Search Results - Immanuel Purushothaman

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  1. 1
    Neuropathic pain promotes adaptive changes in gene expression in brain networks involved in stress and depression

    Neuropathic pain promotes adaptive changes in gene expression in brain networks involved in stress and depression by Giannina Descalzi, Vasiliki Mitsi, Immanuel Purushothaman, Sevasti Gaspari, Kleopatra Avrampou, Yong‐Hwee Eddie Loh, Li Shen, Venetia Zachariou

    Published 2017
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  2. 2
    Ketamine and Imipramine Reverse Transcriptional Signatures of Susceptibility and Induce Resilience-Specific Gene Expression Profiles

    Ketamine and Imipramine Reverse Transcriptional Signatures of Susceptibility and Induce Resilience-Specific Gene Expression Profiles by Rosemary C. Bagot, Hannah M. Cates, Immanuel Purushothaman, Vincent Vialou, Elizabeth A. Heller, Lynn Yieh, Benoît Labonté, Catherine J. Peña, Li Shen, Gayle Wittenberg, Eric J. Nestler

    Published 2016
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  3. 3
    Adolescent exposure to Δ9-tetrahydrocannabinol alters the transcriptional trajectory and dendritic architecture of prefrontal pyramidal neurons

    Adolescent exposure to Δ9-tetrahydrocannabinol alters the transcriptional trajectory and dendritic architecture of prefrontal pyramidal neurons by M. L. Miller, Benjamin Chadwick, Dara L. Dickstein, Immanuel Purushothaman, Gábor Egervári, Tanni Rahman, Chloé Tessereau, Patrick R. Hof, Panos Roussos, Li Shen, Mark G. Baxter, Yasmin L. Hurd

    Published 2018
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  4. 4
    In vivo imaging identifies temporal signature of D1 and D2 medium spiny neurons in cocaine reward

    In vivo imaging identifies temporal signature of D1 and D2 medium spiny neurons in cocaine reward by Erin S. Calipari, Rosemary C. Bagot, Immanuel Purushothaman, Thomas J. Davidson, Jordan T. Yorgason, Catherine J. Peña, Deena M. Walker, Stephen T. Pirpinias, Kevin G. Guise, Charu Ramakrishnan, Karl Deisseroth, Eric J. Nestler

    Published 2016
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  5. 5
    Early life stress alters transcriptomic patterning across reward circuitry in male and female mice

    Early life stress alters transcriptomic patterning across reward circuitry in male and female mice by Catherine J. Peña, Milo R. Smith, Aarthi Ramakrishnan, Hannah M. Cates, Rosemary C. Bagot, Hope Kronman, Bhakti Patel, Austin Chang, Immanuel Purushothaman, Joel T. Dudley, Hirofumi Morishita, Li Shen, Eric J. Nestler

    Published 2019
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  6. 6
    Tet1 in Nucleus Accumbens Opposes Depression- and Anxiety-Like Behaviors

    Tet1 in Nucleus Accumbens Opposes Depression- and Anxiety-Like Behaviors by Jian Feng, Catherine J. Peña, Immanuel Purushothaman, Olivia Engmann, Deena M. Walker, Amber N. Brown, Orna Issler, Marie A. Doyle, Eileen Harrigan, Ezekiell Mouzon, Vincent Vialou, Li Shen, Meelad M. Dawlaty, Rudolf Jaenisch, Eric J. Nestler

    Published 2017
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  7. 7
    Early life stress confers lifelong stress susceptibility in mice via ventral tegmental area OTX2

    Early life stress confers lifelong stress susceptibility in mice via ventral tegmental area OTX2 by Catherine J. Peña, Hope Kronman, Deena M. Walker, Hannah M. Cates, Rosemary C. Bagot, Immanuel Purushothaman, Orna Issler, Yong‐Hwee Eddie Loh, Tin Leong, Drew D. Kiraly, Emma Goodman, Rachael L. Neve, Li Shen, Eric J. Nestler

    Published 2017
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  8. 8
    Chronic cocaine-regulated epigenomic changes in mouse nucleus accumbens

