Resultats de la cerca - Hussein Al‐Mossawi

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  1. 1
    Progress in our understanding of the pathogenesis of ankylosing spondylitis

    Progress in our understanding of the pathogenesis of ankylosing spondylitis per Davide Simone, Mohammed Hussein Al Mossawi, Paul Bowness

    Publicat 2018
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  2. 2
    Novel Therapeutic Targets in Axial Spondyloarthritis

    Novel Therapeutic Targets in Axial Spondyloarthritis per Worth, Claudia, Bowness, Paul, Hussein Al-Mossawi, M.

    Publicat 2018
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  3. 3
    Single cell analysis of spondyloarthritis regulatory T cells identifies distinct synovial gene expression patterns and clonal fates

    Single cell analysis of spondyloarthritis regulatory T cells identifies distinct synovial gene expression patterns and clonal fates per Davide Simone, Frank Penkava, Anna Ridley, Stephen N. Sansom, Hussein Al‐Mossawi, Paul Bowness

    Publicat 2021
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  4. 4
    Silencing or inhibition of endoplasmic reticulum aminopeptidase 1 (ERAP1) suppresses free heavy chain expression and Th17 responses in ankylosing spondylitis

    Silencing or inhibition of endoplasmic reticulum aminopeptidase 1 (ERAP1) suppresses free heavy chain expression and Th17 responses in ankylosing spondylitis per Liye Chen, Anna Ridley, Ariane Hammitzsch, Hussein Al‐Mossawi, Helen Bunting, Dimitris Georgiadis, Antoni Chan, Simon Kollnberger, Paul Bowness

    Publicat 2015
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  5. 5
    Persistent stromal fibroblast activation is present in chronic tendinopathy

    Persistent stromal fibroblast activation is present in chronic tendinopathy per Stephanie G. Dakin, Christopher D. Buckley, Hussein Al‐Mossawi, Robert Hedley, Fernando O. Martínez, Kim Wheway, Bridget Watkins, Andrew Carr

    Publicat 2017
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  6. 6
    Inhibiting ex-vivo Th17 responses in Ankylosing Spondylitis by targeting Janus kinases

    Inhibiting ex-vivo Th17 responses in Ankylosing Spondylitis by targeting Janus kinases per Ariane Hammitzsch, Liye Chen, Jelle de Wit, Hussein Al‐Mossawi, Anna Ridley, Takuya Sekine, Davide Simone, Karen Doig, Alla Skapenko, Paul Bowness

    Publicat 2018
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  7. 7
    Multi-omic single cell analysis resolves novel stromal cell populations in healthy and diseased human tendon

    Multi-omic single cell analysis resolves novel stromal cell populations in healthy and diseased human tendon per Adrian Kendal, T. B. Layton, Hussein Al‐Mossawi, Louise Appleton, Stephanie G. Dakin, Rick Brown, Constantinos Loizou, Mark Rogers, Robert Sharp, Andrew Carr

    Publicat 2020
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  8. 8
    Activation‐Induced Killer Cell Immunoglobulin‐like Receptor 3DL2 Binding to HLA–B27 Licenses Pathogenic T Cell Differentiation in Spondyloarthritis

    Activation‐Induced Killer Cell Immunoglobulin‐like Receptor 3DL2 Binding to HLA–B27 Licenses Pathogenic T Cell Differentiation in Spondyloarthritis per Anna Ridley, Hiroko Hatano, Isabel Wong‐Baeza, Jacqueline Shaw, Katherine Matthews, Hussein Al‐Mossawi, Kristin Ladell, David A. Price, Paul Bowness, Simon Kollnberger

    Publicat 2015
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  9. 9
    A Randomized, <scp>Placebo‐Controlled</scp> Phase <scp>III</scp> Extension Trial of the <scp>Long‐Term</scp> Safety and Tolerability of Anifrolumab in Active Systemic Lupus Erythematosus

    A Randomized, <scp>Placebo‐Controlled</scp> Phase <scp>III</scp> Extension Trial of the <scp>Long‐Term</scp> Safety and Tolerability of Anifrolumab in Active Systemic Lupus Erythem... per Kenneth Kalunian, Richard Furie, Eric F. Morand, Ian N Bruce, Susan Manzi, Yoshiya Tanaka, Kevin Winthrop, Ihor Hupka, Lijin Zhang, Shanti Werther, Gabriel Abreu, Micki Hultquist, Raj Tummala, Catharina Lindholm, Hussein Al‐Mossawi

    Publicat 2022
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  10. 10
    miR-10b-5p is a novel Th17 regulator present in Th17 cells from ankylosing spondylitis

    miR-10b-5p is a novel Th17 regulator present in Th17 cells from ankylosing spondylitis per L Chen, Hussein Al‐Mossawi, Anne J. Ridley, Takuya Sekine, Ariane Hammitzsch, Jelle de Wit, Davide Simone, Hui Shi, Frank Penkava, Mariola Kurowska‐Stolarska, Irina Pulyakhina, Julian C. Knight, Tae‐Jong Kim, Paul Bowness

