonja Textor, Annette Arnold, Alexander Rölle, Ina Oehme, Kai Breuhahn, Gerhard Moldenhauer, Mathias Witzens‐Harig, Adelheid Cerwenka

    Published 2013
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  6. 6
    Combination drug screen identifies synergistic drug interaction of BCL-XL and class I histone deacetylase inhibitors in MYC-amplified medulloblastoma cells

    Combination drug screen identifies synergistic drug interaction of BCL-XL and class I histone deacetylase inhibitors in MYC-amplified medulloblastoma cells by Simon Zeuner, Johanna Vollmer, Romain Sigaud, Sina Oppermann, Heike Peterziel, Dina ElHarouni, Ina Oehme, Olaf Witt, Till Milde, Jonas Ecker

    Published 2024
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  7. 7
    Histone Deacetylase 8 in Neuroblastoma Tumorigenesis

    Histone Deacetylase 8 in Neuroblastoma Tumorigenesis by Ina Oehme, Hedwig E. Deubzer, Dennis Wegener, Diana Pickert, Jan-Peter Linke, Barbara Hero, Annette Kopp‐Schneider, Frank Westermann, Scott Ulrich, Andreas von Deimling, Matthias Fischer, Olaf Witt

    Published 2008
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  8. 8
    Selective Inhibition of Histone Deacetylase 10: Hydrogen Bonding to the Gatekeeper Residue is Implicated

    Selective Inhibition of Histone Deacetylase 10: Hydrogen Bonding to the Gatekeeper Residue is Implicated by Magalie Géraldy, Michael Morgen, Peter Sehr, Raphael R. Steimbach, Davide Moi, Johannes Ridinger, Ina Oehme, Olaf Witt, Mona Malz, Mauro S. Nogueira, Oliver Koch, Nikolas Gunkel, Aubry K. Miller

    Published 2019
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  9. 9
    Three-dimensional tumor cell growth stimulates autophagic flux and recapitulates chemotherapy resistance

    Three-dimensional tumor cell growth stimulates autophagic flux and recapitulates chemotherapy resistance by Corinna Bingel, E Koeneke, Johannes Ridinger, Annika Bittmann, Martin Sill, Heike Peterziel, Jagoda K. Wrobel, I Rettig, Till Milde, Uta Fernekorn, Frank Weise, Andreas Schober, Olaf Witt, Ina Oehme

    Published 2017
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  10. 10
    Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance

    Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance by Johannes Ridinger, E Koeneke, Fiona R. Kolbinger, Katharina Koerholz, Siavosh Mahboobi, Lars Hellweg, Nikolas Gunkel, Aubry K. Miller, Heike Peterziel, Peter Schmezer, Anne Hamacher‐Brady, Olaf Witt, Ina Oehme

    Published 2018
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  11. 11
    Selective degradation of mutant FMS-like tyrosine kinase-3 requires BIM-dependent depletion of heat shock proteins

    Selective degradation of mutant FMS-like tyrosine kinase-3 requires BIM-dependent depletion of heat shock proteins by Melisa Halilovic, Mohamed Abdelsalam, Joanna Zabkiewicz, Michelle Lazenby, Caroline Alvares, Matthias Schmidt, Walburgis Brenner, Sara Najafi, Ina Oehme, Christoph Hieber, Yanira Zeyn, Matthias Bros, Wolfgang Sippl, Oliver H. Krämer

    Published 2024
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  12. 12
    HDAC5 and HDAC9 in Medulloblastoma: Novel Markers for Risk Stratification and Role in Tumor Cell Growth

    HDAC5 and HDAC9 in Medulloblastoma: Novel Markers for Risk Stratification and Role in Tumor Cell Growth by Till Milde, Ina Oehme, Andrey Korshunov, Annette Kopp‐Schneider, Marc Remke, Paul A. Northcott, Hedwig E. Deubzer, Marco Lodrini, Michael D. Taylor, Andreas von Deimling, Stefan M. Pfister, Olaf Witt

    Published 2010
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  13. 13
    Selective inhibition of HDAC8 decreases neuroblastoma growth in vitro and in vivo and enhances retinoic acid-mediated differentiation