    Chronic cocaine-regulated epigenomic changes in mouse nucleus accumbens by Jian Feng, Matthew B. Wilkinson, Xiaochuan Liu, Immanuel Purushothaman, Deveroux Ferguson, Vincent Vialou, Ian Maze, Ning‐Yi Shao, Pamela Kennedy, JaWook Koo, Caroline Dias, Benjamin M. Laitman, Victoria Stockman, Quincey LaPlant, Michael E. Cahill, Eric J. Nestler, Li Shen

    Published 2014
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  9. 9
    Epigenetic regulation of brain region-specific microglia clearance activity

    Epigenetic regulation of brain region-specific microglia clearance activity by Pinar Ayata, Ana Badimon, Hayley J. Strasburger, Mary Kaye Duff, Sarah Montgomery, Yong‐Hwee Eddie Loh, Anja Ebert, Anna A. Pimenova, Brianna R. Ramirez, Andrew Chan, Josefa M. Sullivan, Immanuel Purushothaman, Joseph R. Scarpa, Alison Goate, Meinrad Busslinger, Li Shen, Bojan Losic, Anne Schaefer

    Published 2018
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  10. 10
    Multidimensional Predictors of Susceptibility and Resilience to Social Defeat Stress

    Multidimensional Predictors of Susceptibility and Resilience to Social Defeat Stress by Carla Nasca, Caroline Ménard, Georgia E. Hodes, Benedetta Bigio, Catherine J. Peña, Zachary S. Lorsch, Danielle Zelli, Anjali Ferris, Veronika Kana, Immanuel Purushothaman, Josh Dobbin, Marouane Nassim, Paolo De Angelis, Miriam Mérad, Natalie Rasgon, Michael J. Meaney, Eric J. Nestler, Bruce S. McEwen, Scott J. Russo

    Published 2019
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  11. 11
    Sex Differences in Nucleus Accumbens Transcriptome Profiles Associated with Susceptibility versus Resilience to Subchronic Variable Stress

    Sex Differences in Nucleus Accumbens Transcriptome Profiles Associated with Susceptibility versus Resilience to Subchronic Variable Stress by Georgia E. Hodes, Madeline L. Pfau, Immanuel Purushothaman, Hongryul Ahn, Sam A. Golden, Daniel J. Christoffel, Jane Magida, Anna Brancato, Aki Takahashi, Meghan E. Flanigan, Caroline Ménard, Hossein Aleyasin, Ja Wook Koo, Zachary S. Lorsch, Jian Feng, Mitra Heshmati, Minghui Wang, Gustavo Turecki, Rachel L. Neve, Bin Zhang, Li Shen, Eric J. Nestler, Scott J. Russo

    Published 2015
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  12. 12
    Cocaine Self-administration Alters Transcriptome-wide Responses in the Brain’s Reward Circuitry

    Cocaine Self-administration Alters Transcriptome-wide Responses in the Brain’s Reward Circuitry by Deena M. Walker, Hannah M. Cates, Yong‐Hwee Eddie Loh, Immanuel Purushothaman, Aarthi Ramakrishnan, Kelly Cahill, Casey K. Lardner, Arthur Godino, Hope Kronman, Jacqui Rabkin, Zachary S. Lorsch, Philipp Mews, Marie A. Doyle, Jian Feng, Benoît Labonté, Ja Wook Koo, Rosemary C. Bagot, Ryan W. Logan, Marianne L. Seney, Erin S. Calipari, Li Shen, Eric J. Nestler

    Published 2018
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  13. 13
    Transcriptional and physiological adaptations in nucleus accumbens somatostatin interneurons that regulate behavioral responses to cocaine

    Transcriptional and physiological adaptations in nucleus accumbens somatostatin interneurons that regulate behavioral responses to cocaine by Efrain Ribeiro, Marine Salery, Joseph R. Scarpa, Erin S. Calipari, Peter J. Hamilton, Stacy M. Ku, Hope Kronman, Immanuel Purushothaman, Barbara Juarez, Mitra Heshmati, Marie A. Doyle, Casey K. Lardner, Dominicka Burek, Ana N. Strat, Stephen T. Pirpinias, Ezekiell Mouzon, Ming‐Hu Han, Rachael L. Neve, Rosemary C. Bagot, Andrew Kasarskis, Ja Wook Koo, Eric J. Nestler