    Publicat 2016
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  11. 11
    A randomised, parallel-group, double-blind, placebo-controlled phase 3 study to Determine the effectiveness of the type I interferon receptor antibody, Anifrolumab, In SYstemic sclerosis: DAISY study design and rationale

    A randomised, parallel-group, double-blind, placebo-controlled phase 3 study to Determine the effectiveness of the type I interferon receptor antibody, Anifrolumab, In SYstemic scl... per Dinesh Khanna, Christopher P. Denton, Shervin Assassi, Masataka Kuwana, Yannick Allanore, Robyn T. Domsic, C. Kleoudis, John Xu, Eszter Csomor, Caroline Seo, M. Albulescu, Raj Tummala, Hussein Al‐Mossawi, Rubana N. Kalyani, Francesco Del Galdo

    Publicat 2024
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  12. 12
    Peripheral CD8+ T cell characteristics associated with durable responses to immune checkpoint blockade in patients with metastatic melanoma

    Peripheral CD8+ T cell characteristics associated with durable responses to immune checkpoint blockade in patients with metastatic melanoma per Benjamin P. Fairfax, Chelsea Taylor, Robert Watson, Isar Nassiri, Sara Danielli, Hai Fang, Elise A. Mahé, Rosalin Cooper, Victoria K. Woodcock, Zoë Traill, Hussein Al‐Mossawi, Julian C. Knight, Paul Klenerman, Miranda Payne, Mark R. Middleton

    Publicat 2020
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  13. 13
    CBP30, a selective CBP/p300 bromodomain inhibitor, suppresses human Th17 responses

    CBP30, a selective CBP/p300 bromodomain inhibitor, suppresses human Th17 responses per Ariane Hammitzsch, C. Tallant, O. Fedorov, Alison O’Mahony, Paul E. Brennan, Duncan A. Hay, Fernando O. Martínez, Hussein Al‐Mossawi, Jelle de Wit, Matteo Vecellio, Christopher Wells, B P Wordsworth, Susanne Müller, Stefan Knapp, Paul Bowness

    Publicat 2015
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  14. 14
    Unique transcriptome signatures and GM-CSF expression in lymphocytes from patients with spondyloarthritis

    Unique transcriptome signatures and GM-CSF expression in lymphocytes from patients with spondyloarthritis per Hussein Al‐Mossawi, L. Chen, Hai Fang, Anne J. Ridley, Jelle de Wit, Nicole Yager, Ariane Hammitzsch, Irina Pulyakhina, Benjamin P. Fairfax, Davide Simone, Yao Yi, Soham Bandyopadhyay, K Doig, Roger Gundle, Benjamin Kendrick, Fiona Powrie, Julian C. Knight, Paul Bowness

    Publicat 2017
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  15. 15
    Context-specific regulation of surface and soluble IL7R expression by an autoimmune risk allele

    Context-specific regulation of surface and soluble IL7R expression by an autoimmune risk allele per Hussein Al‐Mossawi, Nicole Yager, Chelsea Taylor, Evelyn Lau, Sara Danielli, Jelle de Wit, James J. Gilchrist, Isar Nassiri, Elise A. Mahé, Wanseon Lee, Laila Rizvi, Seiko Makino, Jane Cheeseman, Matt J. Neville, Julian C. Knight, Paul Bowness, Benjamin P. Fairfax

    Publicat 2019
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  16. 16
    Type I interferon blockade with anifrolumab in patients with systemic lupus erythematosus modulates key immunopathological pathways in a gene expression and proteomic analysis of two phase 3 trials

    Type I interferon blockade with anifrolumab in patients with systemic lupus erythematosus modulates key immunopathological pathways in a gene expression and proteomic analysis of t... per Tina Baker, Hoda Sharifian, Paul J. Newcombe, Patrick G. Gavin, Mark Lazarus, Madhu Ramaswamy, Wendy I. White, Nicola Ferrari, Daniel Muthas, Raj Tummala, Eric F. Morand, Richard Furie, Edward M Vital, Chris Chamberlain, Adam Platt, Hussein Al‐Mossawi, Philip Z. Brohawn, Eszter Csomor

    Publicat 2024
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  17. 17
    Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis

    Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis per Frank Penkava, Martin Del Castillo Velasco‐Herrera, Matthew D. Young, Nicole Yager, L.N. Nwosu, Arthur G. Pratt, Alicia Lledó Lara, Charlotte Guzzo, Ash Maroof, Lira Mamanova, Suzanne Cole, Mirjana Efremova, Davide Simone, Andrew Filer, Chrysothemis C. Brown, Andrew L. Croxford, John D. Isaacs, Sarah A. Teichmann, Paul Bowness, Sam Behjati, Hussein Al‐Mossawi

