檢索結果 - Hubbard, Roderick

Fragment approaches in structure-based drug discovery 由 Hubbard, Roderick E.

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Current perspectives in fragment-based lead discovery (FBLD) 由 Lamoree, Bas, Hubbard, Roderick E.

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Using Fragment-Based Approaches to Discover New Antibiotics 由 Lamoree, Bas, Hubbard, Roderick E.

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sgTarget: a target selection resource for structural genomics 由 Rodrigues, Ana P. C., Grant, Barry J., Hubbard, Roderick E.

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Exploring IDP–Ligand Interactions: Tau K18 as a Test Case 由 Vagrys, Darius, Davidson, James, Chen, Ijen, Hubbard, Roderick E., Davis, Ben

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1D NMR WaterLOGSY as an efficient method for fragment-based lead discovery 由 Raingeval, Claire, Cala, Olivier, Brion, Béatrice, Le Borgne, Marc, Hubbard, Roderick Eliot, Krimm, Isabelle

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Correction to: (1)H, (13)C, (15)N backbone and IVL methyl group resonance assignment of the fungal β-glucosidase from Trichoderma reesei 由 Makraki, Eleni, Carneiro, Marta G., Heyam, Alex, AB, Eiso, Siegal, Gregg, Hubbard, Roderick E.

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Discovery of Selective Small-Molecule Activators of a Bacterial Glycoside Hydrolase** 由 Darby, John F, Landström, Jens, Roth, Christian, He, Yuan, Davies, Gideon J, Hubbard, Roderick E

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(1)H, (13)C, (15)N backbone and IVL methyl group resonance assignment of the fungal β-glucosidase from Trichoderma reesei 由 Makraki, Eleni, Carneiro, Marta G., Heyam, Alex, Eiso, A. B., Siegal, Gregg, Hubbard, Roderick E.

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Delineation of a unique protein–protein interaction site on the surface of the estrogen receptor 由 Kong, Eric H., Heldring, Nina, Gustafsson, Jan-Åke, Treuter, Eckardt, Hubbard, Roderick E., Pike, Ashley C. W.

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Increase of enzyme activity through specific covalent modification with fragments 由 Darby, John F., Atobe, Masakazu, Firth, James D., Bond, Paul, Davies, Gideon J., O'Brien, Peter, Hubbard, Roderick E.

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P-Rex1 Controls Sphingosine 1-Phosphate Receptor Signalling, Morphology, and Cell-Cycle Progression in Neuronal Cells 由 Hampson, Elizabeth, Tsonou, Elpida, Baker, Martin J., Hornigold, David C., Hubbard, Roderick E., Massey, Andrew, Welch, Heidi C. E.

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rDock: A Fast, Versatile and Open Source Program for Docking Ligands to Proteins and Nucleic Acids 由 Ruiz-Carmona, Sergio, Alvarez-Garcia, Daniel, Foloppe, Nicolas, Garmendia-Doval, A. Beatriz, Juhos, Szilveszter, Schmidtke, Peter, Barril, Xavier, Hubbard, Roderick E., Morley, S. David

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Fragment-derived modulators of an industrial β-glucosidase 由 Makraki, Eleni, Darby, John F., Carneiro, Marta G., Firth, James D., Heyam, Alex, Ab, Eiso, O'Brien, Peter, Siegal, Gregg, Hubbard, Roderick E.

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Supply of Neuraminidase Inhibitors Related to Reduced Influenza A (H1N1) Mortality during the 2009–2010 H1N1 Pandemic: An Ecological Study 由 Miller, Paula E., Rambachan, Aksharananda, Hubbard, Roderick J., Li, Jiabai, Meyer, Alison E., Stephens, Peter, Mounts, Anthony W., Rolfes, Melissa A., Penn, Charles R.

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Supply of neuraminidase inhibitors related to reduced influenza A (H1N1) mortality during the 2009–2010 H1N1 pandemic: summary of an ecological study 由 Miller, Paula E., Rambachan, Aksharananda, Hubbard, Roderick J., Li, Jiabai, Meyer, Alison E., Stephens, Peter, Mounts, Anthony W., Rolfes, Melissa A., Penn, Charles R.

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The Effect of Core Replacement on S64315, a Selective MCL-1 Inhibitor, and Its Analogues 由 Sipos, Szabolcs, Bálint, Balázs, Szabó, Zoltán B., Ondi, Levente, Csékei, Márton, Szlávik, Zoltán, Proszenyák, Ágnes, Murray, James B., Davidson, James, Chen, Ijen, Dokurno, Pawel, Surgenor, Allan E., Pedder, Christopher, Hubbard, Roderick E., Maragno, Ana-Leticia, Chanrion, Maia, Colland, Frederic, Geneste, Olivier, Kotschy, András

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Design and Synthesis of 56 Shape‐Diverse 3D Fragments 由 Downes, Thomas D., Jones, S. Paul, Klein, Hanna F., Wheldon, Mary C., Atobe, Masakazu, Bond, Paul S., Firth, James D., Chan, Ngai S., Waddelove, Laura, Hubbard, Roderick E., Blakemore, David C., De Fusco, Claudia, Roughley, Stephen D., Vidler, Lewis R., Whatton, Maria Ann, Woolford, Alison J.‐A., Wrigley, Gail L., O'Brien, Peter

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Establishing Drug Discovery and Identification of Hit Series for the Anti-apoptotic Proteins, Bcl-2 and Mcl-1 由 Murray, James B., Davidson, James, Chen, Ijen, Davis, Ben, Dokurno, Pawel, Graham, Christopher J., Harris, Richard, Jordan, Allan, Matassova, Natalia, Pedder, Christopher, Ray, Stuart, Roughley, Stephen D., Smith, Julia, Walmsley, Claire, Wang, Yikang, Whitehead, Neil, Williamson, Douglas S., Casara, Patrick, Le Diguarher, Thierry, Hickman, John, Stark, Jerome, Kotschy, András, Geneste, Olivier, Hubbard, Roderick E.

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S55746 is a novel orally active BCL-2 selective and potent inhibitor that impairs hematological tumor growth 由 Casara, Patrick, Davidson, James, Claperon, Audrey, Le Toumelin-Braizat, Gaëtane, Vogler, Meike, Bruno, Alain, Chanrion, Maïa, Lysiak-Auvity, Gaëlle, Le Diguarher, Thierry, Starck, Jérôme-Benoît, Chen, Ijen, Whitehead, Neil, Graham, Christopher, Matassova, Natalia, Dokurno, Pawel, Pedder, Christopher, Wang, Youzhen, Qiu, Shumei, Girard, Anne-Marie, Schneider, Emilie, Gravé, Fabienne, Studeny, Aurélie, Guasconi, Ghislaine, Rocchetti, Francesca, Maïga, Sophie, Henlin, Jean-Michel, Colland, Frédéric, Kraus-Berthier, Laurence, Le Gouill, Steven, Dyer, Martin J.S., Hubbard, Roderick, Wood, Mike, Amiot, Martine, Cohen, Gerald M, Hickman, John A., Morris, Erick, Murray, James, Geneste, Olivier

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