    Published 2018
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  14. 14
    Estrogen receptor α drives pro-resilient transcription in mouse models of depression

    Estrogen receptor α drives pro-resilient transcription in mouse models of depression by Zachary S. Lorsch, Yong-Hwee Eddie Loh, Immanuel Purushothaman, Deena M. Walker, Eric M. Parise, Marine Salery, Michael E. Cahill, Georgia E. Hodes, Madeline L. Pfau, Hope Kronman, Peter J. Hamilton, Orna Issler, Benoît Labonté, Ann E. Symonds, Matthew Zucker, Tie Yuan Zhang, Michael J. Meaney, Scott J. Russo, Li Shen, Rosemary C. Bagot, Eric J. Nestler

    Published 2018
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  15. 15
    Critical Role of Histone Turnover in Neuronal Transcription and Plasticity

    Critical Role of Histone Turnover in Neuronal Transcription and Plasticity by Ian Maze, Wendy Wenderski, Kyung‐Min Noh, Rosemary C. Bagot, Nikos Tzavaras, Immanuel Purushothaman, Simon J. Elsässer, Yin Guo, Carolina Ionete, Yasmin L. Hurd, Carol A. Tamminga, Tobias Halene, Lorna A. Farrelly, Alexey A. Soshnev, Duancheng Wen, Shahin Rafii, Marc R. Birtwistle, Schahram Akbarian, Bruce A. Buchholz, Robert D. Blitzer, Eric J. Nestler, Zuo‐Fei Yuan, Benjamin A. Garcia, Li Shen, Henrik Molina, C. David Allis

    Published 2015
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  16. 16
    Circuit-wide Transcriptional Profiling Reveals Brain Region-Specific Gene Networks Regulating Depression Susceptibility

    Circuit-wide Transcriptional Profiling Reveals Brain Region-Specific Gene Networks Regulating Depression Susceptibility by Rosemary C. Bagot, Hannah M. Cates, Immanuel Purushothaman, Zachary S. Lorsch, Deena M. Walker, Junshi Wang, Xiaojie Huang, Oliver M. Schlüter, Ian Maze, Catherine J. Peña, Elizabeth A. Heller, Orna Issler, Minghui Wang, Won-Min Song, Jason L. Stein, Xiaochuan Liu, Marie A. Doyle, Kimberly N. Scobie, HaoSheng Sun, Rachael L. Neve, Daniel H. Geschwind, Yan Dong, Li Shen, Bin Zhang, Eric J. Nestler

    Published 2016
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  17. 17
    Sex-Specific Role for the Long Non-coding RNA LINC00473 in Depression

    Sex-Specific Role for the Long Non-coding RNA LINC00473 in Depression by Orna Issler, Yentl Y. van der Zee, Aarthi Ramakrishnan, Junshi Wang, Chunfeng Tan, Yong‐Hwee Eddie Loh, Immanuel Purushothaman, Deena M. Walker, Zachary S. Lorsch, Peter J. Hamilton, Catherine J. Peña, Erin Flaherty, Brigham J. Hartley, Angélica Torres‐Berrío, Eric M. Parise, Hope Kronman, Julia E. Duffy, Molly Estill, Erin S. Calipari, Benoît Labonté, Rachael L. Neve, Carol A. Tamminga, Kristen Brennand, Yan Dong, Li Shen, Eric J. Nestler

    Published 2020
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  18. 18
    Sex-specific transcriptional signatures in human depression

    Sex-specific transcriptional signatures in human depression by Benoît Labonté, Olivia Engmann, Immanuel Purushothaman, Caroline Ménard, Junshi Wang, Chunfeng Tan, Joseph R. Scarpa, Gregory Moy, Yong‐Hwee Eddie Loh, Michael E. Cahill, Zachary S. Lorsch, Peter J. Hamilton, Erin S. Calipari, Georgia E. Hodes, Orna Issler, Hope Kronman, Madeline L. Pfau, Aleksandar Lj. Obradović, Yan Dong, Rachael L. Neve, Scott J. Russo, Andrew Kasarskis, Carol A. Tamminga, Naguib Mechawar, Gustavo Turecki, Bin Zhang, Li Shen, Eric J. Nestler

    Published 2017
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