    Publicat 2020
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  18. 18
    Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis

    Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis per Penkava, Frank, Velasco-Herrera, Martin Del Castillo, Young, Matthew D., Yager, Nicole, Nwosu, Lilian N., Pratt, Arthur G., Lara, Alicia Lledo, Guzzo, Charlotte, Maroof, Ash, Mamanova, Lira, Cole, Suzanne, Efremova, Mirjana, Simone, Davide, Filer, Andrew, Brown, Chrysothemis C., Croxford, Andrew L., Isaacs, John D., Teichmann, Sarah, Bowness, Paul, Behjati, Sam, Hussein Al-Mossawi, M.

    Publicat 2020
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  19. 19
    Towards stratified treatment of JIA: machine learning identifies subtypes in response to methotrexate from four UK cohorts

    Towards stratified treatment of JIA: machine learning identifies subtypes in response to methotrexate from four UK cohorts per Stephanie Shoop-Worrall, Saskia Lawson‐Tovey, Lucy R. Wedderburn, Kimme L Hyrich, Nophar Geifman, Aline Kimonyo, Alyssia McNeece, Andrew D. Dick, Andrew P. Morris, Annie Yarwood, Athimalaipet V Ramanan, Bethany R. Jebson, Chris Wallace, Daniela Dastros-Pitei, Damian Tarasek, Elizabeth Ralph, Emil Carlsson, Emily Robinson, E. Sumner, Fatema Merali, Fatjon Dekaj, Helen Neale, Hussein Al‐Mossawi, Jacqui Roberts, Jenna F. Gritzfeld, Joanna Fairlie, John Bowes, J Ioannou, Kimme L Hyrich, Lucy R. Wedderburn, Melissa Kartawinata, Melissa Tordoff, Michael Barnes, Michael W. Beresford, Michael A. Stadler, Nophar Geifman, Paul Martin, Rami Kallala, Sandra Ng, Samantha Smith, Sarah Clarke, Saskia Lawson‐Tovey, Soumya Raychaudhuri, Stephanie Shoop-Worrall, Stephen Eyre, Sumanta Mukherjee, Teresa Duerr, Thierry Sornasse, Vasiliki Alexiou, Victoria J. Burton, Wei‐Yu Lin, Wendy Thomson, Zoe Wanstall

    Publicat 2024
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  20. 20
    Towards a novel clinical outcome assessment for systemic lupus erythematosus: first outcomes of an international taskforce

    Towards a novel clinical outcome assessment for systemic lupus erythematosus: first outcomes of an international taskforce per Kathryn Connelly, Laura Eades, Rachel Koelmeyer, Darshini Ayton, Vera Golder, Rangi Kandane‐Rathnayake, Kate Gregory, Hermine I. Brunner, Laurie B. Burke, Laurent Arnaud, Anca Askanase, Cynthia Aranow, Edward M Vital, Guillermo Pons‐Estel, Khadija Dantata, Jeanette Andersen, Alain Cornet, Joy Buie, Ying Sun, Yoshiya Tanaka, Lee S. Simon, Youmna Lahoud, Alan Friedman, Kenneth Kalunian, Qing Zuraw, Victoria P. Werth, Sandra Garcês, Eric F. Morand, Alessandro Sorrentino, Anna Stevens, Catherine Barbey, Elaine Karis, Eric F. Morand, Erika H. Noss, Eve Smith, George Stojan, J Terés, Justine Maller, Maya Hojnik, Nikolay Delev, Laura Eades, Maria Dall’Era, Patrick Marquis, Richard Furie, Ronald van Vollenhoven, Tim Coulom, Cailin H. Sibley, C. Stach, Cristina Vazquez‐Mateo, E.S. Zollars, Heath Guay, Hussein Al‐Mossawi, Joan T. Merrill, Jorge Ross Terrés, Karen H. Costenbader, Maria Silk, Marta Mosca, Nicki Bush, Subhashis Banerjee, Thierry Sornasse, Blanca Rubio, Dalila Tremarias, Dalilah Kalla, Gonzalo Tobar Carrizo, Imasha Adisa, Shiori Nagamori, Sibongile Komati, S.M. Scoggins, Susanne Gydesen, T. M. Grimes, Vinita Haroun, Zoe Karakikla-Mitsa, Ann Eldred, Bianca Fedriz, C. Lindholm, Charlotte Lupton, Dennis M. Grasela, Erik R. Thomas, Maria Juárez, Nitin Kumar, O Guenther, Samantha Pomponi, Sanjeev Roy, Shelly Kafka, Thomas Morel, Yulia Pincus

    Publicat 2023
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