    Selective inhibition of HDAC8 decreases neuroblastoma growth in vitro and in vivo and enhances retinoic acid-mediated differentiation by I Rettig, E Koeneke, Franziska Trippel, Wolf Mueller, Jürgen Burhenne, Annette Kopp‐Schneider, Johannes Fabian, Andreas Schober, Uta Fernekorn, Andreas von Deimling, Hedwig E. Deubzer, Till Milde, Olaf Witt, Ina Oehme

    Published 2015
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  14. 14
    Design, Synthesis and Biological Characterization of Histone Deacetylase 8 (HDAC8) Proteolysis Targeting Chimeras (PROTACs) with Anti-Neuroblastoma Activity

    Design, Synthesis and Biological Characterization of Histone Deacetylase 8 (HDAC8) Proteolysis Targeting Chimeras (PROTACs) with Anti-Neuroblastoma Activity by Salma Darwish, Ehab Ghazy, Tino Heimburg, Daniel Herp, Patrik Zeyen, Rabia Salem-Altintas, Johannes Ridinger, Dina Robaa, Matthias Schmidt, Frank Erdmann, Matthias Schmidt, Christophe Romier, Manfred Jung, Ina Oehme, Wolfgang Sippl

    Published 2022
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  15. 15
    Reactivation of endogenous retroviral elements via treatment with DNMT- and HDAC-inhibitors

    Reactivation of endogenous retroviral elements via treatment with DNMT- and HDAC-inhibitors by Michael Daskalakis, David Brocks, Yi-Hua Sheng, Md. Saiful Islam, Alzbeta Ressnerova, Yassen Assenov, Till Milde, Ina Oehme, Olaf Witt, Ashish Goyal, Alexander Kühn, Mark Hartmann, Dieter Weichenhan, Manfred Jung, Christoph Plass

    Published 2018
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  16. 16
    Nestin Expression Identifies Ependymoma Patients with Poor Outcome

    Nestin Expression Identifies Ependymoma Patients with Poor Outcome by Till Milde, Thomas Hielscher, Hendrik Witt, Marcel Kool, Stephen C. Mack, Hedwig E. Deubzer, Ina Oehme, Marco Lodrini, Axel Benner, Michael D. Taylor, Andreas von Deimling, Andreas E. Kulozik, Stefan M. Pfister, Olaf Witt, Andrey Korshunov

    Published 2012
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  17. 17
    Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma

    Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma by Jonas Ecker, Ina Oehme, Ralph Mazitschek, Andrey Korshunov, Marcel Kool, Thomas Hielscher, Judit Kiss, Florian Selt, Carina Konrad, Marco Lodrini, Hedwig E. Deubzer, Andreas von Deimling, Andreas E. Kulozik, Stefan M. Pfister, Olaf Witt, Till Milde

    Published 2015
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  18. 18
    Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cells

    Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cells by Patrik Zeyen, Yanira Zeyn, Daniel Herp, Fereshteh Mahmoudi, Talha Z. Yesiloglu, Frank Erdmann, Matthias Schmidt, Dina Robaa, Christophe Romier, Johannes Ridinger, Corey J. Herbst‐Gervasoni, D.W. Christianson, Ina Oehme, Manfred Jung, Oliver H. Krämer, Wolfgang Sippl

    Published 2022
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  19. 19
    Genomic and phenotypic stability of fusion-driven pediatric sarcoma cell lines

    Genomic and phenotypic stability of fusion-driven pediatric sarcoma cell lines by Merve Kasan, Florian H. Geyer, Jana Siebenlist, Martin Sill, Rupert Öllinger, Tobias Faehling, Enrique de Álava, Didier Surdez, Uta Dirksen, Ina Oehme, Katia Scotlandi, Olivier Delattre, Martina Müller‐Nurasyid, Roland Rad, Konstantin Strauch, T. Grünewald, Florencia Cidre‐Aranaz

    Published 2025
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  20. 20
    MYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma

    MYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma by Marco Lodrini, Ina Oehme, Christina I. Schroeder, Till Milde, Marie C. Schier, Annette Kopp‐Schneider, Johannes H. Schulte, Matthias Fischer, Katleen De Preter, Filip Pattyn, M. Castoldi, Martina U. Muckenthaler, Andreas E. Kulozik, Frank Westermann, Olaf Witt, Hedwig E. Deubzer

    Published 2013
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